ATE446510T1 - Kontrolle des wachstums und der reparatur von gastrointestinalgewebe durch gastrokine - Google Patents

Kontrolle des wachstums und der reparatur von gastrointestinalgewebe durch gastrokine

Info

Publication number
ATE446510T1
ATE446510T1 AT02728619T AT02728619T ATE446510T1 AT E446510 T1 ATE446510 T1 AT E446510T1 AT 02728619 T AT02728619 T AT 02728619T AT 02728619 T AT02728619 T AT 02728619T AT E446510 T1 ATE446510 T1 AT E446510T1
Authority
AT
Austria
Prior art keywords
protein
repair
control
growth
gastrokine
Prior art date
Application number
AT02728619T
Other languages
English (en)
Inventor
Gary Toback
Terrence E Martin
Margaret Walsh-Reitz
Original Assignee
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25234151&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE446510(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Chicago filed Critical Univ Chicago
Application granted granted Critical
Publication of ATE446510T1 publication Critical patent/ATE446510T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02728619T 2001-03-29 2002-03-29 Kontrolle des wachstums und der reparatur von gastrointestinalgewebe durch gastrokine ATE446510T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/821,726 US6734289B2 (en) 2001-03-29 2001-03-29 Gastrokines and derived peptides including inhibitors
PCT/US2002/009885 WO2002078640A2 (en) 2001-03-29 2002-03-29 Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors

Publications (1)

Publication Number Publication Date
ATE446510T1 true ATE446510T1 (de) 2009-11-15

Family

ID=25234151

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02728619T ATE446510T1 (de) 2001-03-29 2002-03-29 Kontrolle des wachstums und der reparatur von gastrointestinalgewebe durch gastrokine

Country Status (10)

Country Link
US (4) US6734289B2 (de)
EP (2) EP1423409A4 (de)
JP (3) JP4281947B2 (de)
AT (1) ATE446510T1 (de)
AU (2) AU2002258663B2 (de)
CA (2) CA2442635A1 (de)
DE (1) DE60234103D1 (de)
ES (1) ES2332882T3 (de)
MX (2) MXPA03008855A (de)
WO (2) WO2002092758A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6734289B2 (en) * 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
US7629317B2 (en) 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
DE102004047968A1 (de) * 2004-10-01 2006-04-06 B.R.A.H.M.S Ag Bestimmung von Gastrokine 1 (GKN1) als Biomarker für Entzündungen und Infektionen
AU2006244080C1 (en) * 2005-05-10 2012-02-02 The University Of Chicago Use of peptides derived from the growth factor AMP-18 for the treatment of mucositis
US8017576B2 (en) * 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis
ATE526983T1 (de) * 2005-05-10 2011-10-15 Univ Chicago Verwendung von peptiden aus dem wachstumsfaktors amp-18 zur behandlung von stomatitis
EP2522717B1 (de) 2006-01-04 2014-04-02 Baxter International Inc Oligopeptid-freie Zellkulturmedien
EP2082674A1 (de) 2008-01-22 2009-07-29 Trelleborg Building Systems AB Wasserdichtes Dichtungsprofil
CN101945613B (zh) * 2008-02-18 2014-08-13 皇家飞利浦电子股份有限公司 为患者用药
EP3284476B1 (de) 2012-12-19 2019-09-25 Lumen Bio LLC Verwendung eines gastrokinproteins
AU2018215245B2 (en) * 2017-02-06 2024-07-11 Resiliun B.V. Interaction between C-peptides and elastin receptor, a model for understanding vascular disease
KR102590757B1 (ko) * 2020-12-11 2023-10-17 가톨릭대학교 산학협력단 GKN1(Gastrokine 1) 특이적 항체 및 이의 용도

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135856A (en) 1987-06-24 1992-08-04 Arch Development Corp. Production of autocrine growth factors
US5476922A (en) 1987-06-24 1995-12-19 Arch Development Corporation Methods and compositions for the preparation and use of autocrine growth factors
US5102870A (en) * 1989-04-14 1992-04-07 Schering Ag Treatment and prevention of oral mucositis with growth factors
JP2938129B2 (ja) 1989-05-02 1999-08-23 武田薬品工業株式会社 虚血性腎疾患の予防・治療剤
US5644026A (en) * 1994-05-03 1997-07-01 La Jolla Cancer Research Foundation Epitaxin, a cell motility factor
JPH08231413A (ja) 1994-12-29 1996-09-10 Mochida Pharmaceut Co Ltd 臓器障害に基づく疾患の予防・治療剤
CA2218864A1 (en) 1995-04-21 1996-10-24 Tsutomu Yonehana Agent for preventing and/or treating ischemic diseases
JP3681405B2 (ja) * 1997-02-21 2005-08-10 タカラバイオ株式会社 癌関連遺伝子
US20030054359A1 (en) * 1997-06-16 2003-03-20 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO1999007840A1 (en) * 1997-08-06 1999-02-18 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
AU4834999A (en) * 1998-06-26 2000-01-17 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
BR0008188A (pt) 1999-01-21 2002-02-13 Metamorphix Inc Inibidores de fator de diferenciação de crescimento e usos para os mesmos
ATE478145T1 (de) * 1999-06-02 2010-09-15 Genentech Inc Sekretierte und transmembran polypeptide und dafür kodierende nukleinsäuren
PT1185648E (pt) * 1999-06-22 2007-06-29 Genentech Inc Métodos e composições para a inibição do crescimento de células neoplásicas.
US6734289B2 (en) * 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
US7629317B2 (en) * 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
US8017576B2 (en) * 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis

Also Published As

Publication number Publication date
EP1423409A2 (de) 2004-06-02
US7557083B2 (en) 2009-07-07
ES2332882T3 (es) 2010-02-15
MXPA03008861A (es) 2004-10-15
CA2442635A1 (en) 2002-11-21
EP1415154A4 (de) 2004-12-22
JP2004532037A (ja) 2004-10-21
CA2442684C (en) 2013-11-19
CA2442684A1 (en) 2002-10-10
EP1423409A4 (de) 2005-12-07
WO2002092758A3 (en) 2004-04-01
EP1415154A2 (de) 2004-05-06
EP1415154B1 (de) 2009-10-21
JP2004537284A (ja) 2004-12-16
WO2002092758A9 (en) 2004-06-24
JP4295516B2 (ja) 2009-07-15
WO2002092758A8 (en) 2003-02-20
US6734289B2 (en) 2004-05-11
AU2002258663B2 (en) 2008-02-21
US20050054564A1 (en) 2005-03-10
AU2002303199B2 (en) 2008-03-13
US20130086701A1 (en) 2013-04-04
US8278269B2 (en) 2012-10-02
DE60234103D1 (de) 2009-12-03
US8791068B2 (en) 2014-07-29
WO2002078640A3 (en) 2004-03-04
WO2002078640A2 (en) 2002-10-10
JP4281947B2 (ja) 2009-06-17
JP2007217422A (ja) 2007-08-30
US20050065328A1 (en) 2005-03-24
MXPA03008855A (es) 2004-12-06
WO2002092758A2 (en) 2002-11-21
US20030017548A1 (en) 2003-01-23

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