JP2006515587A5 - - Google Patents
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- Publication number
- JP2006515587A5 JP2006515587A5 JP2004560041A JP2004560041A JP2006515587A5 JP 2006515587 A5 JP2006515587 A5 JP 2006515587A5 JP 2004560041 A JP2004560041 A JP 2004560041A JP 2004560041 A JP2004560041 A JP 2004560041A JP 2006515587 A5 JP2006515587 A5 JP 2006515587A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydrogen
- composition
- pharmaceutically acceptable
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- AYXYPKUFHZROOJ-ZETCQYMHSA-N CC(C)C[C@@H](CC(O)=O)CN Chemical compound CC(C)C[C@@H](CC(O)=O)CN AYXYPKUFHZROOJ-ZETCQYMHSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43349102P | 2002-12-13 | 2002-12-13 | |
| PCT/IB2003/005682 WO2004054563A1 (en) | 2002-12-13 | 2003-12-03 | Alpha-2-delta ligand for the treatment of sexual dysfunction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006515587A JP2006515587A (ja) | 2006-06-01 |
| JP2006515587A5 true JP2006515587A5 (https=) | 2006-10-12 |
Family
ID=32595199
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004560036A Pending JP2006511527A (ja) | 2002-12-13 | 2003-12-03 | 種々の薬学的用途のためのα２δリガンド |
| JP2004560041A Withdrawn JP2006515587A (ja) | 2002-12-13 | 2003-12-03 | 性的不能を治療する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004560036A Pending JP2006511527A (ja) | 2002-12-13 | 2003-12-03 | 種々の薬学的用途のためのα２δリガンド |
Country Status (15)
| Country | Link |
|---|---|
| US (8) | US7432299B2 (https=) |
| EP (2) | EP1572172A1 (https=) |
| JP (2) | JP2006511527A (https=) |
| KR (2) | KR100703103B1 (https=) |
| CN (8) | CN1726021A (https=) |
| AU (3) | AU2003303037A1 (https=) |
| BR (2) | BR0316753A (https=) |
| CA (3) | CA2451267A1 (https=) |
| MX (2) | MXPA05005665A (https=) |
| MY (1) | MY140525A (https=) |
| NZ (2) | NZ566452A (https=) |
| PL (2) | PL377729A1 (https=) |
| TW (2) | TWI286934B (https=) |
| WO (3) | WO2004054577A1 (https=) |
| ZA (6) | ZA200503862B (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL126999A (en) | 1996-07-24 | 2002-03-10 | Warner Lambert Co | Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain |
| US20050043406A1 (en) * | 2003-08-22 | 2005-02-24 | Pfizer Inc | Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss |
| US20050043407A1 (en) * | 2003-08-22 | 2005-02-24 | Pfizer Inc | Pharmaceutical composition for the prevention and treatment of addiction in a mammal |
| US20050043345A1 (en) * | 2003-08-22 | 2005-02-24 | Pfizer Inc | Pharmaceutical composition for the prevention and treatment of addiction in a mammal |
| BRPI0414798A (pt) | 2003-09-25 | 2006-11-21 | Warner Lambert Co | métodos para usar aminoácidos com afinidade para a proteìna alfa2delta |
| AR049384A1 (es) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
| EP2453024B1 (en) | 2004-06-21 | 2017-12-06 | The Board of Trustees of The Leland Stanford Junior University | Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder |
| ES2422893T3 (es) * | 2004-08-02 | 2013-09-16 | Sami Labs Limited | Composiciones y procedimientos para el tratamiento de las afecciones dermatológicas hiperproliferativas |
| PT1888548E (pt) | 2005-05-26 | 2012-10-30 | Neuron Systems Inc | Derivado de quinolina para o tratamento de doenças da retina |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| WO2007027476A2 (en) * | 2005-08-26 | 2007-03-08 | Xenoport, Inc. | Treating premature ejaculation using gabapentin and pregabalin prodrugs |
| DE102005050377A1 (de) * | 2005-10-21 | 2007-04-26 | Bayer Healthcare Ag | Heterocyclische Verbindungen und ihre Verwendung |
| WO2008073257A1 (en) * | 2006-12-08 | 2008-06-19 | Xenoport, Inc. | Use of prodrugs of gaba analogs for treating diseases |
| DE102007001804A1 (de) * | 2007-01-12 | 2008-07-17 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Verwendung von GABAB-Rezeptor selektiven Agonisten zur Behandlung entzündlicher Hauterkrankungen |
| CA2703472A1 (en) * | 2007-10-26 | 2009-04-30 | The Scripps Research Institute | Methods for treating substance dependence |
| AU2008318311B2 (en) * | 2007-11-02 | 2014-05-15 | The Board Of Trustees Of The Leland Stanford Junior University | FGF9-related methods for treating anxiety |
| CA2706575C (en) * | 2008-01-25 | 2015-07-14 | Xenoport, Inc. | Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs |
| US7868043B2 (en) | 2008-01-25 | 2011-01-11 | Xenoport, Inc. | Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use |
| EP2250148B1 (en) * | 2008-01-25 | 2016-08-17 | XenoPort, Inc. | Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use |
| JP2010043063A (ja) * | 2008-05-09 | 2010-02-25 | Agency For Science Technology & Research | 川崎病の診断及び治療 |
| WO2011072141A1 (en) | 2009-12-11 | 2011-06-16 | Neuron Systems, Inc. | Compositions and methods for the treatment of macular degeneration |
| CN102432525A (zh) * | 2011-10-20 | 2012-05-02 | 苏州康润医药有限公司 | 3-苄基-3-氮杂二环[2,1,0]己烷的实用合成方法 |
| RU2015120478A (ru) | 2012-12-20 | 2017-01-25 | Альдейра Терапьютикс, Инк. | Пери-карбинолы |
| US8992951B2 (en) * | 2013-01-09 | 2015-03-31 | Sapna Life Sciences Corporation | Formulations, procedures, methods and combinations thereof for reducing or preventing the development, or the risk of development, of neuropathology as a result of trauma |
| CA2898631C (en) | 2013-01-23 | 2023-06-13 | Aldeyra Therapeutics, Inc. | Toxic aldehyde related diseases and treatment |
| SG11201505599YA (en) | 2013-01-25 | 2015-08-28 | Aldeyra Therapeutics Inc | Novel traps in the treatment of macular degeneration |
| US10610512B2 (en) | 2014-06-26 | 2020-04-07 | Island Breeze Systems Ca, Llc | MDI related products and methods of use |
| ZA201603150B (en) * | 2015-05-12 | 2017-08-30 | Cipla Europe Nv | Inhaler device |
| CN118724806A (zh) | 2015-08-21 | 2024-10-01 | 奥尔德拉医疗公司 | 氘化化合物和其用途 |
| US11129823B2 (en) | 2016-05-09 | 2021-09-28 | Aldeyra Therapeutics, Inc. | Combination treatment of ocular inflammatory disorders and diseases |
| MX2019010576A (es) | 2017-03-16 | 2019-10-07 | Aldeyra Therapeutics Inc | Compuestos polimorficos y usos de los mismos. |
| KR102741262B1 (ko) | 2017-05-26 | 2024-12-11 | 노바쎄이 에스에이 | 전압-게이팅된 칼슘 채널 보조 서브유닛 α2δ 및 이의 용도 |
| JP7311162B2 (ja) | 2017-10-10 | 2023-07-19 | アルデイラ セラピューティクス， インコーポレイテッド | 炎症性障害の処置 |
| WO2020033344A1 (en) | 2018-08-06 | 2020-02-13 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| CN113784954A (zh) | 2019-05-02 | 2021-12-10 | 奥尔德拉医疗公司 | 多晶型化合物和其用途 |
| CN114599397B (zh) * | 2019-10-25 | 2024-05-28 | 国立大学法人京都大学 | Tau蛋白病的预防或治疗剂 |
| CA3175856A1 (en) | 2020-05-13 | 2021-11-18 | Todd Brady | Pharmaceutical formulations and uses thereof |
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| US2503059A (en) | 1950-04-04 | Nxchj | ||
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| IT1066857B (it) | 1965-12-15 | 1985-03-12 | Acraf | Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione |
| US3511836A (en) | 1967-12-13 | 1970-05-12 | Pfizer & Co C | 2,4,6,7-tetra substituted quinazolines |
| NL175059C (nl) | 1974-02-23 | Boehringer Mannheim Gmbh | Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten. | |
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| DE2460891C2 (de) | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
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| FR2421888A1 (fr) | 1978-02-06 | 1979-11-02 | Synthelabo | Amides d'alkylene-diamines et leur application en therapeutique |
| IT1094076B (it) | 1978-04-18 | 1985-07-26 | Acraf | Cicloalchiltriazoli |
| JPS56110665A (en) | 1980-02-08 | 1981-09-01 | Yamanouchi Pharmaceut Co Ltd | Sulfamoyl-substituted phenetylamine derivative and its preparation |
| US5084479A (en) * | 1990-01-02 | 1992-01-28 | Warner-Lambert Company | Novel methods for treating neurodegenerative diseases |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| US6197819B1 (en) | 1990-11-27 | 2001-03-06 | Northwestern University | Gamma amino butyric acid analogs and optical isomers |
| GB9117716D0 (en) * | 1991-08-16 | 1991-10-02 | Lynxvale Ltd | Gaba derivatives and their therapeutic application |
| JP3856816B2 (ja) | 1992-05-20 | 2006-12-13 | ノースウェスターン ユニヴァーシティ | 抗発作治療用のｇａｂａ及びｌ−グルタミン酸類縁体 |
| US5510381A (en) * | 1995-05-15 | 1996-04-23 | Warner-Lambert Company | Method of treatment of mania and bipolar disorder |
| GB9518953D0 (en) * | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
| EP0888325B1 (en) | 1996-02-07 | 2002-05-29 | Warner-Lambert Company | Novel cyclic amino acids as pharmaceutical agents |
| WO1997033859A1 (en) | 1996-03-14 | 1997-09-18 | Warner-Lambert Company | Novel bridged cyclic amino acids as pharmaceutical agents |
| HU224720B1 (en) | 1996-03-14 | 2006-01-30 | Warner Lambert Co | Novel substituted cyclic amino acid derivatives use as pharmaceutical agents |
| US6372792B1 (en) * | 1996-04-26 | 2002-04-16 | Guy Chouinard | Method for treating anxiety, anxiety disorders and insomnia |
| IL126999A (en) * | 1996-07-24 | 2002-03-10 | Warner Lambert Co | Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain |
| ATE361909T1 (de) | 1996-10-23 | 2007-06-15 | Warner Lambert Co | Substituierte gamma-aminobuttersäurederivate als arzneimittel |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| HRP980342A2 (en) * | 1997-06-25 | 1999-02-28 | Warner Lambert Co | Anti-inflammatory method |
| WO1999008670A1 (en) * | 1997-08-20 | 1999-02-25 | Guglietta, Antonio | Gaba analogs to prevent and treat gastrointestinal damage |
| ATE323067T1 (de) | 1997-10-27 | 2006-04-15 | Warner Lambert Co | Zyklische aminosäuren und deren derivate als arzneimittel |
| ES2258300T3 (es) | 1997-12-16 | 2006-08-16 | Pfizer Products Inc. | Combinacion de antagonistas del receptor alfa-1-adrenergico y un inhibidor gmpc pdev para el tratamiento de la impotencia. |
| CA2304967C (en) | 1997-12-16 | 2005-06-14 | Warner-Lambert Company | 4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders |
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| CN1131855C (zh) | 1997-12-16 | 2003-12-24 | 沃尼尔·朗伯公司 | 1－取代－1－氨基甲基－环烷衍生物(=加巴喷丁类似物)、其制备及其在治疗神经病方面的用途 |
| US5945117A (en) | 1998-01-30 | 1999-08-31 | Pentech Pharmaceuticals, Inc. | Treatment of female sexual dysfunction |
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| HN2000000224A (es) | 1999-10-20 | 2001-04-11 | Warner Lambert Co | Aminoacidos biciclicos como agentes farmaceuticos |
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| US6620829B2 (en) * | 2000-10-17 | 2003-09-16 | Warner-Lambert Company | Method of treating noninflammatory cartilage damage |
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| BR0115783A (pt) * | 2000-11-30 | 2003-09-16 | Pfizer Prod Inc | Combinação de agonistas de gaba e inibidores de sorbitol desidrogenase |
| SK12822003A3 (sk) | 2001-04-19 | 2004-04-06 | Warner - Lambert Company Llc | Fúzne bicyklické alebo tricyklické aminokyseliny |
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-
2003
- 2003-11-27 CA CA002451267A patent/CA2451267A1/en not_active Abandoned
- 2003-12-02 US US10/726,878 patent/US7432299B2/en not_active Expired - Fee Related
- 2003-12-03 PL PL377729A patent/PL377729A1/pl not_active Application Discontinuation
- 2003-12-03 CN CNA2003801060090A patent/CN1726021A/zh active Pending
- 2003-12-03 WO PCT/IB2003/005640 patent/WO2004054577A1/en not_active Ceased
- 2003-12-03 EP EP03813228A patent/EP1572172A1/en not_active Ceased
- 2003-12-03 CA CA002509611A patent/CA2509611A1/en not_active Abandoned
- 2003-12-03 WO PCT/IB2003/005682 patent/WO2004054563A1/en not_active Ceased
- 2003-12-03 BR BR0316753-4A patent/BR0316753A/pt not_active IP Right Cessation
- 2003-12-03 CN CNB2003801047024A patent/CN100367946C/zh not_active Expired - Fee Related
- 2003-12-03 KR KR1020057010548A patent/KR100703103B1/ko not_active Expired - Fee Related
- 2003-12-03 CN CNA2003801059680A patent/CN1726015A/zh active Pending
- 2003-12-03 CN CNA2003801060137A patent/CN1726023A/zh active Pending
- 2003-12-03 PL PL377656A patent/PL377656A1/pl not_active Application Discontinuation
- 2003-12-03 WO PCT/IB2003/005669 patent/WO2004054559A1/en not_active Ceased
- 2003-12-03 CN CNB2003801052910A patent/CN100430048C/zh not_active Expired - Fee Related
- 2003-12-03 BR BR0317273-2A patent/BR0317273A/pt not_active IP Right Cessation
- 2003-12-03 CN CNA200710110291XA patent/CN101283995A/zh active Pending
- 2003-12-03 EP EP03775689A patent/EP1572183A1/en not_active Withdrawn
- 2003-12-03 CN CNA2003801059657A patent/CN1726022A/zh active Pending
- 2003-12-03 CA CA002509600A patent/CA2509600A1/en not_active Abandoned
- 2003-12-03 AU AU2003303037A patent/AU2003303037A1/en not_active Abandoned
- 2003-12-03 MX MXPA05005665A patent/MXPA05005665A/es unknown
- 2003-12-03 JP JP2004560036A patent/JP2006511527A/ja active Pending
- 2003-12-03 MX MXPA05006318A patent/MXPA05006318A/es unknown
- 2003-12-03 CN CNA2008102138044A patent/CN101417129A/zh active Pending
- 2003-12-03 JP JP2004560041A patent/JP2006515587A/ja not_active Withdrawn
- 2003-12-03 NZ NZ566452A patent/NZ566452A/en not_active IP Right Cessation
- 2003-12-03 KR KR1020057010589A patent/KR20050085537A/ko not_active Ceased
- 2003-12-03 AU AU2003283708A patent/AU2003283708A1/en not_active Abandoned
- 2003-12-03 AU AU2003303038A patent/AU2003303038B2/en not_active Ceased
- 2003-12-03 NZ NZ539971A patent/NZ539971A/en unknown
- 2003-12-09 US US10/731,605 patent/US20040132636A1/en not_active Abandoned
- 2003-12-10 MY MYPI20034741A patent/MY140525A/en unknown
- 2003-12-12 TW TW092135262A patent/TWI286934B/zh not_active IP Right Cessation
- 2003-12-12 US US10/735,398 patent/US20040143014A1/en not_active Abandoned
- 2003-12-12 TW TW092135260A patent/TW200412241A/zh unknown
-
2005
- 2005-05-13 ZA ZA200503862A patent/ZA200503862B/en unknown
- 2005-05-13 ZA ZA200503861A patent/ZA200503861B/en unknown
- 2005-05-13 ZA ZA200503863A patent/ZA200503863B/en unknown
- 2005-05-25 ZA ZA200504271A patent/ZA200504271B/en unknown
- 2005-05-31 ZA ZA200504475A patent/ZA200504475B/en unknown
- 2005-06-09 ZA ZA200504724A patent/ZA200504724B/xx unknown
-
2007
- 2007-02-15 US US11/675,389 patent/US20070293570A1/en not_active Abandoned
- 2007-03-19 US US11/688,001 patent/US20070161707A1/en not_active Abandoned
- 2007-03-19 US US11/687,978 patent/US20070213401A1/en not_active Abandoned
- 2007-03-19 US US11/687,993 patent/US20070276039A1/en not_active Abandoned
- 2007-03-19 US US11/687,964 patent/US20070161706A1/en not_active Abandoned
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