JP2009528303A5 - - Google Patents

Info

Publication number

JP2009528303A5

JP2009528303A5 JP2008556643A JP2008556643A JP2009528303A5 JP 2009528303 A5 JP2009528303 A5 JP 2009528303A5 JP 2008556643 A JP2008556643 A JP 2008556643A JP 2008556643 A JP2008556643 A JP 2008556643A JP 2009528303 A5 JP2009528303 A5 JP 2009528303A5

Authority

JP

Japan

Prior art keywords

compound

amino acid

pharmaceutically acceptable

acceptable salt

pharmaceutical composition

Prior art date

2007-02-28

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 150000001875 compounds Chemical class 0.000 claims 17
• 150000001413 amino acids Chemical class 0.000 claims 6
• 150000003839 salts Chemical class 0.000 claims 6
• 239000000126 substance Substances 0.000 claims 6
• 241001465754 Metazoa Species 0.000 claims 5
• 239000008194 pharmaceutical composition Substances 0.000 claims 5
• 150000008575 L-amino acids Chemical group 0.000 claims 3
• 239000000203 mixture Substances 0.000 claims 3
• 108090000765 processed proteins & peptides Proteins 0.000 claims 3
• 241000251468 Actinopterygii Species 0.000 claims 2
• 241000238424 Crustacea Species 0.000 claims 2
• 208000035240 Disease Resistance Diseases 0.000 claims 2
• BGHSOEHUOOAYMY-JTZMCQEISA-N ghrelin Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)CN)C1=CC=CC=C1 BGHSOEHUOOAYMY-JTZMCQEISA-N 0.000 claims 2
• 230000006698 induction Effects 0.000 claims 2
• 238000002347 injection Methods 0.000 claims 2
• 239000007924 injection Substances 0.000 claims 2
• 239000000546 pharmaceutical excipient Substances 0.000 claims 2
• 101800001586 Ghrelin Proteins 0.000 claims 1
• 102000012004 Ghrelin Human genes 0.000 claims 1
• 102000018997 Growth Hormone Human genes 0.000 claims 1
• 108010051696 Growth Hormone Proteins 0.000 claims 1
• 235000021407 appetite control Nutrition 0.000 claims 1
• 238000009360 aquaculture Methods 0.000 claims 1
• 244000144974 aquaculture Species 0.000 claims 1
• 230000037396 body weight Effects 0.000 claims 1
• 230000005961 cardioprotection Effects 0.000 claims 1
• 238000006243 chemical reaction Methods 0.000 claims 1
• 108010051768 des-n-octanoyl ghrelin Proteins 0.000 claims 1
• 235000015872 dietary supplement Nutrition 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 230000037149 energy metabolism Effects 0.000 claims 1
• 239000000122 growth hormone Substances 0.000 claims 1
• 239000003324 growth hormone secretagogue Substances 0.000 claims 1
• 238000007654 immersion Methods 0.000 claims 1
• 230000001939 inductive effect Effects 0.000 claims 1
• 239000008176 lyophilized powder Substances 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 230000004060 metabolic process Effects 0.000 claims 1
• 230000004112 neuroprotection Effects 0.000 claims 1
• 238000007363 ring formation reaction Methods 0.000 claims 1
• 238000002791 soaking Methods 0.000 claims 1
• 239000000243 solution Substances 0.000 claims 1
• 230000004936 stimulating effect Effects 0.000 claims 1
• 230000000638 stimulation Effects 0.000 claims 1