JP2010513478A5 - - Google Patents
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- Publication number
- JP2010513478A5 JP2010513478A5 JP2009542710A JP2009542710A JP2010513478A5 JP 2010513478 A5 JP2010513478 A5 JP 2010513478A5 JP 2009542710 A JP2009542710 A JP 2009542710A JP 2009542710 A JP2009542710 A JP 2009542710A JP 2010513478 A5 JP2010513478 A5 JP 2010513478A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound
- indazol
- copd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87118406P | 2006-12-21 | 2006-12-21 | |
| US60/871,184 | 2006-12-21 | ||
| US94174507P | 2007-06-04 | 2007-06-04 | |
| US60/941,745 | 2007-06-04 | ||
| US97852607P | 2007-10-09 | 2007-10-09 | |
| US60/978,526 | 2007-10-09 | ||
| PCT/SE2007/001136 WO2008076048A1 (en) | 2006-12-21 | 2007-12-20 | Indazolyl ester and amide derivatives for the treatment of glucocorticoid receptor mediated disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012184346A Division JP2012224647A (ja) | 2006-12-21 | 2012-08-23 | グルココルチコイド受容体介在障害の処置のためのインダゾリルエステルおよびアミド誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010513478A JP2010513478A (ja) | 2010-04-30 |
| JP2010513478A5 true JP2010513478A5 (https=) | 2012-10-11 |
| JP5119267B2 JP5119267B2 (ja) | 2013-01-16 |
Family
ID=39536557
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009542710A Expired - Fee Related JP5119267B2 (ja) | 2006-12-21 | 2007-12-20 | グルココルチコイド受容体介在障害の処置のためのインダゾリルエステルおよびアミド誘導体 |
| JP2012184346A Pending JP2012224647A (ja) | 2006-12-21 | 2012-08-23 | グルココルチコイド受容体介在障害の処置のためのインダゾリルエステルおよびアミド誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012184346A Pending JP2012224647A (ja) | 2006-12-21 | 2012-08-23 | グルココルチコイド受容体介在障害の処置のためのインダゾリルエステルおよびアミド誘導体 |
Country Status (36)
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH081035Y2 (ja) | 1993-06-30 | 1996-01-17 | 伸夫 高橋 | 家庭用雑排水の処理装置 |
| FR2866886B1 (fr) * | 2004-02-26 | 2007-08-31 | Sanofi Synthelabo | Derives d'aryl-et d'heteroaryl-akylcarbamates, leur preparation et leur application en therapeutique |
| TW200829578A (en) | 2006-11-23 | 2008-07-16 | Astrazeneca Ab | Chemical compounds 537 |
| JO2754B1 (en) | 2006-12-21 | 2014-03-15 | استرازينكا ايه بي | Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders |
| WO2009142589A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
| UY31832A (es) | 2008-05-20 | 2010-01-05 | Astrazeneca Ab | Derivados de indazol sustituidos con fenilo y benzodioxinilo |
| WO2009142588A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) a chemokine receptor 1 (ccr1) antagonist and (b) glucocorticoid receptor modulator |
| WO2009142568A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) glucocorticoid receptor modulator and (b) a b2-agonist |
| WO2010008341A1 (en) * | 2008-07-16 | 2010-01-21 | Astrazeneca Ab | A combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
| WO2010138421A1 (en) * | 2009-05-27 | 2010-12-02 | Merck Sharp & Dohme Corp. | HEXAHYDROCYCLOPENTYL[f]INDAZOLE REVERSED AMIDES AND DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS |
| US9284301B2 (en) | 2010-03-25 | 2016-03-15 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
| GB201016912D0 (en) | 2010-10-07 | 2010-11-24 | Astrazeneca Ab | Novel combination |
| GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
| GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
| EP2726464A1 (en) | 2011-06-29 | 2014-05-07 | Astrazeneca AB | Crystalline form of indazolyl amide derivatives for the treatment glucocorticoid receptor mediated disorders |
| CA2926095A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| CA2925953C (en) | 2013-10-17 | 2021-11-02 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| US9029554B1 (en) | 2013-10-17 | 2015-05-12 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| MX2016004941A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Proceso para la preparacion de compuestos plaguicidas. |
| JP2016539092A (ja) | 2013-10-17 | 2016-12-15 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除性化合物の製造方法 |
| EP3057429A4 (en) | 2013-10-17 | 2017-08-09 | Dow AgroSciences LLC | Processes for the preparation of pesticidal compounds |
| CA2925952A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| JP2017523168A (ja) | 2014-07-31 | 2017-08-17 | ダウ アグロサイエンシィズ エルエルシー | ３−（３−クロロ−１ｈ−ピラゾール−１−イル）ピリジンの製造方法 |
| BR112017000293A2 (pt) | 2014-07-31 | 2017-10-31 | Dow Agrosciences Llc | processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina |
| US9249122B1 (en) | 2014-07-31 | 2016-02-02 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
| JP2017525703A (ja) | 2014-08-19 | 2017-09-07 | ダウ アグロサイエンシィズ エルエルシー | ３−（３−クロロ−１ｈ−ピラゾール−１−イル）ピリジンの調製方法 |
| AR098113A1 (es) | 2014-09-12 | 2016-05-04 | Dow Agrosciences Llc | Proceso para la preparación de 3-(3-cloro-1h-pirazol-1-il)piridina |
| FR3026105B1 (fr) * | 2014-09-24 | 2019-04-19 | Greenpharma | Composition contenant au moins un inhibiteur de certaines chimiokines, son procede d'obtention et son utilisation dermocosmetique ou pharmaceutique |
| NZ730250A (en) * | 2014-09-26 | 2018-03-23 | Astrazeneca Ab | 1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as sgrm modulators |
| HRP20200130T1 (hr) | 2015-09-15 | 2020-05-15 | Leo Pharma A/S | Ne-steroidni modulatori glukokortikoidnog receptora za lokalni unos lijeka |
| WO2017161518A1 (en) | 2016-03-23 | 2017-09-28 | Astrazeneca Ab | New physical form |
| JP2020503336A (ja) | 2016-12-29 | 2020-01-30 | ダウ アグロサイエンシィズ エルエルシー | 殺有害生物化合物の調製方法 |
| CN110325036B (zh) | 2016-12-29 | 2021-10-26 | 美国陶氏益农公司 | 用于制备杀虫化合物的方法 |
| AR113967A1 (es) | 2017-12-18 | 2020-07-01 | Gruenenthal Gmbh | Pirrolidinamidas i sustituidas |
| TW201927769A (zh) * | 2017-12-18 | 2019-07-16 | 德商歌林達有限公司 | 經取代之吡咯啶醯胺ｉｉ |
| JP7446316B2 (ja) | 2019-01-11 | 2024-03-08 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 置換ピロリジンアミドｉｉｉ |
| ES2980934T3 (es) | 2019-01-22 | 2024-10-03 | Akribes Biomedical Gmbh | Modificadores selectivos del receptor de glucocorticoides para tratar la cicatrización alterada de heridas en la piel |
| EP3986885B1 (en) | 2019-06-19 | 2023-05-03 | Grünenthal GmbH | Substituted pyrrolidine amides iv |
| EP3986886A2 (en) | 2019-06-19 | 2022-04-27 | Grünenthal GmbH | Substituted pyrrolidine amides v |
| EP4086247A4 (en) * | 2019-12-31 | 2023-12-06 | Medshine Discovery Inc. | BENZOPYRAZOLE COMPOUND |
| WO2022008705A1 (en) | 2020-07-09 | 2022-01-13 | Grünenthal GmbH | Substituted pyrrolidine amines and amides as mediator of the glucocortoid receptor |
| US20240246985A1 (en) * | 2021-06-28 | 2024-07-25 | Medshine Discovery Inc. | Crystal form of triazolopyridine-substituted indazole compound and preparation method therefor |
| KR102571432B1 (ko) * | 2023-02-08 | 2023-08-29 | 주식회사 에스씨엘테라퓨틱스 | 인다졸릴에스테르 및 아미드 유도체를 포함하는 암 치료용 조성물 |
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| DE3535167A1 (de) | 1985-10-02 | 1987-04-09 | Boehringer Mannheim Gmbh | Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3632329A1 (de) | 1986-09-24 | 1988-03-31 | Bayer Ag | Substituierte phenylsulfonamide |
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| EA200970401A1 (ru) | 2006-10-23 | 2009-10-30 | Мерк Энд Ко., Инк. | 2-[1-ФЕНИЛ-5-ГИДРОКСИ ИЛИ МЕТОКСИ-4-АЛЬФА-МЕТИЛГЕКСАГИДРОЦИКЛОПЕНТА[f]ИНДАЗОЛ-5-ИЛ] ЭТИЛФЕНИЛЬНЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ ЛИГАНДОВ ГЛЮКОКОРТИКОИДНОГО РЕЦЕПТОРА |
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| EP2102170A2 (en) | 2006-12-06 | 2009-09-23 | Boehringer Ingelheim International GmbH | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| JO2754B1 (en) | 2006-12-21 | 2014-03-15 | استرازينكا ايه بي | Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders |
| WO2008079073A1 (en) | 2006-12-22 | 2008-07-03 | Astrazeneca Ab | Indazolyl sulphonamide derivatives for the treatment of glucocorticoid receptor mediated disorders |
| CA2683647A1 (en) | 2007-04-10 | 2008-10-16 | Boehringer Ingelheim International Gmbh | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
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| GB0708858D0 (en) | 2007-05-08 | 2007-06-13 | Glaxo Group Ltd | Novel compounds |
| GB0720544D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
| GB0720556D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
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| GB0720557D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
| GB0720546D0 (en) | 2007-10-19 | 2007-11-28 | Glaxo Group Ltd | Novel compounds |
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| UY31832A (es) | 2008-05-20 | 2010-01-05 | Astrazeneca Ab | Derivados de indazol sustituidos con fenilo y benzodioxinilo |
| WO2010008341A1 (en) * | 2008-07-16 | 2010-01-21 | Astrazeneca Ab | A combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
-
2007
- 2007-12-17 JO JO2007553A patent/JO2754B1/en active
- 2007-12-20 MX MX2009006540A patent/MX2009006540A/es active IP Right Grant
- 2007-12-20 NZ NZ577186A patent/NZ577186A/en not_active IP Right Cessation
- 2007-12-20 PT PT07852132T patent/PT2102169E/pt unknown
- 2007-12-20 EP EP07852132A patent/EP2102169B1/en active Active
- 2007-12-20 DK DK07852132.5T patent/DK2102169T3/da active
- 2007-12-20 EA EA200900658A patent/EA016895B1/ru not_active IP Right Cessation
- 2007-12-20 TW TW096148902A patent/TWI417094B/zh not_active IP Right Cessation
- 2007-12-20 CA CA002673277A patent/CA2673277A1/en not_active Abandoned
- 2007-12-20 MY MYPI20092610A patent/MY153270A/en unknown
- 2007-12-20 HR HRP20120656TT patent/HRP20120656T1/hr unknown
- 2007-12-20 JP JP2009542710A patent/JP5119267B2/ja not_active Expired - Fee Related
- 2007-12-20 CN CN200780051662XA patent/CN101611015B/zh not_active Expired - Fee Related
- 2007-12-20 AU AU2007334659A patent/AU2007334659B2/en not_active Ceased
- 2007-12-20 WO PCT/SE2007/001136 patent/WO2008076048A1/en not_active Ceased
- 2007-12-20 US US12/005,066 patent/US7728030B2/en not_active Expired - Fee Related
- 2007-12-20 ES ES07852132T patent/ES2387584T3/es active Active
- 2007-12-20 RS RS20120358A patent/RS52411B/sr unknown
- 2007-12-20 KR KR1020097015234A patent/KR20090091354A/ko not_active Ceased
- 2007-12-20 UY UY30824A patent/UY30824A1/es not_active Application Discontinuation
- 2007-12-20 PL PL07852132T patent/PL2102169T3/pl unknown
- 2007-12-21 AR ARP070105870A patent/AR064505A1/es not_active Application Discontinuation
- 2007-12-21 CL CL200703804A patent/CL2007003804A1/es unknown
- 2007-12-29 SA SA7280740A patent/SA07280740B1/ar unknown
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2008
- 2008-01-02 PE PE2008000011A patent/PE20081838A1/es not_active Application Discontinuation
-
2009
- 2009-05-21 IL IL198880A patent/IL198880A/en not_active IP Right Cessation
- 2009-05-26 ZA ZA2009/03654A patent/ZA200903654B/en unknown
- 2009-06-19 DO DO2009000148A patent/DOP2009000148A/es unknown
- 2009-06-19 GT GT200900175A patent/GT200900175A/es unknown
- 2009-06-19 TN TNP2009000250A patent/TN2009000250A1/fr unknown
- 2009-06-19 SV SV2009003305A patent/SV2009003305A/es active IP Right Grant
- 2009-06-19 CR CR10875A patent/CR10875A/es unknown
- 2009-06-23 EC EC2009009452A patent/ECSP099452A/es unknown
- 2009-07-09 MA MA32078A patent/MA31087B1/fr unknown
- 2009-07-17 NO NO20092723A patent/NO20092723L/no not_active Application Discontinuation
- 2009-12-21 US US12/643,504 patent/US20100197644A1/en not_active Abandoned
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2010
- 2010-12-02 US US12/959,027 patent/US8143290B2/en not_active Expired - Fee Related
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2012
- 2012-03-23 US US13/429,177 patent/US20120252770A1/en not_active Abandoned
- 2012-08-13 CY CY20121100730T patent/CY1113269T1/el unknown
- 2012-08-23 JP JP2012184346A patent/JP2012224647A/ja active Pending