JP2013538588A5 - - Google Patents
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- JP2013538588A5 JP2013538588A5 JP2013532180A JP2013532180A JP2013538588A5 JP 2013538588 A5 JP2013538588 A5 JP 2013538588A5 JP 2013532180 A JP2013532180 A JP 2013532180A JP 2013532180 A JP2013532180 A JP 2013532180A JP 2013538588 A5 JP2013538588 A5 JP 2013538588A5
- Authority
- JP
- Japan
- Prior art keywords
- cell culture
- suspension
- hemostatic
- protein
- filter module
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10186545.9 | 2010-10-05 | ||
| EP10186545 | 2010-10-05 | ||
| US39271310P | 2010-10-13 | 2010-10-13 | |
| US61/392,713 | 2010-10-13 | ||
| PCT/EP2011/067372 WO2012045769A1 (en) | 2010-10-05 | 2011-10-05 | Process for protein production |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016153606A Division JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013538588A JP2013538588A (ja) | 2013-10-17 |
| JP2013538588A5 true JP2013538588A5 (https=) | 2014-11-20 |
| JP6282467B2 JP6282467B2 (ja) | 2018-02-21 |
Family
ID=43735957
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532180A Active JP6282467B2 (ja) | 2010-10-05 | 2011-10-05 | タンパク質を生産するための方法 |
| JP2016153606A Withdrawn JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016153606A Withdrawn JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10138290B2 (https=) |
| EP (2) | EP2625262B1 (https=) |
| JP (2) | JP6282467B2 (https=) |
| CN (2) | CN107190034A (https=) |
| ES (1) | ES2556454T3 (https=) |
| PL (1) | PL2625262T3 (https=) |
| WO (1) | WO2012045769A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104583386A (zh) * | 2012-08-20 | 2015-04-29 | 泰尔茂比司特公司 | 浓缩穿过细胞生长腔室循环的流体的组分 |
| KR102245547B1 (ko) * | 2013-09-30 | 2021-04-28 | 얀센 백신스 앤드 프리벤션 비.브이. | 고밀도의 미정제 세포 배양 수거물의 정화를 위한 방법 |
| JP6530171B2 (ja) * | 2014-09-09 | 2019-06-12 | 旭化成メディカル株式会社 | 培養産生物の回収方法 |
| JP7102391B2 (ja) * | 2016-07-25 | 2022-07-19 | レプリゲン・コーポレイション | 交互タンジェンシャルフローによる高速収穫 |
| WO2019084410A1 (en) | 2017-10-26 | 2019-05-02 | Repligen Corporation | MICRO-ALTERNATIVE TANGENTIALLY FLOWING INFUSION FILTER, TREATMENT CONTAINER, AND METHODS OF USING THE SAME |
| TWI846694B (zh) * | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| CN108504562A (zh) * | 2018-06-21 | 2018-09-07 | 江苏澳创生物科技有限公司 | 一种发酵生产l-苏氨酸的系统及其应用 |
| CA3144125A1 (en) * | 2019-07-16 | 2021-01-21 | Haihong Sun | Cell culture method based on high-density and continuous inoculation and use thereof |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE74164T1 (de) | 1985-04-22 | 1992-04-15 | Genetics Inst | Herstellung mit hoher leistung des aktivfaktors ix. |
| DE3785102T2 (de) | 1986-01-03 | 1993-07-22 | Genetics Inst | Verfahren zur herstellung von faktor-viii:c-typ-proteinen. |
| CA1331157C (en) | 1987-04-06 | 1994-08-02 | Randal J. Kaufman | Method for producing factor viii:c-type proteins |
| US4956080A (en) * | 1987-08-03 | 1990-09-11 | Microlift Systems, Incorporated | High pressure oxygen-saturated water treatment apparatus |
| JPH066054B2 (ja) | 1987-10-15 | 1994-01-26 | 帝人株式会社 | 動物細胞の培養方法 |
| JPH084495B2 (ja) | 1988-08-19 | 1996-01-24 | 帝人株式会社 | 接着性動物細胞の培養方法 |
| WO1990002175A1 (en) | 1988-08-16 | 1990-03-08 | Novo Nordisk A/S | A method of producing polypeptides by culturing eukaryotic cells in the presence of protease inhibitors |
| US6268487B1 (en) | 1996-05-13 | 2001-07-31 | Genzyme Transgenics Corporation | Purification of biologically active peptides from milk |
| US5851800A (en) | 1996-05-14 | 1998-12-22 | Pharmacia & Upjohn Ab | Process for producing a protein |
| AT409379B (de) * | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| US6544424B1 (en) | 1999-12-03 | 2003-04-08 | Refined Technology Company | Fluid filtration system |
| CA2426084C (en) | 2000-10-20 | 2013-12-10 | Bioteknologisk Institut | Improved fermentation method for production of heterologous gene products in lactic acid bacteria |
| JP2005512524A (ja) | 2001-11-02 | 2005-05-12 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | ヒト凝固第ｖｉｉ因子ポリペプチド |
| US6960657B2 (en) | 2001-11-02 | 2005-11-01 | Novo Nordisk Healthcare A/G | Human coagulation factor VII polypeptides |
| RU2362807C2 (ru) | 2002-06-21 | 2009-07-27 | Ново Нордиск Хелт Кэр Аг | Конъюгат полипептида фактора vii, способ его получения, его применение и содержащая его фармацевтическая композиция |
| US7351688B2 (en) | 2003-02-05 | 2008-04-01 | The Research Foundation Of State University Of New York | Compositions and methods for less immunogenic protein formulations |
| DE602004008451T2 (de) | 2003-05-01 | 2008-05-15 | Dsm Ip Assets B.V. | Verfahren zur herstellung von biologischen substanzen durch perfusionskultivierung von suspendierten tierischen zellen |
| CN100383238C (zh) | 2003-05-09 | 2008-04-23 | 克鲁塞尔荷兰公司 | E1-永生化的细胞培养物及培养所述细胞以提高从中获取的产物产量的方法 |
| JP4740138B2 (ja) | 2003-10-10 | 2011-08-03 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 真核生物細胞におけるポリペプチドの大規模生産方法及びそれに適した培養容器 |
| CA2557046A1 (en) * | 2004-03-05 | 2005-10-13 | John Crowley | Process for cell culturing by continuous perfusion and alternating tangential flow |
| ATE469216T1 (de) | 2004-08-17 | 2010-06-15 | Csl Behring Gmbh | Modifizierte vitamin-k-abhängige polypeptide |
| EP1707634A1 (en) | 2005-03-29 | 2006-10-04 | Octapharma AG | Method for isolation of recombinantly produced proteins |
| WO2007124106A2 (en) | 2006-04-21 | 2007-11-01 | Bayer Healthcare Llc | Application of antl-apoptotic genes in mammalian cells for perfusion culture. |
| SI2041259T1 (sl) * | 2006-07-14 | 2016-04-29 | Dpx Holdings B.V. | Izboljšan postopek kultiviranja celic |
| CN101490239A (zh) * | 2006-07-14 | 2009-07-22 | 帝斯曼知识产权资产管理有限公司 | 改进的细胞培养方法 |
| EP1988101A1 (en) | 2007-05-04 | 2008-11-05 | Novo Nordisk A/S | Improvement of factor VIII polypeptide titers in cell cultures |
| EP2014760A1 (en) * | 2007-06-13 | 2009-01-14 | CMC Biopharmaceuticals A/S | A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process |
| JP2009045019A (ja) | 2007-08-21 | 2009-03-05 | Toray Ind Inc | タンパク質の製造方法 |
| CN102105582A (zh) | 2008-04-21 | 2011-06-22 | 诺沃-诺迪斯克有限公司 | 高糖基化人凝血因子ix |
| WO2010003759A2 (en) | 2008-06-17 | 2010-01-14 | Dsm Ip Assets B.V. | Cell culturing method |
-
2011
- 2011-10-05 CN CN201710499437.8A patent/CN107190034A/zh active Pending
- 2011-10-05 CN CN2011800482244A patent/CN103154233A/zh active Pending
- 2011-10-05 WO PCT/EP2011/067372 patent/WO2012045769A1/en not_active Ceased
- 2011-10-05 JP JP2013532180A patent/JP6282467B2/ja active Active
- 2011-10-05 PL PL11764561T patent/PL2625262T3/pl unknown
- 2011-10-05 EP EP11764561.4A patent/EP2625262B1/en not_active Revoked
- 2011-10-05 ES ES11764561.4T patent/ES2556454T3/es active Active
- 2011-10-05 US US13/823,847 patent/US10138290B2/en active Active
- 2011-10-05 EP EP15174742.5A patent/EP2957628A1/en not_active Withdrawn
-
2016
- 2016-08-04 JP JP2016153606A patent/JP2016187360A/ja not_active Withdrawn
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