JP2010504957A5 - - Google Patents

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Publication number
JP2010504957A5
JP2010504957A5 JP2009529841A JP2009529841A JP2010504957A5 JP 2010504957 A5 JP2010504957 A5 JP 2010504957A5 JP 2009529841 A JP2009529841 A JP 2009529841A JP 2009529841 A JP2009529841 A JP 2009529841A JP 2010504957 A5 JP2010504957 A5 JP 2010504957A5
Authority
JP
Japan
Prior art keywords
aza
bicyclo
hex
thiazole
ylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2009529841A
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English (en)
Japanese (ja)
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JP2010504957A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2007/053947 external-priority patent/WO2008038251A2/en
Publication of JP2010504957A publication Critical patent/JP2010504957A/ja
Publication of JP2010504957A5 publication Critical patent/JP2010504957A5/ja
Ceased legal-status Critical Current

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JP2009529841A 2006-09-29 2007-09-28 3−アザ−ビシクロ[3.1.0]ヘキサン誘導体 Ceased JP2010504957A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006053570 2006-09-29
PCT/IB2007/053947 WO2008038251A2 (en) 2006-09-29 2007-09-28 3-aza-bicyclo[3.1.0]hexane derivatives

Publications (2)

Publication Number Publication Date
JP2010504957A JP2010504957A (ja) 2010-02-18
JP2010504957A5 true JP2010504957A5 (OSRAM) 2013-03-28

Family

ID=39106344

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009529841A Ceased JP2010504957A (ja) 2006-09-29 2007-09-28 3−アザ−ビシクロ[3.1.0]ヘキサン誘導体

Country Status (13)

Country Link
US (1) US20100016401A1 (OSRAM)
EP (1) EP2079690B1 (OSRAM)
JP (1) JP2010504957A (OSRAM)
KR (1) KR20090077051A (OSRAM)
CN (1) CN101522618A (OSRAM)
AR (1) AR063081A1 (OSRAM)
AT (1) ATE481383T1 (OSRAM)
CA (1) CA2662612A1 (OSRAM)
CL (1) CL2007002809A1 (OSRAM)
DE (1) DE602007009284D1 (OSRAM)
ES (1) ES2350460T3 (OSRAM)
TW (1) TW200823227A (OSRAM)
WO (1) WO2008038251A2 (OSRAM)

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BR112012010752B1 (pt) * 2009-11-05 2021-07-20 University Of Notre Dame Du Lac Compostos imidazo[1,2-a]piridina
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UA119151C2 (uk) 2013-12-03 2019-05-10 Ідорсія Фармасьютікалз Лтд КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА
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JP7055378B2 (ja) 2015-09-17 2022-04-18 ユニバーシティ・オブ・ノートル・ダム・デュ・ラック マイコバクテリア感染症に対して有用なベンジルアミン含有複素環化合物及び組成物
TWI710557B (zh) 2016-02-12 2020-11-21 美商伊歐拉斯治療學公司 作為食慾素受體調節劑之經鹵素取代之六氫吡啶
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WO2017194548A1 (en) 2016-05-10 2017-11-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of autoimmune inflammatory diseases
PT3619199T (pt) 2017-05-03 2021-10-01 Idorsia Pharmaceuticals Ltd Preparação de derivados de ácido 2-([1,2,3]triazol-2-il)- benzoico
WO2020007964A1 (en) 2018-07-05 2020-01-09 Idorsia Pharmaceuticals Ltd 2-(2-azabicyclo[3.1.0]hexan-1-yl)-1h-benzimidazole derivatives
WO2020007977A1 (en) 2018-07-06 2020-01-09 Idorsia Pharmaceuticals Ltd 7-trifluoromethyl-[1,4]diazepan derivatives
WO2020099511A1 (en) 2018-11-14 2020-05-22 Idorsia Pharmaceuticals Ltd Benzimidazole-2-methyl-morpholine derivatives
CN116783182B (zh) * 2021-02-02 2025-08-29 南京明德新药研发有限公司 四氢吡咯并环化合物及其应用
TW202400149A (zh) 2022-05-13 2024-01-01 瑞士商愛杜西亞製藥有限公司 經噻唑并芳基-甲基取代之環狀肼-n-甲醯胺衍生物
CN117126101A (zh) * 2023-08-28 2023-11-28 瑞博(杭州)医药科技有限公司 一种脯氨酸结构的盐酸盐中间体的高效制备方法
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AU2008257411B2 (en) * 2007-05-23 2012-04-26 Merck Sharp & Dohme Corp. Pyridyl piperidine orexin receptor antagonists
US8106215B2 (en) * 2007-07-03 2012-01-31 Actelion Pharmaceuticals Ltd. 3-aza-bicyclo[3.3.0]octane compounds
AR067665A1 (es) * 2007-07-27 2009-10-21 Actelion Pharmaceuticals Ltd Derivados de trans-3- aza-biciclo ( 3.1.0) hexano
WO2009016560A2 (en) * 2007-07-27 2009-02-05 Actelion Pharmaceuticals Ltd Trans-3-aza-bicyclo[3.1.0]hexane derivatives
US8288429B2 (en) * 2007-07-27 2012-10-16 Actelion Pharmaceuticals Ltd. 2-aza-bicyclo[3.3.0]octane derivatives
US8288411B2 (en) * 2007-09-24 2012-10-16 Actelion Pharmaceuticals Ltd. Pyrrolidines and piperidines as orexin receptor antagonists
WO2009104155A1 (en) * 2008-02-21 2009-08-27 Actelion Pharmaceuticals Ltd 2-aza-bicyclo[2.2.1]heptane derivatives
JP2011519849A (ja) * 2008-04-30 2011-07-14 アクテリオン ファーマシューティカルズ リミテッド ピペリジン及びピロリジン化合物

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