DE602006011896D1 - Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden - Google Patents
Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschädenInfo
- Publication number
- DE602006011896D1 DE602006011896D1 DE602006011896T DE602006011896T DE602006011896D1 DE 602006011896 D1 DE602006011896 D1 DE 602006011896D1 DE 602006011896 T DE602006011896 T DE 602006011896T DE 602006011896 T DE602006011896 T DE 602006011896T DE 602006011896 D1 DE602006011896 D1 DE 602006011896D1
- Authority
- DE
- Germany
- Prior art keywords
- brain damage
- diseases associated
- diagnostic procedure
- polypeptide
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0514435A GB2428240A (en) | 2005-07-14 | 2005-07-14 | Diagnostic method for brain damage-related disorders |
PCT/GB2006/050207 WO2007007129A2 (en) | 2005-07-14 | 2006-07-14 | Diagnostic method for brain damage-related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006011896D1 true DE602006011896D1 (de) | 2010-03-11 |
Family
ID=34897198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006011896T Active DE602006011896D1 (de) | 2005-07-14 | 2006-07-14 | Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden |
Country Status (10)
Country | Link |
---|---|
US (1) | US9028825B2 (de) |
EP (1) | EP1902319B1 (de) |
JP (2) | JP5281397B2 (de) |
AT (1) | ATE456055T1 (de) |
AU (1) | AU2006268034B2 (de) |
CA (1) | CA2613991C (de) |
DE (1) | DE602006011896D1 (de) |
ES (1) | ES2336946T3 (de) |
GB (1) | GB2428240A (de) |
WO (1) | WO2007007129A2 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9929140D0 (en) * | 1999-12-10 | 2000-02-02 | Univ Geneve | Diagnostic assay for stroke |
US8492107B2 (en) | 2004-04-15 | 2013-07-23 | University Of Florida Research Foundation, Inc. | Neural proteins as biomarkers for nervous system injury and other neural disorders |
JP4991847B2 (ja) * | 2006-05-09 | 2012-08-01 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 溶解したタンパク質関節炎マーカー |
DE102006048201A1 (de) * | 2006-10-11 | 2008-04-17 | Ganymed Pharmaceuticals Ag | Autoantigene zur verbesserten Diagnose, Prognose und Therapie von entzündlichen neurologischen Erkrankungen |
WO2009036336A2 (en) * | 2007-09-12 | 2009-03-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomarkers for motor neuron disease |
MX340916B (es) | 2008-01-18 | 2016-07-29 | President And Fellows Of Harvard College * | Metodos para detectar señales de identificacion de enfermedad o condiciones en fluidos corporales. |
US20120003225A1 (en) * | 2008-05-09 | 2012-01-05 | Duke University | Autoantibodies in the detection and treatment of cancer |
CA2750076A1 (en) * | 2009-01-26 | 2010-07-29 | Electrophoretics Limited | Methods |
CA2751090A1 (en) * | 2009-01-30 | 2010-08-05 | Bio-Rad Innovations | Method for the in vitro diagnosis of stroke |
KR101894597B1 (ko) | 2009-03-11 | 2018-10-04 | 오거렉스 라이프 사이언시스 코포레이션 | 관절염 상태를 특성화하는 조성물 및 방법 |
EP2462444B1 (de) * | 2009-08-07 | 2018-10-03 | Affinimark Technologies, Inc. | Verfahren zur immunologischen identifikation einer liquor-flüssigkeit |
AU2010291933B2 (en) * | 2009-09-14 | 2016-09-08 | Banyan Biomarkers, Inc. | Micro-RNA, autoantibody and protein markers for diagnosis of neuronal injury |
US9200322B2 (en) * | 2010-02-23 | 2015-12-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Biomarkers for acute ischemic stroke |
GB201008541D0 (en) * | 2010-05-21 | 2010-07-07 | Univ Geneve | Diagnostic methods |
BR112013001752A2 (pt) | 2010-07-23 | 2016-05-31 | Harvard College | método de detectar doenças ou condições usando células fagocídicas |
AU2011280936A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting prenatal or pregnancy-related diseases or conditions |
KR20130041961A (ko) | 2010-07-23 | 2013-04-25 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 체액에서 질환 또는 상태의 특징을 검출하는 방법 |
EP2596116A4 (de) | 2010-07-23 | 2014-03-19 | Harvard College | Verfahren zur erkennung von autoimmun- oder autoimmunbezogenen erkrankungen oder leiden |
WO2012051519A2 (en) * | 2010-10-14 | 2012-04-19 | The Johns Hopkins University | Biomarkers of brain injury |
EP2653476B1 (de) * | 2010-12-16 | 2017-04-26 | National Institute of Advanced Industrial Science And Technology | Verfahren zur anreicherung und trennung von rückenmarksflüssigkeitsglykoprotein, verfahren zum suchen von markern für erkrankungen des zentralnervensystems unter verwendung dieses verfahrens und marker für erkrankungen des zentralnervensystems |
WO2012152970A1 (es) * | 2011-05-06 | 2012-11-15 | Fundació Institut D'investigació En Ciències De La Salut Germans Trias I Pujol | Método de diagnóstico del ictus isquémico |
JP2014518624A (ja) | 2011-05-12 | 2014-08-07 | ザ・ジョンズ・ホプキンス・ユニバーシティー | ニューログラニン診断キットのためのアッセイ試薬 |
WO2013044244A1 (en) | 2011-09-22 | 2013-03-28 | Bio-Rad Laboratories, Inc. | Systems and methods for biochemical data analysis |
US10132806B2 (en) | 2011-10-21 | 2018-11-20 | Augurex Life Sciences Corp. | Antigens derived from citrullinated 14-3-3 and uses thereof in the diagnosis of rheumatoid arthritis |
US20140370531A1 (en) * | 2011-12-14 | 2014-12-18 | University Of Rochester | Method of diagnosing mild traumatic brain injury |
JP6392202B2 (ja) | 2012-03-13 | 2018-09-19 | ザ・ジョンズ・ホプキンス・ユニバーシティ | 脳損傷または神経変性のバイオマーカーとしてのシトルリン化脳および神経タンパク質 |
US9733261B2 (en) * | 2012-04-24 | 2017-08-15 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of stroke or other cerebral injury |
KR20150035818A (ko) | 2012-06-15 | 2015-04-07 | 해리 스타일리 | 순환 병든 세포를 사용하여 질환 또는 병태를 검출하는 방법 |
JP2015522260A (ja) | 2012-06-15 | 2015-08-06 | ハリー スティリ, | 疾患または状態を検出する方法 |
WO2014164366A1 (en) | 2013-03-09 | 2014-10-09 | Harry Stylli | Methods of detecting cancer |
US11585814B2 (en) | 2013-03-09 | 2023-02-21 | Immunis.Ai, Inc. | Methods of detecting prostate cancer |
CA2916861A1 (en) * | 2013-06-28 | 2014-12-31 | University Of Tsukuba | Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkers |
US10534003B2 (en) | 2013-07-17 | 2020-01-14 | The Johns Hopkins University | Multi-protein biomarker assay for brain injury detection and outcome |
EP4075139A1 (de) | 2014-09-11 | 2022-10-19 | Harry Stylli | Verfahren zum nachweis von prostatakrebs |
FI20155280A (fi) * | 2015-04-15 | 2016-10-16 | Medicortex Finland Oy | Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita |
CN105506083B (zh) * | 2015-12-24 | 2018-10-19 | 孙梅芬 | Capg在制备诊断帕金森症产品中的用途 |
JP6947451B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
US20190154672A1 (en) * | 2016-06-30 | 2019-05-23 | Randox Laboratories Ltd. | Measurement of fabp for diagnosis |
EP3499230A4 (de) * | 2016-08-09 | 2020-07-29 | Otsuka Pharmaceutical Co., Ltd. | Verfahren zur unterstützung der diagnose von morbus alzheimer mittels urinbiomarker |
US10914748B2 (en) | 2016-09-08 | 2021-02-09 | UNIVERSITé LAVAL | Erythrocyte-derived extracellular vesicles as a biomarker for clinically assessing Parkinson's disease |
KR102466369B1 (ko) * | 2020-08-04 | 2022-11-14 | 서울대학교병원 | 자가면역 뇌염의 진단 방법 |
JP2022116453A (ja) * | 2021-01-29 | 2022-08-10 | 国立大学法人東北大学 | 認知症診断用のバイオマーカー |
CN114966045A (zh) * | 2022-05-07 | 2022-08-30 | 浙江大学 | 检测抗肌球蛋白轻链1-IgG自身抗体的试剂在制备检测血管内皮损伤的试剂盒中的应用 |
CN115166260B (zh) * | 2022-07-11 | 2023-06-13 | 东南大学 | 血浆脑细胞来源外泌体中维生素d结合蛋白在诊断抑郁症中的应用 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4017A (en) * | 1845-05-01 | Reid r | ||
US3015A (en) * | 1843-03-21 | Improvement in gilding, silvering | ||
GB225245A (en) * | 1923-11-23 | 1924-12-24 | British Thomson Houston Co Ltd | Improvements in and relating to elastic fluid turbines |
GB322063A (en) * | 1928-10-29 | 1929-11-28 | Godwin Stanley Oliver | Improvements relating to automatic vehicle-controlled track-signalling devices |
JPH09110713A (ja) * | 1995-10-13 | 1997-04-28 | Nippon Green Ueebu Kk | グルタチオン−s−トランスフェラーゼ活性化剤並びにそれを含む医薬品及び飲食物 |
AU3457497A (en) * | 1996-06-17 | 1998-01-07 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Novel PTP20, PCP-2, BDP1, CLK and SIRP proteins and related products and method |
US6541615B1 (en) * | 1996-11-15 | 2003-04-01 | Max-Planck-Gellschaft Zur Foderung Der Wissenschaften E.V. | SIRP proteins and uses thereof |
CA2263063C (en) * | 1999-02-26 | 2004-08-10 | Skye Pharmatech Incorporated | Method for diagnosing and distinguishing stroke and diagnostic devices for use therein |
WO2001040307A1 (de) * | 1999-11-30 | 2001-06-07 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Antikörper gegen signal-regulator-proteine |
GB9929140D0 (en) | 1999-12-10 | 2000-02-02 | Univ Geneve | Diagnostic assay for stroke |
WO2001067108A2 (en) | 2000-03-10 | 2001-09-13 | Universite De Geneve | Diagnostic assay for transmissible spongiform encephalopathies |
GB2360089A (en) * | 2000-03-10 | 2001-09-12 | Univ Geneve | Diagnostic assay for transmisible spongiform encephalopathies |
US7608406B2 (en) * | 2001-08-20 | 2009-10-27 | Biosite, Inc. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
EP1556702A2 (de) | 2002-10-30 | 2005-07-27 | Proteome Sciences Plc | Methoden, um übertragbare spongiforme enzephalopathien (prionenerkrankungen), zu diagnostizieren |
EP1664795B1 (de) * | 2003-09-20 | 2017-11-08 | Electrophoretics Limited | Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden |
WO2005033327A2 (en) * | 2003-09-29 | 2005-04-14 | Biosite Incorporated | Methods and compositions for the diagnosis of sepsis |
GB0419124D0 (en) | 2004-08-27 | 2004-09-29 | Proteome Sciences Plc | Methods and compositions relating to Alzheimer's disease |
GB0421639D0 (en) | 2004-09-29 | 2004-10-27 | Proteome Sciences Plc | Methods and compositions relating to alzheimer's disease |
EP1825274B1 (de) | 2004-12-07 | 2009-11-18 | Electrophoretics Limited | Monitorierung von Huntington's Disease |
-
2005
- 2005-07-14 GB GB0514435A patent/GB2428240A/en not_active Withdrawn
-
2006
- 2006-07-14 ES ES06765356T patent/ES2336946T3/es active Active
- 2006-07-14 WO PCT/GB2006/050207 patent/WO2007007129A2/en not_active Application Discontinuation
- 2006-07-14 AT AT06765356T patent/ATE456055T1/de not_active IP Right Cessation
- 2006-07-14 AU AU2006268034A patent/AU2006268034B2/en active Active
- 2006-07-14 JP JP2008520966A patent/JP5281397B2/ja active Active
- 2006-07-14 EP EP06765356A patent/EP1902319B1/de active Active
- 2006-07-14 CA CA2613991A patent/CA2613991C/en active Active
- 2006-07-14 US US11/995,501 patent/US9028825B2/en active Active
- 2006-07-14 DE DE602006011896T patent/DE602006011896D1/de active Active
-
2013
- 2013-01-24 JP JP2013011339A patent/JP2013092538A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2613991C (en) | 2017-03-07 |
AU2006268034A1 (en) | 2007-01-18 |
ATE456055T1 (de) | 2010-02-15 |
ES2336946T3 (es) | 2010-04-19 |
JP2009501333A (ja) | 2009-01-15 |
WO2007007129A2 (en) | 2007-01-18 |
US9028825B2 (en) | 2015-05-12 |
AU2006268034B2 (en) | 2012-02-02 |
US20080220013A1 (en) | 2008-09-11 |
WO2007007129A3 (en) | 2007-05-31 |
JP5281397B2 (ja) | 2013-09-04 |
GB2428240A (en) | 2007-01-24 |
EP1902319A2 (de) | 2008-03-26 |
CA2613991A1 (en) | 2007-01-18 |
EP1902319B1 (de) | 2010-01-20 |
JP2013092538A (ja) | 2013-05-16 |
GB0514435D0 (en) | 2005-08-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |