JP2008521861A5 - - Google Patents

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Publication number
JP2008521861A5
JP2008521861A5 JP2007543838A JP2007543838A JP2008521861A5 JP 2008521861 A5 JP2008521861 A5 JP 2008521861A5 JP 2007543838 A JP2007543838 A JP 2007543838A JP 2007543838 A JP2007543838 A JP 2007543838A JP 2008521861 A5 JP2008521861 A5 JP 2008521861A5
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JP
Japan
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compound
formula
group
alkyl
hydrogen
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JP2007543838A
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English (en)
Japanese (ja)
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JP2008521861A (ja
JP5164574B2 (ja
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Priority claimed from DE102004058337A external-priority patent/DE102004058337A1/de
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Publication of JP2008521861A5 publication Critical patent/JP2008521861A5/ja
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Publication of JP5164574B2 publication Critical patent/JP5164574B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007543838A 2004-12-02 2005-11-29 環付加ピペラジン−2−オン誘導体の製造方法及び前記方法の中間体 Expired - Lifetime JP5164574B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004058337A DE102004058337A1 (de) 2004-12-02 2004-12-02 Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
DE102004058337.4 2004-12-02
PCT/EP2005/056291 WO2006058876A1 (de) 2004-12-02 2005-11-29 Verfahren zur herstellung von annelierten piperazin-2-on derivaten sowie zwischenprodukte des verfahrens

Publications (3)

Publication Number Publication Date
JP2008521861A JP2008521861A (ja) 2008-06-26
JP2008521861A5 true JP2008521861A5 (OSRAM) 2009-01-22
JP5164574B2 JP5164574B2 (ja) 2013-03-21

Family

ID=35923724

Family Applications (1)

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JP2007543838A Expired - Lifetime JP5164574B2 (ja) 2004-12-02 2005-11-29 環付加ピペラジン−2−オン誘導体の製造方法及び前記方法の中間体

Country Status (34)

Country Link
US (9) US7238807B2 (OSRAM)
EP (2) EP1819706B1 (OSRAM)
JP (1) JP5164574B2 (OSRAM)
KR (2) KR101395591B1 (OSRAM)
CN (3) CN101065381B (OSRAM)
AR (1) AR053100A1 (OSRAM)
AU (1) AU2005311308B2 (OSRAM)
BR (1) BRPI0518601A2 (OSRAM)
CA (1) CA2588857C (OSRAM)
CL (1) CL2013002895A1 (OSRAM)
CY (1) CY1113625T1 (OSRAM)
DE (1) DE102004058337A1 (OSRAM)
DK (2) DK2436685T3 (OSRAM)
EA (1) EA012624B1 (OSRAM)
ES (2) ES2548680T3 (OSRAM)
HR (1) HRP20120980T1 (OSRAM)
HU (1) HUE027689T2 (OSRAM)
IL (1) IL183568A (OSRAM)
ME (1) ME01470B (OSRAM)
MX (1) MX2007006549A (OSRAM)
MY (1) MY147459A (OSRAM)
NO (1) NO20072283L (OSRAM)
NZ (1) NZ556182A (OSRAM)
PE (2) PE20090488A1 (OSRAM)
PL (2) PL2436685T3 (OSRAM)
PT (1) PT1819706E (OSRAM)
RS (1) RS52533B (OSRAM)
SG (2) SG141461A1 (OSRAM)
SI (1) SI1819706T1 (OSRAM)
TW (1) TWI362391B (OSRAM)
UA (1) UA89390C2 (OSRAM)
UY (1) UY29233A1 (OSRAM)
WO (1) WO2006058876A1 (OSRAM)
ZA (1) ZA200703368B (OSRAM)

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EP1630163A1 (de) * 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1632493A1 (de) * 2004-08-25 2006-03-08 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
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EP3098223A1 (en) * 2007-08-03 2016-11-30 Boehringer Ingelheim International GmbH Crystalline form of a dihydropteridione derivative
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CN102020643A (zh) 2009-09-22 2011-04-20 上海恒瑞医药有限公司 二氢喋啶酮类衍生物、其制备方法及其在医药上的应用
SG179206A1 (en) 2009-09-25 2012-04-27 Vertex Pharma Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
NZ599342A (en) 2009-09-25 2014-04-30 Vertex Pharma Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
EP2678342B1 (en) 2011-02-25 2015-01-07 Takeda Pharmaceutical Company Limited N-substituted oxazinopteridines and oxazinopteridinones
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
UY34893A (es) 2012-07-10 2014-02-28 Takeda Pharmaceutical Derivados de azaindol
WO2015011236A1 (en) 2013-07-26 2015-01-29 Boehringer Ingelheim International Gmbh Treatment of myelodysplastic syndrome
AR099052A1 (es) 2014-01-09 2016-06-29 Takeda Pharmaceuticals Co Derivados de azaindol
US9867831B2 (en) 2014-10-01 2018-01-16 Boehringer Ingelheim International Gmbh Combination treatment of acute myeloid leukemia and myelodysplastic syndrome

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US20060058311A1 (en) 2004-08-14 2006-03-16 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation
EP1632493A1 (de) * 2004-08-25 2006-03-08 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1630163A1 (de) * 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
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DE102004058337A1 (de) * 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
JP2009503014A (ja) 2005-08-03 2009-01-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器系疾患の治療におけるジヒドロプテリジノン
US7439358B2 (en) * 2006-02-08 2008-10-21 Boehringer Ingelheim International Gmbh Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
CN101437795A (zh) 2006-03-07 2009-05-20 阿斯利康(瑞典)有限公司 哌啶衍生物,制备它们的方法,它们作为治疗剂的用途和含有它们的药物组合物
EP3098223A1 (en) 2007-08-03 2016-11-30 Boehringer Ingelheim International GmbH Crystalline form of a dihydropteridione derivative

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