JP2009524675A5 - - Google Patents

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Publication number
JP2009524675A5
JP2009524675A5 JP2008552415A JP2008552415A JP2009524675A5 JP 2009524675 A5 JP2009524675 A5 JP 2009524675A5 JP 2008552415 A JP2008552415 A JP 2008552415A JP 2008552415 A JP2008552415 A JP 2008552415A JP 2009524675 A5 JP2009524675 A5 JP 2009524675A5
Authority
JP
Japan
Prior art keywords
bioavailability
tetracycline compound
hydrogen
use according
enhancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008552415A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009524675A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/002081 external-priority patent/WO2007087416A2/en
Publication of JP2009524675A publication Critical patent/JP2009524675A/ja
Publication of JP2009524675A5 publication Critical patent/JP2009524675A5/ja
Pending legal-status Critical Current

Links

JP2008552415A 2006-01-24 2007-01-24 テトラサイクリンの経口バイオアベイラビリティーを増加する方法 Pending JP2009524675A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76181906P 2006-01-24 2006-01-24
PCT/US2007/002081 WO2007087416A2 (en) 2006-01-24 2007-01-24 Methods of increasing oral bioavailability of tetracyclines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010013625A Division JP2010106043A (ja) 2006-01-24 2010-01-25 テトラサイクリンの経口バイオアベイラビリティーを増加する方法

Publications (2)

Publication Number Publication Date
JP2009524675A JP2009524675A (ja) 2009-07-02
JP2009524675A5 true JP2009524675A5 (https=) 2010-03-18

Family

ID=38181071

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008552415A Pending JP2009524675A (ja) 2006-01-24 2007-01-24 テトラサイクリンの経口バイオアベイラビリティーを増加する方法
JP2010013625A Pending JP2010106043A (ja) 2006-01-24 2010-01-25 テトラサイクリンの経口バイオアベイラビリティーを増加する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010013625A Pending JP2010106043A (ja) 2006-01-24 2010-01-25 テトラサイクリンの経口バイオアベイラビリティーを増加する方法

Country Status (6)

Country Link
US (2) US9078811B2 (https=)
EP (2) EP1991236A2 (https=)
JP (2) JP2009524675A (https=)
AU (2) AU2007208214B2 (https=)
CA (1) CA2639406A1 (https=)
WO (1) WO2007087416A2 (https=)

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US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20050143352A1 (en) 2003-07-09 2005-06-30 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
AU2004261143B2 (en) 2003-07-25 2009-11-05 Allergan Pharmaceuticals International Limited A doxycycline metal complex in a solid dosage form
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AU2006206359B2 (en) * 2005-01-21 2011-03-31 Allergan Pharmaceuticals International Limited A tetracycline metal complex in a solid dosage form
CA2597212A1 (en) 2005-02-04 2006-08-10 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
US20070093455A1 (en) * 2005-07-21 2007-04-26 Paul Abato 10-substituted tetracyclines and methods of use thereof
EP2431469A3 (en) * 2006-05-15 2012-05-30 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
WO2008079339A2 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
CA2892739A1 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
AU2008239606A1 (en) 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
CA2717703A1 (en) * 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof
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WO2009128913A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TWI680117B (zh) * 2008-05-19 2019-12-21 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
KR101746795B1 (ko) 2008-08-08 2017-06-13 테트라페이즈 파마슈티컬스, 인코포레이티드 Ｃ７-플루오로 치환된 테트라시클린 화합물
US20100190755A1 (en) * 2008-09-19 2010-07-29 Paul Abato Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment
WO2010129057A2 (en) 2009-05-08 2010-11-11 Tetraphase Pharmaceuticals, Inc. Tetracycline compounds
NO2470500T3 (https=) 2009-08-28 2018-03-03
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
NZ722096A (en) 2011-12-15 2016-11-25 Alkermes Pharma Ireland Ltd Prodrugs of secondary amine compounds
CA2883238C (en) 2012-08-31 2021-11-23 Tetraphase Pharmaceuticals, Inc. Tetracycline compounds
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
CA3018872A1 (en) * 2016-03-24 2017-09-28 Paratek Pharmaceuticals, Inc. Methods of treating a bacterial infection in a subject at risk of developing c. difficile infection
HUE066360T2 (hu) 2016-10-19 2024-07-28 Tetraphase Pharmaceuticals Inc Eravaciklin kristályformái
BR112019008897A2 (pt) 2016-11-01 2019-08-13 Paratek Pharm Innc método para tratar pneumonia bacteriana adquirida na comunidade.
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas
WO2023238143A1 (en) * 2022-06-11 2023-12-14 Gufic Biosciences Limited A freeze dried parenteral composition of omadacycline tosylate with improved stability

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EA013835B1 (ru) 2001-03-13 2010-08-30 Пэрэтек Фамэсьютикэлс, Инк. Замещенные соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния субъекта
EP1381372A2 (en) 2001-03-14 2004-01-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
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ES2551708T3 (es) 2002-01-08 2015-11-23 Paratek Pharmaceuticals, Inc. Compuestos de 4-desdimetilamino tetraciclina
EP1503981A4 (en) 2002-03-21 2007-08-15 Paratek Pharm Innc SUBSTITUTED TETRACYCLINE COMPOUNDS
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AU2004259661B2 (en) 2003-07-09 2011-11-10 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20050143352A1 (en) 2003-07-09 2005-06-30 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
US8758820B2 (en) * 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
WO2005046651A1 (en) * 2003-11-12 2005-05-26 Ranbaxy Laboratories Limited Liquid filled capsules of doxycycline
GB2414668B (en) 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system

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