JP2010535252A5 - - Google Patents
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- JP2010535252A5 JP2010535252A5 JP2010520219A JP2010520219A JP2010535252A5 JP 2010535252 A5 JP2010535252 A5 JP 2010535252A5 JP 2010520219 A JP2010520219 A JP 2010520219A JP 2010520219 A JP2010520219 A JP 2010520219A JP 2010535252 A5 JP2010535252 A5 JP 2010535252A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- diabetes
- type
- metabolic
- nachr agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical group 0.000 claims 24
- 102000015296 acetylcholine-gated cation-selective channel activity proteins Human genes 0.000 claims 13
- 108040006409 acetylcholine-gated cation-selective channel activity proteins Proteins 0.000 claims 13
- 239000000556 agonist Substances 0.000 claims 13
- 206010012601 Diabetes mellitus Diseases 0.000 claims 12
- 208000008466 Metabolic Disease Diseases 0.000 claims 12
- 239000003814 drug Substances 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 10
- 239000011780 sodium chloride Substances 0.000 claims 10
- 201000001421 hyperglycemia Diseases 0.000 claims 9
- 239000003795 chemical substances by application Substances 0.000 claims 8
- 229940079593 drugs Drugs 0.000 claims 7
- 206010003210 Arteriosclerosis Diseases 0.000 claims 6
- 208000001145 Metabolic Syndrome Diseases 0.000 claims 6
- 208000008589 Obesity Diseases 0.000 claims 6
- 201000001320 atherosclerosis Diseases 0.000 claims 6
- 235000020824 obesity Nutrition 0.000 claims 6
- 208000009025 Nervous System Disease Diseases 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 201000008779 central nervous system disease Diseases 0.000 claims 1
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95361007P | 2007-08-02 | 2007-08-02 | |
US95361307P | 2007-08-02 | 2007-08-02 | |
US95361407P | 2007-08-02 | 2007-08-02 | |
US97165407P | 2007-09-12 | 2007-09-12 | |
PCT/US2008/071893 WO2009018511A2 (en) | 2007-08-02 | 2008-08-01 | Alpha7 nachr agonists for treating or preventing metabolic disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010535252A JP2010535252A (ja) | 2010-11-18 |
JP2010535252A5 true JP2010535252A5 (pt-PT) | 2011-01-06 |
Family
ID=39945177
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010520219A Pending JP2010535252A (ja) | 2007-08-02 | 2008-08-01 | 代謝障害を治療または予防するためのα7nAChRアゴニスト |
JP2010520213A Active JP5358573B2 (ja) | 2007-08-02 | 2008-08-01 | (2s,3r)−n−(2−((3−ピリジニル)メチル)−1−アザビシクロ[2.2.2]オクタ−3−イル)ベンゾフラン−2−カルボキサミド、その新規塩形態およびその使用方法 |
JP2013148091A Active JP6106549B2 (ja) | 2007-08-02 | 2013-07-17 | (2s,3r)−n−(2−((3−ピリジニル)メチル)−1−アザビシクロ[2.2.2]オクタ−3−イル)ベンゾフラン−2−カルボキサミド、その新規塩形態およびその使用方法 |
JP2013148087A Active JP5852611B2 (ja) | 2007-08-02 | 2013-07-17 | (2s,3r)−n−(2−((3−ピリジニル)メチル)−1−アザビシクロ[2.2.2]オクタ−3−イル)ベンゾフラン−2−カルボキサミド、その新規塩形態およびその使用方法 |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010520213A Active JP5358573B2 (ja) | 2007-08-02 | 2008-08-01 | (2s,3r)−n−(2−((3−ピリジニル)メチル)−1−アザビシクロ[2.2.2]オクタ−3−イル)ベンゾフラン−2−カルボキサミド、その新規塩形態およびその使用方法 |
JP2013148091A Active JP6106549B2 (ja) | 2007-08-02 | 2013-07-17 | (2s,3r)−n−(2−((3−ピリジニル)メチル)−1−アザビシクロ[2.2.2]オクタ−3−イル)ベンゾフラン−2−カルボキサミド、その新規塩形態およびその使用方法 |
JP2013148087A Active JP5852611B2 (ja) | 2007-08-02 | 2013-07-17 | (2s,3r)−n−(2−((3−ピリジニル)メチル)−1−アザビシクロ[2.2.2]オクタ−3−イル)ベンゾフラン−2−カルボキサミド、その新規塩形態およびその使用方法 |
Country Status (35)
Country | Link |
---|---|
US (6) | US20110124678A1 (pt-PT) |
EP (6) | EP2484363A1 (pt-PT) |
JP (4) | JP2010535252A (pt-PT) |
KR (2) | KR20100063043A (pt-PT) |
CN (4) | CN106831755A (pt-PT) |
AR (1) | AR067775A1 (pt-PT) |
AU (3) | AU2008283807B2 (pt-PT) |
BR (2) | BRPI0814889A2 (pt-PT) |
CA (2) | CA2694504C (pt-PT) |
CL (3) | CL2008002271A1 (pt-PT) |
CO (2) | CO6260080A2 (pt-PT) |
CY (1) | CY1113561T1 (pt-PT) |
DK (2) | DK2182949T3 (pt-PT) |
EC (2) | ECSP10010008A (pt-PT) |
ES (3) | ES2611139T3 (pt-PT) |
HK (1) | HK1140968A1 (pt-PT) |
HR (1) | HRP20130286T1 (pt-PT) |
HU (1) | HUE030387T2 (pt-PT) |
IL (1) | IL218976A0 (pt-PT) |
ME (1) | ME01508B (pt-PT) |
MX (3) | MX346748B (pt-PT) |
MY (1) | MY148002A (pt-PT) |
NO (2) | NO20100077L (pt-PT) |
NZ (2) | NZ582828A (pt-PT) |
PE (3) | PE20121821A1 (pt-PT) |
PL (1) | PL2182949T3 (pt-PT) |
PT (1) | PT2182949E (pt-PT) |
RS (1) | RS52743B (pt-PT) |
RU (2) | RU2012140182A (pt-PT) |
SA (2) | SA08290475B1 (pt-PT) |
SI (1) | SI2182949T1 (pt-PT) |
TW (3) | TW201402117A (pt-PT) |
UY (1) | UY31265A (pt-PT) |
WO (2) | WO2009018505A1 (pt-PT) |
ZA (1) | ZA201000719B (pt-PT) |
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WO2013142205A1 (en) | 2012-03-19 | 2013-09-26 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising benzyl alcohol |
CA2867123C (en) * | 2012-03-19 | 2021-02-16 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising water-insoluble antipsychotic agents and glycerol esters |
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WO2014153424A1 (en) * | 2013-03-19 | 2014-09-25 | La Jolla Institute For Allergy And Immunology | Reducing diabetes in patients receiving hmg-coa reductase inhibitors (statins) |
CN110368360A (zh) | 2014-03-20 | 2019-10-25 | 奥克梅斯制药爱尔兰有限公司 | 具有增加的注射速度的阿立哌唑制剂 |
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CN104288771B (zh) * | 2014-09-30 | 2017-03-15 | 郑州大学第五附属医院 | α7nAChR激动剂的新用途 |
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