JP2008500385A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008500385A5 JP2008500385A5 JP2007521014A JP2007521014A JP2008500385A5 JP 2008500385 A5 JP2008500385 A5 JP 2008500385A5 JP 2007521014 A JP2007521014 A JP 2007521014A JP 2007521014 A JP2007521014 A JP 2007521014A JP 2008500385 A5 JP2008500385 A5 JP 2008500385A5
- Authority
- JP
- Japan
- Prior art keywords
- chloronaphthalen
- sulfonyl
- hydroxypropanoyl
- salt
- piperidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004152000 | 2004-05-21 | ||
| PCT/JP2005/009711 WO2005113504A1 (en) | 2004-05-21 | 2005-05-20 | Cyclic amide derivatives, and their production and use as antithrombotic agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008006003A Division JP4362535B2 (ja) | 2004-05-21 | 2008-01-15 | 環状アミド誘導体、その製造法および抗血栓剤としての用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008500385A JP2008500385A (ja) | 2008-01-10 |
| JP2008500385A5 true JP2008500385A5 (cg-RX-API-DMAC7.html) | 2008-02-28 |
| JP4129047B2 JP4129047B2 (ja) | 2008-07-30 |
Family
ID=34968275
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007521014A Expired - Fee Related JP4129047B2 (ja) | 2004-05-21 | 2005-05-20 | 環状アミド誘導体、その製造法および抗血栓剤としての用途 |
| JP2008006003A Expired - Fee Related JP4362535B2 (ja) | 2004-05-21 | 2008-01-15 | 環状アミド誘導体、その製造法および抗血栓剤としての用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008006003A Expired - Fee Related JP4362535B2 (ja) | 2004-05-21 | 2008-01-15 | 環状アミド誘導体、その製造法および抗血栓剤としての用途 |
Country Status (26)
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2416384A1 (en) * | 2000-07-17 | 2003-01-16 | Takeda Chemical Industries, Ltd. | Sulfone derivatives, their production and use |
| US20070004736A1 (en) * | 2002-11-22 | 2007-01-04 | Keiji Kubo | Imidazole derivative, process for producing the same, and use |
| TWI396686B (zh) * | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| WO2007114861A2 (en) * | 2005-11-28 | 2007-10-11 | Zymogenetics, Inc. | Il-21 receptor antagonists |
| US20110045028A1 (en) * | 2006-11-30 | 2011-02-24 | Takeda Pharmaceutical Company Limited | Sustained release preparation |
| UY32126A (es) | 2008-09-25 | 2010-04-30 | Takeda Pharmaceutical | Composición farmacéutica sólida |
| WO2010050445A1 (ja) | 2008-10-27 | 2010-05-06 | 武田薬品工業株式会社 | 二環性化合物 |
| US8557805B2 (en) | 2008-12-29 | 2013-10-15 | Takeda Pharmaceutical Company Limited | Fused ring compound and use thereof |
| US20100190747A1 (en) | 2009-01-27 | 2010-07-29 | Hideo Suzuki | Fused ring compound and use thereof |
| PE20120315A1 (es) | 2009-04-30 | 2012-04-07 | Takeda Pharmaceutical | Una composicion farmaceutica que comprende candesartan, candesartan cilexetil, o azilsartan, combinado con amlodipino |
| WO2010143733A1 (en) | 2009-06-09 | 2010-12-16 | Takeda Pharmaceutical Company Limited | Novel fused cyclic compound and use thereof |
| EA201270204A1 (ru) | 2009-07-28 | 2012-08-30 | Такеда Фармасьютикал Компани Лимитед | Таблетка |
| US8221489B2 (en) * | 2009-08-20 | 2012-07-17 | Stentys | Device and method for treating a body lumen |
| WO2011136385A1 (en) | 2010-04-27 | 2011-11-03 | Takeda Pharmaceutical Company Limited | Bicyclic compound derivatives and their use as acc inhibitors. |
| US9018374B2 (en) | 2010-06-16 | 2015-04-28 | Takeda Pharmaceutical Company Limited | Crystal of amide compound |
| CA2806258A1 (en) | 2010-07-23 | 2012-01-26 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound and application thereof |
| EP2617726A4 (en) | 2010-09-17 | 2014-05-14 | Takeda Pharmaceutical | DIABETES THERAPEUTIC |
| ES2536319T3 (es) | 2010-11-30 | 2015-05-22 | Takeda Pharmaceutical Company Limited | Compuestos bicíclicos como inhibidores de acetil-CoA carboxilasa (ACC) |
| JP5945545B2 (ja) | 2011-02-17 | 2016-07-05 | 武田薬品工業株式会社 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
| US9133129B2 (en) | 2011-10-24 | 2015-09-15 | Takeda Pharmaceutical Company Limited | Bicyclic compound |
| US9365540B2 (en) | 2012-01-12 | 2016-06-14 | Takeda Pharmaceutical Company Limited | Benzimidazole derivatives as MCH receptor antagonists |
| WO2013122028A1 (ja) | 2012-02-13 | 2013-08-22 | 武田薬品工業株式会社 | 芳香環化合物 |
| JP6121339B2 (ja) | 2012-02-13 | 2017-04-26 | 武田薬品工業株式会社 | 芳香環化合物 |
| CA2864068A1 (en) | 2012-02-15 | 2013-08-22 | Takeda Pharmaceutical Company Limited | Tablet comprising 1-(4-methoxybutyl)-n-(2-methylpropyl)-n-[(3s,5r)-5-(morpholin-4-ylcarbonyl)piperidin-3-yl]-1h-benzimidazole-2-carboxamide or a salt thereof |
| US9238639B2 (en) | 2012-02-24 | 2016-01-19 | Takeda Pharmaceutical Company Limited | Aromatic ring compound |
| CA2868713A1 (en) | 2012-03-29 | 2013-10-03 | Takeda Pharmaceutical Company Limited | Aromatic ring compound |
| US9505772B2 (en) | 2012-05-10 | 2016-11-29 | Takeda Pharmaceutical Company Limited | Aromatic ring compound |
| EP2848621A4 (en) | 2012-05-10 | 2016-06-01 | Takeda Pharmaceutical | AROMATIC RING CONNECTION |
| AR092843A1 (es) | 2012-06-05 | 2015-05-06 | Takeda Pharmaceuticals Co | Preparacion solida |
| JP2015127299A (ja) | 2012-07-19 | 2015-07-09 | 武田薬品工業株式会社 | 固形製剤 |
| JPWO2014030743A1 (ja) | 2012-08-24 | 2016-08-08 | 武田薬品工業株式会社 | 複素環化合物 |
| CN103936763B (zh) * | 2013-01-18 | 2017-10-31 | 中国科学院上海药物研究所 | 噁唑烷酮类化合物及其制备方法和用途 |
| JP6247697B2 (ja) | 2013-03-14 | 2017-12-13 | 武田薬品工業株式会社 | スピロアゼチジンイソキサゾール誘導体及びそのｓｓｔｒ５アンタゴニストとしての使用 |
| US10005720B2 (en) | 2013-04-05 | 2018-06-26 | North Carolina Central University | Compounds useful for the treatment of metabolic disorders and synthesis of the same |
| US9199963B2 (en) | 2013-07-09 | 2015-12-01 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| PL3031799T3 (pl) | 2013-08-09 | 2018-09-28 | Takeda Pharmaceutical Company Limited | Związek aromatyczny |
| JO3442B1 (ar) | 2013-10-07 | 2019-10-20 | Takeda Pharmaceuticals Co | مضادات ذات نوع فرعي من مستقبل سوماتوستاتين 5 (sstr5) |
| US9428470B2 (en) | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| US9346776B2 (en) | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
| JP2017529401A (ja) * | 2014-09-26 | 2017-10-05 | チャーンジョウ インシュヨン ファーマシューティカル カンパニー，リミティド | Ｎｓ４ｂ阻害剤としてのベンゾフラン類似体 |
| EP3524596B1 (en) | 2014-12-23 | 2020-09-09 | Crossing S.r.l. | Reagents comprising 2-halo-4,6-dialkoxy-1,3,5-triazines in the presence of amines and their use in a stabilization method. |
| AR111199A1 (es) | 2017-03-31 | 2019-06-12 | Takeda Pharmaceuticals Co | Compuesto aromático agonista de gpr40 |
| JOP20190211A1 (ar) | 2017-03-31 | 2019-09-15 | Takeda Pharmaceuticals Co | ببتيد منشط لمستقبل gip |
| WO2018181847A1 (ja) | 2017-03-31 | 2018-10-04 | 武田薬品工業株式会社 | 芳香環化合物 |
| US11207312B2 (en) | 2017-07-17 | 2021-12-28 | Merck Sharp & Dohme Corp. | Metallo-beta-lactamase inhibitors and methods of use thereof |
| MX2020009950A (es) | 2018-03-23 | 2021-04-28 | Carmot Therapeutics Inc | Moduladores de receptores acoplados a proteina g. |
| TW202024028A (zh) | 2018-08-27 | 2020-07-01 | 日商思可海雅藥品股份有限公司 | 苯甲酸酯化合物 |
| US12122815B2 (en) | 2018-09-24 | 2024-10-22 | Takeda Pharmaceutical Company Limited | GIP receptor agonist peptide compounds and uses thereof |
| EP3856339A1 (en) | 2018-09-24 | 2021-08-04 | Takeda Pharmaceutical Company Limited | Gip receptor agonist peptide compounds and uses thereof |
| HRP20241159T1 (hr) | 2020-02-07 | 2024-12-06 | Gasherbrum Bio, Inc. | Heterociklički agonisti za glp-1 |
| CN115916812A (zh) | 2020-03-25 | 2023-04-04 | 武田药品工业株式会社 | Gip受体激动剂肽化合物及其用途 |
| CN115335395A (zh) | 2020-03-25 | 2022-11-11 | 武田药品工业株式会社 | Gip受体激动剂肽化合物的qd给药及其用途 |
| TW202206429A (zh) | 2020-04-29 | 2022-02-16 | 美商迦舒布魯姆生物有限公司 | 雜環ｇｌｐ—１促效劑 |
| US12281149B2 (en) | 2021-05-13 | 2025-04-22 | Carmot Therapeutics, Inc. | Modulators of G-protein coupled receptors |
| JP2025509281A (ja) | 2022-03-09 | 2025-04-11 | ガシャーブラム・バイオ・インコーポレイテッド | ヘテロ環式ｇｌｐ－１アゴニスト |
| US20250206757A1 (en) | 2022-03-21 | 2025-06-26 | Gasherbrum Bio, Inc. | 5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes |
| US20250250269A1 (en) | 2022-04-14 | 2025-08-07 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| TW202435857A (zh) | 2022-12-15 | 2024-09-16 | 美商迦舒布魯姆生物有限公司 | 具有glp-1促效劑活性之化合物之鹽及固體形式 |
| WO2024131869A1 (en) | 2022-12-22 | 2024-06-27 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| JP2026501286A (ja) | 2022-12-22 | 2026-01-14 | ガシャーブラム・バイオ・インコーポレイテッド | ヘテロ環式ｇｌｐ－１アゴニスト |
| CN120957993A (zh) | 2023-02-16 | 2025-11-14 | 加舒布鲁姆生物公司 | 杂环glp-1激动剂 |
| EP4735456A1 (en) | 2023-06-30 | 2026-05-06 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| AR133240A1 (es) | 2023-07-13 | 2025-09-10 | Aconcagua Bio Inc | Compuestos, composiciones y métodos |
| TW202519220A (zh) | 2023-07-13 | 2025-05-16 | 美商雅空嘉閣生物公司 | 化合物、組合物及方法 |
| WO2025045208A1 (en) | 2023-08-31 | 2025-03-06 | Gasherbrum Bio, Inc. | Heteroaryl-heterocycloalkyl-based glp-1 agonists |
| WO2025137307A1 (en) | 2023-12-20 | 2025-06-26 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2025154020A1 (en) | 2024-01-19 | 2025-07-24 | Takeda Pharmaceutical Company Limited | Improved gip receptor agonist peptide compounds and uses thereof |
| WO2025154021A1 (en) | 2024-01-19 | 2025-07-24 | Takeda Pharmaceutical Company Limited | Improved gip receptor agonist peptide compounds and uses thereof |
| WO2025171341A2 (en) | 2024-02-08 | 2025-08-14 | Aconcagua Bio, Inc. | Compounds and compositions for treating conditions associated with calcitonin receptor and/or amylin receptor activity |
| WO2025171340A1 (en) | 2024-02-08 | 2025-08-14 | Aconcagua Bio, Inc. | The treatment of calcitonin- and/or amylin-receptor associated conditions |
| TW202600132A (zh) | 2024-03-08 | 2026-01-01 | 美商安尼波那生物公司 | 用於治療肥胖症及提高減重之方法 |
| WO2026041075A1 (en) | 2024-08-21 | 2026-02-26 | Gasherbrum Bio, Inc. | Gpl-1 agonists |
| WO2026051998A1 (en) | 2024-09-04 | 2026-03-12 | Aconcagua Bio, Inc. | Compounds, compositions, and methods |
Family Cites Families (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US270488A (en) * | 1883-01-09 | Drilling apparatus | ||
| US2201270A (en) * | 1936-04-17 | 1940-05-21 | Mcintyre John Taylor | Apparatus for allaying dust from rock drills |
| US2946565A (en) * | 1953-06-16 | 1960-07-26 | Jersey Prod Res Co | Combination drilling and testing process |
| US2849214A (en) * | 1954-09-02 | 1958-08-26 | Gulf Research Development Co | Borehole drilling apparatus for preventing lost circulation |
| US3497020A (en) * | 1968-05-20 | 1970-02-24 | Archer W Kammerer Jr | System for reducing hydrostatic pressure on formations |
| JPS5011391B1 (cg-RX-API-DMAC7.html) * | 1970-07-21 | 1975-04-30 | ||
| SE355840B (cg-RX-API-DMAC7.html) * | 1971-09-08 | 1973-05-07 | Atlas Copco Ab | |
| FR2228301B1 (cg-RX-API-DMAC7.html) | 1973-05-03 | 1977-10-14 | Ibm | |
| US4147786A (en) | 1976-02-02 | 1979-04-03 | Ciba-Geigy Corporation | 1-Indolylalkyl-3-or 4-trimethyleneurido-piperidines |
| US4264599A (en) | 1977-07-08 | 1981-04-28 | Ciba-Geigy Corporation | Piperidino-propanols |
| EP0000485A1 (de) | 1977-07-08 | 1979-02-07 | Ciba-Geigy Ag | Piperidino-propanole, ihre Herstellung und pharmazeutische Präparate die diese enthalten |
| US4329348A (en) | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| US4630691A (en) * | 1983-05-19 | 1986-12-23 | Hooper David W | Annulus bypass peripheral nozzle jet pump pressure differential drilling tool and method for well drilling |
| US4534426A (en) * | 1983-08-24 | 1985-08-13 | Unique Oil Tools, Inc. | Packer weighted and pressure differential method and apparatus for Big Hole drilling |
| US4567954A (en) * | 1983-12-02 | 1986-02-04 | Norton Christensen, Inc. | Replaceable nozzles for insertion into a drilling bit formed by powder metallurgical techniques and a method for manufacturing the same |
| US4695575A (en) | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
| ZA928276B (en) | 1991-10-31 | 1993-05-06 | Daiichi Seiyaku Co | Aromatic amidine derivates and salts thereof. |
| US5902272A (en) | 1992-01-07 | 1999-05-11 | Arthrocare Corporation | Planar ablation probe and method for electrosurgical cutting and ablation |
| US5595872A (en) | 1992-03-06 | 1997-01-21 | Bristol-Myers Squibb Company | Nucleic acids encoding microsomal trigyceride transfer protein |
| HU218419B (hu) | 1992-03-06 | 2000-08-28 | E.R. Squibb And Sons, Inc. | Mikroszomális triglicerid transzfer protein (MTP) nagy molekulatömegű alegységének rekombináns úton történő előállítására és a protein és inhibitorainak kimutatására szolgáló eljárások |
| US5355967A (en) * | 1992-10-30 | 1994-10-18 | Union Oil Company Of California | Underbalance jet pump drilling method |
| GB9321557D0 (en) | 1992-11-03 | 1993-12-08 | Zeneca Ltd | Carboxamide derivatives |
| GB9312806D0 (en) | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| GB9317104D0 (en) | 1993-08-17 | 1993-09-29 | Zeneca Ltd | Therapeutic heterocycles |
| TW394760B (en) | 1993-09-07 | 2000-06-21 | Hoffmann La Roche | Novel Carboxamides, process for their preparation and pharmaceutical composition containing the same |
| IL112795A (en) * | 1994-03-04 | 2001-01-28 | Astrazeneca Ab | Peptide derivatives as antithrombic agents their preparation and pharmaceutical compositions containing them |
| US5456326A (en) * | 1994-04-18 | 1995-10-10 | Exxon Production Research Company | Apparatus and method for installing open-ended tubular members axially into the earth |
| IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| JP2002515008A (ja) | 1994-10-27 | 2002-05-21 | メルク エンド カンパニー インコーポレーテッド | ムスカリン・アンタゴニスト |
| ES2193202T3 (es) | 1994-12-02 | 2003-11-01 | Yamanouchi Pharma Co Ltd | Nuevo derivado de amidinonaftilo o sal de este. |
| GB9508786D0 (en) | 1995-04-29 | 1995-06-21 | Zeneca Ltd | Substituted heterocycles |
| FI974368A7 (fi) | 1995-05-29 | 1997-11-28 | Pfizer | Kasvuhormonin vapautumista edistäviä dipeptidejä |
| US5612353A (en) | 1995-06-07 | 1997-03-18 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds |
| US5849759A (en) | 1995-12-08 | 1998-12-15 | Berlex Laboratories, Inc. | Naphthyl-substituted benzimidazole derivatives as anti-coagulants |
| GB9602294D0 (en) | 1996-02-05 | 1996-04-03 | Zeneca Ltd | Heterocyclic compounds |
| AU754936B2 (en) | 1996-11-27 | 2002-11-28 | Aventis Pharmaceuticals Inc. | Pharmaceutical composition comprising a compound having anti-Xa activity and a platelet aggregation antagonist compound |
| WO1998054164A1 (en) | 1997-05-30 | 1998-12-03 | Takeda Chemical Industries, Ltd. | Sulfonamide derivatives, their production and use |
| FR2764511B1 (fr) | 1997-06-13 | 2000-09-08 | Sanofi Sa | Compositions pour le traitement et la prevention de la thrombose arterielle et utilisation d'un inhibiteur du facteur xa seul et/ou en combinaison avec un antiagregant plaquettaire |
| GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
| NZ504324A (en) | 1997-11-20 | 2002-02-01 | Teijin Ltd | Biphenylamidine derivatives and pharmaceutical compositions thereof; which can be useful as anticoagulant inhibitors, and thrombus or embolus preventing agents |
| IL135408A0 (en) | 1997-11-21 | 2001-05-20 | Schering Corp | Substituted oximes as neurokinin antagonists |
| AU1692399A (en) | 1997-12-26 | 1999-07-19 | Mochida Pharmaceutical Co., Ltd. | Aromatic compounds having cyclic amino or salts thereof |
| WO1999040075A1 (en) | 1998-02-05 | 1999-08-12 | Takeda Chemical Industries, Ltd. | Sulfonamide derivatives, process for producing the same and utilization thereof |
| PL343424A1 (en) * | 1998-04-10 | 2001-08-13 | Japan Tobacco Inc | Amidine compounds |
| US6129152A (en) * | 1998-04-29 | 2000-10-10 | Alpine Oil Services Inc. | Rotating bop and method |
| GB9809349D0 (en) | 1998-05-02 | 1998-07-01 | Zeneca Ltd | Heterocyclic derivatives |
| US6423519B1 (en) * | 1998-07-15 | 2002-07-23 | Gpc Biotech Inc. | Compositions and methods for inhibiting fungal growth |
| US6747023B1 (en) | 1998-08-11 | 2004-06-08 | Daiichi Pharmaceutical Co., Ltd. | Sulfonyl derivatives |
| JP2000080046A (ja) | 1998-09-03 | 2000-03-21 | Dai Ichi Seiyaku Co Ltd | 多臓器障害の予防・治療剤 |
| EP1115396A4 (en) | 1998-09-25 | 2002-05-22 | Sunol Molecular Corp | PHARMACEUTICALLY ACTIVE COMPOUNDS, AND METHODS OF USE THEREOF |
| CA2355886C (en) | 1998-12-23 | 2006-10-31 | Schering Corporation | Substituted oximes and hydrazones as neurokinin antagonists |
| US6204265B1 (en) | 1998-12-23 | 2001-03-20 | Schering Corporation | Substituted oximes and hydrazones as neurokinin antagonists |
| US7217714B1 (en) | 1998-12-23 | 2007-05-15 | Agouron Pharmaceuticals, Inc. | CCR5 modulators |
| EP1188755B1 (en) | 1999-06-22 | 2006-05-03 | Takeda Pharmaceutical Company Limited | Acylhydrazine derivatives, process for preparing the same and use thereof |
| TR200103853T2 (tr) | 1999-06-30 | 2002-11-21 | Mochida Pharmaceutical Co., Ltd | Spiro bağlı trisiklik bileşikler. |
| CN1420882A (zh) | 1999-07-28 | 2003-05-28 | 阿温蒂斯药物公司 | 取代的氧代氮杂杂环基化合物 |
| AU7354900A (en) | 1999-09-09 | 2001-04-10 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| US20020052343A1 (en) | 1999-12-15 | 2002-05-02 | Allen Darin Arthur | Salicylamides as serine protease inhibitors |
| US6723091B2 (en) | 2000-02-22 | 2004-04-20 | Gyrus Medical Limited | Tissue resurfacing |
| US6629974B2 (en) | 2000-02-22 | 2003-10-07 | Gyrus Medical Limited | Tissue treatment method |
| AR033517A1 (es) | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
| CA2416384A1 (en) * | 2000-07-17 | 2003-01-16 | Takeda Chemical Industries, Ltd. | Sulfone derivatives, their production and use |
| JP2002201178A (ja) * | 2000-07-17 | 2002-07-16 | Takeda Chem Ind Ltd | スルホン誘導体、その製造法及び用途 |
| US6511973B2 (en) | 2000-08-02 | 2003-01-28 | Bristol-Myers Squibb Co. | Lactam inhibitors of FXa and method |
| US20040082786A1 (en) | 2000-09-29 | 2004-04-29 | Bing-Yan Zhu | Piperazine based inhibitors of factor xa |
| AU2002222328A1 (en) | 2000-10-18 | 2002-04-29 | Gian Franco Bernabei | Method and apparatus for plasma skin resurfacing |
| FR2819511A1 (fr) | 2001-01-18 | 2002-07-19 | Servier Lab | Nouveaux composes azepane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JPWO2002068407A1 (ja) | 2001-02-28 | 2004-06-24 | 山之内製薬株式会社 | ベンゾイミダゾール化合物 |
| DE60224805T2 (de) | 2001-07-26 | 2009-01-22 | Eli Lilly And Co., Indianapolis | 1-glycinyl-4-(1-methylpiperidin-4-yl)piperazine und -piperidine als faktor-xa-antagonisten |
| US6877571B2 (en) * | 2001-09-04 | 2005-04-12 | Sunstone Corporation | Down hole drilling assembly with independent jet pump |
| WO2003022214A2 (en) | 2001-09-06 | 2003-03-20 | Millennium Pharmaceuticals, Inc. | Piperazine and homopiperazine compounds |
| CN104744461A (zh) | 2001-09-21 | 2015-07-01 | 百时美施贵宝公司 | 含有内酰胺的化合物及其衍生物作为Xa因子的抑制剂 |
| WO2003031432A1 (en) * | 2001-10-12 | 2003-04-17 | Novo Nordisk A/S | Substituted piperidines and their use for the treatment of diseases related to the histamine h3 receptor |
| DE10155075A1 (de) | 2001-11-09 | 2003-05-22 | Merck Patent Gmbh | Cyclische Sulfonamide |
| PT1489078E (pt) | 2002-03-28 | 2010-02-24 | Mitsubishi Tanabe Pharma Corp | Derivados de benzofurano |
| TW200307667A (en) | 2002-05-06 | 2003-12-16 | Bristol Myers Squibb Co | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors |
| DE10229070A1 (de) | 2002-06-28 | 2004-01-15 | Merck Patent Gmbh | Phenylderivate 5 |
| US20040006490A1 (en) | 2002-07-08 | 2004-01-08 | Gingrich Mark A. | Prescription data exchange system |
| WO2004031145A2 (en) | 2002-10-02 | 2004-04-15 | Bristol-Myers Squibb Company | Lactam-containing diaminoalkyl, beta-aminoacids, alpha-aminoacids and derivatives thereof as factor xa inhibitors |
| WO2004035579A1 (ja) | 2002-10-15 | 2004-04-29 | Takeda Pharmaceutical Company Limited | イミダゾピリジン誘導体、その製造法および用途 |
| US20070004736A1 (en) | 2002-11-22 | 2007-01-04 | Keiji Kubo | Imidazole derivative, process for producing the same, and use |
| MXPA05008878A (es) | 2003-02-21 | 2005-10-05 | Pfizer | Derivados de aminotiazol sustituidos con cicloalquilo que contiene n y composiciones farmaceuticas para inhibir la proliferacion celular, y metodos para su uso. |
| US6899188B2 (en) * | 2003-03-26 | 2005-05-31 | Sunstone Corporation | Down hole drilling assembly with concentric casing actuated jet pump |
| WO2005087266A1 (en) | 2004-03-05 | 2005-09-22 | Vddi Pharmaceuticals | Combination therapy for inhibition of platelet aggregation |
| TWI396686B (zh) * | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| US7988933B2 (en) | 2006-09-01 | 2011-08-02 | Siemens Healthcare Diagnostics Inc. | Identification system for a clinical sample container |
| KR100906250B1 (ko) | 2006-09-04 | 2009-07-07 | 주식회사 엘지화학 | 바인더로서 고중합도 폴리비닐알콜과 폴리비닐피롤리돈의혼합물을 포함하는 전극 합제 및 이를 포함하는 리튬이차전지 |
-
2005
- 2005-05-19 TW TW094116243A patent/TWI396686B/zh not_active IP Right Cessation
- 2005-05-20 KR KR1020067023942A patent/KR101248637B1/ko not_active Expired - Fee Related
- 2005-05-20 BR BRPI0511186-2A patent/BRPI0511186A/pt not_active Application Discontinuation
- 2005-05-20 MX MXPA06013243A patent/MXPA06013243A/es active IP Right Grant
- 2005-05-20 EP EP10161428.7A patent/EP2208726B1/en not_active Expired - Lifetime
- 2005-05-20 PL PL05743594T patent/PL1748985T3/pl unknown
- 2005-05-20 WO PCT/JP2005/009711 patent/WO2005113504A1/en not_active Ceased
- 2005-05-20 PH PH1/2012/501331A patent/PH12012501331A1/en unknown
- 2005-05-20 RU RU2006145449/04A patent/RU2361861C2/ru not_active IP Right Cessation
- 2005-05-20 SI SI200531321T patent/SI1748985T1/sl unknown
- 2005-05-20 HR HR20110640T patent/HRP20110640T1/hr unknown
- 2005-05-20 MY MYPI20052298A patent/MY154461A/en unknown
- 2005-05-20 NZ NZ550985A patent/NZ550985A/en not_active IP Right Cessation
- 2005-05-20 AU AU2005245298A patent/AU2005245298B2/en not_active Ceased
- 2005-05-20 JP JP2007521014A patent/JP4129047B2/ja not_active Expired - Fee Related
- 2005-05-20 RS RS20110371A patent/RS51925B/sr unknown
- 2005-05-20 CN CN2005800244522A patent/CN1989104B/zh not_active Expired - Fee Related
- 2005-05-20 PT PT05743594T patent/PT1748985E/pt unknown
- 2005-05-20 ES ES05743594T patent/ES2368155T3/es not_active Expired - Lifetime
- 2005-05-20 DK DK05743594.3T patent/DK1748985T3/da active
- 2005-05-20 US US11/596,089 patent/US7745623B2/en not_active Expired - Fee Related
- 2005-05-20 CA CA2567506A patent/CA2567506C/en not_active Expired - Fee Related
- 2005-05-20 EP EP05743594A patent/EP1748985B1/en not_active Expired - Lifetime
- 2005-05-20 CN CN2010105739971A patent/CN102093285B/zh not_active Expired - Fee Related
- 2005-05-20 AT AT05743594T patent/ATE513813T1/de active
-
2006
- 2006-10-26 IL IL178896A patent/IL178896A/en not_active IP Right Cessation
- 2006-12-20 NO NO20065929A patent/NO20065929L/no not_active Application Discontinuation
-
2008
- 2008-01-15 JP JP2008006003A patent/JP4362535B2/ja not_active Expired - Fee Related
- 2008-06-11 US US12/157,573 patent/US20080255362A1/en not_active Abandoned
- 2008-06-11 US US12/157,574 patent/US20080255352A1/en not_active Abandoned
-
2010
- 2010-03-02 US US12/715,930 patent/US8697865B2/en not_active Expired - Fee Related
-
2011
- 2011-09-15 CY CY20111100894T patent/CY1111850T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008500385A5 (cg-RX-API-DMAC7.html) | ||
| HRP20110640T1 (hr) | Derivati cikličkih amida i njihova proizvodnja te njihova uporaba kao antitromboznih sredstava | |
| JP2010533722A5 (cg-RX-API-DMAC7.html) | ||
| ME01508B (me) | (2S,3R)-N-(2-((3-PIRIDINIL)METIL)-1-AZABICIKLO[2.2.2]OKT-3-IL)BENZOFURAN-2-KARBOKSAMID, NOVI OBLICI SOLl l POSTUPCI ZA NJIHOVU UPOTREBU | |
| PL2625175T3 (pl) | Krystaliczny ((R)-(E)-2-(4-(2-(5-(1-(3,5-dichloropirydyn-4-ylo)etoksy)-1H-indazol-3-ilo)winylo)-1H-pirazol-1-ilo)etanol i jego zastosowanie jako inhibitora FGFR | |
| CY1108428T1 (el) | Μονοϋδροχλωρικο αλας 1-[3 [3-(4-χλωροφαινυλ) προποξυ] προπυλ] - πιπεριδινης | |
| NZ620635A (en) | Compounds for binding to the platelet specific glycoprotein iib/iiia and their use for imaging of thrombi | |
| JP2010507641A5 (cg-RX-API-DMAC7.html) | ||
| ATE502937T1 (de) | Neue polymorphe form von 5-chlor-n-(ä ( 5s )-2- 0x0-3-ä4-( 3-oxo-4-morpholinyl)-phenylü-1,3- oxazolidin-5-ylü -methyl)-2-thiophencarboxamid | |
| JP2010519243A5 (cg-RX-API-DMAC7.html) | ||
| CO6450624A2 (es) | Compuestos vinil indazolilo | |
| PT2305656E (pt) | Isómeros óticos de um metabolito de iloperidona | |
| JP2006519232A5 (cg-RX-API-DMAC7.html) | ||
| MA28476B1 (fr) | 5-6-dialkyl-7-amino-triazolopyrimidines, procede pour fabriquer ces composes et leur utilisation pour lutter contre les champignons et des agents les contenant | |
| PE20090898A1 (es) | Pirrolidina-aril-eteres como antagonistas de receptor de nk3 | |
| JP2004043453A5 (cg-RX-API-DMAC7.html) | ||
| CL2009001310A1 (es) | Compuesto intermediario (2-clorofenil)-[2-(2-hidroxi-2-piridin-4-ilvinil)piridin-3-il]metanona o una sal del mismo en lapreparacion del compuesto {2-[1-(3,5-bistrifluorometilbencil)-5-piridin-4-il-1h-[1,2,3]triazol-4-il]piridin-3-il}-(2-cloofenil)metanona (div. sol. 2680-04). | |
| WO2009010429A3 (en) | Novel heterocyclyl compounds and their use as chemokine antagonists | |
| NO20075022L (no) | (7-(2-(4-(3-trifluormetylfenyl)-1,2,3,6-tetrahydropyrid-1-yl)etyl) isokinolinbesylatsalt, fremstilling og terapeutiske anvendelser derav | |
| IL198775A0 (en) | Novel intermediate and process useful in the preparation of {2-[1-(3,5-bis-trifluoromethyl-benzyl)-5-pyridin-4-yl-1h-[1,2,3]triazol-4-yl]-pyridin-3-yl}-(2-chlorophenyl)-methanone | |
| JP2002507613A5 (cg-RX-API-DMAC7.html) | ||
| JP2007533735A5 (cg-RX-API-DMAC7.html) | ||
| JP2008513510A5 (cg-RX-API-DMAC7.html) | ||
| IL179347A0 (en) | 3-{4-(pyridin-3-yl)phenyl}-5-(1h-1,2,3-triazol-1-ylmethyl)-1,3-oxazolidin-2-ones as antibacterial agents | |
| PL382346A1 (pl) | Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego |