ATE511651T1 - Transglutaminase 6 als diagnostischer indikator für autoimmunerkrankungen - Google Patents
Transglutaminase 6 als diagnostischer indikator für autoimmunerkrankungenInfo
- Publication number
- ATE511651T1 ATE511651T1 AT07007262T AT07007262T ATE511651T1 AT E511651 T1 ATE511651 T1 AT E511651T1 AT 07007262 T AT07007262 T AT 07007262T AT 07007262 T AT07007262 T AT 07007262T AT E511651 T1 ATE511651 T1 AT E511651T1
- Authority
- AT
- Austria
- Prior art keywords
- transglutaminase
- autoimmune diseases
- diagnostic indicator
- novel antigen
- diagnostic
- Prior art date
Links
- 101000666174 Homo sapiens Protein-glutamine gamma-glutamyltransferase 6 Proteins 0.000 title abstract 2
- 102100038112 Protein-glutamine gamma-glutamyltransferase 6 Human genes 0.000 title abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000006472 autoimmune response Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/91045—Acyltransferases (2.3)
- G01N2333/91074—Aminoacyltransferases (general) (2.3.2)
- G01N2333/9108—Aminoacyltransferases (general) (2.3.2) with definite EC number (2.3.2.-)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07007262A EP1978364B1 (de) | 2007-04-06 | 2007-04-06 | Transglutaminase 6 als diagnostischer Indikator für Autoimmunerkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE511651T1 true ATE511651T1 (de) | 2011-06-15 |
Family
ID=38158045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07007262T ATE511651T1 (de) | 2007-04-06 | 2007-04-06 | Transglutaminase 6 als diagnostischer indikator für autoimmunerkrankungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130196336A1 (de) |
| EP (1) | EP1978364B1 (de) |
| AT (1) | ATE511651T1 (de) |
| AU (1) | AU2008234999A1 (de) |
| CA (1) | CA2683394A1 (de) |
| RU (1) | RU2009140980A (de) |
| WO (1) | WO2008122432A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU0900195D0 (en) * | 2009-04-01 | 2009-06-29 | Debreceni Egyetem | Diagnosis and treatment of gluten-induced autoimmune diseases |
| HU0900199D0 (en) * | 2009-04-01 | 2009-06-29 | Debreceni Egyetem | Diagnosis of gluten-induced autoimmune diseases |
| EP2322926A1 (de) * | 2009-11-11 | 2011-05-18 | Zedira GmbH | Stabilisiertes Transglutaminase als diagnostischer Indikator für Autoimmunerkrankungen |
| WO2011057826A1 (en) * | 2009-11-11 | 2011-05-19 | Zedira Gmbh | Stabilized open form transglutaminase as a diagnostic indicator for autoimmune diseases |
| JP2013528799A (ja) * | 2010-05-13 | 2013-07-11 | ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 神経変性疾患の検知および診断のための診断用自己抗体プロファイル |
| CN102220337B (zh) * | 2010-09-19 | 2012-11-14 | 中南大学 | 一种遗传性脊髓小脑共济失调相关基因 |
| RU2441240C1 (ru) * | 2010-10-05 | 2012-01-27 | Государственное образовательное учреждение высшего профессионального образования "Московский государственный медико-стоматологический университет" Министерства здравоохранения и социального развития Российской Федерации | Способ диагностики аксонально-демиелинизирующих полиневропатий |
| MX354089B (es) * | 2011-01-20 | 2018-02-09 | Cyrex Laboratories Llc | Metodos y aparato para la deteccion de sensibilidad al gluten y su diferenciacion de la enfermedad celiaca. |
| WO2013010003A1 (en) | 2011-07-12 | 2013-01-17 | University Of Medicine And Dentistry Of New Jersey | Diagnostic biomarker profiles for the detection and diagnosis of alzheimer's disease |
| EP3260864B1 (de) * | 2016-06-21 | 2024-08-07 | Euroimmun Medizinische Labordiagnostika AG | Diagnostischer co-inkubations-assay |
| IT202100019616A1 (it) * | 2021-07-23 | 2023-01-23 | Univ Degli Studi Di Trieste | Nuovo metodo |
| CN116515786B (zh) * | 2023-04-26 | 2024-05-28 | 广东医科大学 | 一种人tgm3乙酰化多肽、抗原、抗体及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19630557C2 (de) | 1996-07-18 | 1998-07-02 | Schuppan Detlef Priv Doz Dr Dr | Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Gewebe-Transglutaminase (tTG) sowie die Verwendung von tTG in Diagnose und Therapie |
| EP1200827B1 (de) | 1999-06-28 | 2004-06-16 | Immundiagnostik AG | Diagnose der glutensensibilitätsenteropathie und anderer autoimmunerkrangungen |
| DE60140552D1 (de) | 2000-09-15 | 2009-12-31 | Zedira Gmbh | Transglutaminase genprodukte |
| GB0103024D0 (en) * | 2001-02-07 | 2001-03-21 | Rsr Ltd | Assay for Autoantibodies to tissue transglutaminase |
-
2007
- 2007-04-06 EP EP07007262A patent/EP1978364B1/de active Active
- 2007-04-06 AT AT07007262T patent/ATE511651T1/de not_active IP Right Cessation
-
2008
- 2008-04-07 US US12/594,926 patent/US20130196336A1/en not_active Abandoned
- 2008-04-07 WO PCT/EP2008/002744 patent/WO2008122432A1/en not_active Ceased
- 2008-04-07 RU RU2009140980/15A patent/RU2009140980A/ru not_active Application Discontinuation
- 2008-04-07 CA CA002683394A patent/CA2683394A1/en not_active Abandoned
- 2008-04-07 AU AU2008234999A patent/AU2008234999A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008234999A1 (en) | 2008-10-16 |
| EP1978364A1 (de) | 2008-10-08 |
| US20130196336A1 (en) | 2013-08-01 |
| EP1978364B1 (de) | 2011-06-01 |
| RU2009140980A (ru) | 2011-05-20 |
| CA2683394A1 (en) | 2008-10-16 |
| WO2008122432A1 (en) | 2008-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |