JP2005501615A5 - - Google Patents

Download PDF

Info

Publication number
JP2005501615A5
JP2005501615A5 JP2003524663A JP2003524663A JP2005501615A5 JP 2005501615 A5 JP2005501615 A5 JP 2005501615A5 JP 2003524663 A JP2003524663 A JP 2003524663A JP 2003524663 A JP2003524663 A JP 2003524663A JP 2005501615 A5 JP2005501615 A5 JP 2005501615A5
Authority
JP
Japan
Prior art keywords
microneedle array
microneedle
microneedles
tip
base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003524663A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005501615A (ja
Filing date
Publication date
Priority claimed from US09/947,195 external-priority patent/US6881203B2/en
Application filed filed Critical
Publication of JP2005501615A publication Critical patent/JP2005501615A/ja
Publication of JP2005501615A5 publication Critical patent/JP2005501615A5/ja
Pending legal-status Critical Current

Links

JP2003524663A 2001-09-05 2002-07-15 マイクロニードルアレイおよびその製造方法 Pending JP2005501615A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/947,195 US6881203B2 (en) 2001-09-05 2001-09-05 Microneedle arrays and methods of manufacturing the same
PCT/US2002/022361 WO2003020359A2 (en) 2001-09-05 2002-07-15 Microneedle arrays and methods of manufacturing the same

Publications (2)

Publication Number Publication Date
JP2005501615A JP2005501615A (ja) 2005-01-20
JP2005501615A5 true JP2005501615A5 (enExample) 2006-01-05

Family

ID=25485700

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003524663A Pending JP2005501615A (ja) 2001-09-05 2002-07-15 マイクロニードルアレイおよびその製造方法

Country Status (8)

Country Link
US (2) US6881203B2 (enExample)
EP (2) EP1425062A2 (enExample)
JP (1) JP2005501615A (enExample)
AT (1) ATE390167T1 (enExample)
DE (1) DE60225859T2 (enExample)
ES (1) ES2304758T3 (enExample)
TW (1) TW550101B (enExample)
WO (1) WO2003020359A2 (enExample)

Families Citing this family (327)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6603987B2 (en) * 2000-07-11 2003-08-05 Bayer Corporation Hollow microneedle patch
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
DE10057832C1 (de) 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
ES2333849T3 (es) * 2001-04-20 2010-03-02 Alza Corporation Disposicion de microsalientes que presenta un revestimiento que contiene un agente beneficioso.
US7537571B2 (en) 2001-06-12 2009-05-26 Pelikan Technologies, Inc. Integrated blood sampling analysis system with multi-use sampling module
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
WO2002100461A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
EP1404233B1 (en) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
CA2448790C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Electric lancet actuator
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
CA2448905C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Blood sampling apparatus and method
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
ES2673480T3 (es) 2002-03-26 2018-06-22 Becton, Dickinson And Company Dispositivo de suministro de fluido por etapas múltiples y método
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7524293B2 (en) 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7481776B2 (en) 2002-04-19 2009-01-27 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
MXPA05000597A (es) * 2002-07-19 2005-04-28 3M Innovative Properties Co Dispositivos de microaguja y aparatos de administracion por microaguja.
WO2004032990A2 (en) 2002-07-22 2004-04-22 Becton, Dickinson And Company Patch-like infusion device
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US7415299B2 (en) * 2003-04-18 2008-08-19 The Regents Of The University Of California Monitoring method and/or apparatus
WO2004107964A2 (en) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Blood harvesting device with electronic control
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
EP1635700B1 (en) 2003-06-13 2016-03-09 Sanofi-Aventis Deutschland GmbH Apparatus for a point of care device
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
BRPI0413538B8 (pt) 2003-08-12 2021-06-22 Becton Dickison And Company dispositivo para fornecer um medicamento para o corpo de um paciente por injeção
CA2536249A1 (en) * 2003-08-25 2005-03-10 3M Innovative Properties Company Delivery of immune response modifier compounds
EP1660172A1 (en) * 2003-08-26 2006-05-31 Alza Corporation Device and method for intradermal cell implantation
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US20090054842A1 (en) * 2003-11-18 2009-02-26 Nanopass Technologies Ltd. Enhanced penetration system and method for sliding microneedles
US7753888B2 (en) * 2003-11-21 2010-07-13 The Regents Of The University Of California Method and/or apparatus for puncturing a surface for extraction, in situ analysis, and/or substance delivery using microneedles
AU2004311977A1 (en) 2003-12-29 2005-07-21 3M Innovative Properties Company Medical devices and kits including same
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
WO2005082593A1 (en) * 2004-02-17 2005-09-09 Avery Dennison Corporation Method of making microneedles
US20070191761A1 (en) * 2004-02-23 2007-08-16 3M Innovative Properties Company Method of molding for microneedle arrays
JP2005246595A (ja) * 2004-03-05 2005-09-15 Ritsumeikan マイクロニードルアレイ及びその製造方法
JP4500851B2 (ja) * 2004-03-12 2010-07-14 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ 横穴付きマイクロ針の製造に使用するための方法および型
US7611481B2 (en) * 2004-03-24 2009-11-03 Corium International, Inc. Transdermal delivery device
AU2005243727B2 (en) * 2004-04-12 2011-04-28 Allergan, Inc. Multi-site injection system
EP1744683B1 (en) 2004-05-13 2016-03-16 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
WO2005123173A1 (en) * 2004-06-10 2005-12-29 3M Innovative Properties Company Patch application device and kit
EP1789127A2 (en) * 2004-08-05 2007-05-30 Apogee Technology, Inc. System and method for drug delivery and microfluidic applications using microneedles
US8696619B2 (en) 2004-08-10 2014-04-15 Robert P. Schnall Drug delivery devices
EP1790375A4 (en) * 2004-08-12 2009-06-17 Hisamitsu Pharmaceutical Co TRANSDERMAL MEDICINE ADMINISTRATION WITH MICRONADEL
ATE490037T1 (de) 2004-08-16 2010-12-15 Functional Microstructures Ltd Verfahren zur herstellung einer mikronadel oder eines mikroimplantats
SE0402100D0 (sv) * 2004-08-30 2004-08-30 Bonsens Ab Molded micro-needles
GB0420256D0 (en) * 2004-09-13 2004-10-13 Cassells John M Method and apparatus for sampling and analysis of fluids
CA2587387C (en) 2004-11-18 2013-06-25 3M Innovative Properties Company Method of contact coating a microneedle array
CN101060882B (zh) 2004-11-18 2010-06-16 3M创新有限公司 微针阵列施放器和保持器
BRPI0517749A (pt) 2004-11-18 2008-10-21 3M Innovative Properties Co dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
CA2588080C (en) * 2004-11-18 2013-01-08 3M Innovative Properties Company Masking method for coating a microneedle array
JP5039559B2 (ja) * 2004-11-26 2012-10-03 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 微細構造製造方法および微細構造製造装置
CA2589733C (en) * 2004-12-07 2014-02-11 3M Innovative Properties Company Method of molding a microneedle
EP1819393B1 (en) * 2004-12-10 2010-10-06 3M Innovative Properties Company Medical device
JP5882556B2 (ja) * 2004-12-28 2016-03-09 ナブテスコ株式会社 皮膚用針、皮膚用針製造装置および皮膚用針製造方法
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
WO2006075689A1 (ja) * 2005-01-14 2006-07-20 Fujikura Ltd. 医薬物運搬用器具とその製造方法
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
EP1869414A4 (en) * 2005-03-29 2010-07-28 Arkal Medical Inc DEVICES, SYSTEMS, METHODS, AND TOOLS FOR CONTINUOUS GLUCOSE MONITORING
JP5301985B2 (ja) 2005-04-07 2013-09-25 スリーエム イノベイティブ プロパティズ カンパニー ツールフィードバック感知のためのシステム及び方法
GB0509863D0 (en) * 2005-05-16 2005-06-22 Cambridge Biostability Ltd Apparatus for administrating substances into a body
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
ATE477833T1 (de) * 2005-06-27 2010-09-15 3M Innovative Properties Co Mikronadelkartuschenanordnung
CA2613111C (en) 2005-06-27 2015-05-26 3M Innovative Properties Company Microneedle array applicator device and method of array application
US20070004989A1 (en) * 2005-06-29 2007-01-04 Parvinder Dhillon Device for transdermal sampling
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
KR20080047600A (ko) * 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
US20070066934A1 (en) * 2005-09-19 2007-03-22 Transport Pharmaceuticals, Inc. Electrokinetic delivery system and methods therefor
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070073212A1 (en) * 2005-09-28 2007-03-29 Takehiko Matsumura Iontophoresis apparatus and method to deliver active agents to biological interfaces
US20070078374A1 (en) * 2005-09-30 2007-04-05 Transcutaneous Technologies Inc. Iontophoretic delivery of vesicle-encapsulated active agents
US7574256B2 (en) * 2005-09-30 2009-08-11 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
JP2009509685A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 損傷組織の治癒を増強するための血管新生因子の送達のためのイオントフォレーシス装置及び方法
JP2009509675A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 新規薬学的ビヒクルを用いる経皮薬剤送達システム、装置、及び方法
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
JP2009509634A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 官能基化マイクロニードル経皮薬剤送達システム、装置及び方法
US20080262416A1 (en) * 2005-11-18 2008-10-23 Duan Daniel C Microneedle Arrays and Methods of Preparing Same
EP1948139A4 (en) * 2005-11-18 2012-04-04 3M Innovative Properties Co COATING COMPOSITIONS, COATINGS DERIVED THEREFROM, AND MICRO-NETWORKS COMPRISING SUCH COATINGS
EP1957145A4 (en) * 2005-11-30 2011-03-23 3M Innovative Properties Co MICRONADEL ASSEMBLIES AND APPLICATION METHOD
CN101330824A (zh) * 2005-12-14 2008-12-24 阿里亚纳控股有限公司 化学制品施用器
US20080319404A1 (en) * 2005-12-21 2008-12-25 Pekurovsky Mikhail L Microneedle Devices
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
WO2007079193A2 (en) * 2005-12-30 2007-07-12 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US20100168501A1 (en) * 2006-10-02 2010-07-01 Daniel Rogers Burnett Method and apparatus for magnetic induction therapy
US9610459B2 (en) * 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US20080306325A1 (en) * 2006-10-02 2008-12-11 Emkinetics Method and apparatus for magnetic induction therapy
JPWO2007091608A1 (ja) * 2006-02-10 2009-07-02 久光製薬株式会社 マイクロニードル付き経皮薬物投与装置
US7699819B2 (en) 2006-02-21 2010-04-20 The Hong Kong University Of Science And Technology Molecular sieve and zeolite microneedles and preparation thereof
GB0605003D0 (en) * 2006-03-13 2006-04-19 Microsample Ltd Method and apparatus for piercing the skin and delivery or collection of liquids
WO2007112309A2 (en) * 2006-03-24 2007-10-04 3M Innovative Properties Company Process for making microneedles, microneedle arrays, masters, and replication tools
US20100049021A1 (en) * 2006-03-28 2010-02-25 Jina Arvind N Devices, systems, methods and tools for continuous analyte monitoring
US20090131778A1 (en) * 2006-03-28 2009-05-21 Jina Arvind N Devices, systems, methods and tools for continuous glucose monitoring
US20080154107A1 (en) * 2006-12-20 2008-06-26 Jina Arvind N Device, systems, methods and tools for continuous glucose monitoring
JP4908893B2 (ja) * 2006-03-30 2012-04-04 久光製薬株式会社 医薬物運搬用器具とその製造方法及び医薬物運搬用器具製造用金型の製造方法
WO2007123707A1 (en) * 2006-03-30 2007-11-01 Tti Ellebeau, Inc. Controlled release membrane and methods of use
CN100441388C (zh) * 2006-04-06 2008-12-10 上海交通大学 基于多层加工技术的微针制备方法
WO2007116959A1 (ja) * 2006-04-07 2007-10-18 Hisamitsu Pharmaceutical Co., Inc. マイクロニードルデバイスおよびマイクロニードル付き経皮薬物投与装置
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
US20070276330A1 (en) * 2006-05-28 2007-11-29 Beck Patricia A Microneedles and methods of fabricating thereof
JP4904964B2 (ja) * 2006-07-24 2012-03-28 凸版印刷株式会社 針状体の製造方法
DE102006036331A1 (de) 2006-08-03 2008-02-14 Stephan Hammelbacher Vorrichtung und Verfahren zum Markieren von Objekten
WO2008020632A1 (en) * 2006-08-18 2008-02-21 Toppan Printing Co., Ltd. Microneedle and microneedle patch
DE102006040642A1 (de) * 2006-08-30 2008-03-13 Robert Bosch Gmbh Mikronadeln zur Platzierung in der Haut zwecks transdermaler Applikation von Pharmazeutika
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
CA2661879A1 (en) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods using inductive power supplies
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
US8062783B2 (en) 2006-12-01 2011-11-22 Tti Ellebeau, Inc. Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices
AU2008209537B2 (en) * 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
US7713196B2 (en) * 2007-03-09 2010-05-11 Nellcor Puritan Bennett Llc Method for evaluating skin hydration and fluid compartmentalization
US20080234562A1 (en) * 2007-03-19 2008-09-25 Jina Arvind N Continuous analyte monitor with multi-point self-calibration
JP5090032B2 (ja) * 2007-03-20 2012-12-05 凸版印刷株式会社 針状体および針状体製造方法
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US20080312518A1 (en) * 2007-06-14 2008-12-18 Arkal Medical, Inc On-demand analyte monitor and method of use
KR101450939B1 (ko) 2007-06-20 2014-10-14 쓰리엠 이노베이티브 프로퍼티즈 컴파니 웨브 상에서의 초음파 사출 성형
JP2009039171A (ja) * 2007-08-06 2009-02-26 Dai Ichi Kasei Kk 微細針形状突起物及びその成形金型及びその製造方法
JP5173332B2 (ja) * 2007-09-10 2013-04-03 凸版印刷株式会社 マイクロニードルおよびマイクロニードル製造方法
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
US20090099427A1 (en) * 2007-10-12 2009-04-16 Arkal Medical, Inc. Microneedle array with diverse needle configurations
US8613721B2 (en) * 2007-11-14 2013-12-24 Medrad, Inc. Delivery and administration of compositions using interventional catheters
WO2009079712A1 (en) 2007-12-24 2009-07-02 The University Of Queensland Coating method
CN102007066B (zh) 2008-02-07 2013-06-26 昆士兰大学 贴片制造
GB0802447D0 (en) * 2008-02-09 2008-03-19 Univ Manchester Fluid extraction device, associated materials and methods
US8398397B2 (en) * 2008-03-12 2013-03-19 Ultradent Products, Inc. Dental intraligamentary injection needles and related methods of manufacture
FR2929135A1 (fr) * 2008-03-31 2009-10-02 Commissariat Energie Atomique Dispositif d'aliquotage et de dispense d'un liquide
WO2009146072A1 (en) 2008-04-01 2009-12-03 The General Hospital Corporation Method and apparatus for tissue expansion
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
USD617463S1 (en) 2008-04-16 2010-06-08 Hisamitsu Pharmaceutical Co., Inc. Combined medical patch and package
USD610690S1 (en) 2008-04-16 2010-02-23 Hisamitsu Pharmaceutical Co., Inc. Combined medical patch and package
CN102105108B (zh) 2008-05-21 2013-12-04 谢拉杰克特股份有限公司 制作固体溶液穿孔器贴剂的方法及其使用
CA2760680A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection by microneedle patch with analyte selective reagents
WO2010016218A1 (ja) * 2008-08-05 2010-02-11 国立大学法人 香川大学 マイクロニードルとその冶具
EP2346414A2 (en) * 2008-09-20 2011-07-27 Steven Craig Anderson Apparatus and method for tissue adhesion
CN105999538A (zh) * 2008-11-18 2016-10-12 3M创新有限公司 空心微针阵列和方法
KR101004014B1 (ko) 2008-12-18 2010-12-31 (주)마이티시스템 측면에 유로가 형성된 미세바늘의 구조 및 그 제작방법
US20110021996A1 (en) * 2008-12-18 2011-01-27 Miti Systems Inc. Structure of micro-needle with side channel and manufacturing method thereof
US8734697B2 (en) 2008-12-22 2014-05-27 The University Of Queensland Patch production
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
AU2010209763B2 (en) 2009-01-30 2016-05-12 Mycartis N.V. Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US20220071534A9 (en) * 2009-03-02 2022-03-10 Yourbio Health, Inc. Delivering and/or receiving fluids
EP2408372B1 (en) 2009-03-02 2019-01-09 Seventh Sense Biosystems, Inc. Devices associated with blood sampling
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
WO2010110397A1 (ja) * 2009-03-25 2010-09-30 国立大学法人 香川大学 マイクロニードルおよびその製造方法と金型
CN101829396B (zh) * 2009-03-27 2013-01-30 清华大学 微针阵列芯片及利用其的经皮给药贴剂及其制备方法
FI20095433A0 (fi) 2009-04-20 2009-04-20 Valtion Teknillinen Mikroneula
CA2759850C (en) * 2009-04-24 2019-10-22 Corium International, Inc. Methods for manufacturing microprojection arrays
US8062568B2 (en) * 2009-08-27 2011-11-22 Korea University Research And Business Foundation Nano pattern writer
AU2010309808B2 (en) 2009-10-21 2016-04-28 Mycartis Nv Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
AU2010313487A1 (en) 2009-10-26 2012-05-24 Emkinetics, Inc. Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues
US20110144591A1 (en) * 2009-12-11 2011-06-16 Ross Russell F Transdermal Delivery Device
WO2011075101A1 (en) 2009-12-16 2011-06-23 Becton, Dickinson And Company Self-injection device
CN102753233B (zh) 2009-12-16 2015-04-01 贝克顿·迪金森公司 自注射装置
JP5894082B2 (ja) 2009-12-16 2016-03-23 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 自己注射装置
JP5650755B2 (ja) 2009-12-16 2015-01-07 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 自己注射装置
WO2011075100A1 (en) 2009-12-16 2011-06-23 Becton, Dickinson And Company Self-injection device
CN102753221B (zh) 2009-12-16 2017-04-26 贝克顿·迪金森公司 自注射装置
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
USD619245S1 (en) 2010-01-08 2010-07-06 Ratio, Inc. Drug delivery device
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
USD638534S1 (en) 2010-01-08 2011-05-24 Ratio, Inc. Drug delivery device
DE102010000843A1 (de) * 2010-01-13 2011-07-14 Robert Bosch GmbH, 70469 Glukose-Sensorvorrichtung mit poröser Mikronadelanordnung, entsprechendes Herstellungsverfahren und Glukose-Messverfahren
EP2924439B1 (en) 2010-03-26 2017-02-01 MyCartis N.V. Ltbp2 as a biomarker for predicting or prognosticating mortality
JP2013524251A (ja) 2010-04-13 2013-06-17 プロノタ エヌ．ヴェ． 妊娠高血圧疾患のバイオマーカー
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
RU2585138C2 (ru) * 2010-04-28 2016-05-27 Кимберли-Кларк Ворлдвайд, Инк. Медицинские устройства для доставки кирнк
US10245421B2 (en) 2010-04-28 2019-04-02 Sorrento Therapeutics, Inc. Nanopatterned medical device with enhanced cellular interaction
CA2796965C (en) 2010-04-28 2019-04-16 Kimberly-Clark Worldwide, Inc. Method for increasing permeability of an epithelial barrier
PT2563450T (pt) * 2010-04-28 2017-08-28 Kimberly Clark Co Dispositivo para entrega de medicação para a artrite reumatóide
US9687641B2 (en) 2010-05-04 2017-06-27 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US9060803B2 (en) 2010-05-07 2015-06-23 The General Hospital Corporation Method and apparatus for tissue grafting and copying
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
AU2011258288B2 (en) 2010-05-28 2015-02-12 Kindeva Drug Delivery L.P. Aqueous formulations for coating microneedle arrays
DE102010030864A1 (de) * 2010-07-02 2012-01-05 Robert Bosch Gmbh Herstellungsverfahren für eine Mikronadelanordnung und entsprechende Mikronadelanordnung und Verwendung
WO2012006677A1 (en) * 2010-07-14 2012-01-19 The University Of Queensland Patch applying apparatus
ES2561824T3 (es) * 2010-07-16 2016-03-01 Seventh Sense Biosystems, Inc. Ambiente a baja presión para dispositivos de transferencia de fluidos
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
CN101912663B (zh) * 2010-08-18 2013-09-04 清华大学 空心微针阵列芯片、经皮给药贴片、器件及制备方法
EP2611478B1 (en) 2010-09-02 2022-08-17 Becton, Dickinson and Company Self-injection device having needle cover with activation preventer
WO2012054518A1 (en) * 2010-10-18 2012-04-26 Lanco Biosciences, Inc. Delivery of copolymers by microinjection systems
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
ES2565805T3 (es) 2010-11-09 2016-04-07 Seventh Sense Biosystems, Inc. Sistemas e interfaces para el muestreo de sangre
ES2580834T3 (es) 2010-12-02 2016-08-29 3M Innovative Properties Company Microagujas de polímero cristalino líquido
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
WO2012122163A1 (en) 2011-03-07 2012-09-13 3M Innovative Properties Company Microneedle devices and methods
US20140066842A1 (en) 2011-03-07 2014-03-06 3M Innovative Properties Company Microneedle devices and methods
EP2686058A1 (en) 2011-03-18 2014-01-22 Université Libre de Bruxelles Devices for puncturing a human or animal body's membrane
KR102237667B1 (ko) 2011-04-29 2021-04-12 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
AU2012249683A1 (en) 2011-04-29 2013-11-14 Seventh Sense Biosystems, Inc. Devices and methods for collection and/or manipulation of blood spots or other bodily fluids
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
US8636696B2 (en) 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
CN103781506B (zh) * 2011-08-05 2016-08-31 尤尼特拉克特注射器私人有限公司 在药物至目标位置的给药中使用的套管及制造套管的方法
CN102319066B (zh) * 2011-08-16 2014-05-07 中国人民解放军广州军区武汉总医院 多通道矩阵式空间叠加心电检测系统
EP2765927B1 (en) * 2011-10-12 2021-02-24 Vaxxas Pty Limited Delivery device
JP6126105B2 (ja) 2011-10-12 2017-05-10 スリーエム イノベイティブ プロパティズ カンパニー 一体化されたマイクロニードル送達システム
CN104039382B (zh) 2011-10-27 2018-01-12 金伯利-克拉克环球有限公司 高粘度生物活性剂的经皮递送
EP3542851B1 (en) 2011-10-27 2021-12-15 Sorrento Therapeutics, Inc. Implantable devices for delivery of bioactive agents
US20170246439A9 (en) * 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
AU2012345768B2 (en) 2011-11-30 2016-05-12 Kindeva Drug Delivery L.P. Microneedle device having a peptide therapeutic agent and an amino acid, methods of making and using the same
HK1209658A1 (en) 2012-05-01 2016-04-08 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
US10980865B2 (en) 2012-08-10 2021-04-20 Aquavit Pharmaceuticals, Inc. Direct application system and method for the delivery of bioactive compositions and formulations
EP4501260A3 (en) 2012-08-14 2025-03-19 The General Hospital Corporation Apparatus for tissue harvesting
KR102216949B1 (ko) 2012-12-14 2021-02-22 민데라 코포레이션 바이오마커의 검출 및 취득을 위한 방법 및 디바이스
JP6865524B2 (ja) 2012-12-21 2021-04-28 コリウム， インコーポレイテッド 治療剤を送達するためのマイクロアレイおよび使用方法
EP2938390A1 (en) 2012-12-27 2015-11-04 3M Innovative Properties Company Article with hollow microneedles and method of making
CN105025976B (zh) * 2013-01-21 2019-01-08 白雁美学公司 微型针、微型针的制造模具和制造方法
EP2958533B8 (en) 2013-02-20 2022-02-16 Cytrellis Biosystems, Inc. Methods and devices for skin tightening
JP6487899B2 (ja) 2013-03-12 2019-03-20 コリウム インターナショナル， インコーポレイテッド 微小突起アプリケータ
EP2968118B1 (en) 2013-03-15 2022-02-09 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
WO2014144973A1 (en) 2013-03-15 2014-09-18 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
BR112016002695B1 (pt) 2013-08-09 2022-09-20 Cytrellis Biosystems, Inc Dispositivo com um aparelho ablativo, um aparelho de remoção e um aparelho de posicionamento
DE102013219432A1 (de) * 2013-09-26 2015-03-26 Peter Röhr Blutentnahmevorrichtung und Verfahren zum Entnehmen von Blut
EP3082897A4 (en) 2013-12-19 2017-07-26 Cytrellis Biosystems, Inc. Methods and devices for manipulating subdermal fat
US20150174386A1 (en) * 2013-12-19 2015-06-25 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
US10994112B2 (en) * 2014-02-05 2021-05-04 Amgen Inc. Drug delivery system with electromagnetic field generator
PT3122426T (pt) 2014-03-28 2023-02-28 Univ Duke Tratamento de cancro da mama utilizando moduladores seletivos do recetor de estrogénio
WO2015164840A1 (en) * 2014-04-24 2015-10-29 Georgia Tech Research Corporation Microneedles and methods of manufacture thereof
US11065027B2 (en) 2014-07-15 2021-07-20 The General Hospital Corporation Method and apparatus for tissue copying and grafting
WO2016033652A1 (en) * 2014-09-03 2016-03-10 Newsouth Innovations Pty Limited Microfluidic devices and fabrication
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
CA2967636A1 (en) 2014-11-14 2016-05-19 Cytrellis Biosystems, Inc. Devices and methods for ablation of the skin
EP4218892A1 (en) 2015-02-02 2023-08-02 Vaxxas Pty Limited Microprojection array applicator
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
JP2016195651A (ja) * 2015-04-02 2016-11-24 日本写真印刷株式会社 マイクロニードルシート
US9743949B2 (en) 2015-04-22 2017-08-29 Medline Industries, Inc. Two-dimensional needle array device and method of use
EP3288383A4 (en) 2015-04-29 2019-01-23 Radius Pharmaceuticals, Inc. METHOD FOR THE TREATMENT OF CANCER
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
AU2016333148B2 (en) 2015-09-28 2021-10-14 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
JP6499598B2 (ja) 2015-10-06 2019-04-10 富士フイルム株式会社 経皮吸収シートの製造方法
US10695289B2 (en) 2015-10-09 2020-06-30 3M Innovative Properties Company Zinc compositions for coated microneedle arrays
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
KR101811513B1 (ko) 2015-11-25 2017-12-20 주식회사 파이안에스테틱스 마이크로 스피큘과 이의 제조용 몰드 및 이의 제조방법
CA3007291C (en) 2015-12-04 2019-10-22 Ascilion Ab A microneedle and a chip
US10987502B2 (en) * 2015-12-15 2021-04-27 Hisamitsu Pharmaceutical Co., Inc. Microneedle sheet
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
JP2019513070A (ja) 2016-03-01 2019-05-23 キトテック メディカル， インコーポレイテッド 創傷閉鎖のための微細構造に基づくシステム、装置および方法
WO2017172920A1 (en) 2016-03-29 2017-10-05 Cytrellis Biosystems, Inc. Devices and methods for cosmetic skin resurfacing
JP2017176652A (ja) * 2016-03-31 2017-10-05 花王株式会社 微細中空突起具
AU2017253674B2 (en) 2016-04-18 2021-07-29 Kindeva Drug Delivery L.P. Formulations of abaloparatide, transdermal patches thereof, and uses thereof
JP2019529043A (ja) 2016-09-21 2019-10-17 サイトレリス バイオシステムズ，インコーポレーテッド 美容スキンリサーフェシング装置及び方法
US12415058B2 (en) 2016-12-22 2025-09-16 Ohio State Innovation Foundation Interpenetrating microstructures for nanochannel-based sampling and/or cargo delivery
WO2018119090A1 (en) * 2016-12-22 2018-06-28 Ohio State Innovation Foundation Interpentrating microstructures for nanochannel-based cargo delivery
ES2981967T3 (es) 2017-01-05 2024-10-14 Radius Pharmaceuticals Inc Formas polimórficas de RAD1901-2HCl
WO2018132430A1 (en) 2017-01-10 2018-07-19 A.T. Still Universiy Fluid infusion system
CN115923337A (zh) 2017-03-31 2023-04-07 瓦克萨斯私人有限公司 用于涂覆表面的设备和方法
WO2018227246A1 (en) 2017-06-13 2018-12-20 Vaxxas Pty Limited Quality control of substrate coatings
JP1601442S (enExample) * 2017-07-28 2018-04-09
US11464957B2 (en) 2017-08-04 2022-10-11 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP)
WO2019033361A1 (zh) * 2017-08-17 2019-02-21 深圳华迈兴微医疗科技有限公司 一种采血装置及其控制设备
KR20220124281A (ko) * 2017-10-16 2022-09-13 트러스티즈 오브 터프츠 칼리지 마이크로니들 제조 시스템 및 방법
CN108744258B (zh) * 2018-05-04 2024-03-08 陈彦彪 一种蜂刺疗法用微针设备及其制备方法
US11318292B2 (en) 2018-05-28 2022-05-03 Microneedles Inc. Microneedle patch for transdermal injections
JP7473486B2 (ja) 2018-07-04 2024-04-23 ラジウス ファーマシューティカルズ，インコーポレイテッド Ｒａｄ１９０１－２ｈｃｌの多形形態
US20210322746A1 (en) * 2018-08-28 2021-10-21 Nissha Co., Ltd. Skin quality-improving sheet
JP2020078363A (ja) * 2018-11-10 2020-05-28 コスメディ製薬株式会社 マイクロニードルアレイの製造方法
JOP20210218A1 (ar) 2019-02-12 2023-01-30 Radius Pharmaceuticals Inc عمليات ومركبات
WO2020232394A1 (en) 2019-05-16 2020-11-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Microneedle arrays with undercut features for cutaneous and non-cutaneous drug delivery
EP3795358A1 (de) * 2019-09-20 2021-03-24 Axenoll Life Sciences AG Mikronadel und verfahren zur herstellung einer mikronadel
WO2021168345A1 (en) 2020-02-19 2021-08-26 Kitotech Medical, Inc. Microstructure systems and methods for pain treatment
CN115734798A (zh) 2020-04-28 2023-03-03 提克纳有限责任公司 微针组件
CN112618945B (zh) * 2020-12-14 2022-06-21 北京航空航天大学 中空封闭型微针及其制备方法和包括该微针的操作装置
CN113712547B (zh) * 2021-09-07 2023-12-29 集美大学 多槽微针阵列及其制备方法、生物检测微针传感器
CN114209975B (zh) * 2021-12-14 2022-07-26 优微（珠海）生物科技有限公司 一种基底易撕微针贴
CN218685709U (zh) * 2021-12-23 2023-03-24 苏州纳生微电子有限公司 微针阵列芯片
WO2023159181A1 (en) 2022-02-18 2023-08-24 Kitotech Medical, Inc. Force modulating deep skin staples and instruments
TWI856848B (zh) * 2023-10-19 2024-09-21 達運精密工業股份有限公司 微針裝置

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4018938A (en) 1975-06-30 1977-04-19 International Business Machines Corporation Fabrication of high aspect ratio masks
US4165395A (en) 1977-06-30 1979-08-21 International Business Machines Corporation Process for forming a high aspect ratio structure by successive exposures with electron beam and actinic radiation
JPS5590931A (en) 1978-12-29 1980-07-10 Canon Inc Production of micro structure element array
US4568632A (en) 1982-10-07 1986-02-04 International Business Machines Corporation Patterning of polyimide films with far ultraviolet light
FR2535602B1 (fr) * 1982-11-05 1986-06-13 Stallergenes Lab Dispositif scarificateur
US4508749A (en) 1983-12-27 1985-04-02 International Business Machines Corporation Patterning of polyimide films with ultraviolet light
US4822975A (en) 1984-01-30 1989-04-18 Canon Kabushiki Kaisha Method and apparatus for scanning exposure
DE3517729A1 (de) 1985-05-17 1986-11-20 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe Verfahren zum herstellen von spinnduesenplatten
US4768358A (en) 1986-08-04 1988-09-06 Robert Viola Security handle lock
JPH01245993A (ja) 1988-03-27 1989-10-02 Semiconductor Energy Lab Co Ltd 薄膜加工装置
GB2221394B (en) 1988-08-05 1992-03-04 Eilert Eilertsen An injection device
DE3842354A1 (de) 1988-12-16 1990-06-21 Kernforschungsz Karlsruhe Verfahren zur lithographischen herstellung von galvanisch abformbaren mikrostrukturen mit dreieckigem oder trapezfoermigem querschnitt
DE3842610C1 (enExample) 1988-12-17 1990-06-21 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe, De
CA2016900A1 (en) * 1989-07-06 1991-01-06 Ronald J. Filipski Tines structure in clinical applicator
US5697901A (en) * 1989-12-14 1997-12-16 Elof Eriksson Gene delivery by microneedle injection
DE4010669C1 (enExample) 1990-04-03 1991-04-11 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe, De
US5389954A (en) 1990-11-21 1995-02-14 Canon Kabushiki Kaisha Laser process apparatus for forming holes in a workpiece
US5160823A (en) 1991-01-03 1992-11-03 Hutchinson Technology, Inc. Moving mask laser imaging
DE4222856C1 (enExample) 1992-07-11 1993-05-27 Buerkert Gmbh
JP3211525B2 (ja) 1993-04-22 2001-09-25 オムロン株式会社 薄材メッシュ、その製造方法及びその製造装置
EP0783727A4 (en) 1994-09-09 1998-01-14 Univ Louisiana State MICROSTRUCTURES AND METHOD FOR MANUFACTURING MICROSTRUCTURES
WO1996033839A1 (en) 1995-04-26 1996-10-31 Minnesota Mining And Manufacturing Company Method and apparatus for step and repeat exposures
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
DE69719761T2 (de) * 1996-06-18 2003-12-18 Alza Corp., Palo Alto Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
CA2259437C (en) * 1996-07-03 2006-12-05 Altea Technologies, Inc. Multiple mechanical microporation of skin or mucosa
WO1999064580A1 (en) 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
GB9815820D0 (en) 1998-07-22 1998-09-16 Secr Defence Improvements relating to micro-machining
GB9817662D0 (en) * 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
AU2189400A (en) * 1998-12-18 2000-07-03 Minimed, Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same
AU5461300A (en) 1999-06-04 2000-12-28 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US6331266B1 (en) 1999-09-29 2001-12-18 Becton Dickinson And Company Process of making a molded device
CN1390148A (zh) * 1999-11-15 2003-01-08 维尔克鲁工业公司 皮肤附着件
US6558361B1 (en) * 2000-03-09 2003-05-06 Nanopass Ltd. Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
US6565532B1 (en) * 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
JP2002079499A (ja) * 2000-09-08 2002-03-19 Terumo Corp 針形状物の作製方法および作製された針
US6855131B2 (en) * 2000-10-13 2005-02-15 Alza Corporation Microprotrusion member retainer for impact applicator
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography

Similar Documents

Publication Publication Date Title
JP2005501615A5 (enExample)
JP5718312B2 (ja) 流体伝達を調節することができるマイクロニードルユニット
ATE384549T1 (de) Mikronadel-vorrichtungen und verfahren zur herstellung
EP2906284B1 (en) Force-controlled applicator for applying a microneedle device to skin
JP5587946B2 (ja) 目立たないマイクロニードルアレイアプリケーター
BR0312671A (pt) Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas
JP5049268B2 (ja) マイクロニードルデバイスおよびマイクロニードル付き経皮薬物投与装置
WO2002085446A3 (en) Microprojection array immunization patch and method
NO20031681L (no) Anordning og fremgangsmåte for gjennomhulling av hud med mikrofremspring
WO2006116281A3 (en) Method of treating acne with stratum corneum piercing device
WO2006110773A3 (en) Ultrasound catheter with cavitation promoting surface
CA2456626A1 (en) Microstructures for delivering a composition cutaneously to skin using rotatable structures
WO2004060447A3 (en) Transdermal delivery using encapsulated agent activated by ultrasound and/or heat
WO2006022933A3 (en) System and method for drug delivery and microfluidic applications using microneedles
WO2008028087A3 (en) Methods and apparatus incorporating a surface penetration device
WO2004105729A3 (en) Transdermal vaccine delivery device having coated microprotrusions
CA2422909A1 (en) Microstructures for delivering a composition cutaneously to skin
WO2005002662A3 (en) Percutaneous electrode array
WO2005099751A3 (en) Apparatus and method for transdermal delivery of influenza vaccine
US20140114234A1 (en) Systems and Methods for Enhancing the Delivery of Compounds to Skin Pores using Ultrasonic Waveforms
WO2005051455A3 (en) Ultrasound assisted transdermal vaccine delivery method and system
WO2004064610A3 (en) Microdermabrasion devices, compositions, and methods
JP2007509705A5 (enExample)
MXPA03003815A (es) Dispositivos de suministro transdermico de farmaco que tienen microrresaltos recubiertos.
JP2015100659A (ja) マイクロニードルシートの製造方法