|
JPH0250488A
(ja)
*
|
1988-08-11 |
1990-02-20 |
Nec Corp |
超伝導配線
|
|
BRPI0111830B8
(pt)
*
|
2000-06-23 |
2021-05-25 |
American Cyanamid Co |
método de produção de partículas semelhantes ao vírus da influenza (vlps), vlps da influenza, vlps quiméricas, composições imunogênica e farmacêutica, e, usos de vlps da influenza e de vlps quiméricas
|
|
US9045727B2
(en)
|
2002-05-17 |
2015-06-02 |
Emory University |
Virus-like particles, methods of preparation, and immunogenic compositions
|
|
US20060088909A1
(en)
*
|
2002-05-17 |
2006-04-27 |
Compans Richard W |
Virus-like particles, methods of preparation, and immunogenic compositions
|
|
US20060121468A1
(en)
*
|
2002-06-26 |
2006-06-08 |
Allnutt F C T |
Viruses and virus-like particles for multiple antigen and target display
|
|
ES2217967B1
(es)
*
|
2003-03-31 |
2006-01-01 |
Consejo Sup. Investig. Cientificas |
Procedimiento de produccion de particulas virales vacias (vlps) del virus inductor de la bursitis infecciosa (ibdv), composiciones necesarias para su puesta a punto y su uso en la elaboracion de vacunas frente al ibdv.
|
|
BRPI0410562B8
(pt)
|
2003-05-22 |
2021-05-25 |
Fralunhofer Usa Inc |
proteína de veículo e seu método de produção em uma planta, ácido nucleico isolado, vetor de expressão e célula hospedeira
|
|
US8551756B2
(en)
*
|
2003-07-11 |
2013-10-08 |
Novavax, Inc. |
Avian influenza chimeric VLPS
|
|
AU2011218606B2
(en)
*
|
2003-07-11 |
2012-01-12 |
Novavax, Inc |
Functional influenza virus-like particles (VLPS)
|
|
US8506967B2
(en)
|
2003-07-11 |
2013-08-13 |
Novavax, Inc. |
Functional influenza virus like particles (VLPs)
|
|
US8080255B2
(en)
|
2003-07-11 |
2011-12-20 |
Novavax Inc. |
Functional influenza virus like particles (VLPs)
|
|
US8992939B2
(en)
|
2003-07-11 |
2015-03-31 |
Novavax, Inc. |
Highly efficient influenza matrix (M1) proteins
|
|
US8592197B2
(en)
|
2003-07-11 |
2013-11-26 |
Novavax, Inc. |
Functional influenza virus-like particles (VLPs)
|
|
ES2307345B1
(es)
*
|
2004-01-21 |
2009-11-13 |
Consejo Sup. Investig. Cientificas |
Capsidas vacias quimericas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones.
|
|
ES2307346B1
(es)
*
|
2004-01-21 |
2009-11-13 |
Consejo Sup. Investig. Cientificas |
Capsidas vacias (vlps(-vp4)) del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones.
|
|
JP4896021B2
(ja)
*
|
2004-05-21 |
2012-03-14 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド |
呼吸器系病原体ワクチンのためのアルファウイルスベクター
|
|
MX2007010008A
(es)
*
|
2005-02-16 |
2008-01-18 |
Lentigen Corp |
Vectores lentivirales y su uso.
|
|
ES2310062B1
(es)
|
2005-07-15 |
2009-11-13 |
Bionostra, S.L. |
Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones.
|
|
CA2616859C
(en)
|
2005-08-03 |
2015-04-14 |
Fraunhofer Usa, Inc. |
Compositions and methods for production of immunoglobulins
|
|
TWI488968B
(zh)
*
|
2005-10-18 |
2015-06-21 |
Novavax Inc |
功能性流行性感冒類病毒顆粒（ＶＬＰｓ）
|
|
EP2251034B1
(en)
|
2005-12-02 |
2018-02-14 |
Icahn School of Medicine at Mount Sinai |
Chimeric newcastle disease viruses presenting non-native surface proteins and uses thereof
|
|
ES2385842T3
(es)
*
|
2005-12-06 |
2012-08-01 |
Yeda Research And Development Co., Ltd. |
Vacuna mejorada contra la gripe
|
|
CA2638815A1
(en)
*
|
2006-02-02 |
2007-08-16 |
Globeimmune, Inc. |
Yeast-based vaccine for inducing an immune response
|
|
JP2009526526A
(ja)
*
|
2006-02-13 |
2009-07-23 |
フラウンホーファー ユーエスエー， インコーポレイテッド |
インフルエンザ抗原、ワクチン組成物、および関連する方法
|
|
WO2008048344A2
(en)
*
|
2006-02-13 |
2008-04-24 |
Fraunhofer Usa, Inc. |
Bacillus anthracis antigens, vaccine compositions, and related methods
|
|
KR20080106434A
(ko)
*
|
2006-02-13 |
2008-12-05 |
프라운호퍼 유에스에이, 인코포레이티드 |
Ｈｐｖ 항원, 백신 조성물 및 관련된 방법
|
|
EP3011969A1
(en)
*
|
2006-03-07 |
2016-04-27 |
Vaxinnate Corporation |
Compositions that include hemagglutinin, methods of making and methods of use thereof
|
|
WO2007126788A2
(en)
*
|
2006-03-27 |
2007-11-08 |
Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods and compositions for the treatment and prevention of viral infection
|
|
US7682619B2
(en)
|
2006-04-06 |
2010-03-23 |
Cornell Research Foundation, Inc. |
Canine influenza virus
|
|
WO2007130327A2
(en)
*
|
2006-05-01 |
2007-11-15 |
Technovax, Inc. |
Influenza virus-like particle (vlp) compositions
|
|
WO2007130330A2
(en)
*
|
2006-05-01 |
2007-11-15 |
Technovax, Inc. |
Polyvalent influenza virus-like particle (vlp) compositions
|
|
KR100702034B1
(ko)
*
|
2006-05-12 |
2007-03-30 |
삼성전자주식회사 |
반도체 장치, 이 장치의 전원 노이즈 감소 방법 및 인쇄회로 기판
|
|
US8153115B2
(en)
|
2006-06-15 |
2012-04-10 |
Ben-Gurion University Of The Negev Research And Development Authority |
Virus-like particles for treatment of viral infections
|
|
JP2009543554A
(ja)
|
2006-07-14 |
2009-12-10 |
サノフィ パスツール バイオロジクス カンパニー |
ベクターウイルスタンパク質への外来免疫決定基の直接トランスポゾン媒介挿入による組換え型ウイルスワクチンの構築
|
|
EP2044198A4
(en)
*
|
2006-07-27 |
2010-09-08 |
Ligocyte Pharmaceuticals Inc |
CHIMERIC INFLUENZA VIRUS TYPE PARTICLES
|
|
EP2044224A4
(en)
*
|
2006-07-27 |
2011-04-13 |
Ligocyte Pharmaceuticals Inc |
CHIMERIC VIRUS TYPE PARTICLES
|
|
CA2664791A1
(en)
|
2006-09-29 |
2008-08-21 |
Sanofi Pasteur Biologics Co. |
Recombinant rhinovirus vectors
|
|
CA2669485C
(en)
*
|
2006-11-15 |
2017-01-03 |
Folia Biotech Inc. |
Papaya mosaic virus-based vaccines for influenza
|
|
CN101553252A
(zh)
*
|
2006-12-06 |
2009-10-07 |
诺华有限公司 |
包含来自于四株流感病毒的抗原的疫苗
|
|
US7998487B2
(en)
*
|
2007-02-16 |
2011-08-16 |
The Salk Institute For Biological Studies |
Antitoxin and vaccine platform based on nodavirus VLPs
|
|
BRPI0810865A2
(pt)
*
|
2007-04-28 |
2017-05-09 |
Fraunhofer Usa Inc |
antígenos de tripanossoma, composições vacinais, e métodos relacionados
|
|
WO2008148104A1
(en)
|
2007-05-25 |
2008-12-04 |
Novavax, Inc. |
Novel vlps derived from cells that do not express a viral matrix or core protein
|
|
WO2009009759A2
(en)
|
2007-07-11 |
2009-01-15 |
Fraunhofer Usa, Inc. |
Yersinia pestis antigens, vaccine compositions, and related methods
|
|
MX2010001284A
(es)
|
2007-08-02 |
2010-08-31 |
Biondvax Pharmaceuticals Ltd |
Vacunas contra la influenza con multiepitope multimerico.
|
|
BRPI0815662A2
(pt)
*
|
2007-08-20 |
2016-09-27 |
Fraunhofer Usa Inc |
vacinas, antígenos, composições, e métodos profilácticos e terapêuticos para gripe
|
|
EA034733B1
(ru)
*
|
2008-01-21 |
2020-03-13 |
Медикаго Инк. |
Нуклеиновая кислота для увеличенной экспрессии гемагглютинина вируса гриппа в растении и ее применение
|
|
WO2009128952A2
(en)
|
2008-04-18 |
2009-10-22 |
Vaxinnate Corporation |
Compositions of papillomavirus proteins and methods of use
|
|
WO2010012069A1
(en)
*
|
2008-07-30 |
2010-02-04 |
Folio Biotech Inc. |
Multivalent vaccines based on papaya mosaic virus and uses thereof
|
|
US8734803B2
(en)
|
2008-09-28 |
2014-05-27 |
Ibio Inc. |
Humanized neuraminidase antibody and methods of use thereof
|
|
EP2396032B1
(en)
|
2009-02-10 |
2016-09-28 |
Seqirus UK Limited |
Influenza vaccines with reduced amounts of squalene
|
|
CN102414313B
(zh)
*
|
2009-05-01 |
2014-04-02 |
雷德生物科技股份公司 |
多基因载体编码的重组病毒样颗粒
|
|
EP2427547A1
(en)
*
|
2009-05-08 |
2012-03-14 |
GlaxoSmithKline Biologicals S.A. |
Method for producing virus from cell culture involving homogenization
|
|
PL222497B1
(pl)
*
|
2009-06-26 |
2016-08-31 |
Inst Biochemii I Biofizyki Pan |
Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania, kompozycja farmaceutyczna oraz zastosowanie wektorowej cząsteczki wirusopodobnej
|
|
WO2011003100A2
(en)
|
2009-07-02 |
2011-01-06 |
Massachusetts Institute Of Technology |
Compositions and methods for diagnosing and/or treating influenza infection
|
|
US8784819B2
(en)
|
2009-09-29 |
2014-07-22 |
Ibio Inc. |
Influenza hemagglutinin antibodies, compositions and related methods
|
|
WO2011046925A1
(en)
*
|
2009-10-12 |
2011-04-21 |
Technovax, Inc. |
Respiratory syncytial virus (rsv) virus-like particles (vlps)
|
|
CN102753582A
(zh)
|
2009-11-03 |
2012-10-24 |
莱戈赛特医药股份有限公司 |
嵌合RSV-F多肽、和慢病毒或α-反转录病毒GAG基VLP
|
|
EP3505632B1
(en)
*
|
2009-12-28 |
2022-08-03 |
Sanofi Vaccine Technologies, S.A.S. |
Production of heterologous polypeptides in microalgae, microalgal extracellular bodies, compositions, and methods of making and uses thereof
|
|
US20130028933A1
(en)
*
|
2009-12-28 |
2013-01-31 |
Ligocyte Pharmaceuticals, Inc. |
Methods for stabilizing influenza antigen enveloped virus-based virus-like particle solutions
|
|
WO2011102900A1
(en)
*
|
2010-02-18 |
2011-08-25 |
Technovax, Inc. |
Universal virus-like particle (vlp) influenza vaccines
|
|
CN102373182A
(zh)
*
|
2010-08-09 |
2012-03-14 |
中山大学 |
禽流感和传染性囊病混合病毒样颗粒、制备方法和应用
|
|
CN102373184A
(zh)
*
|
2010-08-09 |
2012-03-14 |
中山大学 |
禽流感和传染性支气管炎混合病毒样颗粒、制备方法和应用
|
|
CN102370976B
(zh)
*
|
2010-08-09 |
2014-06-11 |
中山大学 |
猪流感病毒和猪口蹄疫病毒的混合病毒样颗粒、制备方法和应用
|
|
CN102373181B
(zh)
*
|
2010-08-09 |
2014-06-11 |
中山大学 |
猪流感病毒和猪蓝耳病病毒混合病毒样颗粒、制备方法和应用
|
|
CN102373183A
(zh)
*
|
2010-08-09 |
2012-03-14 |
中山大学 |
禽流感和新城疫混合病毒样颗粒、制备方法和应用
|
|
EP2640405A4
(en)
|
2010-09-21 |
2015-04-15 |
Massachusetts Inst Technology |
HA-POLYPEPTIDES ADAPTED TO HUMANS, VACCINES THEREOF AND INFLUENZA TREATMENT THEREWITH
|
|
SG10201709806VA
(en)
|
2010-10-04 |
2017-12-28 |
Massachusetts Inst Technology |
Hemagglutinin polypeptides, and reagents and methods relating thereto
|
|
US9821051B1
(en)
|
2010-10-28 |
2017-11-21 |
Seqirus UK Limited |
Reducing hospitalization in elderly influenza vaccine recipients
|
|
AU2011360572B2
(en)
|
2011-02-22 |
2017-03-02 |
Biondvax Pharmaceuticals Ltd. |
Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines
|
|
JP6113155B2
(ja)
|
2011-06-20 |
2017-04-12 |
ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション |
計算で最適化した広い反応性を示すｈ１ｎ１インフルエンザの抗原
|
|
EP3275464A1
(en)
*
|
2011-08-01 |
2018-01-31 |
Emory University |
Vlps containing ligands and methods related thereto
|
|
KR20140068205A
(ko)
*
|
2011-09-20 |
2014-06-05 |
마운트 시나이 스쿨 오브 메디슨 |
인플루엔자 바이러스 백신 및 이의 용도
|
|
BR112014019755B1
(pt)
|
2012-03-22 |
2022-02-22 |
Fraunhofer Usa, Inc |
Partícula do tipo viral; método de produção das partículas do tipo viral; composição imunogênica e uso das partículas do tipo viral
|
|
EP2831094B1
(en)
|
2012-03-30 |
2018-06-13 |
University of Pittsburgh - Of the Commonwealth System of Higher Education |
Computationally optimized broadly reactive antigens for h5n1 and h1n1 influenza viruses
|
|
TWI434933B
(zh)
*
|
2012-04-17 |
2014-04-21 |
Nat Univ Tsing Hua |
抗多型禽流感病毒之ｄｎａ疫苗及其組合物
|
|
US8932598B2
(en)
|
2012-08-28 |
2015-01-13 |
Vaxinnate Corporation |
Fusion proteins and methods of use
|
|
JP2016505538A
(ja)
|
2012-11-27 |
2016-02-25 |
ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション |
Ｈ１ｎ１インフルエンザに対する計算で最適化した広い反応性を示す抗原
|
|
KR20150104117A
(ko)
|
2012-12-18 |
2015-09-14 |
이칸 스쿨 오브 메디슨 엣 마운트 시나이 |
인플루엔자 바이러스 백신 및 그의 용도
|
|
WO2014159960A1
(en)
|
2013-03-14 |
2014-10-02 |
Icahn School Of Medicine At Mount Sinai |
Antibodies against influenza virus hemagglutinin and uses thereof
|
|
US9322037B2
(en)
|
2013-09-06 |
2016-04-26 |
President And Fellows Of Harvard College |
Cas9-FokI fusion proteins and uses thereof
|
|
US9340800B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
Extended DNA-sensing GRNAS
|
|
US10080792B2
(en)
|
2013-09-23 |
2018-09-25 |
Engen Bio, Inc. |
Influenza vaccine and therapy
|
|
CN104436157A
(zh)
|
2013-09-23 |
2015-03-25 |
恩金生物有限公司 |
流感疫苗和治疗
|
|
US10736956B2
(en)
|
2015-01-23 |
2020-08-11 |
Icahn School Of Medicine At Mount Sinai |
Influenza virus vaccination regimens
|
|
KR101729387B1
(ko)
|
2015-04-17 |
2017-04-21 |
경희대학교 산학협력단 |
곤충세포 발현시스템을 이용한 인플루엔자 백신 소재 ｍ1-ｍ2-ｎａ-ｈａ 바이러스 유사 입자의 제조방법
|
|
MX2018002728A
(es)
|
2015-09-03 |
2018-09-05 |
Novavax Inc |
Composiciones de vacuna que tienen estabilidad e inmunogenicidad mejoradas.
|
|
US10391163B2
(en)
*
|
2015-09-10 |
2019-08-27 |
Academia Sinica |
Bird flu vaccine combination comprising virus-like particles and novel adjuvants
|
|
WO2017218624A1
(en)
|
2016-06-15 |
2017-12-21 |
Icahn School Of Medicine At Mount Sinai |
Influenza virus hemagglutinin proteins and uses thereof
|
|
CA3046778A1
(en)
*
|
2016-10-31 |
2018-05-03 |
Georgia State University Research Foundation, Inc. |
A virus like particle of hepatitis b virus pre-s protein
|
|
US11898179B2
(en)
|
2017-03-09 |
2024-02-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
|
CN110662556A
(zh)
|
2017-03-09 |
2020-01-07 |
哈佛大学的校长及成员们 |
癌症疫苗
|
|
WO2018187706A2
(en)
|
2017-04-07 |
2018-10-11 |
Icahn School Of Medicine At Mount Sinai |
Anti-influenza b virus neuraminidase antibodies and uses thereof
|
|
US11732274B2
(en)
|
2017-07-28 |
2023-08-22 |
President And Fellows Of Harvard College |
Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)
|
|
EP3810634A4
(en)
|
2018-06-21 |
2022-07-27 |
Icahn School of Medicine at Mount Sinai |
Mosaic influenza virus hemagglutinin polypeptides and uses thereof
|
|
US12522807B2
(en)
|
2018-07-09 |
2026-01-13 |
The Broad Institute, Inc. |
RNA programmable epigenetic RNA modifiers and uses thereof
|
|
CN111315407B
(zh)
|
2018-09-11 |
2023-05-02 |
上海市公共卫生临床中心 |
一种广谱抗流感疫苗免疫原及其应用
|
|
MX2019014943A
(es)
|
2018-12-12 |
2020-08-06 |
Cambridge Tech Llc |
Vacuna universal contra la gripe.
|
|
WO2020154500A1
(en)
|
2019-01-23 |
2020-07-30 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
MX2021011426A
(es)
|
2019-03-19 |
2022-03-11 |
Broad Inst Inc |
Metodos y composiciones para editar secuencias de nucleótidos.
|
|
WO2020214842A1
(en)
|
2019-04-17 |
2020-10-22 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
EP3959216A4
(en)
|
2019-04-24 |
2023-01-11 |
Icahn School of Medicine at Mount Sinai |
ANTI-INFLUENZA B VIRUS NEURAMINIDASE ANTIBODIES AND USES THEREOF
|
|
CN114258398A
(zh)
|
2019-06-13 |
2022-03-29 |
总医院公司 |
工程化的人内源性病毒样颗粒及使用其递送至细胞的方法
|
|
BR112023001272A2
(pt)
|
2020-07-24 |
2023-04-04 |
Massachusetts Gen Hospital |
Partículas semelhantes a vírus aprimoradas e métodos de uso das mesmas para entrega às células
|
|
CN116063409A
(zh)
*
|
2022-09-09 |
2023-05-05 |
中山大学·深圳 |
一种乙型流感Mosaic重组蛋白、重组质粒及其构建方法和应用
|