JP2009007379A5 - - Google Patents
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- Publication number
- JP2009007379A5 JP2009007379A5 JP2008221521A JP2008221521A JP2009007379A5 JP 2009007379 A5 JP2009007379 A5 JP 2009007379A5 JP 2008221521 A JP2008221521 A JP 2008221521A JP 2008221521 A JP2008221521 A JP 2008221521A JP 2009007379 A5 JP2009007379 A5 JP 2009007379A5
- Authority
- JP
- Japan
- Prior art keywords
- oral administration
- water
- swellable gel
- forming
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims 37
- 229940079593 drug Drugs 0.000 claims 15
- 239000003814 drug Substances 0.000 claims 15
- OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 claims 2
- SATHPVQTSSUFFW-UHFFFAOYSA-N 4-[6-[(3,5-dihydroxy-4-methoxyoxan-2-yl)oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-2-(hydroxymethyl)-6-methyloxane-3,5-diol Chemical compound OC1C(OC)C(O)COC1OCC1C(O)C(OC)C(O)C(OC2C(C(CO)OC(C)C2O)O)O1 SATHPVQTSSUFFW-UHFFFAOYSA-N 0.000 claims 2
- 229920001817 Agar Polymers 0.000 claims 2
- 229920000189 Arabinogalactan Polymers 0.000 claims 2
- 239000001904 Arabinogalactan Substances 0.000 claims 2
- 229920002307 Dextran Polymers 0.000 claims 2
- 229920000926 Galactomannan Polymers 0.000 claims 2
- 229920002148 Gellan gum Polymers 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims 2
- 239000000853 adhesive Substances 0.000 claims 2
- 230000001070 adhesive effect Effects 0.000 claims 2
- 239000008272 agar Substances 0.000 claims 2
- 235000010419 agar Nutrition 0.000 claims 2
- 235000010443 alginic acid Nutrition 0.000 claims 2
- 239000000783 alginic acid Substances 0.000 claims 2
- 229920000615 alginic acid Polymers 0.000 claims 2
- 229960001126 alginic acid Drugs 0.000 claims 2
- 150000004781 alginic acids Chemical class 0.000 claims 2
- 229920013820 alkyl cellulose Polymers 0.000 claims 2
- 235000019312 arabinogalactan Nutrition 0.000 claims 2
- 239000000216 gellan gum Substances 0.000 claims 2
- 235000010492 gellan gum Nutrition 0.000 claims 2
- 229920013821 hydroxy alkyl cellulose Polymers 0.000 claims 2
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 claims 2
- 229920001277 pectin Polymers 0.000 claims 2
- 235000010987 pectin Nutrition 0.000 claims 2
- 239000001814 pectin Substances 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 239000008107 starch Substances 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 229920001285 xanthan gum Polymers 0.000 claims 2
- 239000000230 xanthan gum Substances 0.000 claims 2
- 235000010493 xanthan gum Nutrition 0.000 claims 2
- 229940082509 xanthan gum Drugs 0.000 claims 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 229920001519 homopolymer Polymers 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008221521A JP5008205B2 (ja) | 2001-04-24 | 2008-08-29 | 経口投与剤及び経口投与剤保持体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001125804 | 2001-04-24 | ||
| JP2001125804 | 2001-04-24 | ||
| JP2008221521A JP5008205B2 (ja) | 2001-04-24 | 2008-08-29 | 経口投与剤及び経口投与剤保持体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002584964A Division JP4267926B2 (ja) | 2001-04-24 | 2002-04-19 | 経口投与剤及び経口投与剤保持体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011273769A Division JP2012051951A (ja) | 2001-04-24 | 2011-12-14 | 経口投与剤及び経口投与剤保持体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009007379A JP2009007379A (ja) | 2009-01-15 |
| JP2009007379A5 true JP2009007379A5 (https=) | 2011-01-13 |
| JP5008205B2 JP5008205B2 (ja) | 2012-08-22 |
Family
ID=18974956
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002584964A Expired - Fee Related JP4267926B2 (ja) | 2001-04-24 | 2002-04-19 | 経口投与剤及び経口投与剤保持体 |
| JP2008221521A Expired - Fee Related JP5008205B2 (ja) | 2001-04-24 | 2008-08-29 | 経口投与剤及び経口投与剤保持体 |
| JP2011273769A Pending JP2012051951A (ja) | 2001-04-24 | 2011-12-14 | 経口投与剤及び経口投与剤保持体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002584964A Expired - Fee Related JP4267926B2 (ja) | 2001-04-24 | 2002-04-19 | 経口投与剤及び経口投与剤保持体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011273769A Pending JP2012051951A (ja) | 2001-04-24 | 2011-12-14 | 経口投与剤及び経口投与剤保持体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20080254102A9 (https=) |
| EP (1) | EP1391212A4 (https=) |
| JP (3) | JP4267926B2 (https=) |
| KR (1) | KR100890180B1 (https=) |
| CN (2) | CN1462194B (https=) |
| AU (1) | AU2002255267B2 (https=) |
| CA (1) | CA2445347C (https=) |
| TW (1) | TWI232755B (https=) |
| WO (1) | WO2002087622A1 (https=) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19646392A1 (de) | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
| US8268333B2 (en) | 2001-04-24 | 2012-09-18 | Lintec Corporation | Orally administered agent and an orally administered agent/supporting substrate complex |
| JP4993652B2 (ja) * | 2004-03-31 | 2012-08-08 | リンテック株式会社 | 経口投与剤 |
| CA2445347C (en) * | 2001-04-24 | 2011-09-27 | Lintec Corporation | An orally administered agent and an orally administered agent/supporting substrate complex |
| AU2003302589A1 (en) * | 2002-12-02 | 2004-06-23 | Kyukyu Pharmaceutical Co., Ltd. | Method for producing orally administrable edible agent of laminate film form and pressure bonding apparatus of the agent. |
| US8469036B2 (en) | 2003-11-07 | 2013-06-25 | U.S. Smokeless Tobacco Company Llc | Tobacco compositions |
| US8627828B2 (en) | 2003-11-07 | 2014-01-14 | U.S. Smokeless Tobacco Company Llc | Tobacco compositions |
| JP2005298471A (ja) * | 2004-03-17 | 2005-10-27 | Lintec Corp | 薬剤の製造方法 |
| CN100455282C (zh) * | 2004-03-17 | 2009-01-28 | 琳得科株式会社 | 药剂的制造方法 |
| JP2005289867A (ja) * | 2004-03-31 | 2005-10-20 | Lintec Corp | 経口投与剤 |
| JP4547994B2 (ja) * | 2004-06-02 | 2010-09-22 | 救急薬品工業株式会社 | 塊状物質含有積層フィルム状の可食性口腔内投与剤の製造方法および塊状物質含有積層フィルム状の可食性口腔内投与剤 |
| JP4587785B2 (ja) * | 2004-11-12 | 2010-11-24 | リンテック株式会社 | 経口投与剤 |
| ES2540929T3 (es) * | 2005-02-01 | 2015-07-14 | Emisphere Technologies, Inc. | Sistema de administración de retención gástrica y liberación controlada |
| JP2006321792A (ja) * | 2005-04-18 | 2006-11-30 | Showa Denko Kk | 含水ゲル体及びその製造方法 |
| JP2007070344A (ja) * | 2005-08-11 | 2007-03-22 | Tsukioka:Kk | 内服薬 |
| JP4860312B2 (ja) * | 2006-03-22 | 2012-01-25 | リンテック株式会社 | 経口投与剤 |
| JP4953673B2 (ja) * | 2006-03-22 | 2012-06-13 | リンテック株式会社 | 経口投与剤 |
| US20090110715A1 (en) * | 2006-05-10 | 2009-04-30 | Kureha Corporation | Edible film Package Having Product for Oral Intake Enclosed Therein |
| JP5525678B2 (ja) * | 2006-08-04 | 2014-06-18 | リンテック株式会社 | 経口投与剤 |
| US8303741B2 (en) | 2007-03-30 | 2012-11-06 | Lintec Corporation | Process for producing preparation for oral administration |
| WO2008126488A1 (ja) | 2007-03-30 | 2008-10-23 | Lintec Corporation | 経口投与剤およびその製造方法 |
| CN101069742B (zh) * | 2007-06-06 | 2010-09-15 | 上海丽珠制药有限公司 | 一种胰激肽原酶片剂及其制备方法 |
| JP5435853B2 (ja) * | 2007-09-28 | 2014-03-05 | 興和株式会社 | 塩酸フェニレフリン含有速溶性フィルム製剤及びその製造方法 |
| AU2008305243B2 (en) * | 2007-09-28 | 2013-09-12 | Lintec Corporation | Medicinal preparation for oral administration |
| CN101883559B (zh) * | 2007-12-06 | 2011-12-28 | 琳得科株式会社 | 可食性薄膜 |
| EP2249802B1 (en) * | 2008-02-06 | 2013-01-16 | University of East Anglia | Composition and method for assisting swallowing |
| CA2719921A1 (en) * | 2008-03-28 | 2009-10-01 | Lintec Corporation | Orally-administered agent |
| TWI441659B (zh) * | 2008-09-29 | 2014-06-21 | Lintec Corp | Oral administration |
| JPWO2010110320A1 (ja) | 2009-03-25 | 2012-10-04 | リンテック株式会社 | 固形製剤 |
| JPWO2010110322A1 (ja) * | 2009-03-25 | 2012-10-04 | リンテック株式会社 | 固形製剤 |
| AU2010228257A1 (en) | 2009-03-25 | 2011-09-29 | Aska Pharmaceutical Co., Ltd. | Adhesion preventing composition, solid preparation and method for producing same |
| JP2011143153A (ja) * | 2010-01-18 | 2011-07-28 | Tsukioka:Kk | フィルムパック |
| AR080077A1 (es) | 2010-01-29 | 2012-03-14 | Colgate Palmolive Co | Tira dental para la administracion de tratamiento por la via oral |
| KR20130029758A (ko) | 2010-03-03 | 2013-03-25 | 코와 가부시키가이샤 | 불쾌한 맛을 갖는 약물을 함유하는 필름 제제 |
| JPWO2011118454A1 (ja) | 2010-03-23 | 2013-07-04 | リンテック株式会社 | 固形製剤 |
| JPWO2011118453A1 (ja) | 2010-03-23 | 2013-07-04 | リンテック株式会社 | 固形製剤 |
| KR101767288B1 (ko) | 2010-03-31 | 2017-08-10 | 모찌다 세이야쿠 가부시끼가이샤 | 복용 용이성 고형 제제 |
| MY158722A (en) * | 2010-07-29 | 2016-11-15 | Santen Pharmaceutical Co Ltd | "drug support body, and method for producing same" |
| CA2777428A1 (en) | 2011-05-20 | 2012-11-20 | Nitto Denko Corporation | Edible jelly-form composition, jelly-form preparation and method for producing jelly-form preparation |
| WO2013046453A1 (ja) | 2011-09-30 | 2013-04-04 | 持田製薬株式会社 | 易服用性固形製剤 |
| JP2013095687A (ja) * | 2011-10-31 | 2013-05-20 | Tsukioka Film Pharma Co Ltd | 口腔内貼付薬 |
| JP5318181B2 (ja) * | 2011-11-17 | 2013-10-16 | リンテック株式会社 | 経口投与剤 |
| US9452135B2 (en) | 2012-03-20 | 2016-09-27 | Particle Dynamics International, Llc | Gelling agent-based dosage form |
| KR102008417B1 (ko) * | 2012-12-04 | 2019-08-08 | 롯데정밀화학 주식회사 | 적층 필름 및 필름 적층방법 |
| CA2935191C (en) | 2013-12-31 | 2021-11-09 | Johnson & Johnson Consumer Inc. | Process for forming a shaped film product |
| KR102240525B1 (ko) * | 2013-12-31 | 2021-04-16 | 존슨 앤드 존슨 컨수머 인코포레이티드 | 다층의 형상화된 필름을 형성하기 위한 방법 |
| US20210000754A1 (en) * | 2019-07-02 | 2021-01-07 | Clifford T. Rowley | Transdermal patch providing improved permeability and composition |
| US12357578B2 (en) * | 2020-10-23 | 2025-07-15 | Appco Pharma Llc | Ibuprofen and famotidine tablet |
| DE102021130950A1 (de) * | 2021-11-25 | 2023-05-25 | Lts Lohmann Therapie-Systeme Ag. | Applikationshilfe |
| KR20250012498A (ko) * | 2022-05-23 | 2025-01-24 | 교와 야쿠힝 고교 가부시키가이샤 | 겔 피막 및 경구 고형 조성물 |
| WO2026062705A1 (en) | 2024-09-23 | 2026-03-26 | Troikaa Pharmaceuticals Limited | Oromucosal liquid compositions of betahistine or its pharmaceutically acceptable salt(s) and processes for preparation thereof |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2513852A (en) * | 1946-12-26 | 1950-07-04 | Alfonso M Donofrio | Method for encapsulating |
| GB1510857A (en) * | 1974-09-13 | 1978-05-17 | Kernforschungsanlage Juelich | Method of separating particles of nuclear fuel ans/or breeder material from a first liquid and introducing them into a second liquid |
| JPS5154917A (ja) * | 1974-11-01 | 1976-05-14 | Toppan Printing Co Ltd | Seizaihoho |
| JPS5513383Y2 (https=) * | 1975-02-21 | 1980-03-26 | ||
| JPS6168415A (ja) * | 1984-09-11 | 1986-04-08 | Toyobo Co Ltd | 口腔粘膜適用口臭除去剤 |
| JPS61280423A (ja) * | 1985-06-05 | 1986-12-11 | Kiyuukiyuu Yakuhin Kogyo Kk | 口腔内粘膜貼付剤 |
| ATE59289T1 (de) * | 1985-10-09 | 1991-01-15 | Desitin Arzneimittel Gmbh | Verfahren zur herstellung einer darreichungsund dosierungsform fuer arzneimittel-wirkstoffe, reagentien oder andere wirkstoffe. |
| US4712460A (en) | 1985-11-18 | 1987-12-15 | Biotrack, Inc. | Integrated drug dosage form and metering system |
| JPS62207208A (ja) * | 1986-03-07 | 1987-09-11 | Teijin Ltd | 経口フイルム状徐放性製剤 |
| US4855142A (en) | 1987-02-27 | 1989-08-08 | Ciba-Geigy Corporation | Pharmaceutical plaster |
| IE64726B1 (en) * | 1987-11-20 | 1995-08-23 | Elan Corp Plc | Pharmaceutical formulations for preventing drug tolerance |
| DE3827561C1 (https=) * | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
| JP2656338B2 (ja) * | 1989-01-31 | 1997-09-24 | 日東電工株式会社 | 口腔粘膜貼付製剤 |
| DE4018247A1 (de) | 1990-06-07 | 1991-12-12 | Lohmann Therapie Syst Lts | Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen |
| JPH05124954A (ja) | 1991-10-29 | 1993-05-21 | Mitsubishi Kasei Corp | シート状固形薬剤組成物 |
| JPH069375A (ja) * | 1992-04-10 | 1994-01-18 | Takeda Chem Ind Ltd | 分割可能な連結錠剤 |
| JPH05310561A (ja) | 1992-04-27 | 1993-11-22 | Lion Corp | 口腔内適用基剤及び口腔内適用製剤 |
| US5744155A (en) * | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
| GB9402203D0 (en) * | 1994-02-04 | 1994-03-30 | Smithkline Beecham Plc | Pharmaceutical formulation |
| DE4419824A1 (de) * | 1994-06-07 | 1995-12-14 | Lohmann Therapie Syst Lts | Volumen-expandierbares, als Wirkstoffträger insbesondere zur oralen Anwendung geeignete flächige Anwendungsform |
| US5824339A (en) * | 1995-09-08 | 1998-10-20 | Takeda Chemical Industries, Ltd | Effervescent composition and its production |
| DE19539361A1 (de) * | 1995-10-23 | 1997-04-24 | Basf Ag | Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung |
| US5766620A (en) * | 1995-10-23 | 1998-06-16 | Theratech, Inc. | Buccal delivery of glucagon-like insulinotropic peptides |
| JP2791317B2 (ja) * | 1995-12-26 | 1998-08-27 | 株式会社三和化学研究所 | 多層フィルム製剤 |
| JPH09276374A (ja) * | 1996-04-08 | 1997-10-28 | Yomisu:Kk | 2度ごっくんこ |
| JPH1024091A (ja) * | 1996-07-10 | 1998-01-27 | Noboru Mori | 粒体物等のためのカウンティングスプーン |
| CA2262595C (en) * | 1996-08-15 | 2005-10-18 | Losan Pharma Gmbh | Easy to swallow oral medicament composition |
| FR2762513B1 (fr) * | 1997-04-23 | 2003-08-22 | Permatec Pharma Ag | Comprimes bioadhesifs |
| JP2000024089A (ja) * | 1998-07-12 | 2000-01-25 | Yutaka Yoshino | 散剤投与具 |
| JP2000119128A (ja) * | 1998-10-13 | 2000-04-25 | Nitto Denko Corp | 化粧用ゲルシート及びその製造方法 |
| US6797283B1 (en) * | 1998-12-23 | 2004-09-28 | Alza Corporation | Gastric retention dosage form having multiple layers |
| CN100391438C (zh) | 1999-09-14 | 2008-06-04 | 史密丝克莱恩比彻姆公司 | 制备水性包被小球粒的方法 |
| GB0027357D0 (en) * | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
| CA2445347C (en) * | 2001-04-24 | 2011-09-27 | Lintec Corporation | An orally administered agent and an orally administered agent/supporting substrate complex |
| ATE398465T1 (de) * | 2001-11-16 | 2008-07-15 | Givaudan Sa | Essbare folie |
-
2002
- 2002-04-19 CA CA2445347A patent/CA2445347C/en not_active Expired - Fee Related
- 2002-04-19 AU AU2002255267A patent/AU2002255267B2/en not_active Ceased
- 2002-04-19 CN CN028013735A patent/CN1462194B/zh not_active Expired - Fee Related
- 2002-04-19 KR KR1020027017540A patent/KR100890180B1/ko not_active Expired - Fee Related
- 2002-04-19 JP JP2002584964A patent/JP4267926B2/ja not_active Expired - Fee Related
- 2002-04-19 EP EP02724622A patent/EP1391212A4/en not_active Withdrawn
- 2002-04-19 CN CN2010101158635A patent/CN101785863B/zh not_active Expired - Fee Related
- 2002-04-19 WO PCT/JP2002/003920 patent/WO2002087622A1/ja not_active Ceased
- 2002-04-23 TW TW091108355A patent/TWI232755B/zh not_active IP Right Cessation
-
2003
- 2003-10-23 US US10/690,811 patent/US20080254102A9/en not_active Abandoned
-
2008
- 2008-08-29 JP JP2008221521A patent/JP5008205B2/ja not_active Expired - Fee Related
-
2011
- 2011-12-14 JP JP2011273769A patent/JP2012051951A/ja active Pending
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