JP2009501333A5 - - Google Patents
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- JP2009501333A5 JP2009501333A5 JP2008520966A JP2008520966A JP2009501333A5 JP 2009501333 A5 JP2009501333 A5 JP 2009501333A5 JP 2008520966 A JP2008520966 A JP 2008520966A JP 2008520966 A JP2008520966 A JP 2008520966A JP 2009501333 A5 JP2009501333 A5 JP 2009501333A5
- Authority
- JP
- Japan
- Prior art keywords
- gstp
- stroke
- level
- subject
- diagnosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000005720 Glutathione transferase Human genes 0.000 claims 13
- 108010070675 Glutathione transferase Proteins 0.000 claims 13
- 238000000034 method Methods 0.000 claims 12
- 208000006011 Stroke Diseases 0.000 claims 9
- 102000001708 Protein Isoforms Human genes 0.000 claims 4
- 108010029485 Protein Isoforms Proteins 0.000 claims 4
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 3
- 238000003745 diagnosis Methods 0.000 claims 3
- 230000004481 post-translational protein modification Effects 0.000 claims 3
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 238000005259 measurement Methods 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 238000002965 ELISA Methods 0.000 claims 1
- 230000004988 N-glycosylation Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 230000006641 stabilisation Effects 0.000 claims 1
- 238000011105 stabilization Methods 0.000 claims 1
- 210000001138 tear Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0514435A GB2428240A (en) | 2005-07-14 | 2005-07-14 | Diagnostic method for brain damage-related disorders |
| GB0514435.7 | 2005-07-14 | ||
| PCT/GB2006/050207 WO2007007129A2 (en) | 2005-07-14 | 2006-07-14 | Diagnostic method for brain damage-related disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013011339A Division JP2013092538A (ja) | 2005-07-14 | 2013-01-24 | 脳損傷関連障害の診断法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009501333A JP2009501333A (ja) | 2009-01-15 |
| JP2009501333A5 true JP2009501333A5 (enExample) | 2009-06-18 |
| JP5281397B2 JP5281397B2 (ja) | 2013-09-04 |
Family
ID=34897198
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008520966A Active JP5281397B2 (ja) | 2005-07-14 | 2006-07-14 | 脳損傷関連障害の診断法 |
| JP2013011339A Pending JP2013092538A (ja) | 2005-07-14 | 2013-01-24 | 脳損傷関連障害の診断法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013011339A Pending JP2013092538A (ja) | 2005-07-14 | 2013-01-24 | 脳損傷関連障害の診断法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9028825B2 (enExample) |
| EP (1) | EP1902319B1 (enExample) |
| JP (2) | JP5281397B2 (enExample) |
| AT (1) | ATE456055T1 (enExample) |
| AU (1) | AU2006268034B2 (enExample) |
| CA (1) | CA2613991C (enExample) |
| DE (1) | DE602006011896D1 (enExample) |
| ES (1) | ES2336946T3 (enExample) |
| GB (1) | GB2428240A (enExample) |
| WO (1) | WO2007007129A2 (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9929140D0 (en) * | 1999-12-10 | 2000-02-02 | Univ Geneve | Diagnostic assay for stroke |
| US8492107B2 (en) | 2004-04-15 | 2013-07-23 | University Of Florida Research Foundation, Inc. | Neural proteins as biomarkers for nervous system injury and other neural disorders |
| AU2007247742B2 (en) | 2006-05-09 | 2013-06-06 | The University Of British Columbia | Dissolved protein arthritis markers |
| DE102006048201A1 (de) * | 2006-10-11 | 2008-04-17 | Ganymed Pharmaceuticals Ag | Autoantigene zur verbesserten Diagnose, Prognose und Therapie von entzündlichen neurologischen Erkrankungen |
| US20090104639A1 (en) * | 2007-09-12 | 2009-04-23 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomarkers for motor neuron disease |
| KR20180102215A (ko) | 2007-11-27 | 2018-09-14 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 관절염의 진단과 치료를 위한 14-3-3 에타 항체 및 이의 용도 |
| CA2878025C (en) | 2008-01-18 | 2018-12-11 | President And Fellows Of Harvard College | Methods of detecting signatures of disease or conditions in bodily fluids |
| EP2277049A4 (en) * | 2008-05-09 | 2012-05-30 | Univ Duke | AUTOANTIKÖRPER FOR THE PROOF AND THE TREATMENT OF CANCER |
| JP5781436B2 (ja) | 2008-08-11 | 2015-09-24 | バンヤン・バイオマーカーズ・インコーポレーテッド | 神経学的状態のバイオマーカー検出方法およびアッセイ |
| DK2389587T3 (en) * | 2009-01-26 | 2014-03-03 | Electrophoretics Ltd | Diagnostic and prognostic methods related Alzheimer's Disease |
| AU2009339152B2 (en) * | 2009-01-30 | 2015-11-19 | Bio-Rad Europe Gmbh | Method for the in vitro diagnosis of stroke |
| CA2754741C (en) | 2009-03-11 | 2019-02-12 | Augurex Life Sciences Corporation | Compositions and methods for characterizing arthritic conditions |
| CA2807645C (en) * | 2009-08-07 | 2021-09-07 | Affinimark Technologies, Inc. | Device and methods for the immunological identification of cerebrospinal fluid |
| HUE040281T2 (hu) * | 2009-09-14 | 2019-03-28 | Banyan Biomarkers Inc | Autoantitest markerek traumás agysérülés diagnózisára |
| RU2422095C1 (ru) * | 2009-12-11 | 2011-06-27 | Федеральное государственное учреждение "Ростовский научно-исследовательский онкологический институт Федерального агентства по высокотехнологичной медицинской помощи" | Способ прогнозирования эффективности местной химиотерапии при лечении больных злокачественными опухолями головного мозга |
| WO2011106322A2 (en) * | 2010-02-23 | 2011-09-01 | The Govt. Of The U.S.A. As Represented By The Secretary, Department Of Health And Human Services. | Biomarkers for acute ischemic stroke |
| GB201008541D0 (en) * | 2010-05-21 | 2010-07-07 | Univ Geneve | Diagnostic methods |
| WO2012012717A1 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting prenatal or pregnancy-related diseases or conditions |
| AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
| MX2013000917A (es) | 2010-07-23 | 2013-07-05 | Harvard College | Metodos para detectar las enfermedades o condiciones usando celulas fagociticas. |
| KR20130041961A (ko) | 2010-07-23 | 2013-04-25 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 체액에서 질환 또는 상태의 특징을 검출하는 방법 |
| EP2628013B1 (en) * | 2010-10-14 | 2019-06-12 | The Johns Hopkins University | Biomarkers of brain injury |
| EP3279668B1 (en) * | 2010-12-16 | 2019-05-15 | National Institute of Advanced Industrial Science and Technology | Method for enrichment and separation of spinal fluid glycoprotein, method for searching for marker for central nervous system diseases which utilizes the aforementioned method, and marker for central nervous system diseases |
| WO2012152970A1 (es) * | 2011-05-06 | 2012-11-15 | Fundació Institut D'investigació En Ciències De La Salut Germans Trias I Pujol | Método de diagnóstico del ictus isquémico |
| EP2707389B1 (en) | 2011-05-12 | 2019-10-30 | The Johns Hopkins University | Assay reagents for a neurogranin diagnostic kit |
| JP6096781B2 (ja) * | 2011-09-22 | 2017-03-15 | バイオ−ラッド ラボラトリーズ,インコーポレイティド | 生化学データ分析システム及び方法 |
| BR112014009536A2 (pt) | 2011-10-21 | 2017-04-18 | Augurex Life Sciences Corp | antígenos derivados de 14-3-3 xitrulinada e usos dos mesmos no diagnóstico de artrite reumatoide |
| WO2013090285A1 (en) * | 2011-12-14 | 2013-06-20 | University Of Rochester | Method of diagnosing mild traumatic brain injury |
| US9709573B2 (en) | 2012-03-13 | 2017-07-18 | The Johns Hopkins University | Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration |
| WO2013163345A1 (en) * | 2012-04-24 | 2013-10-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of stroke or other cerebral injury |
| KR20150035818A (ko) | 2012-06-15 | 2015-04-07 | 해리 스타일리 | 순환 병든 세포를 사용하여 질환 또는 병태를 검출하는 방법 |
| JP2015522260A (ja) | 2012-06-15 | 2015-08-06 | ハリー スティリ, | 疾患または状態を検出する方法 |
| WO2014164362A1 (en) | 2013-03-09 | 2014-10-09 | Harry Stylli | Methods of detecting prostate cancer |
| EP2965077B1 (en) | 2013-03-09 | 2022-07-13 | Harry Stylli | Methods of detecting cancer |
| CN105659093A (zh) * | 2013-06-28 | 2016-06-08 | 株式会社Mcbi | 认知功能障碍疾病的生物标记物及使用该生物标记物的认知功能障碍疾病的检测方法 |
| WO2015009907A1 (en) | 2013-07-17 | 2015-01-22 | The Johns Hopkins University | A multi-protein biomarker assay for brain injury detection and outcome |
| EP4428251A3 (en) | 2014-09-11 | 2024-12-18 | Immunis.AI, Inc. | Methods of detecting prostate cancer |
| FI20155280L (fi) * | 2015-04-15 | 2016-10-16 | Medicortex Finland Oy | Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita |
| CN105506083B (zh) * | 2015-12-24 | 2018-10-19 | 孙梅芬 | Capg在制备诊断帕金森症产品中的用途 |
| JP6947451B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
| WO2018002362A1 (en) * | 2016-06-30 | 2018-01-04 | Randox Laboratories Ltd | Measurement of fabp for diagnosis |
| JPWO2018030252A1 (ja) * | 2016-08-09 | 2019-06-20 | 大塚製薬株式会社 | 尿バイオマーカーを用いたアルツハイマー病の診断補助方法 |
| US10914748B2 (en) | 2016-09-08 | 2021-02-09 | UNIVERSITé LAVAL | Erythrocyte-derived extracellular vesicles as a biomarker for clinically assessing Parkinson's disease |
| EP3513196A1 (en) * | 2016-09-16 | 2019-07-24 | Dyax Corp. | Protein biomarkers for diseases associated with the contact activation system |
| CN110366558A (zh) | 2016-10-28 | 2019-10-22 | 班扬生物标记公司 | 针对泛素c末端水解酶l1(uch-l1)和胶质纤维酸性蛋白(gfap)的抗体及相关方法 |
| KR102466369B1 (ko) * | 2020-08-04 | 2022-11-14 | 서울대학교병원 | 자가면역 뇌염의 진단 방법 |
| JP7569552B2 (ja) * | 2021-01-29 | 2024-10-18 | 国立大学法人東北大学 | 認知症診断用のバイオマーカー |
| CN114966045A (zh) * | 2022-05-07 | 2022-08-30 | 浙江大学 | 检测抗肌球蛋白轻链1-IgG自身抗体的试剂在制备检测血管内皮损伤的试剂盒中的应用 |
| CN115166260B (zh) * | 2022-07-11 | 2023-06-13 | 东南大学 | 血浆脑细胞来源外泌体中维生素d结合蛋白在诊断抑郁症中的应用 |
| CN118624905B (zh) * | 2023-07-31 | 2025-04-01 | 中国人民解放军总医院第一医学中心 | 一种糖尿病性肾病诊断的生物标志物和试剂盒及诊断设备 |
| CN120820725A (zh) * | 2025-09-17 | 2025-10-21 | 上海交通大学医学院附属仁济医院 | 胶质纤维酸性蛋白和乳酸脱氢酶a亚型在制备诊断颅脑创伤的试剂盒中的用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4017A (en) * | 1845-05-01 | Reid r | ||
| US3015A (en) * | 1843-03-21 | Improvement in gilding, silvering | ||
| GB225245A (en) * | 1923-11-23 | 1924-12-24 | British Thomson Houston Co Ltd | Improvements in and relating to elastic fluid turbines |
| GB322063A (en) * | 1928-10-29 | 1929-11-28 | Godwin Stanley Oliver | Improvements relating to automatic vehicle-controlled track-signalling devices |
| JPH09110713A (ja) * | 1995-10-13 | 1997-04-28 | Nippon Green Ueebu Kk | グルタチオン−s−トランスフェラーゼ活性化剤並びにそれを含む医薬品及び飲食物 |
| CA2259122A1 (en) * | 1996-06-17 | 1997-12-24 | Max Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. | Novel ptp-20, pcp-2, bdp1, clk and sirp proteins and related products and methods |
| US6541615B1 (en) * | 1996-11-15 | 2003-04-01 | Max-Planck-Gellschaft Zur Foderung Der Wissenschaften E.V. | SIRP proteins and uses thereof |
| CA2263063C (en) * | 1999-02-26 | 2004-08-10 | Skye Pharmatech Incorporated | Method for diagnosing and distinguishing stroke and diagnostic devices for use therein |
| AU1701001A (en) * | 1999-11-30 | 2001-06-12 | Eberhard-Karls-Universitat Tubingen Universitatsklinikum | Antibodies against signal regulator proteins |
| GB9929140D0 (en) | 1999-12-10 | 2000-02-02 | Univ Geneve | Diagnostic assay for stroke |
| GB2360089A (en) * | 2000-03-10 | 2001-09-12 | Univ Geneve | Diagnostic assay for transmisible spongiform encephalopathies |
| EP1261875B1 (en) | 2000-03-10 | 2007-08-01 | Universite de Geneve | Diagnostic assay for transmissible spongiform encephalopathies |
| US7608406B2 (en) * | 2001-08-20 | 2009-10-27 | Biosite, Inc. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
| AU2003274368B2 (en) * | 2002-10-30 | 2008-11-20 | Proteome Sciences Plc. | Diagnostic method for transmissible spongiform encephalopathies (prion diseases) |
| EP1664795B1 (en) | 2003-09-20 | 2017-11-08 | Electrophoretics Limited | Diagnostic method for brain damage-related disorders |
| EP1673465A4 (en) * | 2003-09-29 | 2008-04-30 | Biosite Inc | PROCESS AND COMPOSITIONS FOR SEPSIS DIAGNOSIS |
| GB0419124D0 (en) | 2004-08-27 | 2004-09-29 | Proteome Sciences Plc | Methods and compositions relating to Alzheimer's disease |
| GB0421639D0 (en) | 2004-09-29 | 2004-10-27 | Proteome Sciences Plc | Methods and compositions relating to alzheimer's disease |
| WO2006061610A2 (en) | 2004-12-07 | 2006-06-15 | Electrophoretics Limited | Diagnosis of neurodegenerative diseases |
-
2005
- 2005-07-14 GB GB0514435A patent/GB2428240A/en not_active Withdrawn
-
2006
- 2006-07-14 DE DE602006011896T patent/DE602006011896D1/de active Active
- 2006-07-14 WO PCT/GB2006/050207 patent/WO2007007129A2/en not_active Ceased
- 2006-07-14 JP JP2008520966A patent/JP5281397B2/ja active Active
- 2006-07-14 ES ES06765356T patent/ES2336946T3/es active Active
- 2006-07-14 AT AT06765356T patent/ATE456055T1/de not_active IP Right Cessation
- 2006-07-14 CA CA2613991A patent/CA2613991C/en active Active
- 2006-07-14 US US11/995,501 patent/US9028825B2/en active Active
- 2006-07-14 EP EP06765356A patent/EP1902319B1/en active Active
- 2006-07-14 AU AU2006268034A patent/AU2006268034B2/en active Active
-
2013
- 2013-01-24 JP JP2013011339A patent/JP2013092538A/ja active Pending
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