JP2003510366A5 - - Google Patents
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- JP2003510366A5 JP2003510366A5 JP2001527810A JP2001527810A JP2003510366A5 JP 2003510366 A5 JP2003510366 A5 JP 2003510366A5 JP 2001527810 A JP2001527810 A JP 2001527810A JP 2001527810 A JP2001527810 A JP 2001527810A JP 2003510366 A5 JP2003510366 A5 JP 2003510366A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polypeptide
- composition according
- seq
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 description 12
- 229920001184 polypeptide Polymers 0.000 description 6
- 102000004196 processed proteins & peptides Human genes 0.000 description 6
- 108090000765 processed proteins & peptides Proteins 0.000 description 6
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- 150000001413 amino acids Chemical class 0.000 description 3
- 210000004881 tumor cell Anatomy 0.000 description 3
- 108060003951 Immunoglobulin Proteins 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 102000018358 immunoglobulin Human genes 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15793399P | 1999-10-06 | 1999-10-06 | |
| US60/157,933 | 1999-10-06 | ||
| US18180700P | 2000-02-11 | 2000-02-11 | |
| US60/181,807 | 2000-02-11 | ||
| US21568800P | 2000-06-30 | 2000-06-30 | |
| US60/215,688 | 2000-06-30 | ||
| PCT/US2000/027579 WO2001024811A1 (en) | 1999-10-06 | 2000-10-05 | April receptor (bcma) and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011002461A Division JP2011079863A (ja) | 1999-10-06 | 2011-01-07 | Ａｐｒｉｌレセプター（ｂｃｍａ）およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003510366A JP2003510366A (ja) | 2003-03-18 |
| JP2003510366A5 true JP2003510366A5 (enExample) | 2007-10-25 |
| JP4880155B2 JP4880155B2 (ja) | 2012-02-22 |
Family
ID=27388102
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001527810A Expired - Fee Related JP4880155B2 (ja) | 1999-10-06 | 2000-10-05 | Ａｐｒｉｌレセプター（ｂｃｍａ）およびその使用 |
| JP2011002461A Pending JP2011079863A (ja) | 1999-10-06 | 2011-01-07 | Ａｐｒｉｌレセプター（ｂｃｍａ）およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011002461A Pending JP2011079863A (ja) | 1999-10-06 | 2011-01-07 | Ａｐｒｉｌレセプター（ｂｃｍａ）およびその使用 |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7276241B2 (enExample) |
| EP (3) | EP1223964B1 (enExample) |
| JP (2) | JP4880155B2 (enExample) |
| KR (1) | KR100759295B1 (enExample) |
| CN (1) | CN1263507C (enExample) |
| AT (1) | ATE360434T1 (enExample) |
| AU (1) | AU776852B2 (enExample) |
| BG (1) | BG65473B1 (enExample) |
| BR (1) | BR0014583A (enExample) |
| CA (1) | CA2386463C (enExample) |
| CZ (1) | CZ297633B6 (enExample) |
| DE (1) | DE60034586T2 (enExample) |
| DK (1) | DK1223964T3 (enExample) |
| EA (1) | EA005601B1 (enExample) |
| EE (1) | EE05212B1 (enExample) |
| GE (1) | GEP20043375B (enExample) |
| HK (1) | HK1044710B (enExample) |
| HU (1) | HUP0203567A2 (enExample) |
| IL (3) | IL148839A0 (enExample) |
| IS (1) | IS6322A (enExample) |
| MX (1) | MXPA02003393A (enExample) |
| NO (1) | NO331683B1 (enExample) |
| NZ (1) | NZ517907A (enExample) |
| PL (1) | PL204010B1 (enExample) |
| RS (1) | RS51602B (enExample) |
| SK (1) | SK286331B6 (enExample) |
| TR (1) | TR200200912T2 (enExample) |
| UA (1) | UA74798C2 (enExample) |
| WO (1) | WO2001024811A1 (enExample) |
| ZA (1) | ZA200202578B (enExample) |
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| CA2408617A1 (en) * | 2000-05-12 | 2001-11-22 | Amgen Inc. | Methods and compositions of matter concerning april/g70, bcma, blys/agp-3, and taci |
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| US7879328B2 (en) | 2000-06-16 | 2011-02-01 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator |
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| EP2272868B1 (en) * | 2003-06-05 | 2015-03-04 | Genentech, Inc. | Combination therapy for B cell disorders |
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| PT1742966E (pt) | 2004-04-22 | 2014-02-05 | Agensys Inc | Anticorpos e moléculas derivadas daí que se ligam às proteínas steap-1 |
| CN1786016B (zh) * | 2004-12-09 | 2010-12-29 | 中国人民解放军军事医学科学院基础医学研究所 | 一种人工构建的生物活性分子及其制备方法 |
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| AU2006278227B2 (en) | 2005-08-09 | 2011-10-20 | Ares Trading S.A. | Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules |
| ZA200801354B (en) | 2005-08-09 | 2009-08-26 | Ares Trading Sa | Methods for treating B-cell malignancies using TACI-lg fusion molecule |
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| EA015860B1 (ru) | 2005-10-13 | 2011-12-30 | Хьюман Дженом Сайенсиз, Инк. | Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа |
| CA2629306A1 (en) | 2005-11-23 | 2007-05-31 | Genentech, Inc. | Methods and compositions related to b cell assays |
| US8211649B2 (en) | 2006-03-31 | 2012-07-03 | Human Genome Sciences, Inc. | Methods of diagnosing and prognosing hodgkin's lymphoma |
| EA015342B1 (ru) | 2006-05-15 | 2011-06-30 | Арес Трейдинг С.А. | Способы лечения аутоиммунных заболеваний с использованием слитой молекулы taci-ig |
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| MD23Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare |
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| TWI679212B (zh) | 2011-11-15 | 2019-12-11 | 美商安進股份有限公司 | 針對ｂｃｍａ之e3以及ｃｄ３的結合分子 |
| WO2013171296A1 (en) | 2012-05-16 | 2013-11-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Diagnostic and treatment of sarcoidosis |
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| PL2953972T3 (pl) | 2013-02-05 | 2021-03-08 | Engmab Sàrl | Metoda wyboru przeciwciał przeciwko bcma |
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