|
US3511836A
(en)
|
1967-12-13 |
1970-05-12 |
Pfizer & Co C |
2,4,6,7-tetra substituted quinazolines
|
|
US4018830A
(en)
|
1969-09-22 |
1977-04-19 |
Merck & Co., Inc. |
Phenylthioaralkylamines
|
|
US3840597A
(en)
|
1971-02-24 |
1974-10-08 |
Riker Laboratories Inc |
Substituted 2-phenoxy alkane-sulfonanilides
|
|
JPS536156B2
(enExample)
|
1972-10-30 |
1978-03-04 |
|
|
|
NL175059C
(nl)
|
1974-02-23 |
|
Boehringer Mannheim Gmbh |
Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.
|
|
DE2460891C2
(de)
|
1974-12-21 |
1982-09-23 |
Gödecke AG, 1000 Berlin |
1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
|
|
US4026894A
(en)
|
1975-10-14 |
1977-05-31 |
Abbott Laboratories |
Antihypertensive agents
|
|
GB1561411A
(en)
|
1977-02-25 |
1980-02-20 |
Science Union & Cie |
2-phenoxyphenyl pyrrolidines and pharmaceutical compositions containing them
|
|
US4188390A
(en)
|
1977-11-05 |
1980-02-12 |
Pfizer Inc. |
Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
|
|
DE2756113A1
(de)
|
1977-12-16 |
1979-06-21 |
Thomae Gmbh Dr K |
Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
|
|
FR2421888A1
(fr)
|
1978-02-06 |
1979-11-02 |
Synthelabo |
Amides d'alkylene-diamines et leur application en therapeutique
|
|
JPS56110665A
(en)
|
1980-02-08 |
1981-09-01 |
Yamanouchi Pharmaceut Co Ltd |
Sulfamoyl-substituted phenetylamine derivative and its preparation
|
|
US4885367A
(en)
|
1987-11-19 |
1989-12-05 |
Taisho Pharmaceutical Co., Ltd. |
Sulfonanilide compounds
|
|
SE8800207D0
(sv)
|
1988-01-22 |
1988-01-22 |
Kabivitrum Ab |
Nya aminer, deras anvendning och framstellning
|
|
US5376645A
(en)
|
1990-01-23 |
1994-12-27 |
University Of Kansas |
Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
|
|
KR0166088B1
(ko)
|
1990-01-23 |
1999-01-15 |
. |
수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
|
|
GB9013750D0
(en)
|
1990-06-20 |
1990-08-08 |
Pfizer Ltd |
Therapeutic agents
|
|
US6197819B1
(en)
|
1990-11-27 |
2001-03-06 |
Northwestern University |
Gamma amino butyric acid analogs and optical isomers
|
|
ZA923283B
(en)
|
1991-05-29 |
1993-01-27 |
Akzo Nv |
Phenoxyphenyl derivatives
|
|
GB9114760D0
(en)
|
1991-07-09 |
1991-08-28 |
Pfizer Ltd |
Therapeutic agents
|
|
GB9117716D0
(en)
*
|
1991-08-16 |
1991-10-02 |
Lynxvale Ltd |
Gaba derivatives and their therapeutic application
|
|
PT100905A
(pt)
|
1991-09-30 |
1994-02-28 |
Eisai Co Ltd |
Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
|
|
GB9121028D0
(en)
|
1991-10-03 |
1991-11-13 |
Pfizer Ltd |
Therapeutic agents
|
|
GB9126260D0
(en)
|
1991-12-11 |
1992-02-12 |
Pfizer Ltd |
Therapeutic agents
|
|
FR2687155B1
(fr)
|
1992-02-12 |
1995-05-19 |
Roussel Uclaf |
Nouveaux derives hexapeptidiques, procede de preparation et application a titre de medicaments de ces nouveaux derives.
|
|
IT1254469B
(it)
*
|
1992-02-25 |
1995-09-25 |
Recordati Chem Pharm |
Derivati benzopiranici e benzotiopiranici
|
|
ES2165857T3
(es)
|
1992-05-20 |
2002-04-01 |
Univ Northwestern |
Analogos de gaba y acido l-glutamico para el tratamiento de trastornos del sistema nervioso central.
|
|
GB9213623D0
(en)
|
1992-06-26 |
1992-08-12 |
Pfizer Ltd |
Therapeutic agents
|
|
GB9218322D0
(en)
|
1992-08-28 |
1992-10-14 |
Pfizer Ltd |
Therapeutic agents
|
|
DE69301894T2
(de)
|
1992-10-28 |
1996-11-07 |
Shionogi & Co |
Benzylidenderivate
|
|
EP0600675B1
(en)
|
1992-12-02 |
1998-07-08 |
Kissei Pharmaceutical Co., Ltd. |
Indoline compounds for the treatment of dysuria
|
|
WO1994015932A1
(en)
|
1993-01-15 |
1994-07-21 |
G.D. Searle & Co. |
Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
|
|
CA2113787A1
(en)
|
1993-01-29 |
1994-07-30 |
Nobuyuki Hamanaka |
Carbocyclic sulfonamides
|
|
US5380738A
(en)
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
|
US5344991A
(en)
|
1993-10-29 |
1994-09-06 |
G.D. Searle & Co. |
1,2 diarylcyclopentenyl compounds for the treatment of inflammation
|
|
NZ276885A
(en)
|
1993-11-30 |
1999-08-30 |
Searle & Co |
Substituted pyrazolyl-benzenesulphonamide derivatives, preparation and pharmaceutical compositions thereof
|
|
US5475018A
(en)
|
1993-11-30 |
1995-12-12 |
G. D. Searle & Co. |
1,5-diphenyl pyrazole compounds for treatment of inflammation
|
|
US5466823A
(en)
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
|
US6143746A
(en)
|
1994-01-21 |
2000-11-07 |
Icos Corporation |
Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use
|
|
GB9401090D0
(en)
|
1994-01-21 |
1994-03-16 |
Glaxo Lab Sa |
Chemical compounds
|
|
AU688498B2
(en)
|
1994-04-14 |
1998-03-12 |
Merck & Co., Inc. |
Alpha1c adrenergic receptor antagonists
|
|
WO1995030652A1
(en)
|
1994-05-04 |
1995-11-16 |
G.D. Searle & Co. |
Substituted spirodienes for the treatment of inflammation
|
|
US5418254A
(en)
|
1994-05-04 |
1995-05-23 |
G. D. Searle & Co. |
Substituted cyclopentadienyl compounds for the treatment of inflammation
|
|
US5486534A
(en)
|
1994-07-21 |
1996-01-23 |
G. D. Searle & Co. |
3,4-substituted pyrazoles for the treatment of inflammation
|
|
EP0772606A1
(en)
|
1994-07-27 |
1997-05-14 |
G.D. SEARLE & CO. |
Substituted thiazoles for the treatment of inflammation
|
|
US5616601A
(en)
|
1994-07-28 |
1997-04-01 |
Gd Searle & Co |
1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation
|
|
US5620999A
(en)
|
1994-07-28 |
1997-04-15 |
Weier; Richard M. |
Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
|
|
US5521213A
(en)
|
1994-08-29 |
1996-05-28 |
Merck Frosst Canada, Inc. |
Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
|
|
US5547975A
(en)
|
1994-09-20 |
1996-08-20 |
Talley; John J. |
Benzopyranopyrazolyl derivatives for the treatment of inflammation
|
|
US5739166A
(en)
|
1994-11-29 |
1998-04-14 |
G.D. Searle & Co. |
Substituted terphenyl compounds for the treatment of inflammation
|
|
JP3181190B2
(ja)
|
1994-12-20 |
2001-07-03 |
日本たばこ産業株式会社 |
オキサゾール誘導体
|
|
JP2636819B2
(ja)
|
1994-12-20 |
1997-07-30 |
日本たばこ産業株式会社 |
オキサゾール系複素環式芳香族化合物
|
|
AU4700896A
(en)
|
1995-01-20 |
1996-08-07 |
G.D. Searle & Co. |
Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors
|
|
US5596008A
(en)
|
1995-02-10 |
1997-01-21 |
G. D. Searle & Co. |
3,4-Diaryl substituted pyridines for the treatment of inflammation
|
|
US5633272A
(en)
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
|
ATE223390T1
(de)
|
1995-02-13 |
2002-09-15 |
Searle & Co |
Substituierte isoxazole zur behandlung von entzündung
|
|
US5731343A
(en)
|
1995-02-24 |
1998-03-24 |
The Scripps Research Institute |
Method of use of radicicol for treatment of immunopathological disorders
|
|
US5698560A
(en)
|
1995-03-01 |
1997-12-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Imidazoquinazoline derivatives
|
|
US5604253A
(en)
|
1995-05-22 |
1997-02-18 |
Merck Frosst Canada, Inc. |
N-benzylindol-3-yl propanoic acid derivatives as cyclooxygenase inhibitors
|
|
EP0828718A1
(en)
|
1995-06-02 |
1998-03-18 |
G.D. SEARLE & CO. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
|
US5643933A
(en)
|
1995-06-02 |
1997-07-01 |
G. D. Searle & Co. |
Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
|
US5968974A
(en)
|
1995-07-19 |
1999-10-19 |
Merck & Co., Inc. |
Method of treating colonic adenomas
|
|
WO1997003668A1
(en)
|
1995-07-21 |
1997-02-06 |
Constantia Gruppe |
Treatment and prevention of neoplasms with salts of aminoimidazole carboxamide and 5-amino or substituted amino 1,2,3-triazoles
|
|
JPH11510485A
(ja)
|
1995-07-21 |
1999-09-14 |
ニィコメド・オーストリア・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
酵素のシクロオキシゲナーゼiiの阻害剤としてのベンゼンスルホンアミドの誘導体
|
|
GB9518953D0
(en)
|
1995-09-15 |
1995-11-15 |
Pfizer Ltd |
Pharmaceutical formulations
|
|
GB9520584D0
(en)
|
1995-10-09 |
1995-12-13 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
US5981576A
(en)
|
1995-10-13 |
1999-11-09 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
US6057319A
(en)
|
1995-10-30 |
2000-05-02 |
Merck Frosst Canada & Co. |
3,4-Diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to cox-2 inhibitors
|
|
CZ293595A3
(cs)
|
1995-11-09 |
1999-12-15 |
Farmak A. S. |
Deriváty N,N-dimethyl-2-(arylthio)benzylaminu, jejich soli, způsoby jejich přípravy a jejich použití v léčivých přípravcích
|
|
US6222048B1
(en)
|
1995-12-18 |
2001-04-24 |
Merck Frosst Canada & Co. |
Diaryl-2-(5H)-furanones as Cox-2 inhibitors
|
|
US5929088A
(en)
|
1996-02-07 |
1999-07-27 |
Warner-Lambert Company |
Cyclic amino acids as pharmaceutical agents
|
|
KR100512506B1
(ko)
|
1996-03-14 |
2005-12-21 |
워너-램버트 캄파니 엘엘씨 |
제약제제로서신규한치환시클릭아미노산
|
|
DE69709070T2
(de)
|
1996-03-14 |
2002-06-20 |
Warner-Lambert Co., Morris Plains |
Verbrückte zyklische aminosäuren als pharmazeutische mittel
|
|
US6180651B1
(en)
|
1996-04-04 |
2001-01-30 |
Bristol-Myers Squibb |
Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
|
|
US5908858A
(en)
|
1996-04-05 |
1999-06-01 |
Sankyo Company, Limited |
1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
|
|
SK285353B6
(sk)
|
1996-04-12 |
2006-11-03 |
G. D. Searle & Co. |
Substituované benzénsulfónamidy ako proliečivá COX-2 inhibítorov, farmaceutická kompozícia a spôsobich prípravy a použitia
|
|
US5883267A
(en)
|
1996-05-31 |
1999-03-16 |
Merck & Co., Inc. |
Process for making phenyl heterocycles useful as cox-2 inhibitors
|
|
US5861419A
(en)
|
1996-07-18 |
1999-01-19 |
Merck Frosst Canad, Inc. |
Substituted pyridines as selective cyclooxygenase-2 inhibitors
|
|
CZ292843B6
(cs)
|
1996-07-18 |
2003-12-17 |
Merck Frosst Canada & Co. |
Derivát pyridinu a farmaceutický prostředek s jeho obsahem
|
|
AU714980B2
(en)
|
1996-07-24 |
2000-01-13 |
Warner-Lambert Company Llc |
Isobutylgaba and its derivatives for the treatment of pain
|
|
PE92198A1
(es)
|
1996-08-01 |
1999-01-09 |
Banyu Pharma Co Ltd |
Derivados de 1,4-piperidina disustituida que contienen fluor
|
|
JP3978250B2
(ja)
*
|
1996-08-16 |
2007-09-19 |
株式会社フジモト・コーポレーション |
テストステロン5α−リダクターゼ阻害剤
|
|
DE69737719D1
(de)
|
1996-10-23 |
2007-06-21 |
Warner Lambert Co |
Substituierte gamma-aminobuttersäurederivate als arzneimittel
|
|
WO2000035298A1
(en)
|
1996-11-27 |
2000-06-22 |
Wm. Wrigley Jr. Company |
Chewing gum containing medicament active agents
|
|
GB9700504D0
(en)
|
1997-01-11 |
1997-02-26 |
Pfizer Ltd |
Pharmaceutical compounds
|
|
ATA16597A
(de)
|
1997-02-03 |
1998-04-15 |
Nycomed Austria Gmbh |
Neue substituierte p-sulfonylaminobenzol- sulfonsäureamide
|
|
JP4357004B2
(ja)
|
1997-04-11 |
2009-11-04 |
あすか製薬株式会社 |
ピラゾール誘導体およびそれを含有するcox阻害剤
|
|
US6130334A
(en)
|
1998-04-15 |
2000-10-10 |
Merck & Co., Inc. |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
|
|
US6127545A
(en)
|
1997-04-18 |
2000-10-03 |
Merck & Co., Inc. |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
|
|
US6077850A
(en)
|
1997-04-21 |
2000-06-20 |
G.D. Searle & Co. |
Substituted benzopyran analogs for the treatment of inflammation
|
|
US6034256A
(en)
|
1997-04-21 |
2000-03-07 |
G.D. Searle & Co. |
Substituted benzopyran derivatives for the treatment of inflammation
|
|
PL336586A1
(en)
*
|
1997-04-25 |
2000-07-03 |
Pfizer |
Pyrazoylpyrimidinones inhibiting the cyclic guanosine 3',5'-monophosphate phosphodiesterase of type 5 (cgmp pde5) for treating sexual disorders
|
|
US6043252A
(en)
|
1997-05-05 |
2000-03-28 |
Icos Corporation |
Carboline derivatives
|
|
GB9711643D0
(en)
|
1997-06-05 |
1997-07-30 |
Janssen Pharmaceutica Nv |
Glass thermoplastic systems
|
|
IL133766A0
(en)
|
1997-06-30 |
2001-04-30 |
Ortho Mcneil Pharm Inc |
2-substituted imidazoles useful in the treatment of inflammatory diseases
|
|
AP9801302A0
(en)
|
1997-07-23 |
2000-01-23 |
Pfizer |
Indole compounds as anti-inflammatory/analgesic agents..
|
|
AU8668598A
(en)
*
|
1997-08-20 |
1999-03-08 |
University Of Oklahoma, The |
Gaba analogs to prevent and treat gastrointestinal damage
|
|
US6307047B1
(en)
|
1997-08-22 |
2001-10-23 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
|
HU226165B1
(en)
*
|
1997-09-08 |
2008-05-28 |
Warner Lambert Co |
Analgesic compositions comprising anti-epileptic compounds and non-steroid anti-inflammatory dr4gs
|
|
US5925769A
(en)
|
1997-09-09 |
1999-07-20 |
Ortho Pharmaceutical, Corp. |
Acetylenic 1,5-diarylpyrazoles as antiinflammatory agents
|
|
US6046217A
(en)
|
1997-09-12 |
2000-04-04 |
Merck Frosst Canada & Co. |
2,3,5-trisubstituted pyridines as inhibitors of cyclooxygenase-2
|
|
US6140515A
(en)
|
1997-09-24 |
2000-10-31 |
Merck & Co., Inc. |
Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of COX-2
|
|
US6040450A
(en)
|
1997-09-25 |
2000-03-21 |
Merck & Co., Inc. |
Process for making diaryl pyridines useful as cox-2-inhibitors
|
|
HUP0004310A3
(en)
|
1997-10-27 |
2001-11-28 |
Warner Lambert Co |
Cyclic amino acids, and derivatives thereof and pharmaceutical compositions comprising the said compounds as active agents
|
|
US6080876A
(en)
|
1997-10-29 |
2000-06-27 |
Merck & Co., Inc. |
Process for making phenyl heterocycles useful as COX-2 inhibitors
|
|
US6133292A
(en)
|
1997-10-30 |
2000-10-17 |
Merck Frosst Canada & Co. |
Diaryl-5-alkyl-5-methyl-2-(5H)-furanones as selective cyclooxygenase-2-inhibitors
|
|
HRP20020585B1
(hr)
|
1997-11-12 |
2013-02-28 |
Bayer Schering Pharma Aktiengesellschaft |
2-fenil supstituirani imidazotriazinoni kao inhibitori fosfodiesteraze
|
|
SI1047678T1
(en)
|
1997-12-16 |
2005-02-28 |
Warner-Lambert Company Llc |
1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
|
|
HUP0100472A3
(en)
|
1997-12-16 |
2003-03-28 |
Warner Lambert Co |
Novel amines as pharmaceutical agents
|
|
EP1045834A1
(en)
|
1997-12-16 |
2000-10-25 |
Warner-Lambert Company |
4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
|
|
JP3256513B2
(ja)
|
1998-02-11 |
2002-02-12 |
ファイザー製薬株式会社 |
ベンゾイミダゾールシクロオキシゲナーゼ−2阻害剤
|
|
US5994379A
(en)
|
1998-02-13 |
1999-11-30 |
Merck Frosst Canada, Inc. |
Bisaryl COX-2 inhibiting compounds, compositions and methods of use
|
|
HUP0102543A3
(en)
|
1998-04-20 |
2002-01-28 |
Pfizer |
Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment of sexual dysfunction and medicaments containing them
|
|
AU3953899A
(en)
*
|
1998-05-27 |
1999-12-13 |
Nippon Shinyaku Co. Ltd. |
Cyclooxygenase-2 inhibitors
|
|
EP1085845A2
(en)
|
1998-06-08 |
2001-03-28 |
Advanced Medicine, Inc. |
Multibinding inhibitors of cyclooxygenase-2
|
|
EP0967777A3
(de)
|
1998-06-26 |
2000-01-05 |
Siemens Aktiengesellschaft |
Verfahren zur Übertragung von Informationen im Teilnehmeranschlussbereich
|
|
KR100295206B1
(ko)
|
1998-08-22 |
2001-07-12 |
서경배 |
디아릴벤조피란유도체및이를함유하는시클로옥시게네이즈-2저해제조성물
|
|
DE69942928D1
(de)
*
|
1998-08-27 |
2010-12-23 |
Pfizer Health Ab |
Therapeutische formulierung zur verabreichung von tolterodin mit kontrollierter freisetzung
|
|
WO2000015639A1
(en)
|
1998-09-16 |
2000-03-23 |
Icos Corporation |
Carboline derivatives as cgmp phosphodiesterase inhibitors
|
|
PT1123296E
(pt)
|
1998-10-23 |
2003-12-31 |
Pfizer |
Inibidores de cgmp pdes derivados da pirazolopirimidinona para tratamento da disfuncao sexual
|
|
GB9823103D0
(en)
|
1998-10-23 |
1998-12-16 |
Pfizer Ltd |
Pharmaceutically active compounds
|
|
GB9823101D0
(en)
|
1998-10-23 |
1998-12-16 |
Pfizer Ltd |
Pharmaceutically active compounds
|
|
JP2003512292A
(ja)
|
1998-10-27 |
2003-04-02 |
アボット・ラボラトリーズ |
プロスタグランジンエンドペルオキシドhシンターゼ生合成阻害剤
|
|
US6077869A
(en)
|
1998-10-29 |
2000-06-20 |
Ortho-Mcneil Pharmaceutical, Inc. |
Aryl phenylhydrazides as selective COX-2 inhibitors for treatment of inflammation
|
|
KR100353014B1
(ko)
|
1998-11-11 |
2002-09-18 |
동아제약 주식회사 |
발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
|
|
IL144309A0
(en)
|
1999-02-23 |
2002-05-23 |
Pfizer Prod Inc |
Monoamine reuptake inhibitors for treatment of cns disorders
|
|
ES2313880T3
(es)
*
|
1999-04-08 |
2009-03-16 |
Warner-Lambert Company Llc |
Procedimiento para el tratamiento de la icontinencia.
|
|
IL146969A0
(en)
|
1999-06-10 |
2002-08-14 |
Warner Lambert Co |
Mono- and disubstituted 3-propyl gamma-aminobutyric acids
|
|
CA2377153A1
(en)
|
1999-06-16 |
2000-12-21 |
Temple University - Of The Commonwealth System Of Higher Education |
1-(4-sulfamylaryl)-3-substituted-5-aryl-2-pyrazolines as inhibitors of cyclooxygenase-2
|
|
MXPA00006605A
(es)
|
1999-07-02 |
2004-12-09 |
Pfizer |
Compuestos de carbonil-indol biciclicos como agentes antiinflamatorios/analgesicos.
|
|
US6077868A
(en)
|
1999-07-20 |
2000-06-20 |
Wisconsin Alumni Research Foundation |
Selective inhibition of cyclooxygenase-2
|
|
US6306890B1
(en)
|
1999-08-30 |
2001-10-23 |
Vanderbilt University |
Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors
|
|
NZ517324A
(en)
|
1999-10-11 |
2003-09-26 |
Pfizer |
5-(2-substituted-5-heterocyclylsulphonylpyrid-3-YL)- dihydropyrazolo[4,3-d]pyrimidin-7-ones as phosphodiesterase inhibitors
|
|
US6503908B1
(en)
|
1999-10-11 |
2003-01-07 |
Pfizer Inc |
Pharmaceutically active compounds
|
|
TWI265925B
(en)
|
1999-10-11 |
2006-11-11 |
Pfizer |
Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
|
|
GB9924020D0
(en)
|
1999-10-11 |
1999-12-15 |
Pfizer Ltd |
Pharmaceutically active compounds
|
|
YU21602A
(sh)
|
1999-10-13 |
2005-06-10 |
Pfizer Products Inc. |
Derivati biaril etra korisni kao inhibitori ponovnog podizanja monoamina
|
|
HN2000000224A
(es)
|
1999-10-20 |
2001-04-11 |
Warner Lambert Co |
Aminoacidos biciclicos como agentes farmaceuticos
|
|
US6083969A
(en)
|
1999-10-20 |
2000-07-04 |
Ortho-Mcneil Pharaceutical, Inc. |
1,3- and 2,3-diarylcycloalkano and cycloalkeno pyrazoles as selective inhibitors of cyclooxygenase-2 and antiinflammatory agents
|
|
IL139073A0
(en)
*
|
1999-10-21 |
2001-11-25 |
Pfizer |
Treatment of neuropathy
|
|
NZ518309A
(en)
*
|
1999-11-11 |
2003-05-30 |
Pharmacia Ab |
Controlled release tolterodine formulation that releases not less than 80% of the active compound in under 18 hours
|
|
GB2362646A
(en)
|
2000-05-26 |
2001-11-28 |
Warner Lambert Co |
Cyclic amino acid derivatives useful as pharmaceutical agents
|
|
MXPA02012076A
(es)
|
2000-06-07 |
2003-06-06 |
Lilly Icos Llc |
Compuestos quimicos.
|
|
EP1289990A1
(en)
|
2000-06-08 |
2003-03-12 |
Lilly Icos LLC |
Tetracyclic diketopierazine compounds as pdev inhibitors
|
|
MXPA02012659A
(es)
|
2000-06-26 |
2003-09-22 |
Lilly Icos Llc |
Derivados de pirazindiona condensados.
|
|
DE10035718A1
(de)
|
2000-07-21 |
2002-02-07 |
Boehringer Werkzeugmaschinen |
Werkzeugmaschine
|
|
GB2365425A
(en)
|
2000-08-01 |
2002-02-20 |
Parke Davis & Co Ltd |
Alkyl amino acid derivatives useful as pharmaceutical agents
|
|
CA2423357C
(en)
|
2000-08-02 |
2008-05-27 |
Lilly Icos Llc |
Fused heterocyclic derivatives as phosphodiesterase inhibitors
|
|
ES2252310T3
(es)
|
2000-09-14 |
2006-05-16 |
Grunenthal Gmbh |
Beta-tioaminoacidos.
|
|
DE10048715A1
(de)
|
2000-09-30 |
2004-05-19 |
Grünenthal GmbH |
Verwendung von Aminosäure zur Behandlung von Schmerz
|
|
AR034160A1
(es)
|
2000-09-30 |
2004-02-04 |
Gruenenthal Gmbh |
Sulfonilguanidinas, medicamentos que contienen estos compuestos y el uso de sulfonilguanidinas
|
|
DE60111553T2
(de)
|
2000-10-02 |
2006-04-06 |
Lilly Icos Llc, Wilmington |
Hexahydropyrazino[1'2':1,6]-pyrido[3,4-b]indole-1,4-dion-derivate zur behandlung von cardiovaskulären erkrankungen und erektionsstörungen
|
|
AU2002213419A1
(en)
|
2000-10-02 |
2002-04-15 |
Lilly Icos Llc |
Condensed pyridoindole derivatives
|
|
JP4246488B2
(ja)
|
2000-10-03 |
2009-04-02 |
リリー アイコス リミテッド ライアビリティ カンパニー |
化学化合物
|
|
AU2002211863A1
(en)
|
2000-10-06 |
2002-04-15 |
Xenoport, Inc. |
Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration
|
|
GB2367869B
(en)
|
2000-10-14 |
2004-10-06 |
Trw Ltd |
Rear-axle demand for use with front push-through in electrohydraulic (EHB) braking systems
|
|
US6359182B1
(en)
|
2000-10-26 |
2002-03-19 |
Duke University |
C-nitroso compounds and use thereof
|
|
GB2368579A
(en)
|
2000-10-31 |
2002-05-08 |
Parke Davis & Co Ltd |
Azole pharmaceutical agents
|
|
CA2427573C
(en)
|
2000-11-06 |
2008-10-07 |
Lilly Icos Llc |
Indole derivatives as pde5-inhibitors
|
|
US6960587B2
(en)
|
2000-11-08 |
2005-11-01 |
Lilly Icos Llc |
Condensed pyrazindione derivatives as PDE inhibitors
|
|
WO2002042414A2
(en)
|
2000-11-17 |
2002-05-30 |
Xenoport, Inc. |
Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
|
|
EP1337272A2
(en)
*
|
2000-11-30 |
2003-08-27 |
Pfizer Products Inc. |
Combination of gaba agonists and aldose reductase inhibitors
|
|
US7022856B2
(en)
|
2001-02-12 |
2006-04-04 |
Lilly Icos Llc. |
Carboline derivatives
|
|
GB0105893D0
(en)
|
2001-03-09 |
2001-04-25 |
Pfizer Ltd |
Pharmaceutically active compounds
|
|
GB0106661D0
(en)
|
2001-03-16 |
2001-05-09 |
Pfizer Ltd |
Pharmaceutically active compounds
|
|
GB0106631D0
(en)
|
2001-03-16 |
2001-05-09 |
Pfizer Ltd |
Pharmaceutically active compounds
|
|
ATE298238T1
(de)
|
2001-03-16 |
2005-07-15 |
Pfizer |
Pyrazolo(4,3-d)pyrimidinon-verbindungen als cgmp pde-inhibitoren
|
|
HRP20030832A2
(en)
|
2001-04-19 |
2005-08-31 |
Warner-Lambert Company Llc |
Fused bicyclic or tricyclic amino acids
|
|
DE10127980C1
(de)
|
2001-06-08 |
2003-01-16 |
Ovd Kinegram Ag Zug |
Diffraktives Sicherheitselement
|
|
KR200245823Y1
(ko)
|
2001-06-08 |
2001-10-22 |
김영남 |
물감튜브가 달린 그림붓
|
|
AU2002345664C1
(en)
|
2001-06-11 |
2008-03-06 |
Xenoport, Inc. |
Prodrugs of gaba analogs, compositions and uses thereof
|
|
ITMI20011308A1
(it)
|
2001-06-21 |
2002-12-21 |
Nicox Sa |
Farmaci per il dolore cronico
|
|
WO2003070237A1
(en)
*
|
2002-02-22 |
2003-08-28 |
Warner-Lambert Company Llc |
Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2
|
|
US7892837B2
(en)
|
2002-05-23 |
2011-02-22 |
Karsten Koenig |
Method for transferring molecules in vital cells by means of laser beams and arrangement for carrying out said method
|
|
MXPA05006656A
(es)
|
2002-12-20 |
2006-02-22 |
Dynogen Pharmaceuticals Inc |
Metodos de tratamiento de desordenes de vejiga no dolorosos usando moduladores del canal de calcio subunidad (2o.
|
|
EP1492519B1
(en)
*
|
2003-03-21 |
2006-11-15 |
Dynogen Pharmaceuticals, Inc. |
Methods for treating lower urinary tract disorders using antimuscarinics and alpha-2-delta subunit calcium channel modulators
|
|
CN112585695B
(zh)
|
2018-08-16 |
2025-05-16 |
生命技术公司 |
用于自动化试剂验证的系统和方法
|