JP2005503125A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005503125A5 JP2005503125A5 JP2002582208A JP2002582208A JP2005503125A5 JP 2005503125 A5 JP2005503125 A5 JP 2005503125A5 JP 2002582208 A JP2002582208 A JP 2002582208A JP 2002582208 A JP2002582208 A JP 2002582208A JP 2005503125 A5 JP2005503125 A5 JP 2005503125A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid sequence
- seq
- protein
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 53
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 35
- 108090000623 proteins and genes Proteins 0.000 claims 20
- 102000004169 proteins and genes Human genes 0.000 claims 18
- 125000003275 alpha amino acid group Chemical group 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 16
- 102000039446 nucleic acids Human genes 0.000 claims 16
- 108010000700 Acetolactate synthase Proteins 0.000 claims 12
- 238000000034 method Methods 0.000 claims 9
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 108010030975 Polyketide Synthases Proteins 0.000 claims 7
- 244000005700 microbiome Species 0.000 claims 7
- 102000004243 Tubulin Human genes 0.000 claims 5
- 108090000704 Tubulin Proteins 0.000 claims 5
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 4
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- BCIHMWNOJJYBSJ-UHFFFAOYSA-N 2-pyrimidin-2-yloxybenzoic acid Chemical compound OC(=O)C1=CC=CC=C1OC1=NC=CC=N1 BCIHMWNOJJYBSJ-UHFFFAOYSA-N 0.000 claims 3
- CAAMSDWKXXPUJR-UHFFFAOYSA-N 3,5-dihydro-4H-imidazol-4-one Chemical compound O=C1CNC=N1 CAAMSDWKXXPUJR-UHFFFAOYSA-N 0.000 claims 3
- 239000003112 inhibitor Substances 0.000 claims 3
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 claims 3
- 230000002103 transcriptional effect Effects 0.000 claims 3
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 claims 2
- 101710123462 Bleomycin resistance protein Proteins 0.000 claims 2
- 235000021294 Docosapentaenoic acid Nutrition 0.000 claims 2
- 102000009114 Fatty acid desaturases Human genes 0.000 claims 2
- 108010087894 Fatty acid desaturases Proteins 0.000 claims 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 2
- 235000021342 arachidonic acid Nutrition 0.000 claims 2
- 229940114079 arachidonic acid Drugs 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 2
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 2
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 2
- 230000006801 homologous recombination Effects 0.000 claims 2
- 238000002744 homologous recombination Methods 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 230000035945 sensitivity Effects 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 230000009466 transformation Effects 0.000 claims 2
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 claims 1
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 claims 1
- 241001467333 Thraustochytriaceae Species 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28411601P | 2001-04-16 | 2001-04-16 | |
| PCT/US2002/012040 WO2002083869A2 (en) | 2001-04-16 | 2002-04-16 | Product and process for transformation of thraustochytriales microorganisms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010019881A Division JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005503125A JP2005503125A (ja) | 2005-02-03 |
| JP2005503125A5 true JP2005503125A5 (https=) | 2005-12-22 |
| JP4536324B2 JP4536324B2 (ja) | 2010-09-01 |
Family
ID=23088908
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002582208A Expired - Fee Related JP4536324B2 (ja) | 2001-04-16 | 2002-04-16 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2010019881A Expired - Lifetime JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2012215905A Withdrawn JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2015253726A Expired - Fee Related JP6211577B2 (ja) | 2001-04-16 | 2015-12-25 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010019881A Expired - Lifetime JP5248536B2 (ja) | 2001-04-16 | 2010-02-01 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2012215905A Withdrawn JP2013005817A (ja) | 2001-04-16 | 2012-09-28 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
| JP2015253726A Expired - Fee Related JP6211577B2 (ja) | 2001-04-16 | 2015-12-25 | トラウストチトリアレス微生物の形質転換についての産物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7001772B2 (https=) |
| EP (3) | EP2325319B1 (https=) |
| JP (4) | JP4536324B2 (https=) |
| CN (3) | CN101760469A (https=) |
| AT (1) | ATE533844T1 (https=) |
| AU (1) | AU2002250592C1 (https=) |
| CA (1) | CA2443908C (https=) |
| ES (3) | ES2377557T3 (https=) |
| TW (3) | TWI377253B (https=) |
| WO (1) | WO2002083869A2 (https=) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US8003772B2 (en) * | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| TWI377253B (en) * | 2001-04-16 | 2012-11-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7211656B2 (en) * | 2002-01-30 | 2007-05-01 | Abbott Laboratories | Desaturase genes, enzymes encoded thereby, and uses thereof |
| ATE354645T1 (de) * | 2002-12-20 | 2007-03-15 | Chromagenics Bv | Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können |
| US7208590B2 (en) * | 2003-07-15 | 2007-04-24 | Abbott Laboratories | Genes involved in polyketide synthase pathways and uses thereof |
| CN103451246B (zh) | 2004-04-22 | 2018-02-16 | 联邦科学技术研究组织 | 用重组细胞合成长链多不饱和脂肪酸 |
| EP2357244A3 (en) | 2004-04-22 | 2011-11-23 | Commonwealth Scientific and Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells. |
| EP1809750B1 (en) * | 2004-11-08 | 2012-03-21 | ChromaGenics B.V. | Selection of host cells expressing protein at high levels |
| US8999667B2 (en) * | 2004-11-08 | 2015-04-07 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20060195935A1 (en) | 2004-11-08 | 2006-08-31 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20100136616A1 (en) * | 2004-11-08 | 2010-06-03 | Chromagenics B.V. | Selection of Host Cells Expressing Protein at High Levels |
| US20060172382A1 (en) * | 2004-11-08 | 2006-08-03 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| JP4796787B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
| JP4796786B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
| AU2006325040B2 (en) | 2005-06-07 | 2012-04-19 | Dsm Nutritional Products Ag | Eukaryotic microorganisms for producing lipids and antioxidants |
| AU2006316610B2 (en) | 2005-11-23 | 2012-06-14 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| EP1818411A1 (en) * | 2006-02-13 | 2007-08-15 | Lonza AG | Process for the preparation of optically active chiral amines |
| WO2007106905A2 (en) * | 2006-03-15 | 2007-09-20 | Martek Biosciences Corporation | Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems |
| KR20090007407A (ko) * | 2006-04-11 | 2009-01-16 | 마텍 바이오싸이언스스 코포레이션 | 장쇄 다중불포화 지방산을 포함하는 식품 제품 및 그의 제조 방법 |
| EP2034973B2 (en) | 2006-06-22 | 2022-01-19 | DSM IP Assets B.V. | Encapsulated labile compound compositions and methods of making the same |
| CA2659603C (en) * | 2006-08-01 | 2017-03-07 | Ocean Nutrition Canada Limited | Oil producing microbes and methods of modification thereof |
| RU2009111266A (ru) | 2006-08-29 | 2010-10-10 | Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) | Синтез жирных кислот |
| EP2415360A3 (en) | 2006-08-29 | 2012-02-29 | Martek Biosciences Corporation | Use of DPA(n-6) oils in infant formula |
| KR100860111B1 (ko) * | 2006-10-02 | 2008-09-25 | 인제대학교 산학협력단 | 신규 미생물 트라우스토카이트리움 에스피.케이제이에스-1, 바실러스 폴리퍼멘티쿠스 케이제이에스-2 및 이들과 바실러스 리케니포르미스를 포함하고 있는 사료첨가제 및 사료 |
| EP2082050B1 (en) | 2006-10-23 | 2013-04-24 | E.I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
| US8188338B2 (en) | 2007-04-10 | 2012-05-29 | E. I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
| US8119860B2 (en) | 2007-04-16 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| US8957280B2 (en) | 2007-05-03 | 2015-02-17 | E. I. Du Pont De Nemours And Company | Delta-5 desaturases and their use in making polyunsaturated fatty acids |
| AU2008269989B2 (en) * | 2007-06-29 | 2014-02-27 | Dsm Ip Assets B.V. | Production and purification of esters of polyunsaturated fatty acids |
| US20090064567A1 (en) | 2007-09-12 | 2009-03-12 | Martek Biosciences Corporation | Biological oils and production and uses Thereof |
| US20110076379A1 (en) * | 2008-06-13 | 2011-03-31 | Means Michael M | High omega saturated fat free meat products |
| BRPI0921467B1 (pt) | 2008-11-18 | 2021-12-14 | Commonwealth Scientific And Industrial Research Organisation | Processo para a produção de óleo compreendendo ácido eicosapentaenóico (epa), ácido docosapentaenóico (dpa) e ácido docosahexaenóico (dha) |
| AU2009335903B2 (en) | 2008-12-18 | 2016-04-14 | E. I. Du Pont De Nemours And Company | Reducing byproduction of malonates in a fermentation process |
| JP5415896B2 (ja) | 2009-01-29 | 2014-02-12 | Ｊｆｅスチール株式会社 | インダイレクトスポット溶接方法 |
| ES2752196T3 (es) * | 2009-03-16 | 2020-04-03 | Dsm Ip Assets Bv | Producción de proteínas en microorganismos del filo Labyrinthulomycota |
| US8207363B2 (en) | 2009-03-19 | 2012-06-26 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| US8940884B2 (en) | 2009-03-19 | 2015-01-27 | Dsm Ip Assets B.V. | Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof |
| CA2763424C (en) | 2009-06-16 | 2018-06-12 | E.I. Du Pont De Nemours And Company | Improvement of long chain omega-3 and omega-6 polyunsaturated fatty acid biosynthesis by expression of acyl-coa lysophospholipid acyltransferases |
| WO2011037207A1 (ja) * | 2009-09-24 | 2011-03-31 | 国立大学法人九州大学 | ストラメノパイルの形質転換方法 |
| CN103068965A (zh) | 2009-12-28 | 2013-04-24 | Dsmip资产公司 | 在蔗糖上生长的重组破囊壶菌和其组合物、制备方法及用途 |
| CN103260643A (zh) * | 2009-12-28 | 2013-08-21 | 梅里亚有限公司 | 重组ndv抗原及其用途 |
| EP2519636B8 (en) * | 2009-12-28 | 2017-08-09 | DSM IP Assets B.V. | Production of hemagglutinin-neuraminidase protein in microalgae |
| ES2651313T3 (es) * | 2009-12-28 | 2018-01-25 | Dsm Ip Assets B.V. | Traustoquítridos recombinantes que crecen en xilosa, y composiciones, métodos de preparación y usos de los mismos |
| IN2012DN06277A (https=) * | 2009-12-28 | 2015-09-25 | Dsm Ip Assets Bv | |
| US9924733B2 (en) * | 2010-01-19 | 2018-03-27 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| ES2617743T3 (es) | 2010-03-12 | 2017-06-19 | Merial, Inc. | Vacunas recombinantes del virus de la lengua azul y sus utilizaciones |
| KR20140008295A (ko) | 2010-08-26 | 2014-01-21 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 돌연변이 델타-9 연장효소 및 다중불포화 지방산의 제조에서의 그들의 용도 |
| JP2013535988A (ja) | 2010-08-26 | 2013-09-19 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 変異ｈｐｇｇモチーフおよびｈｄａｓｈモチーフδ５デサチュラーゼおよび多価不飽和脂肪酸の製造におけるそれらの使用 |
| PT2683824T (pt) * | 2011-03-07 | 2018-06-07 | Dsm Nutritional Products Ag | Modificação de microorganismos thraustochytrid |
| AU2012285806B2 (en) | 2011-07-21 | 2017-09-14 | Dsm Ip Assets B.V. | Fatty acid compositions |
| US8844424B2 (en) * | 2011-08-17 | 2014-09-30 | Lwrc International Llc | Bolt carrier and bolt for gas operated firearms |
| US8950312B2 (en) * | 2011-08-17 | 2015-02-10 | Lwrc International Llc | Bolt carrier and bolt for gas operated firearms |
| WO2013185184A2 (en) | 2012-06-15 | 2013-12-19 | Commonwealth Scientific And Industrial Research Organisation | Production of long chain polyunsaturated fatty acids in plant cells |
| CA2877334A1 (en) | 2012-06-19 | 2013-12-27 | E. I. Du Pont De Nemours And Company | Mutant acyl-coa:lysophosphatidylcholine acyltransferases |
| EP2970926B1 (en) | 2013-03-13 | 2018-01-31 | DSM Nutritional Products AG | Engineering microorganisms |
| EP3082405A4 (en) | 2013-12-18 | 2017-12-13 | Commonwealth Scientific and Industrial Research Organisation | Lipid comprising long chain polyunsaturated fatty acids |
| SG11201610596PA (en) | 2014-06-27 | 2017-01-27 | Commw Scient Ind Res Org | Lipid comprising docosapentaenoic acid |
| CN105567715B (zh) * | 2014-10-17 | 2021-06-29 | 丰益(上海)生物技术研发中心有限公司 | 裂殖壶菌α-微管蛋白相关序列及其应用 |
| CA2977271A1 (en) | 2015-03-02 | 2016-09-09 | Synthetic Genomics, Inc. | Regulatory elements from labyrinthulomycetes microorganisms |
| AR104042A1 (es) | 2015-03-26 | 2017-06-21 | Mara Renewables Corp | Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto |
| CN107846857B (zh) | 2015-06-06 | 2021-07-02 | 帝斯曼知识产权资产管理有限公司 | 使用新模块二十二碳六烯酸(dha)合酶生成多不饱和脂肪酸(pufas) |
| US10542961B2 (en) | 2015-06-15 | 2020-01-28 | The Research Foundation For The State University Of New York | System and method for infrasonic cardiac monitoring |
| EP3322796A4 (en) | 2015-07-13 | 2019-03-27 | Mara Renewables Corporation | IMPROVEMENT OF MICROGENONAL FLUID CHANGES OF XYLOSE |
| IL241462A0 (en) | 2015-09-10 | 2015-11-30 | Yeda Res & Dev | Heterologous engineering of betalain pigments in plants |
| EP3795586A3 (en) | 2016-03-16 | 2021-06-23 | Conagen Inc. | Production of proteins in labyrinthulomycetes |
| PL3455351T3 (pl) * | 2016-05-12 | 2022-11-21 | Dsm Ip Assets B.V. | Sposób zwiększania wytwarzania wielonienasyconych kwasów tłuszczowych omega-3 w mikroalgach |
| US10851395B2 (en) | 2016-06-10 | 2020-12-01 | MARA Renewables Corporation | Method of making lipids with improved cold flow properties |
| KR102319845B1 (ko) | 2016-07-13 | 2021-11-01 | 디에스엠 아이피 어셋츠 비.브이. | 조류 숙주 세포에 대한 crispr-cas 시스템 |
| IL247752A0 (en) | 2016-09-11 | 2016-11-30 | Yeda Res & Dev | Compositions and methods for modulating gene expression for site-directed mutagenesis |
| US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
| WO2019078359A1 (ja) | 2017-10-19 | 2019-04-25 | 味の素株式会社 | ステロールの製造法 |
| EP3762485A4 (en) * | 2018-03-05 | 2021-12-08 | Conagen Inc. | ORGANISMS AND METHOD FOR MANUFACTURING GLYCOMOLECULES WITH LOW SULFATION |
| CN112074608A (zh) * | 2018-05-01 | 2020-12-11 | 科纳根公司 | 用于产生具有高聚糖占有率的糖分子的重组生物体和方法 |
| BR112021002300A2 (pt) * | 2018-08-10 | 2021-05-04 | Kyowa Hakko Bio Co., Ltd | microrganismo que produz ácido eicosapentaenoico e método para a produção de ácido eicosapentaenoico |
| CN109777815B (zh) * | 2019-03-28 | 2021-10-29 | 昆明理工大学 | HMG-CoA合成酶基因RKHMGCS及其应用 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE545283A (https=) | ||||
| LU35839A1 (https=) | ||||
| US3223456A (en) * | 1963-11-14 | 1965-12-14 | Siemens Ag | Conveying apparatus for fine-granular material |
| US4381897A (en) * | 1980-10-06 | 1983-05-03 | Krupp Polysius Ag | Installation for transporting fine-grained material |
| US4626505A (en) | 1984-02-24 | 1986-12-02 | E. I. Du Pont De Nemours And Company | Selectable markers for yeast transformation |
| IL83348A (en) * | 1986-08-26 | 1995-12-08 | Du Pont | Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase |
| US5605011A (en) * | 1986-08-26 | 1997-02-25 | E. I. Du Pont De Nemours And Company | Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase |
| US5130242A (en) * | 1988-09-07 | 1992-07-14 | Phycotech, Inc. | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
| US5340742A (en) | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
| US5426040A (en) * | 1989-08-17 | 1995-06-20 | Northeastern University | Methods for producing improved strains of seaweed by fusion of spore-protoplasts, and resultant seaweeds and phycocolloids |
| IL100908A0 (en) | 1991-02-22 | 1992-11-15 | Salk Inst Biotech Ind | Invertase genes and their use |
| US5804408A (en) | 1991-03-13 | 1998-09-08 | Yoshihide Hagiwara | Expression of human SOD in blue green algae |
| US5661017A (en) | 1993-09-14 | 1997-08-26 | Dunahay; Terri Goodman | Method to transform algae, materials therefor, and products produced thereby |
| IL113375A (en) * | 1995-04-13 | 1997-09-30 | Fortress U & T Ltd | Internationally regulated system for one to one cryptographic communications with national sovereignty without key escrow |
| US5853973A (en) * | 1995-04-20 | 1998-12-29 | American Cyanamid Company | Structure based designed herbicide resistant products |
| CA2218526C (en) * | 1995-04-20 | 2012-06-12 | American Cyanamid Company | Structure-based designed herbicide resistant products |
| DE19529475A1 (de) | 1995-08-11 | 1997-02-13 | Marcus Weis | Siebkonstruktion zum Abtrennen des Faseranteils aus der Shredderleichtfraktion |
| US5824309A (en) | 1995-12-05 | 1998-10-20 | University Of Massachusetts | Recombinant gas vesicles and uses thereof |
| WO1997039106A1 (en) | 1996-04-12 | 1997-10-23 | Martek Biosciences Corporation | Methods and tools for transformation of eukaryotic algae |
| US6194167B1 (en) * | 1997-02-18 | 2001-02-27 | Washington State University Research Foundation | ω-3 fatty acid desaturase |
| US5968809A (en) * | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| ES2125195B1 (es) | 1997-04-18 | 1999-10-01 | Antibioticos Sa | Procedimiento de inactivacion de genes que codifican para enzimas del catabolismo del fenilacetato, plasmidos que intervienen y cepas transformadas con los mismos. |
| US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| FR2791699B1 (fr) * | 1999-03-29 | 2004-10-29 | Meristem Therapeutics | Promoteurs chimeriques d'expression, cassettes d'expression, vecteurs, plantes et semences transgeniques les contenant, et methodes de leur obtention |
| KR20000075076A (ko) * | 1999-05-28 | 2000-12-15 | 최태진 | 형질전환된 미세조류를 이용하여 외래 단백질을 생산하는 방법 |
| US7795002B2 (en) | 2000-06-28 | 2010-09-14 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| EP2322644A1 (en) | 2000-06-28 | 2011-05-18 | GlycoFi, Inc. | Methods for producing modified glycoproteins |
| US20060257399A1 (en) | 2000-06-28 | 2006-11-16 | Glycofi, Inc. | Immunoglobulins comprising predominantly a Man5GIcNAc2 glycoform |
| US20060029604A1 (en) | 2000-06-28 | 2006-02-09 | Gerngross Tillman U | Immunoglobulins comprising predominantly a GlcNAc2Man3GlcNAc2 glycoform |
| US7625756B2 (en) | 2000-06-28 | 2009-12-01 | GycoFi, Inc. | Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells |
| EP1911837B1 (en) * | 2000-09-28 | 2011-05-25 | Bioriginal Food & Science Corp. | FAD5-2 fatty acid desaturase family member and uses thereof |
| US6419425B1 (en) * | 2001-02-28 | 2002-07-16 | Neu Transf'air | Granular material distributing apparatus comprising at least two transfer vessels that operate in alternation |
| TWI377253B (en) * | 2001-04-16 | 2012-11-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7332299B2 (en) | 2003-02-20 | 2008-02-19 | Glycofi, Inc. | Endomannosidases in the modification of glycoproteins in eukaryotes |
| ATE404582T1 (de) | 2003-06-05 | 2008-08-15 | Wyeth Corp | Immunogene zusammensetzungen, die replikonvektoren des venezolanischen pferdeencephalitisvirus und paramyxovirus- proteinantigene enthalten |
| JP4796787B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
| JP4796786B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
| PT103331A (pt) | 2005-08-05 | 2007-02-28 | Fundacao Da Faculdade De Cienc | Expressão dum transportador activo de xilose em saccharomyces cerevisiae modificada geneticamente |
| WO2007106905A2 (en) | 2006-03-15 | 2007-09-20 | Martek Biosciences Corporation | Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems |
| CA2659603C (en) | 2006-08-01 | 2017-03-07 | Ocean Nutrition Canada Limited | Oil producing microbes and methods of modification thereof |
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| US20090064567A1 (en) | 2007-09-12 | 2009-03-12 | Martek Biosciences Corporation | Biological oils and production and uses Thereof |
| EP2090648A1 (en) | 2008-02-12 | 2009-08-19 | Institut Francais de Recherche pour l'Exploitation de la Mere(Ifremer) | Production of glycosylated polypeptides in microalgae |
| CN102057048B (zh) | 2008-04-09 | 2015-01-21 | 索拉兹米公司 | 微生物生物质和微生物油的直接化学修饰 |
| EP2519636B8 (en) | 2009-12-28 | 2017-08-09 | DSM IP Assets B.V. | Production of hemagglutinin-neuraminidase protein in microalgae |
| ES2651313T3 (es) | 2009-12-28 | 2018-01-25 | Dsm Ip Assets B.V. | Traustoquítridos recombinantes que crecen en xilosa, y composiciones, métodos de preparación y usos de los mismos |
| IN2012DN06277A (https=) | 2009-12-28 | 2015-09-25 | Dsm Ip Assets Bv | |
| CN103068965A (zh) | 2009-12-28 | 2013-04-24 | Dsmip资产公司 | 在蔗糖上生长的重组破囊壶菌和其组合物、制备方法及用途 |
-
2002
- 2002-04-15 TW TW100112656A patent/TWI377253B/zh not_active IP Right Cessation
- 2002-04-15 TW TW091107634A patent/TWI324181B/zh not_active IP Right Cessation
- 2002-04-15 TW TW098130758A patent/TWI350854B/zh not_active IP Right Cessation
- 2002-04-16 CN CN200910141898A patent/CN101760469A/zh active Pending
- 2002-04-16 AU AU2002250592A patent/AU2002250592C1/en not_active Ceased
- 2002-04-16 EP EP10178886.7A patent/EP2325319B1/en not_active Expired - Lifetime
- 2002-04-16 US US10/124,807 patent/US7001772B2/en not_active Expired - Lifetime
- 2002-04-16 ES ES02719515T patent/ES2377557T3/es not_active Expired - Lifetime
- 2002-04-16 CN CNB2006100842683A patent/CN100513564C/zh not_active Expired - Fee Related
- 2002-04-16 ES ES10178886.7T patent/ES2688953T3/es not_active Expired - Lifetime
- 2002-04-16 EP EP02719515A patent/EP1414941B1/en not_active Expired - Lifetime
- 2002-04-16 ES ES10178911T patent/ES2698473T3/es not_active Expired - Lifetime
- 2002-04-16 CA CA2443908A patent/CA2443908C/en not_active Expired - Fee Related
- 2002-04-16 WO PCT/US2002/012040 patent/WO2002083869A2/en not_active Ceased
- 2002-04-16 JP JP2002582208A patent/JP4536324B2/ja not_active Expired - Fee Related
- 2002-04-16 EP EP10178911.3A patent/EP2314706B1/en not_active Expired - Lifetime
- 2002-04-16 AT AT02719515T patent/ATE533844T1/de active
- 2002-04-16 CN CN028120590A patent/CN1556850B/zh not_active Expired - Fee Related
-
2004
- 2004-12-22 US US11/021,712 patent/US8206984B2/en not_active Expired - Fee Related
-
2007
- 2007-10-27 US US11/925,885 patent/US7851191B2/en not_active Expired - Fee Related
-
2010
- 2010-02-01 JP JP2010019881A patent/JP5248536B2/ja not_active Expired - Lifetime
- 2010-11-09 US US12/942,759 patent/US20110086390A1/en not_active Abandoned
-
2012
- 2012-09-28 JP JP2012215905A patent/JP2013005817A/ja not_active Withdrawn
-
2013
- 2013-06-21 US US13/923,481 patent/US8945875B2/en not_active Expired - Fee Related
-
2015
- 2015-12-25 JP JP2015253726A patent/JP6211577B2/ja not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005503125A5 (https=) | ||
| JP2010508019A5 (https=) | ||
| Lawrence et al. | Selfish operons: horizontal transfer may drive the evolution of gene clusters | |
| US10619190B2 (en) | Compositions, methods, systems and kits for target nucleic acid enrichment | |
| Wada | Growth phase coupled modulation of Escherichia coli ribosomes | |
| JP2009517019A5 (https=) | ||
| JP2002534123A5 (https=) | ||
| JP2011224002A5 (https=) | ||
| EP1390381A2 (en) | Lipid metabolism regulators in plants | |
| JP2021511781A5 (https=) | ||
| JP2019511218A5 (https=) | ||
| JP2010532979A5 (https=) | ||
| CN107075450A (zh) | 在红冬孢酵母属和红酵母属物种中高效产生多不饱和脂肪酸(pufa)的方法 | |
| US20240360404A1 (en) | Expression of functional bacterial type i fatty acid synthase in photosynthetic hosts | |
| WO2011099263A1 (ja) | クルイベロマイセス・マルシアヌス由来の高発現プロモーター | |
| Ye et al. | Efficient genome editing in rice with miniature Cas12f variants | |
| CN104093836A (zh) | 烃合成酶基因及其利用 | |
| CN111850050B (zh) | 一种基因编辑工具及其制备方法与多轮基因编辑的方法 | |
| Schwientek et al. | Improving the genome annotation of the acarbose producer Actinoplanes sp. SE50/110 by sequencing enriched 5′-ends of primary transcripts | |
| JP2007508012A5 (https=) | ||
| CN114480391A (zh) | 用于提高CRISPR/Cas9系统基因编辑效率的启动子及其应用 | |
| JP2008505626A5 (https=) | ||
| US10550409B2 (en) | Drimenol synthases III | |
| CN110366593A (zh) | Dna零件，途径和基因组的进化指导的多重dna装配 | |
| JPS63254985A (ja) | 組換ｄｎａ、発現ベクター及びプラスミド、これらの製法及び誘発可能で抑制可能な外来遺伝子の発現法 |