JP2011504721A5 - - Google Patents

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Publication number
JP2011504721A5
JP2011504721A5 JP2010509679A JP2010509679A JP2011504721A5 JP 2011504721 A5 JP2011504721 A5 JP 2011504721A5 JP 2010509679 A JP2010509679 A JP 2010509679A JP 2010509679 A JP2010509679 A JP 2010509679A JP 2011504721 A5 JP2011504721 A5 JP 2011504721A5
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JP
Japan
Prior art keywords
polyclonal
cells
protein
cell line
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2010509679A
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English (en)
Japanese (ja)
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JP2011504721A (ja
JP5941616B2 (ja
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Application filed filed Critical
Priority claimed from PCT/DK2008/050116 external-priority patent/WO2008145133A2/en
Publication of JP2011504721A publication Critical patent/JP2011504721A/ja
Publication of JP2011504721A5 publication Critical patent/JP2011504721A5/ja
Application granted granted Critical
Publication of JP5941616B2 publication Critical patent/JP5941616B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010509679A 2007-05-25 2008-05-21 組み換えポリクローナルタンパク質を製造する方法 Expired - Fee Related JP5941616B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
DKPA200700764 2007-05-25
DKPA200700764 2007-05-25
US92470807P 2007-05-29 2007-05-29
US60/924,708 2007-05-29
DKPA200701292 2007-09-07
DKPA200701292 2007-09-07
US96000207P 2007-09-11 2007-09-11
US60/960,002 2007-09-11
PCT/DK2008/050116 WO2008145133A2 (en) 2007-05-25 2008-05-21 Method for manufacturing a recombinant polyclonal protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014191912A Division JP2015037411A (ja) 2007-05-25 2014-09-19 組み換えポリクローナルタンパク質を製造する方法

Publications (3)

Publication Number Publication Date
JP2011504721A JP2011504721A (ja) 2011-02-17
JP2011504721A5 true JP2011504721A5 (enExample) 2011-07-07
JP5941616B2 JP5941616B2 (ja) 2016-06-29

Family

ID=39739965

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010509679A Expired - Fee Related JP5941616B2 (ja) 2007-05-25 2008-05-21 組み換えポリクローナルタンパク質を製造する方法
JP2014191912A Pending JP2015037411A (ja) 2007-05-25 2014-09-19 組み換えポリクローナルタンパク質を製造する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014191912A Pending JP2015037411A (ja) 2007-05-25 2014-09-19 組み換えポリクローナルタンパク質を製造する方法

Country Status (22)

Country Link
US (1) US7910332B2 (enExample)
EP (1) EP2152872B1 (enExample)
JP (2) JP5941616B2 (enExample)
KR (1) KR101555658B1 (enExample)
CN (1) CN101688204B (enExample)
AT (1) ATE481483T1 (enExample)
AU (1) AU2008255383B2 (enExample)
BR (1) BRPI0812091A2 (enExample)
CA (1) CA2683800C (enExample)
CY (1) CY1110939T1 (enExample)
DE (1) DE602008002593D1 (enExample)
DK (1) DK2152872T3 (enExample)
HR (1) HRP20100640T1 (enExample)
IL (1) IL201395A (enExample)
MX (1) MX2009012526A (enExample)
NZ (1) NZ581316A (enExample)
PL (1) PL2152872T3 (enExample)
PT (1) PT2152872E (enExample)
SI (1) SI2152872T1 (enExample)
TW (1) TW200902548A (enExample)
WO (1) WO2008145133A2 (enExample)
ZA (1) ZA200908021B (enExample)

Families Citing this family (28)

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Publication number Priority date Publication date Assignee Title
CA2512647C (en) 2003-01-07 2013-10-08 Symphogen A/S Method for manufacturing recombinant polyclonal proteins
MX2009008908A (es) * 2007-03-01 2009-08-28 Symphogen As Metodo para clonacion de anticuerpos analogos.
NZ581316A (en) * 2007-05-25 2012-02-24 Symphogen As Method for manufacturing a recombinant polyclonal protein
CN101821289A (zh) * 2007-09-07 2010-09-01 西福根有限公司 重组制造抗rsv抗体的方法
CA2713885A1 (en) * 2008-02-01 2009-08-20 Chromocell Corporation Novel cell lines and methods
EP2098536A1 (en) 2008-03-05 2009-09-09 4-Antibody AG Isolation and identification of antigen- or ligand-specific binding proteins
BRPI0910454A2 (pt) * 2008-04-23 2018-03-27 Symphogen As processo para produção de uma proteína policlonal
EP2297331B1 (en) * 2008-05-28 2015-03-25 Bayer HealthCare, LLC Methods and compositions for production of recombinant protein in hbx-expressing mammalian cells
MX2011001930A (es) * 2008-08-29 2011-04-21 Symphogen As Metodo para clonar anticuerpos derivados de aves.
DK2393927T3 (en) 2009-02-09 2015-03-30 Morphosys Ag Preparation of oligoclonal mixtures of antibodies in the individual cells
ES2692379T3 (es) 2010-11-01 2018-12-03 Symphogen A/S Anticuerpos anti-HER3 y composiciones
CA2817751C (en) 2010-11-16 2019-04-30 Excelimmune, Inc. Methods for producing recombinant proteins
CN102558353A (zh) * 2011-12-09 2012-07-11 上海应用技术学院 一种大肠杆菌NrfA基因表达蛋白多克隆抗体及其制备方法
GB2502127A (en) 2012-05-17 2013-11-20 Kymab Ltd Multivalent antibodies and in vivo methods for their production
WO2013164689A2 (en) 2012-05-02 2013-11-07 Lantto, Johan Humanized pan-her antibody compositions
JP2016514091A (ja) 2013-02-08 2016-05-19 ミスフォールディング ダイアグノスティクス, インコーポレイテッド トランスサイレチン抗体およびその使用
WO2016042412A1 (en) 2014-09-16 2016-03-24 Symphogen A/S Anti-met antibodies and compositions
US12404552B2 (en) * 2015-07-17 2025-09-02 Allele Biotechnology & Pharmaceuticals, Inc. Methods of selecting antibodies and antibody fragments
JP2019501658A (ja) * 2016-01-14 2019-01-24 アントン バウアーAnton Bauer 生産用細胞株を作製する方法
WO2018073393A2 (en) 2016-10-19 2018-04-26 Cellectis Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
CN110621698B (zh) 2017-04-05 2024-04-12 法国施维雅药厂 靶向pd-1、tim-3及lag-3的组合疗法
MA52945A (fr) 2018-06-22 2021-04-28 Genmab As Procédé de production d'un mélange contrôlé d'au moins deux anticorps différents
CA3118692A1 (en) 2018-11-06 2020-05-14 Alsatech, Inc. Cell-based gene therapy for neurodegenerative diseases
CN109988751A (zh) * 2019-01-15 2019-07-09 济宁学院 一种用于制备抗egfr全人源化单克隆抗体的细胞株构建方法
AU2020264492A1 (en) * 2019-04-30 2021-10-14 Gigagen, Inc. Recombinant polyclonal proteins and methods of use thereof
WO2021058709A1 (en) * 2019-09-27 2021-04-01 Glaxosmithkline Intellectual Property Development Limited Method of predicting production stability of clonal cell lines
CA3177152A1 (en) 2020-06-12 2021-12-16 David Scott Johnson Recombinant polyclonal proteins targeting covid-19 and methods of use thereof
WO2024240634A1 (en) 2023-05-19 2024-11-28 Les Laboratoires Servier Anti-met antibodies, antibody-drug conjugates, compositions and uses thereof

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
WO1991016074A1 (en) 1990-04-19 1991-10-31 Medimmune, Inc. Administration of monoclonal antibodies against respiratory viruses
GB9022543D0 (en) * 1990-10-17 1990-11-28 Wellcome Found Antibody production
US6111166A (en) 1994-09-19 2000-08-29 Medarex, Incorporated Transgenic mice expressing human Fcα and β receptors
GB9703369D0 (en) 1997-02-18 1997-04-09 Lindqvist Bjorn H Process
WO2001094571A1 (fr) * 2000-06-08 2001-12-13 Mitsubishi Pharma Corporation Vecteur d'expression permettant le criblage de cellules a haute expression de proteine de recombinaison, transformant a haute expression de proteine de recombinaison, et leur utilisation
US6849259B2 (en) 2000-06-16 2005-02-01 Symphogen A/S Polyclonal antibody composition for treating allergy
SI1523496T1 (sl) * 2002-07-18 2011-11-30 Merus B V Rekombinantno proizvajanje zmesi protiteles
US20040115814A1 (en) * 2002-09-30 2004-06-17 Protein Design Labs, Inc. Efficient generation of stable expression cell lines through the use of scorable homeostatic reporter genes
CN100383244C (zh) * 2003-01-07 2008-04-23 西福根有限公司 用于生产重组多克隆蛋白质的方法
CA2512647C (en) * 2003-01-07 2013-10-08 Symphogen A/S Method for manufacturing recombinant polyclonal proteins
US20060275766A1 (en) 2003-01-07 2006-12-07 Haurum John S Method for manufacturing recombinant polyclonal proteins
TWI333977B (en) * 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
BRPI0513706A (pt) * 2004-07-20 2008-05-13 Symphogen As anticorpo policlonal recombinante anti-rhesus d e métodos de produção
RU2426795C2 (ru) * 2004-07-20 2011-08-20 Симфоген А/С Способ структурной характеристики рекомбинантного поликлонального белка или поликлональной клеточной линии
JP2009518320A (ja) 2005-12-05 2009-05-07 シュムフォウエン アクティーゼルスカブ 抗オルトポックスウイルス組換えポリクローナル抗体
KR20080113223A (ko) 2006-03-06 2008-12-29 심포젠 에이/에스 호흡기세포 융합 바이러스 감염 치료용 재조합 폴리클로날 항체
NZ581316A (en) * 2007-05-25 2012-02-24 Symphogen As Method for manufacturing a recombinant polyclonal protein

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