JP2010142240A5 - - Google Patents
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- Publication number
- JP2010142240A5 JP2010142240A5 JP2010019881A JP2010019881A JP2010142240A5 JP 2010142240 A5 JP2010142240 A5 JP 2010142240A5 JP 2010019881 A JP2010019881 A JP 2010019881A JP 2010019881 A JP2010019881 A JP 2010019881A JP 2010142240 A5 JP2010142240 A5 JP 2010142240A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- sequence
- protein
- traustochytriales
- microorganism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims 28
- 108090000623 proteins and genes Proteins 0.000 claims 24
- 150000007523 nucleic acids Chemical class 0.000 claims 17
- 102000004169 proteins and genes Human genes 0.000 claims 16
- 244000005700 microbiome Species 0.000 claims 12
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 claims 12
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 5
- 230000000813 microbial effect Effects 0.000 claims 5
- 108010030975 Polyketide Synthases Proteins 0.000 claims 4
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 235000014113 dietary fatty acids Nutrition 0.000 claims 3
- 229930195729 fatty acid Natural products 0.000 claims 3
- 239000000194 fatty acid Substances 0.000 claims 3
- 238000003786 synthesis reaction Methods 0.000 claims 3
- 102000009114 Fatty acid desaturases Human genes 0.000 claims 2
- 108010087894 Fatty acid desaturases Proteins 0.000 claims 2
- 108700028146 Genetic Enhancer Elements Proteins 0.000 claims 2
- 102000004243 Tubulin Human genes 0.000 claims 2
- 108090000704 Tubulin Proteins 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 230000006801 homologous recombination Effects 0.000 claims 2
- 238000002744 homologous recombination Methods 0.000 claims 2
- 230000000415 inactivating effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- 230000014616 translation Effects 0.000 claims 2
- 241000003595 Aurantiochytrium limacinum Species 0.000 claims 1
- 239000002028 Biomass Substances 0.000 claims 1
- 102000004882 Lipase Human genes 0.000 claims 1
- 108090001060 Lipase Proteins 0.000 claims 1
- 239000004367 Lipase Substances 0.000 claims 1
- 102000004316 Oxidoreductases Human genes 0.000 claims 1
- 108090000854 Oxidoreductases Proteins 0.000 claims 1
- 241000233671 Schizochytrium Species 0.000 claims 1
- 241000233673 Schizochytrium aggregatum Species 0.000 claims 1
- 241000598397 Schizochytrium sp. Species 0.000 claims 1
- 229930182558 Sterol Natural products 0.000 claims 1
- 235000021466 carotenoid Nutrition 0.000 claims 1
- 150000001747 carotenoids Chemical class 0.000 claims 1
- 210000002421 cell wall Anatomy 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 235000019421 lipase Nutrition 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 230000037361 pathway Effects 0.000 claims 1
- 150000003432 sterols Chemical class 0.000 claims 1
- 235000003702 sterols Nutrition 0.000 claims 1
- 150000003505 terpenes Chemical class 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28411601P | 2001-04-16 | 2001-04-16 | |
| US60/284,116 | 2001-04-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582208A Division JP4536324B2 (ja) | 2001-04-16 | 2002-04-16 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012215905A Division JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010142240A JP2010142240A (ja) | 2010-07-01 |
| JP2010142240A5 true JP2010142240A5 (https=) | 2011-04-14 |
| JP5248536B2 JP5248536B2 (ja) | 2013-07-31 |
Family
ID=23088908
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582208A Expired - Fee Related JP4536324B2 (ja) | 2001-04-16 | 2002-04-16 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2010019881A Expired - Lifetime JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2012215905A Withdrawn JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2015253726A Expired - Fee Related JP6211577B2 (ja) | 2001-04-16 | 2015-12-25 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582208A Expired - Fee Related JP4536324B2 (ja) | 2001-04-16 | 2002-04-16 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012215905A Withdrawn JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2015253726A Expired - Fee Related JP6211577B2 (ja) | 2001-04-16 | 2015-12-25 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7001772B2 (https=) |
| EP (3) | EP2325319B1 (https=) |
| JP (4) | JP4536324B2 (https=) |
| CN (3) | CN101760469A (https=) |
| AT (1) | ATE533844T1 (https=) |
| AU (1) | AU2002250592C1 (https=) |
| CA (1) | CA2443908C (https=) |
| ES (3) | ES2377557T3 (https=) |
| TW (3) | TWI377253B (https=) |
| WO (1) | WO2002083869A2 (https=) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US8003772B2 (en) * | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| TWI377253B (en) * | 2001-04-16 | 2012-11-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7211656B2 (en) * | 2002-01-30 | 2007-05-01 | Abbott Laboratories | Desaturase genes, enzymes encoded thereby, and uses thereof |
| ATE354645T1 (de) * | 2002-12-20 | 2007-03-15 | Chromagenics Bv | Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können |
| US7208590B2 (en) * | 2003-07-15 | 2007-04-24 | Abbott Laboratories | Genes involved in polyketide synthase pathways and uses thereof |
| CN103451246B (zh) | 2004-04-22 | 2018-02-16 | 联邦科学技术研究组织 | 用重组细胞合成长链多不饱和脂肪酸 |
| EP2357244A3 (en) | 2004-04-22 | 2011-11-23 | Commonwealth Scientific and Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells. |
| EP1809750B1 (en) * | 2004-11-08 | 2012-03-21 | ChromaGenics B.V. | Selection of host cells expressing protein at high levels |
| US8999667B2 (en) * | 2004-11-08 | 2015-04-07 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20060195935A1 (en) | 2004-11-08 | 2006-08-31 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20100136616A1 (en) * | 2004-11-08 | 2010-06-03 | Chromagenics B.V. | Selection of Host Cells Expressing Protein at High Levels |
| US20060172382A1 (en) * | 2004-11-08 | 2006-08-03 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| JP4796787B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
| JP4796786B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
| AU2006325040B2 (en) | 2005-06-07 | 2012-04-19 | Dsm Nutritional Products Ag | Eukaryotic microorganisms for producing lipids and antioxidants |
| AU2006316610B2 (en) | 2005-11-23 | 2012-06-14 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| EP1818411A1 (en) * | 2006-02-13 | 2007-08-15 | Lonza AG | Process for the preparation of optically active chiral amines |
| WO2007106905A2 (en) * | 2006-03-15 | 2007-09-20 | Martek Biosciences Corporation | Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems |
| KR20090007407A (ko) * | 2006-04-11 | 2009-01-16 | 마텍 바이오싸이언스스 코포레이션 | 장쇄 다중불포화 지방산을 포함하는 식품 제품 및 그의 제조 방법 |
| EP2034973B2 (en) | 2006-06-22 | 2022-01-19 | DSM IP Assets B.V. | Encapsulated labile compound compositions and methods of making the same |
| CA2659603C (en) * | 2006-08-01 | 2017-03-07 | Ocean Nutrition Canada Limited | Oil producing microbes and methods of modification thereof |
| RU2009111266A (ru) | 2006-08-29 | 2010-10-10 | Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) | Синтез жирных кислот |
| EP2415360A3 (en) | 2006-08-29 | 2012-02-29 | Martek Biosciences Corporation | Use of DPA(n-6) oils in infant formula |
| KR100860111B1 (ko) * | 2006-10-02 | 2008-09-25 | 인제대학교 산학협력단 | 신규 미생물 트라우스토카이트리움 에스피.케이제이에스-1, 바실러스 폴리퍼멘티쿠스 케이제이에스-2 및 이들과 바실러스 리케니포르미스를 포함하고 있는 사료첨가제 및 사료 |
| EP2082050B1 (en) | 2006-10-23 | 2013-04-24 | E.I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
| US8188338B2 (en) | 2007-04-10 | 2012-05-29 | E. I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
| US8119860B2 (en) | 2007-04-16 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| US8957280B2 (en) | 2007-05-03 | 2015-02-17 | E. I. Du Pont De Nemours And Company | Delta-5 desaturases and their use in making polyunsaturated fatty acids |
| AU2008269989B2 (en) * | 2007-06-29 | 2014-02-27 | Dsm Ip Assets B.V. | Production and purification of esters of polyunsaturated fatty acids |
| US20090064567A1 (en) | 2007-09-12 | 2009-03-12 | Martek Biosciences Corporation | Biological oils and production and uses Thereof |
| US20110076379A1 (en) * | 2008-06-13 | 2011-03-31 | Means Michael M | High omega saturated fat free meat products |
| BRPI0921467B1 (pt) | 2008-11-18 | 2021-12-14 | Commonwealth Scientific And Industrial Research Organisation | Processo para a produção de óleo compreendendo ácido eicosapentaenóico (epa), ácido docosapentaenóico (dpa) e ácido docosahexaenóico (dha) |
| AU2009335903B2 (en) | 2008-12-18 | 2016-04-14 | E. I. Du Pont De Nemours And Company | Reducing byproduction of malonates in a fermentation process |
| JP5415896B2 (ja) | 2009-01-29 | 2014-02-12 | Jfeスチール株式会社 | インダイレクトスポット溶接方法 |
| ES2752196T3 (es) * | 2009-03-16 | 2020-04-03 | Dsm Ip Assets Bv | Producción de proteínas en microorganismos del filo Labyrinthulomycota |
| US8207363B2 (en) | 2009-03-19 | 2012-06-26 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| US8940884B2 (en) | 2009-03-19 | 2015-01-27 | Dsm Ip Assets B.V. | Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof |
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| WO2011037207A1 (ja) * | 2009-09-24 | 2011-03-31 | 国立大学法人九州大学 | ストラメノパイルの形質転換方法 |
| CN103068965A (zh) | 2009-12-28 | 2013-04-24 | Dsmip资产公司 | 在蔗糖上生长的重组破囊壶菌和其组合物、制备方法及用途 |
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| KR20140008295A (ko) | 2010-08-26 | 2014-01-21 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 돌연변이 델타-9 연장효소 및 다중불포화 지방산의 제조에서의 그들의 용도 |
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-
2002
- 2002-04-15 TW TW100112656A patent/TWI377253B/zh not_active IP Right Cessation
- 2002-04-15 TW TW091107634A patent/TWI324181B/zh not_active IP Right Cessation
- 2002-04-15 TW TW098130758A patent/TWI350854B/zh not_active IP Right Cessation
- 2002-04-16 CN CN200910141898A patent/CN101760469A/zh active Pending
- 2002-04-16 AU AU2002250592A patent/AU2002250592C1/en not_active Ceased
- 2002-04-16 EP EP10178886.7A patent/EP2325319B1/en not_active Expired - Lifetime
- 2002-04-16 US US10/124,807 patent/US7001772B2/en not_active Expired - Lifetime
- 2002-04-16 ES ES02719515T patent/ES2377557T3/es not_active Expired - Lifetime
- 2002-04-16 CN CNB2006100842683A patent/CN100513564C/zh not_active Expired - Fee Related
- 2002-04-16 ES ES10178886.7T patent/ES2688953T3/es not_active Expired - Lifetime
- 2002-04-16 EP EP02719515A patent/EP1414941B1/en not_active Expired - Lifetime
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- 2002-04-16 WO PCT/US2002/012040 patent/WO2002083869A2/en not_active Ceased
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- 2002-04-16 EP EP10178911.3A patent/EP2314706B1/en not_active Expired - Lifetime
- 2002-04-16 AT AT02719515T patent/ATE533844T1/de active
- 2002-04-16 CN CN028120590A patent/CN1556850B/zh not_active Expired - Fee Related
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2004
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- 2007-10-27 US US11/925,885 patent/US7851191B2/en not_active Expired - Fee Related
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2010
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- 2010-11-09 US US12/942,759 patent/US20110086390A1/en not_active Abandoned
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2012
- 2012-09-28 JP JP2012215905A patent/JP2013005817A/ja not_active Withdrawn
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2013
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