GB2428240A - Diagnostic method for brain damage-related disorders - Google Patents

Diagnostic method for brain damage-related disorders Download PDF

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Publication number
GB2428240A
GB2428240A GB0514435A GB0514435A GB2428240A GB 2428240 A GB2428240 A GB 2428240A GB 0514435 A GB0514435 A GB 0514435A GB 0514435 A GB0514435 A GB 0514435A GB 2428240 A GB2428240 A GB 2428240A
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United Kingdom
Prior art keywords
protein
polypeptide
brain damage
alpha
chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB0514435A
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English (en)
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GB0514435D0 (en
Inventor
Jean-Charles Sanchez
Denis Francois Hochstrasser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GEN VE, University of
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GEN VE, University of
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GEN VE, University of filed Critical GEN VE, University of
Priority to GB0514435A priority Critical patent/GB2428240A/en
Publication of GB0514435D0 publication Critical patent/GB0514435D0/en
Priority to AU2006268034A priority patent/AU2006268034B2/en
Priority to PCT/GB2006/050207 priority patent/WO2007007129A2/en
Priority to JP2008520966A priority patent/JP5281397B2/ja
Priority to DE602006011896T priority patent/DE602006011896D1/de
Priority to US11/995,501 priority patent/US9028825B2/en
Priority to AT06765356T priority patent/ATE456055T1/de
Priority to CA2613991A priority patent/CA2613991C/en
Priority to ES06765356T priority patent/ES2336946T3/es
Priority to EP06765356A priority patent/EP1902319B1/en
Publication of GB2428240A publication Critical patent/GB2428240A/en
Priority to JP2013011339A priority patent/JP2013092538A/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/30—Psychoses; Psychiatry

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
GB0514435A 2005-07-14 2005-07-14 Diagnostic method for brain damage-related disorders Withdrawn GB2428240A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
GB0514435A GB2428240A (en) 2005-07-14 2005-07-14 Diagnostic method for brain damage-related disorders
EP06765356A EP1902319B1 (en) 2005-07-14 2006-07-14 Diagnostic method for brain damage-related disorders
DE602006011896T DE602006011896D1 (de) 2005-07-14 2006-07-14 Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden
PCT/GB2006/050207 WO2007007129A2 (en) 2005-07-14 2006-07-14 Diagnostic method for brain damage-related disorders
JP2008520966A JP5281397B2 (ja) 2005-07-14 2006-07-14 脳損傷関連障害の診断法
AU2006268034A AU2006268034B2 (en) 2005-07-14 2006-07-14 Diagnostic method for brain damage-related disorders
US11/995,501 US9028825B2 (en) 2005-07-14 2006-07-14 Diagnostic method for brain damage-related disorders
AT06765356T ATE456055T1 (de) 2005-07-14 2006-07-14 Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden
CA2613991A CA2613991C (en) 2005-07-14 2006-07-14 Diagnostic method for brain damage-related disorders
ES06765356T ES2336946T3 (es) 2005-07-14 2006-07-14 Metodo de diagnostico para trastornos relacionados con daño cerebral.
JP2013011339A JP2013092538A (ja) 2005-07-14 2013-01-24 脳損傷関連障害の診断法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0514435A GB2428240A (en) 2005-07-14 2005-07-14 Diagnostic method for brain damage-related disorders

Publications (2)

Publication Number Publication Date
GB0514435D0 GB0514435D0 (en) 2005-08-17
GB2428240A true GB2428240A (en) 2007-01-24

Family

ID=34897198

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0514435A Withdrawn GB2428240A (en) 2005-07-14 2005-07-14 Diagnostic method for brain damage-related disorders

Country Status (10)

Country Link
US (1) US9028825B2 (enExample)
EP (1) EP1902319B1 (enExample)
JP (2) JP5281397B2 (enExample)
AT (1) ATE456055T1 (enExample)
AU (1) AU2006268034B2 (enExample)
CA (1) CA2613991C (enExample)
DE (1) DE602006011896D1 (enExample)
ES (1) ES2336946T3 (enExample)
GB (1) GB2428240A (enExample)
WO (1) WO2007007129A2 (enExample)

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Publication number Publication date
AU2006268034A1 (en) 2007-01-18
WO2007007129A3 (en) 2007-05-31
CA2613991C (en) 2017-03-07
JP2009501333A (ja) 2009-01-15
ATE456055T1 (de) 2010-02-15
DE602006011896D1 (de) 2010-03-11
AU2006268034B2 (en) 2012-02-02
US20080220013A1 (en) 2008-09-11
EP1902319B1 (en) 2010-01-20
US9028825B2 (en) 2015-05-12
JP2013092538A (ja) 2013-05-16
GB0514435D0 (en) 2005-08-17
JP5281397B2 (ja) 2013-09-04
WO2007007129A2 (en) 2007-01-18
ES2336946T3 (es) 2010-04-19
CA2613991A1 (en) 2007-01-18
EP1902319A2 (en) 2008-03-26

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