ATE456055T1 - Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden - Google Patents
Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschädenInfo
- Publication number
- ATE456055T1 ATE456055T1 AT06765356T AT06765356T ATE456055T1 AT E456055 T1 ATE456055 T1 AT E456055T1 AT 06765356 T AT06765356 T AT 06765356T AT 06765356 T AT06765356 T AT 06765356T AT E456055 T1 ATE456055 T1 AT E456055T1
- Authority
- AT
- Austria
- Prior art keywords
- brain damage
- diagnostic methods
- diseases related
- polypeptide
- subject
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0514435A GB2428240A (en) | 2005-07-14 | 2005-07-14 | Diagnostic method for brain damage-related disorders |
PCT/GB2006/050207 WO2007007129A2 (en) | 2005-07-14 | 2006-07-14 | Diagnostic method for brain damage-related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE456055T1 true ATE456055T1 (de) | 2010-02-15 |
Family
ID=34897198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06765356T ATE456055T1 (de) | 2005-07-14 | 2006-07-14 | Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden |
Country Status (10)
Country | Link |
---|---|
US (1) | US9028825B2 (de) |
EP (1) | EP1902319B1 (de) |
JP (2) | JP5281397B2 (de) |
AT (1) | ATE456055T1 (de) |
AU (1) | AU2006268034B2 (de) |
CA (1) | CA2613991C (de) |
DE (1) | DE602006011896D1 (de) |
ES (1) | ES2336946T3 (de) |
GB (1) | GB2428240A (de) |
WO (1) | WO2007007129A2 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9929140D0 (en) * | 1999-12-10 | 2000-02-02 | Univ Geneve | Diagnostic assay for stroke |
US8492107B2 (en) | 2004-04-15 | 2013-07-23 | University Of Florida Research Foundation, Inc. | Neural proteins as biomarkers for nervous system injury and other neural disorders |
JP4991847B2 (ja) | 2006-05-09 | 2012-08-01 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 溶解したタンパク質関節炎マーカー |
DE102006048201A1 (de) * | 2006-10-11 | 2008-04-17 | Ganymed Pharmaceuticals Ag | Autoantigene zur verbesserten Diagnose, Prognose und Therapie von entzündlichen neurologischen Erkrankungen |
WO2009036336A2 (en) * | 2007-09-12 | 2009-03-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomarkers for motor neuron disease |
ES2809171T3 (es) | 2008-01-18 | 2021-03-03 | Harvard College | Métodos para detectar distintivos de enfermedades o afecciones en fluidos corporales |
CA2725548A1 (en) * | 2008-05-09 | 2009-11-12 | Duke University | Autoantibodies in the detection and treatment of cancer |
CA2733990C (en) | 2008-08-11 | 2018-12-11 | Banyan Biomarkers, Inc. | Biomarker detection process and assay of neurological condition |
CA2750076A1 (en) * | 2009-01-26 | 2010-07-29 | Electrophoretics Limited | Methods |
WO2010086697A1 (en) * | 2009-01-30 | 2010-08-05 | Bio-Rad Pasteur | Method for the in vitro diagnosis of stroke |
KR101894597B1 (ko) | 2009-03-11 | 2018-10-04 | 오거렉스 라이프 사이언시스 코포레이션 | 관절염 상태를 특성화하는 조성물 및 방법 |
EP2462444B1 (de) * | 2009-08-07 | 2018-10-03 | Affinimark Technologies, Inc. | Verfahren zur immunologischen identifikation einer liquor-flüssigkeit |
US20130022982A1 (en) | 2009-09-14 | 2013-01-24 | Kevin Ka-Wang Wang | Micro-rna, autoantibody and protein markers for diagnosis of neuronal injury |
US9200322B2 (en) * | 2010-02-23 | 2015-12-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Biomarkers for acute ischemic stroke |
GB201008541D0 (en) * | 2010-05-21 | 2010-07-07 | Univ Geneve | Diagnostic methods |
CA2806304A1 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting prenatal or pregnancy-related diseases or conditions |
AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
SG10201505723UA (en) | 2010-07-23 | 2015-09-29 | Harvard College | Methods for detecting signatures of disease or conditions in bodily fluids |
CN103124795A (zh) | 2010-07-23 | 2013-05-29 | 哈佛大学校长及研究员协会 | 利用吞噬细胞检测疾病或病症的方法 |
JP6071886B2 (ja) * | 2010-10-14 | 2017-02-01 | ザ・ジョンズ・ホプキンス・ユニバーシティ | 脳損傷のバイオマーカー |
US20140323324A1 (en) * | 2010-12-16 | 2014-10-30 | National Institute Of Advanced Industrial Science And Technology | Method for Enrichment and Separation of Spinal Fluid Glycoprotein, Method for Searching for Marker for Central Nervous System Diseases Which Utilizes the Aforementioned Method, and Marker for Central Nervous System Diseases |
WO2012152970A1 (es) * | 2011-05-06 | 2012-11-15 | Fundació Institut D'investigació En Ciències De La Salut Germans Trias I Pujol | Método de diagnóstico del ictus isquémico |
US20140141458A1 (en) | 2011-05-12 | 2014-05-22 | The Johns Hopkins University | Assay reagents for a neurogranin diagnostic kit |
CN103988078B (zh) * | 2011-09-22 | 2016-11-02 | 生物辐射实验室股份有限公司 | 用于生化数据分析的系统和方法 |
JP6844939B2 (ja) | 2011-10-21 | 2021-03-17 | オ−グレックス ライフ サイエンシズ コーポレイション | シトルリン化14−3−3由来の抗原、及び関節リウマチの診断におけるそれの使用 |
WO2013090285A1 (en) * | 2011-12-14 | 2013-06-20 | University Of Rochester | Method of diagnosing mild traumatic brain injury |
WO2013138509A1 (en) | 2012-03-13 | 2013-09-19 | The Johns Hopkins University | Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration |
EP2841945A4 (de) * | 2012-04-24 | 2016-04-27 | Astute Medical Inc | Verfahren und zusammensetzungen zur diagnose und prognose von schlaganfall oder anderen hirnläsionen |
US20150141260A1 (en) | 2012-06-15 | 2015-05-21 | Harry Stylli | Methods of detecting diseases or conditions using circulating diseased cells |
JP2015522260A (ja) | 2012-06-15 | 2015-08-06 | ハリー スティリ, | 疾患または状態を検出する方法 |
WO2014164366A1 (en) | 2013-03-09 | 2014-10-09 | Harry Stylli | Methods of detecting cancer |
EP2965086A4 (de) | 2013-03-09 | 2017-02-08 | Harry Stylli | Verfahren zum nachweis von prostatakrebs |
JP6265507B2 (ja) * | 2013-06-28 | 2018-01-24 | 株式会社Mcbi | 認知機能障害疾患のバイオマーカー及び当該バイオマーカーを用いる認知機能障害疾患の検出方法 |
EP3757226A3 (de) | 2013-07-17 | 2021-05-05 | The Johns Hopkins University | Multiprotein-biomarkertest für den nachweis von hirnläsionen und ergebnis |
EP3693742B1 (de) | 2014-09-11 | 2022-04-06 | Harry Stylli | Verfahren zum nachweis von prostatakrebs |
FI20155280A (fi) * | 2015-04-15 | 2016-10-16 | Medicortex Finland Oy | Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita |
CN105506083B (zh) * | 2015-12-24 | 2018-10-19 | 孙梅芬 | Capg在制备诊断帕金森症产品中的用途 |
JP6947451B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
US20190154672A1 (en) * | 2016-06-30 | 2019-05-23 | Randox Laboratories Ltd. | Measurement of fabp for diagnosis |
CN109791139A (zh) * | 2016-08-09 | 2019-05-21 | 大塚制药株式会社 | 使用尿液生物标记的阿兹海默氏症的辅助诊断方法 |
US10914748B2 (en) | 2016-09-08 | 2021-02-09 | UNIVERSITé LAVAL | Erythrocyte-derived extracellular vesicles as a biomarker for clinically assessing Parkinson's disease |
KR102466369B1 (ko) * | 2020-08-04 | 2022-11-14 | 서울대학교병원 | 자가면역 뇌염의 진단 방법 |
JP2022116453A (ja) * | 2021-01-29 | 2022-08-10 | 国立大学法人東北大学 | 認知症診断用のバイオマーカー |
CN114966045A (zh) * | 2022-05-07 | 2022-08-30 | 浙江大学 | 检测抗肌球蛋白轻链1-IgG自身抗体的试剂在制备检测血管内皮损伤的试剂盒中的应用 |
CN115166260B (zh) * | 2022-07-11 | 2023-06-13 | 东南大学 | 血浆脑细胞来源外泌体中维生素d结合蛋白在诊断抑郁症中的应用 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3015A (en) * | 1843-03-21 | Improvement in gilding, silvering | ||
US4017A (en) * | 1845-05-01 | Reid r | ||
GB225245A (en) * | 1923-11-23 | 1924-12-24 | British Thomson Houston Co Ltd | Improvements in and relating to elastic fluid turbines |
GB322063A (en) * | 1928-10-29 | 1929-11-28 | Godwin Stanley Oliver | Improvements relating to automatic vehicle-controlled track-signalling devices |
JPH09110713A (ja) * | 1995-10-13 | 1997-04-28 | Nippon Green Ueebu Kk | グルタチオン−s−トランスフェラーゼ活性化剤並びにそれを含む医薬品及び飲食物 |
EP0914452A2 (de) * | 1996-06-17 | 1999-05-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Ptp-20,pcp-2bdp1, clk und sirp proteine und verwandte produkte |
US6541615B1 (en) * | 1996-11-15 | 2003-04-01 | Max-Planck-Gellschaft Zur Foderung Der Wissenschaften E.V. | SIRP proteins and uses thereof |
CA2263063C (en) * | 1999-02-26 | 2004-08-10 | Skye Pharmatech Incorporated | Method for diagnosing and distinguishing stroke and diagnostic devices for use therein |
EP1244707A1 (de) * | 1999-11-30 | 2002-10-02 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Antikörper gegen signal-regulator-proteine |
GB9929140D0 (en) | 1999-12-10 | 2000-02-02 | Univ Geneve | Diagnostic assay for stroke |
ATE368858T1 (de) | 2000-03-10 | 2007-08-15 | Univ Geneve | Verfahren zur diagnose von transmissiblen spongiformen encephalopathien |
GB2360089A (en) * | 2000-03-10 | 2001-09-12 | Univ Geneve | Diagnostic assay for transmisible spongiform encephalopathies |
US7608406B2 (en) | 2001-08-20 | 2009-10-27 | Biosite, Inc. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
EP2211181A1 (de) * | 2002-10-30 | 2010-07-28 | Proteome Sciences Plc | Methoden um übertragbare Spongiforme Enzephalopathien zu diagnostizieren |
EP1664795B1 (de) * | 2003-09-20 | 2017-11-08 | Electrophoretics Limited | Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden |
WO2005033327A2 (en) * | 2003-09-29 | 2005-04-14 | Biosite Incorporated | Methods and compositions for the diagnosis of sepsis |
GB0419124D0 (en) | 2004-08-27 | 2004-09-29 | Proteome Sciences Plc | Methods and compositions relating to Alzheimer's disease |
GB0421639D0 (en) | 2004-09-29 | 2004-10-27 | Proteome Sciences Plc | Methods and compositions relating to alzheimer's disease |
EP1825274B1 (de) | 2004-12-07 | 2009-11-18 | Electrophoretics Limited | Monitorierung von Huntington's Disease |
-
2005
- 2005-07-14 GB GB0514435A patent/GB2428240A/en not_active Withdrawn
-
2006
- 2006-07-14 DE DE602006011896T patent/DE602006011896D1/de active Active
- 2006-07-14 AT AT06765356T patent/ATE456055T1/de not_active IP Right Cessation
- 2006-07-14 US US11/995,501 patent/US9028825B2/en active Active
- 2006-07-14 CA CA2613991A patent/CA2613991C/en active Active
- 2006-07-14 JP JP2008520966A patent/JP5281397B2/ja active Active
- 2006-07-14 WO PCT/GB2006/050207 patent/WO2007007129A2/en not_active Application Discontinuation
- 2006-07-14 ES ES06765356T patent/ES2336946T3/es active Active
- 2006-07-14 EP EP06765356A patent/EP1902319B1/de active Active
- 2006-07-14 AU AU2006268034A patent/AU2006268034B2/en active Active
-
2013
- 2013-01-24 JP JP2013011339A patent/JP2013092538A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2613991C (en) | 2017-03-07 |
AU2006268034B2 (en) | 2012-02-02 |
EP1902319B1 (de) | 2010-01-20 |
US20080220013A1 (en) | 2008-09-11 |
EP1902319A2 (de) | 2008-03-26 |
WO2007007129A2 (en) | 2007-01-18 |
WO2007007129A3 (en) | 2007-05-31 |
CA2613991A1 (en) | 2007-01-18 |
DE602006011896D1 (de) | 2010-03-11 |
JP5281397B2 (ja) | 2013-09-04 |
AU2006268034A1 (en) | 2007-01-18 |
US9028825B2 (en) | 2015-05-12 |
GB0514435D0 (en) | 2005-08-17 |
ES2336946T3 (es) | 2010-04-19 |
GB2428240A (en) | 2007-01-24 |
JP2009501333A (ja) | 2009-01-15 |
JP2013092538A (ja) | 2013-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |