CN103237890A - 用于产生rna 病毒的方法和辅助病毒 - Google Patents

用于产生rna 病毒的方法和辅助病毒 Download PDF

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Publication number
CN103237890A
CN103237890A CN201180041228XA CN201180041228A CN103237890A CN 103237890 A CN103237890 A CN 103237890A CN 201180041228X A CN201180041228X A CN 201180041228XA CN 201180041228 A CN201180041228 A CN 201180041228A CN 103237890 A CN103237890 A CN 103237890A
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virus
albumen
helper virus
helper
particle
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CN201180041228XA
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Chinese (zh)
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T.马斯特
A.埃戈罗夫
M.沃谢克
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Baxter Healthcare SA
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Baxter Healthcare SA
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
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    • C12N2760/00011—Details
    • C12N2760/00051—Methods of production or purification of viral material
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material
    • C12N2760/16152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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  • Life Sciences & Earth Sciences (AREA)
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  • Genetics & Genomics (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • Biotechnology (AREA)
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  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201180041228XA 2010-06-02 2011-06-06 用于产生rna 病毒的方法和辅助病毒 Pending CN103237890A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10164779.0 2010-06-02
EP10164779 2010-06-02
PCT/EP2011/059284 WO2011151470A2 (en) 2010-06-02 2011-06-06 Novel method for generation of rna virus

Publications (1)

Publication Number Publication Date
CN103237890A true CN103237890A (zh) 2013-08-07

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CN201180041228XA Pending CN103237890A (zh) 2010-06-02 2011-06-06 用于产生rna 病毒的方法和辅助病毒

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US (1) US20130183740A1 (https=)
EP (1) EP2576773A2 (https=)
JP (1) JP2013529913A (https=)
KR (1) KR20130115105A (https=)
CN (1) CN103237890A (https=)
CA (1) CA2801268A1 (https=)
EA (1) EA201201620A1 (https=)
WO (1) WO2011151470A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103865923A (zh) * 2014-01-28 2014-06-18 中国人民解放军第三0二医院 流感病毒为载体的HAdV嵌合疫苗的制备及其应用
WO2020042359A1 (zh) * 2018-08-28 2020-03-05 青岛农业大学 一种同时表达ha和hef的复制缺陷型重组流感病毒

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009000891A2 (en) * 2007-06-27 2008-12-31 Avir Green Hills Biotechnology Research Development Trade Ag Linear expression constructs for production of influenza virus particles
CN101379183A (zh) * 2004-12-24 2009-03-04 索尔瓦药物有限公司 流感病毒的拯救
CN102239250A (zh) * 2008-12-03 2011-11-09 阿维尔绿山生物技术研究发展贸易股份公司 用于生成rna病毒的新方法

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FR2737501B1 (fr) * 1995-07-31 1997-10-24 Transgene Sa Nouveaux virus auxiliaires pour la preparation de vecteurs viraux recombinants
ATE384126T1 (de) 1998-06-12 2008-02-15 Sinai School Medicine Interferon induzierende genetisch veränderte attenuierte viren
KR100637937B1 (ko) 1998-06-12 2006-10-23 마운트 시나이 스쿨 오브 메디신 오브 뉴욕 유니버시티 변형된 인터페론 길항물질을 보유하고, 백신 및 약제로사용되는 약독화된 네거티브 가닥 바이러스
WO2000056914A1 (en) 1999-03-24 2000-09-28 Gene Therapy Systems, Inc. Method for generating transcriptionally active dna fragments
EP1820853B1 (en) 1999-04-06 2011-09-21 Wisconsin Alumni Research Foundation Recombinant influenza viruses for vaccines and gene therapy
ES2278621T5 (es) 1999-07-14 2011-02-02 Mount Sinai School Of Medicine Of New York University Reconstrucción in vitro de virus arn segmentados de polaridad negativa.
MXPA02010642A (es) * 2000-04-28 2004-05-17 St Jude Children S Res Hospital Sistema de transfeccion de adn para la generacion de virus de influenza infeccioso.
EP1470218B1 (en) * 2001-05-17 2010-07-07 Universiteit Utrecht Corona-virus-like particles comprising functionally deleted genomes
DE10248301A1 (de) * 2002-10-16 2004-04-29 Philipps-Universität Marburg Herstellung eines Lebend-Impfstoffes gegen Influenza-Viren
EP2048237A1 (en) * 2007-10-05 2009-04-15 Avir Green Hills Biotechnology Research Development Trade Ag Replication deficient Influenza virus for the expression of heterologous sequences
US8815252B2 (en) * 2008-11-25 2014-08-26 Baxter Healthcare Sa Method for production of pH stable enveloped viruses
EP2233152A1 (en) * 2009-03-24 2010-09-29 Avir Green Hills Biotechnology Research Development Trade Ag High growth reassortant influenza A virus
US9771564B2 (en) * 2009-07-22 2017-09-26 Nanotherapeutics, Inc. Influenza virus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101379183A (zh) * 2004-12-24 2009-03-04 索尔瓦药物有限公司 流感病毒的拯救
WO2009000891A2 (en) * 2007-06-27 2008-12-31 Avir Green Hills Biotechnology Research Development Trade Ag Linear expression constructs for production of influenza virus particles
CN102239250A (zh) * 2008-12-03 2011-11-09 阿维尔绿山生物技术研究发展贸易股份公司 用于生成rna病毒的新方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MAKOTO OZAWA等: "An Adenovirus Vector-Mediated Reverse Genetics System for Influenza A Virus Generation", 《JOURNAL OF VIROLOGY》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103865923A (zh) * 2014-01-28 2014-06-18 中国人民解放军第三0二医院 流感病毒为载体的HAdV嵌合疫苗的制备及其应用
WO2020042359A1 (zh) * 2018-08-28 2020-03-05 青岛农业大学 一种同时表达ha和hef的复制缺陷型重组流感病毒

Also Published As

Publication number Publication date
JP2013529913A (ja) 2013-07-25
WO2011151470A2 (en) 2011-12-08
US20130183740A1 (en) 2013-07-18
WO2011151470A3 (en) 2012-11-08
CA2801268A1 (en) 2011-12-08
EA201201620A1 (ru) 2013-07-30
KR20130115105A (ko) 2013-10-21
EP2576773A2 (en) 2013-04-10

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