JP2006526649A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006526649A5 JP2006526649A5 JP2006515040A JP2006515040A JP2006526649A5 JP 2006526649 A5 JP2006526649 A5 JP 2006526649A5 JP 2006515040 A JP2006515040 A JP 2006515040A JP 2006515040 A JP2006515040 A JP 2006515040A JP 2006526649 A5 JP2006526649 A5 JP 2006526649A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- immunogenic composition
- composition according
- additional
- polysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47501003P | 2003-06-02 | 2003-06-02 | |
| US60/475,010 | 2003-06-02 | ||
| US51307403P | 2003-10-21 | 2003-10-21 | |
| US60/513,074 | 2003-10-21 | ||
| PCT/US2004/017125 WO2005020964A1 (en) | 2003-06-02 | 2004-06-02 | Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012014940A Division JP2012082228A (ja) | 2003-06-02 | 2012-01-27 | 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006526649A JP2006526649A (ja) | 2006-11-24 |
| JP2006526649A5 true JP2006526649A5 (enExample) | 2007-07-19 |
| JP5557415B2 JP5557415B2 (ja) | 2014-07-23 |
Family
ID=34278342
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006515040A Expired - Lifetime JP5557415B2 (ja) | 2003-06-02 | 2004-06-02 | 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物 |
| JP2012014940A Withdrawn JP2012082228A (ja) | 2003-06-02 | 2012-01-27 | 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物 |
| JP2014056365A Withdrawn JP2014111671A (ja) | 2003-06-02 | 2014-03-19 | 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012014940A Withdrawn JP2012082228A (ja) | 2003-06-02 | 2012-01-27 | 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物 |
| JP2014056365A Withdrawn JP2014111671A (ja) | 2003-06-02 | 2014-03-19 | 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9107831B2 (enExample) |
| EP (2) | EP1631264B8 (enExample) |
| JP (3) | JP5557415B2 (enExample) |
| CN (1) | CN1798548B (enExample) |
| AT (1) | ATE437633T2 (enExample) |
| CA (1) | CA2528007C (enExample) |
| CY (1) | CY1109492T1 (enExample) |
| DE (1) | DE602004022286D1 (enExample) |
| ES (2) | ES2596553T3 (enExample) |
| PL (1) | PL1631264T5 (enExample) |
| PT (1) | PT1631264E (enExample) |
| WO (1) | WO2005020964A1 (enExample) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| WO2003080149A2 (en) | 2002-03-20 | 2003-10-02 | Mannkind Corporation | Inhalation apparatus |
| AU2003299994A1 (en) | 2002-12-27 | 2004-07-29 | Chiron Corporation | Immunogenic compositions containing phospholpid |
| US20070148188A1 (en) * | 2003-07-30 | 2007-06-28 | Merck & Co., Inc. | Anthrax vaccine |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| HUE025151T2 (en) | 2004-08-23 | 2016-01-28 | Mannkind Corp | Diceto-piperazine salts for drug delivery |
| ES2434029T3 (es) * | 2004-11-15 | 2013-12-13 | Novartis Vaccines And Diagnostics, Inc. | Composiciones inmunogénicas que contiene antígeno de antrax, micropartículas de polímero biodegradable, y adyuvante inmunológico que contiene polinucleótido |
| GB0505518D0 (en) * | 2005-03-17 | 2005-04-27 | Chiron Srl | Combination vaccines with whole cell pertussis antigen |
| US9486515B2 (en) | 2005-06-27 | 2016-11-08 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
| KR101486397B1 (ko) * | 2005-09-14 | 2015-01-28 | 맨카인드 코포레이션 | 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법 |
| US9999591B2 (en) | 2005-09-21 | 2018-06-19 | The United States Of America As Represented By The Secretary Of The Navy | Immunogenic composition against Campylobacter jejuni |
| KR20080096809A (ko) | 2006-02-22 | 2008-11-03 | 맨카인드 코포레이션 | 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법 |
| GB0605247D0 (en) * | 2006-03-15 | 2006-04-26 | Chiron Srl | Compositions and methods for immunisation |
| WO2007109813A1 (en) * | 2006-03-23 | 2007-09-27 | Novartis Ag | Imidazoquinoxaline compounds as immunomodulators |
| KR20150042304A (ko) * | 2006-04-14 | 2015-04-20 | 맨카인드 코포레이션 | 글루카곤 유사 펩타이드 1 (glp-1) 약제학적 제제 |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| EP2185189B1 (en) * | 2007-07-27 | 2017-09-27 | The United States Of America As Represented By The Secretary Of The Navy | Capsule composition for use as immunogen against campylobacter jejuni |
| EP2244695A1 (en) * | 2007-12-07 | 2010-11-03 | Novartis AG | Compositions for inducing immune responses |
| KR101695800B1 (ko) | 2008-03-05 | 2017-02-22 | 사노피 파스퇴르 | 항원보강제 함유 백신 조성물의 안정화 방법 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2929343T3 (es) | 2008-06-13 | 2022-11-28 | Mannkind Corp | Inhalador de polvo seco accionado por aspiración para la administración de fármacos |
| MX2010014240A (es) | 2008-06-20 | 2011-03-25 | Mankind Corp | Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion. |
| TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| WO2010105094A1 (en) | 2009-03-11 | 2010-09-16 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| MY157166A (en) | 2009-06-12 | 2016-05-13 | Mankind Corp | Diketopiperazine microparticles with defined specific surface areas |
| CN106421743A (zh) * | 2009-07-29 | 2017-02-22 | 贝恩德·赫尔穆特·阿达姆·雷姆 | 聚合物微粒及其用途 |
| WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| WO2011150258A1 (en) * | 2010-05-26 | 2011-12-01 | Selecta Biosciences, Inc. | Dose selection of adjuvanted synthetic nanocarriers |
| BR112012033060A2 (pt) | 2010-06-21 | 2018-02-27 | Mannkind Corp | métodos de sistema de liberação de fármaco em pó seco |
| PL3831406T3 (pl) | 2010-08-23 | 2024-09-09 | Wyeth Llc | Stabilne preparaty antygenów rLP2086 Neisseria meningitidis |
| RU2546873C2 (ru) | 2010-09-10 | 2015-04-10 | УАЙТ ЭлЭлСи | Нелипидизированные варианты антигенов neisseria meningitidis orf2086 |
| AU2012236150B2 (en) | 2011-04-01 | 2016-03-31 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| JP6100762B2 (ja) | 2011-06-02 | 2017-03-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 膜で被包されたナノ粒子および使用方法 |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
| WO2013082503A1 (en) * | 2011-12-01 | 2013-06-06 | Flow Pharma, Inc. | Peptide particle formulation |
| MY167723A (en) | 2012-03-09 | 2018-09-21 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| EP2852414B9 (en) * | 2012-05-22 | 2020-12-09 | GlaxoSmithKline Biologicals SA | Meningococcus serogroup x conjugate |
| AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| US9802987B2 (en) | 2013-03-08 | 2017-10-31 | Pfizer Inc. | Immunogenic fusion polypeptides |
| KR102246914B1 (ko) | 2013-03-15 | 2021-04-30 | 맨카인드 코포레이션 | 미세결정성 디케토피페라진 조성물 및 방법 |
| CN114848614A (zh) | 2013-07-18 | 2022-08-05 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| WO2015021390A2 (en) | 2013-08-08 | 2015-02-12 | The Regents Of The University Of California | Nanoparticles leverage biological membranes to target pathogens for disease treatment and diagnosis |
| EP4098276A1 (en) | 2013-09-08 | 2022-12-07 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| US20170000875A1 (en) * | 2013-12-02 | 2017-01-05 | Arytha Biosciences, Llc | Toxoid preparation and uses thereof |
| CN106163504B (zh) | 2014-03-20 | 2021-02-09 | 加利福尼亚大学董事会 | 水凝胶毒素-吸收或结合纳米颗粒 |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US20150359880A1 (en) * | 2014-06-16 | 2015-12-17 | Biomune Company | Dual adjuvant vaccine compositions, preparation and uses |
| JP6530051B2 (ja) * | 2014-08-07 | 2019-06-12 | ザ ユナイテッド ステイツ オブ アメリカ アズ レプレゼンティッド バイ ザ セクレタリー オブ ザ ネイビーThe United States Of America As Represented By The Secretary Of The Navy | カンピロバクター ジェジュニに対する免疫原性組成物 |
| CN104225588B (zh) * | 2014-08-20 | 2016-06-22 | 北京智飞绿竹生物制药有限公司 | b型流感嗜血杆菌结合疫苗的制备方法 |
| EP4183408A1 (en) * | 2014-09-24 | 2023-05-24 | The United States of America as Represented by The Secretary of the Navy | Combined enterotoxigenic escherichia coli and shigella recombinant |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| AU2015342943B2 (en) * | 2014-11-05 | 2018-06-28 | The United States Of America As Represented By The Secretary Of The Navy | Synthetic antigen constructs against Campylobacter jejuni |
| US10500261B2 (en) | 2014-11-05 | 2019-12-10 | The United States Of America As Represented By The Secretary Of The Navy | Synthetic antigen constructs against campylobacter jejuni |
| US10888611B2 (en) | 2015-02-19 | 2021-01-12 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| US10610493B2 (en) | 2015-04-29 | 2020-04-07 | The Regents Of The University Of California | Detoxification using nanoparticles |
| WO2018013865A1 (en) * | 2016-07-13 | 2018-01-18 | uBiome, Inc. | Method and system for microbial pharmacogenomics |
| PE20191107A1 (es) | 2017-01-31 | 2019-08-26 | Pfizer | Composiciones de neisseria meningitidis y metodos respectivos |
| US12318437B2 (en) | 2018-07-21 | 2025-06-03 | Biological E Limited | Vaccine formulations comprising preservative |
| WO2021059181A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| CN114748616A (zh) * | 2022-05-23 | 2022-07-15 | 中国医学科学院医学生物学研究所 | 一种成人青少年用无细胞百白破联合疫苗及其制备方法 |
Family Cites Families (101)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1565298A (en) | 1925-12-15 | Stop check announcing device for adding machines | ||
| US715902A (en) | 1902-03-10 | 1902-12-16 | John Thomson Press Company | Changer. |
| US2800457A (en) | 1953-06-30 | 1957-07-23 | Ncr Co | Oil-containing microscopic capsules and method of making them |
| NL134977C (enExample) | 1962-07-11 | |||
| US5324513A (en) | 1984-03-07 | 1994-06-28 | Institut Pasteur | Composition useful for the fabrication of vaccines |
| US6309669B1 (en) * | 1984-03-16 | 2001-10-30 | The United States Of America As Represented By The Secretary Of The Army | Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix |
| US5098704A (en) | 1984-06-18 | 1992-03-24 | Chiron Corporation | Hepatitis surface antigen particle vaccine |
| US4722840A (en) | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| JP2661044B2 (ja) | 1986-06-17 | 1997-10-08 | カイロン コーポレイション | 肝炎δの診断薬およびワクチン |
| GB8815795D0 (en) | 1988-07-02 | 1988-08-10 | Bkl Extrusions Ltd | Glazing bead |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| EP0378881B1 (en) | 1989-01-17 | 1993-06-09 | ENIRICERCHE S.p.A. | Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines |
| JPH0832638B2 (ja) | 1989-05-25 | 1996-03-29 | カイロン コーポレイション | サブミクロン油滴乳剤を含んで成るアジュバント製剤 |
| US4944331A (en) | 1989-06-22 | 1990-07-31 | Allied-Signal Inc. | Solenoid valve |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| DE69113564T2 (de) | 1990-08-13 | 1996-05-30 | American Cyanamid Co | Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff. |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| IL101715A (en) | 1991-05-02 | 2005-06-19 | Amgen Inc | Recombinant dna-derived cholera toxin subunit analogs |
| IT1253009B (it) | 1991-12-31 | 1995-07-10 | Sclavo Ricerca S R L | Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini |
| AU3630093A (en) | 1992-03-02 | 1993-10-05 | Biocine S.P.A. | Helicobacter pylori proteins useful for vaccines and diagnostics |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| NZ253137A (en) | 1992-06-25 | 1996-08-27 | Smithkline Beecham Biolog | Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a. |
| FR2695563B1 (fr) | 1992-09-11 | 1994-12-02 | Pasteur Institut | Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires. |
| JPH08505625A (ja) | 1993-01-11 | 1996-06-18 | ダナ−ファーバー キャンサー インスティチュート | 細胞毒性tリンパ球応答の誘導 |
| US5981719A (en) | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| EP0689454B2 (en) | 1993-03-23 | 2005-02-23 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccine compositions containing 3-o deacylated monophosphoryl lipid a |
| GB9311454D0 (en) | 1993-06-03 | 1993-07-21 | Agricultural & Food Res | Pharmaceutical compositions |
| US5728385A (en) | 1993-08-12 | 1998-03-17 | Classen Immunotherapies, Inc. | Method and composition for an early vaccine to protect against both common infectious diseases and chronic immune mediated disorders or their sequelae |
| US6015686A (en) | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US5902565A (en) * | 1993-12-24 | 1999-05-11 | Csl Limited | Spray dried vaccine preparation comprising aluminium adsorbed immunogens |
| GB9412273D0 (en) | 1994-06-18 | 1994-08-10 | Univ Nottingham | Administration means |
| DE69535905D1 (de) | 1994-07-15 | 2009-02-26 | Coley Pharm Group Inc | Immunomodulatorische Oligonukleotide |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6007845A (en) * | 1994-07-22 | 1999-12-28 | Massachusetts Institute Of Technology | Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers |
| CA2207961A1 (en) | 1995-01-05 | 1996-07-11 | Robert J. Levy | Surface-modified nanoparticles and method of making and using same |
| IL117483A (en) | 1995-03-17 | 2008-03-20 | Bernard Brodeur | MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K. |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| GB9514285D0 (en) | 1995-07-13 | 1995-09-13 | Univ Nottingham | Polymeric lamellar substrate particles for drug delivery |
| JP2002515734A (ja) | 1996-01-02 | 2002-05-28 | カイロン コーポレイション | 遺伝子改変された樹状細胞により媒介される免疫刺激 |
| EP1997900A3 (en) | 1996-04-05 | 2010-10-06 | Novartis Vaccines and Diagnostics, Inc. | Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis |
| US6451592B1 (en) | 1996-04-05 | 2002-09-17 | Chiron Corporation | Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis |
| GB9619002D0 (en) | 1996-09-11 | 1996-10-23 | Oxford Biosciences Ltd | Particle delivery |
| US5759003A (en) | 1996-07-22 | 1998-06-02 | Greenway; John Michael | Combined screw and clearance drill |
| DE19630390A1 (de) | 1996-07-26 | 1998-01-29 | Chiron Behring Gmbh & Co | Proteine, insbesondere Membranproteine von Helicobacter pylori, ihre Herstellung und Verwendung |
| EP0930893B1 (en) | 1996-10-11 | 2005-04-13 | The Regents of The University of California | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates |
| US20060002949A1 (en) * | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
| US5783567A (en) | 1997-01-22 | 1998-07-21 | Pangaea Pharmaceuticals, Inc. | Microparticles for delivery of nucleic acid |
| US6884435B1 (en) * | 1997-01-30 | 2005-04-26 | Chiron Corporation | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| AU747577B2 (en) | 1997-01-30 | 2002-05-16 | Novartis Vaccines And Diagnostics, Inc. | Use of microparticles with adsorbed antigen to stimulate immune responses |
| AU753688B2 (en) | 1997-03-10 | 2002-10-24 | Ottawa Civic Loeb Research Institute | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| US6355257B1 (en) | 1997-05-08 | 2002-03-12 | Corixa Corporation | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| WO1998052581A1 (en) | 1997-05-20 | 1998-11-26 | Ottawa Civic Hospital Loeb Research Institute | Vectors and methods for immunization or therapeutic protocols |
| JP4101888B2 (ja) | 1997-06-06 | 2008-06-18 | ダイナバックス テクノロジーズ コーポレイション | 免疫刺激オリゴヌクレオチド、その組成物およびその使用方法 |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| CA2302554C (en) | 1997-09-05 | 2007-04-10 | Smithkline Beecham Biologicals S.A. | Oil in water emulsions containing saponins |
| EP1029052B1 (en) | 1997-11-06 | 2010-08-04 | Novartis Vaccines and Diagnostics S.r.l. | Neisserial antigens |
| US20040258703A1 (en) * | 1997-11-14 | 2004-12-23 | The Government Of The Us, As Represented By The Secretary Of The Army | Skin-active adjuvants for transcutaneous immunization |
| ES2278420T3 (es) | 1997-11-21 | 2007-08-01 | Serono Genetics Institute S.A. | Secuencia genomica y polipeptidos de chlamydia pneumoniae, fragmentos de los mismos y uso de los mismos, en particular para diagnostico, prevencion y tratamiento de infeccion. |
| CN1280619A (zh) | 1997-11-28 | 2001-01-17 | 根瑟特公司 | 沙眼衣原体的基因组序列和多肽,其片段以及其用途,特别是用于诊断、预防和治疗感染 |
| CA2314934C (en) | 1997-12-16 | 2006-08-29 | Chiron Corporation | Use of microparticles combined with submicron oil-in-water emulsions |
| AU1979599A (en) | 1998-01-14 | 1999-08-02 | Chiron S.P.A. | (neisseria meningitidis) antigens |
| US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
| US6207171B1 (en) * | 1998-03-27 | 2001-03-27 | Avant Immunotherapeutics, Inc. | Polyphosphazene microspheres |
| GB9807721D0 (en) | 1998-04-08 | 1998-06-10 | Chiron Spa | Antigen |
| HUP0101619A3 (en) | 1998-04-09 | 2003-11-28 | Smithkline Beecham Biolog | Adjuvant compositions |
| CN100379757C (zh) | 1998-05-01 | 2008-04-09 | 希龙公司 | 脑膜炎奈瑟球菌抗原和组合物 |
| DE69930642T2 (de) | 1998-07-29 | 2006-12-28 | Chiron Corp., Emeryville | Mikropartikel mit adsorbenten oberflächen, verfahren zu ihrer herstellung und ihrer verwendung |
| JP2004511201A (ja) | 1998-10-09 | 2004-04-15 | カイロン コーポレイション | ナイセリアゲノム配列およびそれらの使用方法 |
| DE122007000087I1 (de) | 1998-10-16 | 2008-03-27 | Glaxosmithkline Biolog Sa | Adjuvanzsysteme und impfstoffe |
| AU1722300A (en) | 1998-11-12 | 2000-05-29 | Regents Of The University Of California, The | Chlamydia pneumoniae genome sequence |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| AU768574B2 (en) | 1999-02-01 | 2003-12-18 | Eisai R&D Management Co., Ltd. | Immunological adjuvant compound |
| CA2363141C (en) | 1999-02-26 | 2010-04-06 | Novartis Vaccines And Diagnostics, Inc. | Microemulsions with adsorbed macromolecules and microparticles |
| KR100642044B1 (ko) | 1999-03-19 | 2006-11-10 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 백신 |
| ATE403436T1 (de) | 1999-03-24 | 2008-08-15 | Secr Defence | Polykationische karbohydrate als immunostimulierende mittel in impstoffen |
| EP1165796A2 (en) | 1999-04-09 | 2002-01-02 | Techlab, Inc. | Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines |
| CN1227030C (zh) | 1999-04-19 | 2005-11-16 | 史密丝克莱恩比彻姆生物有限公司 | 包含皂甙和免疫刺激寡核苷酸的佐剂组合物 |
| PL355163A1 (en) | 1999-09-24 | 2004-04-05 | Smithkline Beecham Biologicals S.A. | Use of combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines |
| BR0014285A (pt) | 1999-09-24 | 2002-05-21 | Smithkline Beecham Biolog | Adjuvantes compreendendo um éster ou éter de alquila de polioxietileno e pelo menos um tensoativo não-iÈnico |
| DE60029243T2 (de) | 1999-11-19 | 2007-05-31 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Transfektion und aktivierung von dendritischen zellen durch mikropartikel |
| US7329408B2 (en) | 1999-12-01 | 2008-02-12 | Novartis Vaccines And Diagnostics, Inc. | Eliciting HCV-specific antibodies |
| CA2871789C (en) | 2000-01-17 | 2017-04-04 | Novartis Vaccines And Diagnostics S.R.L. | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins |
| AU2001249380A1 (en) | 2000-03-22 | 2001-11-07 | Chiron Corporation | Compositions and methods for generating an immune response utilizing alphavirus-based vector systems |
| US20040022814A1 (en) | 2000-06-15 | 2004-02-05 | O'hagan Derek | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| ATE440861T1 (de) | 2000-07-03 | 2009-09-15 | Novartis Vaccines & Diagnostic | Immunisierung gegen chlamydia pneumoniae |
| MXPA03002640A (es) | 2000-09-28 | 2003-06-19 | Chiron Corp | Microparticulas para la distribucion de acidos nucleicos heterologos. |
| JP2004509914A (ja) * | 2000-09-28 | 2004-04-02 | カイロン コーポレイション | 微粒子組成物およびその製造方法 |
| US7939087B2 (en) | 2000-10-27 | 2011-05-10 | Novartis Vaccines And Diagnostics, Inc. | Nucleic acids and proteins from Streptococcus groups A & B |
| ATE499948T1 (de) | 2001-01-12 | 2011-03-15 | Novartis Vaccines & Diagnostic | Nukleinsäure mukosale immunisierung |
| EP2957300B1 (en) * | 2001-01-23 | 2021-07-14 | Sanofi Pasteur Inc. | Multivalent meningococcal polysaccharide-protein conjugate vaccine |
| AU2002322358B2 (en) | 2001-06-29 | 2009-06-18 | Novartis Vaccines And Diagnostics, Inc. | HCV E1E2 vaccine compositions |
| AR045702A1 (es) | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
| US7838015B2 (en) | 2001-10-03 | 2010-11-23 | Novartis Vaccines And Diagnostics, Inc. | Adjuvanted meningococcus compositions |
| CA2462646C (en) | 2001-10-03 | 2013-02-12 | Chiron Corporation | Adjuvanted meningococcus compositions |
| WO2003070909A2 (en) | 2002-02-20 | 2003-08-28 | Chiron Corporation | Microparticles with adsorbed polypeptide-containing molecules |
| SE0201599D0 (sv) * | 2002-03-21 | 2002-05-30 | Skyepharma Ab | Microparticles |
| US7731967B2 (en) * | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
| US20090231609A1 (en) | 2005-06-29 | 2009-09-17 | Jan Chipchase | Smarter Printing |
-
2004
- 2004-06-02 CA CA2528007A patent/CA2528007C/en not_active Expired - Lifetime
- 2004-06-02 AT AT04776195T patent/ATE437633T2/de active
- 2004-06-02 DE DE602004022286T patent/DE602004022286D1/de not_active Expired - Lifetime
- 2004-06-02 ES ES09075251.0T patent/ES2596553T3/es not_active Expired - Lifetime
- 2004-06-02 CN CN2004800152668A patent/CN1798548B/zh not_active Expired - Lifetime
- 2004-06-02 JP JP2006515040A patent/JP5557415B2/ja not_active Expired - Lifetime
- 2004-06-02 PL PL04776195T patent/PL1631264T5/pl unknown
- 2004-06-02 US US10/858,858 patent/US9107831B2/en not_active Expired - Lifetime
- 2004-06-02 ES ES04776195.2T patent/ES2328697T5/es not_active Expired - Lifetime
- 2004-06-02 WO PCT/US2004/017125 patent/WO2005020964A1/en not_active Ceased
- 2004-06-02 EP EP04776195.2A patent/EP1631264B8/en not_active Expired - Lifetime
- 2004-06-02 EP EP09075251.0A patent/EP2179729B1/en not_active Expired - Lifetime
- 2004-06-02 PT PT04776195T patent/PT1631264E/pt unknown
-
2009
- 2009-10-15 CY CY091101079T patent/CY1109492T1/el unknown
-
2012
- 2012-01-27 JP JP2012014940A patent/JP2012082228A/ja not_active Withdrawn
-
2014
- 2014-03-19 JP JP2014056365A patent/JP2014111671A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006526649A5 (enExample) | ||
| CA2528007A1 (en) | Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen | |
| O’Hagan et al. | Microparticles as vaccine adjuvants and delivery systems | |
| JP2009518306A5 (enExample) | ||
| Shah et al. | Overview of vaccine adjuvants: introduction, history, and current status | |
| US6534064B1 (en) | Stabilized protein particles for inducing cellular immune responses | |
| AU2001294898B2 (en) | Microparticle compositions and methods for the manufacture thereof | |
| Vajdy et al. | Mucosal adjuvants and delivery systems for protein‐, DNA‐and RNA‐based vaccines | |
| JP5832485B2 (ja) | 吸着したポリペプチド含有分子を有する微粒子 | |
| Wendorf et al. | A comparison of anionic nanoparticles and microparticles as vaccine delivery systems | |
| EP1585542B1 (en) | Immunogenic compositions containing phospholipid | |
| JP2011506334A5 (enExample) | ||
| WO1998058668A2 (en) | Bordetella pertussis antigens as carriers in vaccinating conjugates and oral vaccines comprising bordetella pertussis fimbriae | |
| JP2008050374A (ja) | サブミクロンの水中油型エマルジョンと合わせた微粒子の使用 | |
| JP2002508334A5 (enExample) | ||
| JP6013400B2 (ja) | 免疫応答を誘導するための組成物 | |
| AU2001294898A1 (en) | Microparticle compositions and methods for the manufacture thereof | |
| JP4522699B2 (ja) | アジュバント化されたMeningococcus組成物 | |
| CA2731995C (en) | Method for inducing a cell-mediated immune response and parenteral vaccine formulations therefor | |
| US20150072016A1 (en) | Microparticles with adsorbed polynucleotide-containing species | |
| O’Hagan | New generation vaccine adjuvants | |
| CA2386023A1 (en) | Mucosal dtpa vaccines | |
| Kumar et al. | Chitosan microspheres as potential vaccine delivery systems | |
| JPWO2024071368A5 (enExample) |