DE69930960D1 - Synthetische virus-ähnliche partikel mit heterologen epitopen. - Google Patents

Synthetische virus-ähnliche partikel mit heterologen epitopen.

Info

Publication number
DE69930960D1
DE69930960D1 DE69930960T DE69930960T DE69930960D1 DE 69930960 D1 DE69930960 D1 DE 69930960D1 DE 69930960 T DE69930960 T DE 69930960T DE 69930960 T DE69930960 T DE 69930960T DE 69930960 D1 DE69930960 D1 DE 69930960D1
Authority
DE
Germany
Prior art keywords
synthetic virus
heterologic
epitopes
particles
related particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69930960T
Other languages
English (en)
Other versions
DE69930960T2 (de
Inventor
U Jansen
C Ling
W Ludmerer
L Mcclements
Xin-Min Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69930960D1 publication Critical patent/DE69930960D1/de
Publication of DE69930960T2 publication Critical patent/DE69930960T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69930960T 1998-12-17 1999-12-14 Synthetische virus-ähnliche partikel mit heterologen epitopen. Expired - Lifetime DE69930960T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11261098P 1998-12-17 1998-12-17
US112610P 1998-12-17
PCT/US1999/029577 WO2000035479A1 (en) 1998-12-17 1999-12-14 Synthetic virus-like particles with heterologous epitopes

Publications (2)

Publication Number Publication Date
DE69930960D1 true DE69930960D1 (de) 2006-05-24
DE69930960T2 DE69930960T2 (de) 2007-04-19

Family

ID=22344867

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69930960T Expired - Lifetime DE69930960T2 (de) 1998-12-17 1999-12-14 Synthetische virus-ähnliche partikel mit heterologen epitopen.

Country Status (7)

Country Link
EP (1) EP1140161B1 (de)
AT (1) ATE323508T1 (de)
AU (1) AU770809B2 (de)
CA (1) CA2354444A1 (de)
DE (1) DE69930960T2 (de)
ES (1) ES2262359T3 (de)
WO (1) WO2000035479A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6908613B2 (en) * 2000-06-21 2005-06-21 Medimmune, Inc. Chimeric human papillomavirus (HPV) L1 molecules and uses therefor
EP1947174A1 (de) * 2000-06-21 2008-07-23 MedImmune, LLC Chimärische menschliche Papillomavirus-L1-Moleküle und Verwendungen davon
DE10137102A1 (de) 2001-07-30 2003-02-27 Deutsches Krebsforsch Polyvalente Vakzine gegen durch Papillomaviren verursachte Erkrankungen, Verfahren zu deren Herstellung und deren Verwendung
WO2009039229A2 (en) 2007-09-18 2009-03-26 Ligocyte Pharmaceuticals, Inc. Method of conferring a protective immune response to norovirus
DK2601970T3 (en) 2006-09-29 2017-02-06 Takeda Vaccines Inc Norovirus vaccine formulations
AU2009279456B2 (en) * 2008-08-08 2015-02-05 Takeda Vaccines, Inc. Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity
AU2012282658B2 (en) 2011-07-11 2014-11-27 Takeda Vaccines, Inc. Parenteral norovirus vaccine formulations
CN114539363B (zh) * 2020-11-26 2023-12-01 中国医学科学院基础医学研究所 一种c端改造的人乳头瘤病毒11型l1蛋白及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618536A (en) * 1992-09-03 1997-04-08 The United States Of America As Represented By The Department Of Health And Human Services Chimeric papillomavirus-like particles
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
AUPM566794A0 (en) * 1994-05-17 1994-06-09 University Of Queensland, The Process and product
US5795754A (en) * 1995-07-19 1998-08-18 Merck & Co., Inc. Synthetic HPV11 virus-like particles
JP2000501285A (ja) * 1995-11-15 2000-02-08 メルク エンド カンパニー インコーポレーテッド 合成ｈｐｖ１１ウイルス様粒子
US5922588A (en) * 1996-10-04 1999-07-13 Merck & Co., Inc. Synthetic HPV16 virus-like particles

Also Published As

Publication number Publication date
EP1140161B1 (de) 2006-04-19
DE69930960T2 (de) 2007-04-19
EP1140161A1 (de) 2001-10-10
ES2262359T3 (es) 2006-11-16
ATE323508T1 (de) 2006-05-15
CA2354444A1 (en) 2000-06-22
AU770809B2 (en) 2004-03-04
EP1140161A4 (de) 2003-05-02
AU2360000A (en) 2000-07-03
WO2000035479A1 (en) 2000-06-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MERCK & CO., INC., RAHWAY, N.J., US