|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
US7662925B2
(en)
|
2002-03-01 |
2010-02-16 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
|
EP1641826A2
(en)
|
2003-06-27 |
2006-04-05 |
Biogen Idec MA Inc. |
Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions
|
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
CA2561264A1
(en)
|
2004-03-24 |
2005-10-06 |
Xencor, Inc. |
Immunoglobulin variants outside the fc region
|
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
|
AU2005304624B2
(en)
|
2004-11-12 |
2010-10-07 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
|
AU2006203889A1
(en)
|
2005-01-05 |
2006-07-13 |
Biogen Idec Ma Inc. |
CRIPTO binding molecules
|
|
WO2006074399A2
(en)
*
|
2005-01-05 |
2006-07-13 |
Biogen Idec Ma Inc. |
Multispecific binding molecules comprising connecting peptides
|
|
CA2606081C
(en)
|
2005-04-26 |
2013-09-17 |
Markus M. Heiss |
Combination of the application of antibodies for immunostimulation together with glucocorticoids
|
|
AU2006239851B2
(en)
*
|
2005-04-26 |
2011-06-16 |
Medimmune, Llc |
Modulation of antibody effector function by hinge domain engineering
|
|
US8309690B2
(en)
|
2005-07-01 |
2012-11-13 |
Medimmune, Llc |
Integrated approach for generating multidomain protein therapeutics
|
|
RS53318B
(sr)
|
2005-07-25 |
2014-10-31 |
Emergent Product Development Seattle, Llc |
Smanjenje broja b-ćelija upotrebom cd37-specifično i cd20-specifično vezujućih molekula
|
|
WO2007041635A2
(en)
|
2005-10-03 |
2007-04-12 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
|
JP4860703B2
(ja)
|
2005-10-06 |
2012-01-25 |
ゼンコー・インコーポレイテッド |
最適化された抗ｃｄ３０抗体
|
|
EP1943332A4
(en)
|
2005-10-14 |
2011-04-13 |
Medimmune Inc |
CELLULAR DISPLAY OF ANTIBODY LIBRARIES
|
|
AR056142A1
(es)
*
|
2005-10-21 |
2007-09-19 |
Amgen Inc |
Metodos para generar el anticuerpo igg monovalente
|
|
EA015992B1
(ru)
|
2006-03-17 |
2012-01-30 |
Байоджен Айдек Эмэй Инк. |
Стабилизированное антитело и многовалентная антигенсвязывающая молекула на его основе, способы получения и использования вышеназванного стабилизированного антитела
|
|
WO2007109321A2
(en)
|
2006-03-20 |
2007-09-27 |
The Regents Of The University Of California |
Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
|
|
US20100278821A1
(en)
|
2006-03-21 |
2010-11-04 |
The Regents Of The University Of California |
N-cadherin: target for cancer diagnosis and therapy
|
|
AU2014200661B2
(en)
*
|
2006-06-12 |
2016-06-30 |
Aptevo Research And Development Llc |
Single-chain multivalent binding proteins with effector function
|
|
NZ573646A
(en)
*
|
2006-06-12 |
2012-04-27 |
Wyeth Llc |
Single-chain multivalent binding proteins with effector function
|
|
EP2383297B8
(en)
|
2006-08-14 |
2023-03-22 |
Xencor, Inc. |
Optimized antibodies that target CD19
|
|
EP2051734B1
(en)
|
2006-08-18 |
2016-10-05 |
Armagen Technologies, Inc. |
Agents for blood-brain barrier delivery
|
|
US8394374B2
(en)
|
2006-09-18 |
2013-03-12 |
Xencor, Inc. |
Optimized antibodies that target HM1.24
|
|
AU2008234248C1
(en)
|
2007-03-29 |
2015-01-22 |
Genmab A/S |
Bispecific antibodies and methods for production thereof
|
|
EP2997976A1
(en)
|
2007-07-27 |
2016-03-23 |
Armagen Technologies, Inc. |
Methods and compositions for increasing alpha-l-iduronidase activity in the cns
|
|
CA2698343C
(en)
|
2007-09-04 |
2018-06-12 |
The Regents Of The University Of California |
High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
|
|
CA2698809C
(en)
*
|
2007-09-14 |
2023-10-17 |
Amgen Inc. |
Homogeneous antibody populations
|
|
ES2667729T3
(es)
|
2007-09-26 |
2018-05-14 |
Ucb Biopharma Sprl |
Fusiones de anticuerpos con doble especificidad
|
|
US20090155255A1
(en)
*
|
2007-09-27 |
2009-06-18 |
Biogen Idec Ma Inc. |
Cd23 binding molecules and methods of use thereof
|
|
EP3714906A1
(en)
*
|
2007-10-03 |
2020-09-30 |
Cornell University |
Treatment of proliferative disorders using radiolabelled antibodies to psma
|
|
WO2011063161A2
(en)
|
2009-11-20 |
2011-05-26 |
The Regents Of The University Of California |
Epithelial membrane protein-2 (emp2) and proliferative vitreoretinopathy (pvr)
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
|
RU2529951C2
(ru)
|
2007-12-26 |
2014-10-10 |
Ксенкор, Инк. |
ВАРИАНТЫ Fc С ИЗМЕНЕННЫМ СВЯЗЫВАНИЕМ C FcRn
|
|
US12492253B1
(en)
|
2008-02-25 |
2025-12-09 |
Xencor, Inc. |
Anti-human C5 antibodies
|
|
JP6013733B2
(ja)
|
2008-04-11 |
2016-10-25 |
エマージェント プロダクト デベロップメント シアトル， エルエルシー |
Ｃｄ３７免疫治療薬および二機能性化学療法薬とのその組合せ
|
|
US20100069616A1
(en)
*
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
|
EP2334705B1
(en)
|
2008-09-26 |
2016-12-14 |
UCB Biopharma SPRL |
Biological products
|
|
US8268314B2
(en)
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
|
WO2010079149A1
(de)
*
|
2009-01-09 |
2010-07-15 |
Ipk Gatersleben |
Fusionsantikörper
|
|
US20120100140A1
(en)
*
|
2009-01-23 |
2012-04-26 |
Biogen Idec Ma Inc. |
Stabilized fc polypeptides with reduced effector function and methods of use
|
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
CA2752510C
(en)
*
|
2009-02-17 |
2024-01-23 |
Neil Bander |
Methods and kits for diagnosis of cancer and prediction of therapeutic value
|
|
WO2010112194A1
(en)
|
2009-04-02 |
2010-10-07 |
F. Hoffmann-La Roche Ag |
Antigen-binding polypeptides and multispecific antibodies comprising them
|
|
KR101431318B1
(ko)
*
|
2009-04-02 |
2014-08-20 |
로슈 글리카트 아게 |
전장 항체 및 단일쇄 ｆａｂ 단편을 포함하는 다중특이성 항체
|
|
SG175078A1
(en)
|
2009-04-07 |
2011-11-28 |
Roche Glycart Ag |
Bispecific anti-erbb-1/anti-c-met antibodies
|
|
ES2537100T3
(es)
|
2009-04-07 |
2015-06-02 |
Roche Glycart Ag |
Anticuerpos biespecíficos trivalentes
|
|
SG175081A1
(en)
|
2009-04-07 |
2011-11-28 |
Roche Glycart Ag |
Bispecific anti-erbb-3/anti-c-met antibodies
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
KR20120108967A
(ko)
|
2009-09-16 |
2012-10-05 |
제넨테크, 인크. |
코일드 코일 및/또는 테더 함유 단백질 복합체 및 그의 용도
|
|
PT2485761T
(pt)
|
2009-10-09 |
2019-05-30 |
Armagen Inc |
Métodos e composições para aumentar a atividade da iduronato 2-sulfatase no snc
|
|
TW201120210A
(en)
|
2009-11-05 |
2011-06-16 |
Hoffmann La Roche |
Glycosylated repeat-motif-molecule conjugates
|
|
EP3135302A1
(en)
|
2009-12-02 |
2017-03-01 |
Imaginab, Inc. |
J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
|
|
US8362210B2
(en)
|
2010-01-19 |
2013-01-29 |
Xencor, Inc. |
Antibody variants with enhanced complement activity
|
|
GB201005064D0
(en)
*
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
|
AR080794A1
(es)
|
2010-03-26 |
2012-05-09 |
Hoffmann La Roche |
Anticuerpos bivalentes biespecificos anti- vegf/ anti-ang-2
|
|
HRP20241208T1
(hr)
|
2010-04-20 |
2024-11-22 |
Genmab A/S |
Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju
|
|
WO2012003493A2
(en)
|
2010-07-01 |
2012-01-05 |
The Regents Of The University Of California |
Protein kinase ck2 gene mutations, amplifications and polymorphisms in human cancers and methods of use
|
|
CA2807278A1
(en)
|
2010-08-24 |
2012-03-01 |
F. Hoffmann - La Roche Ag |
Bispecific antibodies comprising a disulfide stabilized - fv fragment
|
|
CN103328514B
(zh)
|
2010-11-09 |
2015-12-02 |
阿尔蒂单抗治疗公司 |
用于抗原结合的蛋白复合物及其使用方法
|
|
JP5766296B2
(ja)
|
2010-12-23 |
2015-08-19 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
|
|
EP2663647A4
(en)
|
2011-01-14 |
2015-08-19 |
Redwood Bioscience Inc |
POLYPEPTIDE IMMUNOGLOBULINS WITH ALDEHYDIC MARKING AND THEIR USE METHOD
|
|
BR112013019975A2
(pt)
|
2011-02-28 |
2017-08-01 |
Hoffmann La Roche |
proteínas de ligação de antígeno, composição farmacêutica, uso de uma proteína de ligação de antígeno, método para o tratamento de um paciente e método para a preparação de uma proteína de ligação de antígeno, ácido nucleico, vetor e célula hospedeira"
|
|
AR085403A1
(es)
|
2011-02-28 |
2013-09-25 |
Hoffmann La Roche |
Proteinas monovalentes que se unen a antigenos
|
|
CA2830503A1
(en)
|
2011-03-17 |
2012-09-20 |
Minerva Biotechnologies Corporation |
Method for making pluripotent stem cells
|
|
CA2835453A1
(en)
*
|
2011-05-09 |
2012-11-15 |
Minerva Biotechnologies Corporation |
Genetically engineered growth factor variants
|
|
CN104114579B
(zh)
|
2011-10-27 |
2020-01-24 |
健玛保 |
异二聚体蛋白的生成
|
|
JP6486686B2
(ja)
|
2012-02-10 |
2019-03-20 |
ジェネンテック， インコーポレイテッド |
単鎖抗体及び他のヘテロ多量体
|
|
BR112014024903A2
(pt)
|
2012-04-05 |
2017-07-11 |
Hoffmann La Roche |
anticorpos biespecíficos contra tweak humanao e il17 humana e seus usos
|
|
HUE059815T2
(hu)
*
|
2012-05-18 |
2022-12-28 |
Aptevo Res & Development Llc |
Bispecifikus SCFV immunofuziós (BIF) kötõdés a CD123-hoz és a CD3-hoz
|
|
EP2867255B1
(en)
|
2012-06-27 |
2017-07-19 |
F. Hoffmann-La Roche AG |
Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof
|
|
KR20150030744A
(ko)
|
2012-06-27 |
2015-03-20 |
에프. 호프만-라 로슈 아게 |
표적에 특이적으로 결합하는 하나 이상의 결합 단위를 포함하는 항체 Ｆｃ－영역 접합체의 제조 방법 및 그의 용도
|
|
EP2867253B1
(en)
|
2012-06-27 |
2016-09-14 |
F. Hoffmann-La Roche AG |
Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof
|
|
BR112014030843A2
(pt)
|
2012-07-04 |
2019-10-15 |
Hoffmann La Roche |
anticorpo anti-teofilina, formulação farmacêutica e uso do anticorpo
|
|
HUE030858T2
(en)
|
2012-07-04 |
2017-06-28 |
Hoffmann La Roche |
Covalently linked antigen-antibody conjugates
|
|
EP3339328A1
(en)
|
2012-07-04 |
2018-06-27 |
F. Hoffmann-La Roche AG |
Anti-biotin antibodies and methods of use
|
|
JP6273205B2
(ja)
|
2012-10-05 |
2018-01-31 |
協和発酵キリン株式会社 |
ヘテロダイマータンパク質組成物
|
|
TWI635098B
(zh)
|
2013-02-01 |
2018-09-11 |
再生元醫藥公司 |
含嵌合恆定區之抗體
|
|
AU2014254086B2
(en)
|
2013-04-16 |
2018-07-05 |
Genentech, Inc. |
Pertuzumab variants and evaluation thereof
|
|
TWI596107B
(zh)
|
2013-06-25 |
2017-08-21 |
卡地拉保健有限公司 |
單株抗體之新穎純化方法
|
|
CN104341504B
(zh)
|
2013-08-06 |
2017-10-24 |
百奥泰生物科技(广州)有限公司 |
双特异性抗体
|
|
CA2922912A1
(en)
|
2013-10-11 |
2015-04-16 |
F. Hoffmann-La Roche Ag |
Multispecific domain exchanged common variable light chain antibodies
|
|
GB2519786A
(en)
*
|
2013-10-30 |
2015-05-06 |
Sergej Michailovic Kiprijanov |
Multivalent antigen-binding protein molecules
|
|
WO2015079977A1
(ja)
*
|
2013-11-26 |
2015-06-04 |
シャープ株式会社 |
抗体分離方法、抗体評価方法、医薬の評価方法、及び、抗体の２次元電気泳動用キット
|
|
BR112016013562A2
(pt)
|
2013-12-20 |
2017-10-03 |
Hoffmann La Roche |
Anticorpos anti-tau(ps422) humanizados, seus usos, e formulações farmacêuticas
|
|
MX373856B
(es)
|
2014-01-03 |
2020-03-25 |
Hoffmann La Roche |
Conjugados helicoidales-anticuerpo anti-helicoidal unidos covalentemente y usos de los mismos.
|
|
JP6521464B2
(ja)
|
2014-01-03 |
2019-05-29 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
共有結合で連結されたポリペプチド毒素−抗体コンジュゲート
|
|
JP6476194B2
(ja)
|
2014-01-03 |
2019-02-27 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
二重特異性抗ハプテン／抗血液脳関門受容体抗体、それらの複合体、及び血液脳関門シャトルとしてのそれらの使用
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
WO2015138920A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
EP3593812A3
(en)
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
|
TWI754319B
(zh)
|
2014-03-19 |
2022-02-01 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
|
DK3160513T3
(da)
|
2014-06-30 |
2020-04-06 |
Glykos Finland Oy |
Saccharidderivat af en toksisk payload og antistofkonjugater deraf
|
|
CA2895659A1
(en)
|
2014-07-01 |
2016-01-01 |
Pfizer Inc. |
Bispecific heterodimeric diabodies and uses thereof
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
AU2015292744C1
(en)
|
2014-07-21 |
2021-01-21 |
Novartis Ag |
Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
|
|
US9777061B2
(en)
|
2014-07-21 |
2017-10-03 |
Novartis Ag |
Treatment of cancer using a CD33 chimeric antigen receptor
|
|
EP4205749A1
(en)
|
2014-07-31 |
2023-07-05 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing cells
|
|
JP6919118B2
(ja)
|
2014-08-14 |
2021-08-18 |
ノバルティス アーゲー |
ＧＦＲα−４キメラ抗原受容体を用いる癌の治療
|
|
EP3183268B1
(en)
|
2014-08-19 |
2020-02-12 |
Novartis AG |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
|
KR20250067191A
(ko)
|
2014-09-17 |
2025-05-14 |
노파르티스 아게 |
입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
|
|
TW201628649A
(zh)
|
2014-10-09 |
2016-08-16 |
再生元醫藥公司 |
減少醫藥調配物中微可見顆粒之方法
|
|
CN114920840A
(zh)
|
2014-10-14 |
2022-08-19 |
诺华股份有限公司 |
针对pd-l1的抗体分子及其用途
|
|
RS60739B1
(sr)
|
2014-11-17 |
2020-09-30 |
Regeneron Pharma |
Postupci za lečenje tumora upotrebom cd3xcd20 bispecifičnog antitela
|
|
WO2016087416A1
(en)
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
|
WO2016097300A1
(en)
|
2014-12-19 |
2016-06-23 |
Genmab A/S |
Rodent bispecific heterodimeric proteins
|
|
US10538589B2
(en)
*
|
2015-01-14 |
2020-01-21 |
Armagen Inc. |
Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU
|
|
CA2972151C
(en)
|
2015-02-05 |
2022-10-11 |
Molecular Templates, Inc. |
Multivalent cd20-binding molecules comprising shiga toxin a subunit effector regions and enriched compositions thereof
|
|
PL3277725T3
(pl)
|
2015-03-30 |
2021-06-14 |
Regeneron Pharmaceuticals, Inc. |
Regiony stałe łańcucha ciężkiego o zmniejszonym wiązaniu do receptorów Fc gamma
|
|
US10253086B2
(en)
|
2015-04-08 |
2019-04-09 |
Novartis Ag |
CD20 therapies, CD22 therapies, and combination therapies with a CD19 chimeric antigen receptor (CAR)-expressing cell
|
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
EP3744732B1
(en)
|
2015-06-24 |
2025-09-10 |
F. Hoffmann-La Roche AG |
Humanized anti-tau(ps422) antibodies and methods of use
|
|
US20180179274A1
(en)
|
2015-06-26 |
2018-06-28 |
Institute For Research In Biomedicine |
Proteins comprising a mutated lair-1 fragment and uses thereof
|
|
PL3317301T3
(pl)
|
2015-07-29 |
2021-11-15 |
Novartis Ag |
Terapie skojarzone zawierające cząsteczki przeciwciał przeciw lag-3
|
|
CN114272371A
(zh)
|
2015-07-29 |
2022-04-05 |
诺华股份有限公司 |
包含抗pd-1抗体分子的联合疗法
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
EP3331564B1
(en)
|
2015-08-07 |
2025-01-08 |
Imaginab, Inc. |
Antigen binding constructs to target molecules
|
|
UA126278C2
(uk)
|
2015-09-21 |
2022-09-14 |
Аптево Рісьорч Енд Девелопмент Ллс |
Поліпептиди, які зв'язують cd3
|
|
KR20180056770A
(ko)
|
2015-10-06 |
2018-05-29 |
시티 오브 호프 |
Psca로 표적화된 키메라 항원 수용체
|
|
WO2017059878A1
(en)
|
2015-10-07 |
2017-04-13 |
Humabs Biomed Sa |
Antibodies that potently neutralize hepatitis b virus and uses thereof
|
|
ES2894304T3
(es)
|
2015-10-25 |
2022-02-14 |
Sanofi Sa |
Proteínas de unión triespecíficas y/o trivalentes para la prevención o tratamiento de infección por VIH
|
|
KR102833068B1
(ko)
|
2015-12-17 |
2025-07-14 |
노파르티스 아게 |
Pd-1에 대한 항체 분자 및 그의 용도
|
|
RU2018125603A
(ru)
|
2015-12-17 |
2020-01-21 |
Новартис Аг |
Комбинация ингибитора с-мет с молекулой антитела к pd-1 и ее применения
|
|
JP7082055B2
(ja)
|
2015-12-22 |
2022-06-07 |
ノバルティス アーゲー |
抗癌治療における組み合わせ使用のためのメソテリンキメラ抗原受容体（ｃａｒ）およびｐｄ－ｌ１阻害剤に対する抗体
|
|
EP3851457A1
(en)
|
2016-01-21 |
2021-07-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
|
US20200281973A1
(en)
|
2016-03-04 |
2020-09-10 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
PL3443006T3
(pl)
|
2016-04-13 |
2024-01-29 |
Sanofi |
Trójswoiste i/lub triwalentne białka wiążące
|
|
EP3443006B1
(en)
|
2016-04-13 |
2023-08-02 |
Sanofi |
Trispecific and/or trivalent binding proteins
|
|
DK3443096T5
(da)
|
2016-04-15 |
2024-09-09 |
Novartis Ag |
Sammensætninger og fremgangsmåder til selektiv ekspression af kimære antigenreceptorer
|
|
US11208632B2
(en)
|
2016-04-26 |
2021-12-28 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
|
WO2017210617A2
(en)
|
2016-06-02 |
2017-12-07 |
Porter, David, L. |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
KR20230136699A
(ko)
|
2016-06-06 |
2023-09-26 |
노쓰웨스턴유니버시티 |
융합 단백질 작제물
|
|
WO2018010789A1
(en)
|
2016-07-13 |
2018-01-18 |
Humabs Biomed Sa |
Novel antibodies specifically binding to zika virus epitopes and uses thereof
|
|
SG11201900344YA
(en)
|
2016-07-15 |
2019-02-27 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
EP3491016A1
(en)
|
2016-07-28 |
2019-06-05 |
Novartis AG |
Combination therapies of chimeric antigen receptors and pd-1 inhibitors
|
|
CA3032581A1
(en)
|
2016-08-01 |
2018-02-08 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
|
US11020686B2
(en)
|
2016-08-16 |
2021-06-01 |
Regeneron Pharmaceuticals, Inc. |
Methods for quantitating individual antibodies from a mixture
|
|
KR102559732B1
(ko)
|
2016-09-21 |
2023-07-26 |
압테보 리서치 앤드 디벨롭먼트 엘엘씨 |
Cd123 결합 단백질 그리고 관련된 조성물 및 방법
|
|
CN117866991A
(zh)
|
2016-10-07 |
2024-04-12 |
诺华股份有限公司 |
用于治疗癌症的嵌合抗原受体
|
|
JP7102401B2
(ja)
|
2016-10-25 |
2022-07-19 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
クロマトグラフィーデータ解析のための方法およびシステム
|
|
ES2971981T3
(es)
|
2017-01-25 |
2024-06-10 |
Molecular Templates Inc |
Moléculas de reconocimiento de células que comprenden efectores de la subunidad A de la toxina Shiga desinmunizados y epítopos de células T CD8+
|
|
EP3574005B1
(en)
|
2017-01-26 |
2021-12-15 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
US11266745B2
(en)
|
2017-02-08 |
2022-03-08 |
Imaginab, Inc. |
Extension sequences for diabodies
|
|
WO2018160731A1
(en)
|
2017-02-28 |
2018-09-07 |
Novartis Ag |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
US12383609B2
(en)
|
2017-04-19 |
2025-08-12 |
Institute For Research In Biomedicine |
Plasmodium sporozoite NPDP peptides as vaccine and target novel malaria vaccines and antibodies binding to
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
WO2018201056A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
CU24606B1
(es)
|
2017-06-22 |
2022-06-06 |
Novartis Ag |
Moléculas de anticuerpo que se unen a cd73
|
|
CA3066747A1
(en)
|
2017-06-27 |
2019-01-03 |
Novartis Ag |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
|
SG10201913147WA
(en)
|
2017-07-11 |
2020-02-27 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
|
IL319798A
(en)
|
2017-07-20 |
2025-05-01 |
Novartis Ag |
ANTI-LAG-3 Antibody Dosage Regimens and Their Uses
|
|
WO2019024979A1
(en)
|
2017-07-31 |
2019-02-07 |
Institute For Research In Biomedicine |
FUNCTIONAL DOMAIN ANTIBODIES IN THE ELBOW REGION
|
|
WO2019042555A1
(en)
|
2017-08-31 |
2019-03-07 |
Humabs Biomed Sa |
MULTISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO ZIKA VIRUS EPITOPES AND USES THEREOF
|
|
KR102798879B1
(ko)
|
2017-09-19 |
2025-04-30 |
리제너론 파아마슈티컬스, 인크. |
입자 형성을 감소시키는 방법 및 그것에 의해 형성된 조성물
|
|
MA50359A
(fr)
|
2017-10-10 |
2020-08-19 |
Sanofi Sa |
Anticorps anti-cd38 et procédés d'utilisation
|
|
KR20200067197A
(ko)
|
2017-10-20 |
2020-06-11 |
에프. 호프만-라 로슈 아게 |
단일특이적 항체로부터 다중특이적 항체의 생성 방법
|
|
AU2018358883B2
(en)
|
2017-10-30 |
2025-09-25 |
F. Hoffmann-La Roche Ag |
Method for in vivo generation of multispecific antibodies from monospecific antibodies
|
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
|
CA3081602A1
(en)
|
2017-11-16 |
2019-05-23 |
Novartis Ag |
Combination therapies
|
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
CA3090249A1
(en)
|
2018-01-31 |
2019-08-08 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
EP3781673A1
(en)
|
2018-04-18 |
2021-02-24 |
Ucl Business Ltd |
Method for enhancing the suppressive properties of treg cells
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
AU2019272575A1
(en)
|
2018-05-21 |
2020-12-10 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by NK cells
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
US11608382B2
(en)
|
2018-06-13 |
2023-03-21 |
Novartis Ag |
BCMA chimeric antigen receptors and uses thereof
|
|
WO2019246293A2
(en)
|
2018-06-19 |
2019-12-26 |
Atarga, Llc |
Antibody molecules to complement component 5 and uses thereof
|
|
TW202448568A
(zh)
|
2018-07-02 |
2024-12-16 |
美商里珍納龍藥品有限公司 |
自混合物製備多肽之系統及方法
|
|
CN112955465A
(zh)
|
2018-07-03 |
2021-06-11 |
马伦戈治疗公司 |
抗tcr抗体分子及其用途
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
US12281152B2
(en)
|
2018-08-01 |
2025-04-22 |
City Of Hope |
TAG72 targeted chimeric antigen receptor modified T cells for treatment of TAG72-positive tumors
|
|
MX2021002190A
(es)
|
2018-08-31 |
2021-05-14 |
Regeneron Pharma |
Estrategia de dosificacion que mitiga el sindrome de liberacion de citoquinas para los anticuerpos biespecificos cd3/cd20.
|
|
CA3115679A1
(en)
|
2018-10-09 |
2020-04-16 |
Sanofi |
Trispecific anti-cd38, anti-cd28, and anti-cd3 binding proteins and methods of use for treating viral infection
|
|
WO2020078568A1
(en)
|
2018-10-19 |
2020-04-23 |
Humabs Biomed Sa |
Antibodies and methods for treatment of lyssavirus infection
|
|
KR20210107628A
(ko)
|
2018-11-13 |
2021-09-01 |
콤파스 테라퓨틱스 엘엘씨 |
체크포인트 분자에 대한 다중특이적 결합 작제물 및 이의 용도
|
|
TWI874341B
(zh)
|
2018-12-18 |
2025-03-01 |
美商健生生物科技公司 |
產生異二聚體抗體之方法
|
|
DK3898668T5
(da)
|
2018-12-19 |
2024-08-05 |
Humabs Biomed Sa |
Antistoffer der neutraliserer hepatitis b virus og anvendelser deraf
|
|
EP3897672B1
(en)
|
2018-12-20 |
2023-08-09 |
VIR Biotechnology, Inc. |
Combination hbv therapy
|
|
KR20210106491A
(ko)
|
2018-12-20 |
2021-08-30 |
노파르티스 아게 |
약제학적 조합물
|
|
EP3897637A1
(en)
|
2018-12-20 |
2021-10-27 |
Novartis AG |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
BR112021015676A2
(pt)
*
|
2019-02-15 |
2021-10-05 |
University Of Southern California |
Composições de anticorpo lym-1 e lym-2 e construções car aprimoradas
|
|
CA3123519A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
EP3924054B1
(en)
|
2019-02-15 |
2025-04-02 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
SG11202109061YA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Multifunctional molecules that bind to t cell related cancer cells and uses thereof
|
|
CA3130508A1
(en)
|
2019-02-21 |
2020-08-27 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to nkp30 and uses thereof
|
|
WO2020172553A1
(en)
|
2019-02-22 |
2020-08-27 |
Novartis Ag |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
PH12021552414A1
(en)
|
2019-03-29 |
2022-07-25 |
Atarga Llc |
Anti fgf23 antibody
|
|
US11613576B2
(en)
|
2019-04-09 |
2023-03-28 |
Sanofi |
Trispecific binding proteins, methods, and uses thereof
|
|
WO2020221451A1
(en)
|
2019-04-30 |
2020-11-05 |
Humabs Biomed Sa |
Antibodies binding to plasmodium circumsporozoite protein and uses thereof
|
|
EA202290040A1
(ru)
*
|
2019-06-13 |
2022-03-05 |
Ридженерон Фармасьютикалз, Инк. |
Способы удаления нежелательных компонентов в многостадийных хроматографических процессах
|
|
EP3757127A1
(en)
|
2019-06-28 |
2020-12-30 |
Institute for Research in Biomedicine |
Deimmunized antibodies binding to alpha-4 integrin and uses thereof
|
|
MX2022002231A
(es)
|
2019-08-29 |
2022-03-22 |
Vir Biotechnology Inc |
Composiciones de anticuerpos y metodos para tratar la infeccion por el virus de la hepatitis b.
|
|
CA3158298A1
(en)
|
2019-10-21 |
2021-04-29 |
Novartis Ag |
Combination therapies with venetoclax and tim-3 inhibitors
|
|
CA3157665A1
(en)
|
2019-10-21 |
2021-04-29 |
Novartis Ag |
Tim-3 inhibitors and uses thereof
|
|
CN113416258B
(zh)
|
2019-10-24 |
2023-08-29 |
北京免疫方舟医药科技有限公司 |
一种多特异性抗体及其制备方法和用途
|
|
US20210155671A1
(en)
|
2019-11-24 |
2021-05-27 |
Molecular Templates, Inc. |
Uses of cd20-binding molecules and additional therapeutic agents
|
|
JP7714545B2
(ja)
|
2019-11-26 |
2025-07-29 |
ノバルティス アーゲー |
キメラ抗原受容体及びその使用
|
|
BR112022011998A2
(pt)
|
2019-12-20 |
2022-08-30 |
Novartis Ag |
Usos de anticorpos anti-tgfss e inibidores de checkpoint para o tratamento de doenças proliferativas
|
|
AU2020416273A1
(en)
|
2020-01-03 |
2022-07-28 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
JP2023510393A
(ja)
|
2020-01-17 |
2023-03-13 |
ノバルティス アーゲー |
骨髄異形成症候群または慢性骨髄単球性白血病の処置に使用するためのｔｉｍ－３阻害剤と低メチル化剤とを含む組合せ
|
|
EP4090762A1
(en)
|
2020-01-17 |
2022-11-23 |
Becton, Dickinson and Company |
Methods and compositions for single cell secretomics
|
|
KR20220147109A
(ko)
|
2020-02-27 |
2022-11-02 |
노파르티스 아게 |
키메라 항원 수용체 발현 세포의 제조 방법
|
|
GB202007842D0
(en)
|
2020-05-26 |
2020-07-08 |
Quell Therapeutics Ltd |
Polypeptide useful in adoptive cell therapy
|
|
EP4168007A1
(en)
|
2020-06-23 |
2023-04-26 |
Novartis AG |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
JP2023531520A
(ja)
|
2020-06-24 |
2023-07-24 |
ヴィア・バイオテクノロジー・インコーポレイテッド |
操作されたｂ型肝炎ウイルス中和抗体およびその使用
|
|
EP4182025A1
(en)
|
2020-07-16 |
2023-05-24 |
Novartis AG |
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
GB202013477D0
(en)
|
2020-08-27 |
2020-10-14 |
Quell Therapeutics Ltd |
Nucleic acid constructs for expressing polypeptides in cells
|
|
US20230338587A1
(en)
|
2020-08-31 |
2023-10-26 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
WO2022043557A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
EP4240765A2
(en)
|
2020-11-06 |
2023-09-13 |
Novartis AG |
Antibody fc variants
|
|
IL302700A
(en)
|
2020-11-13 |
2023-07-01 |
Novartis Ag |
Combination therapies with chimeric antigen receptor (car)-expressing cells
|
|
JP2023552846A
(ja)
|
2020-12-08 |
2023-12-19 |
フマブス バイオメッド エスアー |
メタニューモウイルスのｆ－タンパク質に結合する抗体およびその使用
|
|
EP4284428A1
(en)
|
2021-01-26 |
2023-12-06 |
VIR Biotechnology, Inc. |
Compositions and methods for treating hepatitis b virus infection
|
|
EP4284510A1
(en)
|
2021-01-29 |
2023-12-06 |
Novartis AG |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
US20250129142A1
(en)
|
2021-09-07 |
2025-04-24 |
Institute For Research In Biomedicine |
Antibodies binding to tetanus toxin and uses thereof
|
|
US20250223376A1
(en)
|
2021-09-20 |
2025-07-10 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
US20250034559A1
(en)
|
2021-11-17 |
2025-01-30 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
US20230383010A1
(en)
|
2022-02-07 |
2023-11-30 |
Visterra, Inc. |
Anti-idiotype antibody molecules and uses thereof
|
|
EP4522757A2
(en)
|
2022-05-13 |
2025-03-19 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
CA3263767A1
(en)
|
2022-08-03 |
2024-02-08 |
Voyager Therapeutics, Inc. |
COMPOSITIONS AND PROCESSES ALLOWING CROSSING THE BLOOD-BRAIN BARRIER
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
WO2025129010A1
(en)
|
2023-12-14 |
2025-06-19 |
Genentech, Inc. |
Methods of structure determination using antibodies
|