DE69930960D1 - Synthetische virus-ähnliche partikel mit heterologen epitopen. - Google Patents

Synthetische virus-ähnliche partikel mit heterologen epitopen.

Info

Publication number
DE69930960D1
DE69930960D1 DE69930960T DE69930960T DE69930960D1 DE 69930960 D1 DE69930960 D1 DE 69930960D1 DE 69930960 T DE69930960 T DE 69930960T DE 69930960 T DE69930960 T DE 69930960T DE 69930960 D1 DE69930960 D1 DE 69930960D1
Authority
DE
Germany
Prior art keywords
synthetic virus
heterologic
epitopes
particles
related particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69930960T
Other languages
English (en)
Other versions
DE69930960T2 (de
Inventor
U Jansen
C Ling
W Ludmerer
L Mcclements
Xin-Min Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE69930960D1 publication Critical patent/DE69930960D1/de
Application granted granted Critical
Publication of DE69930960T2 publication Critical patent/DE69930960T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69930960T 1998-12-17 1999-12-14 Synthetische virus-ähnliche partikel mit heterologen epitopen. Expired - Lifetime DE69930960T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11261098P 1998-12-17 1998-12-17
US112610P 1998-12-17
PCT/US1999/029577 WO2000035479A1 (en) 1998-12-17 1999-12-14 Synthetic virus-like particles with heterologous epitopes

Publications (2)

Publication Number Publication Date
DE69930960D1 true DE69930960D1 (de) 2006-05-24
DE69930960T2 DE69930960T2 (de) 2007-04-19

Family

ID=22344867

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69930960T Expired - Lifetime DE69930960T2 (de) 1998-12-17 1999-12-14 Synthetische virus-ähnliche partikel mit heterologen epitopen.

Country Status (7)

Country Link
EP (1) EP1140161B1 (de)
AT (1) ATE323508T1 (de)
AU (1) AU770809B2 (de)
CA (1) CA2354444A1 (de)
DE (1) DE69930960T2 (de)
ES (1) ES2262359T3 (de)
WO (1) WO2000035479A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1947174A1 (de) * 2000-06-21 2008-07-23 MedImmune, LLC Chimärische menschliche Papillomavirus-L1-Moleküle und Verwendungen davon
US6908613B2 (en) * 2000-06-21 2005-06-21 Medimmune, Inc. Chimeric human papillomavirus (HPV) L1 molecules and uses therefor
DE10137102A1 (de) * 2001-07-30 2003-02-27 Deutsches Krebsforsch Polyvalente Vakzine gegen durch Papillomaviren verursachte Erkrankungen, Verfahren zu deren Herstellung und deren Verwendung
AU2007303608B2 (en) 2006-09-29 2013-05-02 Takeda Vaccines, Inc. Norovirus vaccine formulations
KR20100083150A (ko) 2007-09-18 2010-07-21 리고사이트 파머슈티컬즈 인코퍼레이티드 노로바이러스에 대한 보호면역반응을 제공하는 방법
AU2009279456B2 (en) * 2008-08-08 2015-02-05 Takeda Vaccines, Inc. Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity
EA035442B1 (ru) 2011-07-11 2020-06-17 Такеда Вэксинс, Инк. Композиции, содержащие буфер, вакцины, которые содержат композиции, содержащие буфер, и пути их применения
CN114539363B (zh) * 2020-11-26 2023-12-01 中国医学科学院基础医学研究所 一种c端改造的人乳头瘤病毒11型l1蛋白及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618536A (en) * 1992-09-03 1997-04-08 The United States Of America As Represented By The Department Of Health And Human Services Chimeric papillomavirus-like particles
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
AUPM566794A0 (en) * 1994-05-17 1994-06-09 University Of Queensland, The Process and product
US5795754A (en) * 1995-07-19 1998-08-18 Merck & Co., Inc. Synthetic HPV11 virus-like particles
DE69631380T2 (de) * 1995-11-15 2004-11-04 Merck & Co., Inc. Synthetische hpv11 virusartige partikel
US5922588A (en) * 1996-10-04 1999-07-13 Merck & Co., Inc. Synthetic HPV16 virus-like particles

Also Published As

Publication number Publication date
CA2354444A1 (en) 2000-06-22
AU770809B2 (en) 2004-03-04
ATE323508T1 (de) 2006-05-15
AU2360000A (en) 2000-07-03
EP1140161B1 (de) 2006-04-19
EP1140161A1 (de) 2001-10-10
EP1140161A4 (de) 2003-05-02
ES2262359T3 (es) 2006-11-16
DE69930960T2 (de) 2007-04-19
WO2000035479A1 (en) 2000-06-22

Similar Documents

Publication Publication Date Title
ES2078375T3 (es) Polimero isobutileno que tiene un grupo insaturado y su preparacion.
ECSP045300A (es) Antígenos virales
WO2000015251A3 (de) Influenzavirus-impfstoffzusammensetzung
ES2170743T3 (es) Oxido de aluminio preparado por via pirogena.
CY1111552T1 (el) Χρηση hpv16 και hpv18 ως εμβολιο εναντι ενος ή περισσοτερων ογκογονικου hpv τυπου 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68
DE69535018D1 (de) Papillomavirus vakzine
AU2001262345A1 (en) Antigenic composition comprising a polycationic peptide and inosine and cytosine
JP2002525392A5 (de)
CY1108666T1 (el) Εξασθενημενα στελεχη του δαγγειου πυρετου και η χρηση τους σε μια συνθεση εμβολιου
DE69930960D1 (de) Synthetische virus-ähnliche partikel mit heterologen epitopen.
FI964791A0 (fi) Titaanidioksidiin perustuvia katalyyttien kantajia
ATE297218T1 (de) Impfstoff gegen mehrere fiv-subtypen
DE60036692D1 (de) Zusammensetzungen und methoden zur detektion einer trypanosoma cruzi infektion
DE69631380D1 (de) Synthetische hpv11 virusartige partikel
BR0009077A (pt) Antìgenos de tuberculose e métodos de uso dos mesmos
ATE260114T1 (de) Synthetische hpv-16 virusähnliche partikel
ES2152752T3 (es) Recipiente de residuos con biocida.
EP0471457A3 (de) Herpesvirus-Vektor, der ein Epitope des Maul- und Klauenseuchenviruses exprimiert
IT1303534B1 (it) Procedimento per controllare i riporti di adesivo sui fondi aperti disacchi o borse.
DE60008291D1 (de) Oralreinigungsmittel
DE60013887D1 (de) Zahnpasta
SI1572233T1 (sl) Uporaba HPV16 in HPV18 kot cepivo proti enemu ali več onkogenih HPV tipa 31,33,35,39,45,51,52,56,58,59,66,68
DE59106111D1 (de) TYP II-Restriktionsendonuklease SwaI.
AU7439991A (en) Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
ITVR940073V0 (it) Conglomerato di materiali atto alla formazione di blocchi simili al tufo, sezionabili e/o variamente lavorabili

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MERCK & CO., INC., RAHWAY, N.J., US