CY1107835T1 - Συναθροιση αγριου-τυπου και χιμαιρικων σωματιδιων που ομοιαζουν με ιο γριπης (vlps) - Google Patents

Συναθροιση αγριου-τυπου και χιμαιρικων σωματιδιων που ομοιαζουν με ιο γριπης (vlps)

Info

Publication number
CY1107835T1
CY1107835T1 CY20071101598T CY071101598T CY1107835T1 CY 1107835 T1 CY1107835 T1 CY 1107835T1 CY 20071101598 T CY20071101598 T CY 20071101598T CY 071101598 T CY071101598 T CY 071101598T CY 1107835 T1 CY1107835 T1 CY 1107835T1
Authority
CY
Cyprus
Prior art keywords
vlps
virus
representation
type
flu
Prior art date
Application number
CY20071101598T
Other languages
English (en)
Inventor
Jose M Galarza
Theresa E Latham
Original Assignee
Wyeth Holdings Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Holdings Corporation filed Critical Wyeth Holdings Corporation
Publication of CY1107835T1 publication Critical patent/CY1107835T1/el

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16123—Virus like particles [VLP]

Abstract

Περιγράφονται σωματίδια που ομοιάζουν με ιό γρίπης (VLPs) που περιλαμβάνουν τις δομικές πρωτεΐνες ΗΑ, ΝΑ, Μ1 και Μ2. Τα VLPs επίσης δημιουργούνται να περιέχουν Μ1 μόνο, όπως είναι VLPs με Μ1 και οποιαδήποτε ένα ή δύο από τα HA, Na και Μ2. VLPs με ΗΑ από ένα ορότυπο γρίπης και ΝΑ από έναν διαφορετικό ορότυπο γρίπης περιγράφονται επίσης, όπως είναι VLPs στα οποία ένα τμήμα ή σύνολο του ΗΑ ή ΝΑ αντικαθίσταται από μια ετερόλογη χαρακτηριστική ομάδα που δεν παράγεται από ιό γρίπης, έτσι ώστε να περιλαμβάνει χιμαιρικά VLPs.
CY20071101598T 2000-06-23 2007-12-17 Συναθροιση αγριου-τυπου και χιμαιρικων σωματιδιων που ομοιαζουν με ιο γριπης (vlps) CY1107835T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21365600P 2000-06-23 2000-06-23
US28441101P 2001-04-17 2001-04-17
EP01946643A EP1294892B1 (en) 2000-06-23 2001-06-21 Assembly of wild-type and chimeric influenza virus-like particles (vlps)

Publications (1)

Publication Number Publication Date
CY1107835T1 true CY1107835T1 (el) 2013-06-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071101598T CY1107835T1 (el) 2000-06-23 2007-12-17 Συναθροιση αγριου-τυπου και χιμαιρικων σωματιδιων που ομοιαζουν με ιο γριπης (vlps)

Country Status (17)

Country Link
US (2) US7556940B2 (el)
EP (1) EP1294892B1 (el)
JP (1) JP5008244B2 (el)
KR (1) KR100877019B1 (el)
CN (1) CN1196788C (el)
AT (1) ATE376059T1 (el)
AU (2) AU2001268662A1 (el)
BR (1) BRPI0111830B8 (el)
CA (1) CA2410297C (el)
CY (1) CY1107835T1 (el)
DE (1) DE60130987T2 (el)
DK (1) DK1294892T3 (el)
ES (1) ES2295175T3 (el)
IL (1) IL153290A0 (el)
MX (1) MXPA02012254A (el)
PT (1) PT1294892E (el)
WO (1) WO2002000885A2 (el)

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CN1437655A (zh) 2003-08-20
WO2002000885A3 (en) 2002-08-08
CA2410297A1 (en) 2002-01-03
US20090239261A1 (en) 2009-09-24
WO2002000885A9 (en) 2002-05-10
WO2002000885A2 (en) 2002-01-03
US7556940B2 (en) 2009-07-07
PT1294892E (pt) 2008-01-16
AU2001268662A1 (en) 2002-01-08
EP1294892A2 (en) 2003-03-26
IL153290A0 (en) 2003-07-06
DE60130987T2 (de) 2008-07-24
DE60130987D1 (de) 2007-11-29
AU2007201727A1 (en) 2007-05-10
CN1196788C (zh) 2005-04-13
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AU2007201727B2 (en) 2009-06-04
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MXPA02012254A (es) 2003-04-25
BR0111830B1 (pt) 2014-12-02
US8859231B2 (en) 2014-10-14
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