|
US6379971B1
(en)
|
1998-02-24 |
2002-04-30 |
Target Discovery, Inc. |
Methods for sequencing proteins
|
|
DE69912444T3
(de)
*
|
1998-08-25 |
2010-05-06 |
University Of Washington, Seattle |
Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
|
|
JP2003524394A
(ja)
*
|
1999-02-11 |
2003-08-19 |
マキシジェン， インコーポレイテッド |
ハイスループット質量分析法
|
|
US6629040B1
(en)
|
1999-03-19 |
2003-09-30 |
University Of Washington |
Isotope distribution encoded tags for protein identification
|
|
AU774776B2
(en)
*
|
1999-04-15 |
2004-07-08 |
University Of Virginia Patent Foundation |
Proteome mining
|
|
US6764817B1
(en)
|
1999-04-20 |
2004-07-20 |
Target Discovery, Inc. |
Methods for conducting metabolic analyses
|
|
US6716636B1
(en)
|
1999-04-20 |
2004-04-06 |
Target Discovery, Inc. |
Methods for sequencing proteins
|
|
US6937330B2
(en)
|
1999-04-23 |
2005-08-30 |
Ppd Biomarker Discovery Sciences, Llc |
Disposable optical cuvette cartridge with low fluorescence material
|
|
AU773329B2
(en)
*
|
1999-05-14 |
2004-05-20 |
Proteomedica Ab |
Materials and methods relating to disease diagnosis
|
|
US6960439B2
(en)
|
1999-06-28 |
2005-11-01 |
Source Precision Medicine, Inc. |
Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
|
|
US6692916B2
(en)
|
1999-06-28 |
2004-02-17 |
Source Precision Medicine, Inc. |
Systems and methods for characterizing a biological condition or agent using precision gene expression profiles
|
|
US6687395B1
(en)
*
|
1999-07-21 |
2004-02-03 |
Surromed, Inc. |
System for microvolume laser scanning cytometry
|
|
US6783929B1
(en)
|
1999-11-02 |
2004-08-31 |
Chiron Corporation |
Biological sample component purification and differential display
|
|
DE60030882T2
(de)
*
|
2000-01-06 |
2007-04-05 |
Caliper Life Sciences, Inc., Mountain View |
Vorrichtungen und verfahren für hochdurchsatz-probenentnahme und analyse
|
|
CA2403296A1
(en)
*
|
2000-04-10 |
2001-10-18 |
Benjamin F. Cravatt |
Proteomic analysis using activity-based probe libraries
|
|
DE10021737C2
(de)
*
|
2000-05-04 |
2002-10-17 |
Hermann Haller |
Verfahren und Vorrichtung zur qualitativen und/oder quantitativen Bestimmung eines Protein- und/oder Peptidmusters einer Flüssigkeitsprobe, die dem menschlichen oder tierischen Körper entnommen wird
|
|
ATE344456T1
(de)
*
|
2000-05-05 |
2006-11-15 |
Purdue Research Foundation |
Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen
|
|
US7148058B2
(en)
|
2000-06-05 |
2006-12-12 |
Chiron Corporation |
Protein microarrays on mirrored surfaces for performing proteomic analyses
|
|
US7153682B2
(en)
|
2000-06-05 |
2006-12-26 |
Chiron Corporation |
Microarrays on mirrored substrates for performing proteomic analyses
|
|
DE10027794A1
(de)
*
|
2000-06-07 |
2001-12-13 |
Basf Ag |
Verfahren zur Analyse Enzym-katalysierter Umsetzungen mit MALDI-TOF-Massenspektrometrie
|
|
WO2001094910A2
(de)
*
|
2000-06-07 |
2001-12-13 |
Basf Aktiengesellschaft |
Verfahren zur qualitativen und quantitativen analyse komplexer gemische chemischer verbindungen mit maldi-tof-massenspektrometrie
|
|
WO2001094935A2
(en)
|
2000-06-09 |
2001-12-13 |
Mds Proteomics, Inc. |
Labeling of proteomic samples during proteolysis for quantitation and sample multiplexing
|
|
JP2004503780A
(ja)
|
2000-06-12 |
2004-02-05 |
ユニバーシティ オブ ワシントン |
リンペプチドの選択的標識および単離ならびにプロテオーム分析への適用
|
|
US7567870B1
(en)
|
2000-07-31 |
2009-07-28 |
Institute For Systems Biology |
Multiparameter analysis for predictive medicine
|
|
WO2002014867A2
(en)
*
|
2000-08-11 |
2002-02-21 |
Agilix Corporation |
Ultra-sensitive detection systems
|
|
US20020123055A1
(en)
*
|
2000-08-25 |
2002-09-05 |
Estell David A. |
Mass spectrometric analysis of biopolymers
|
|
DE10043470B4
(de)
*
|
2000-09-04 |
2006-01-19 |
Mpb Meltec Patent- Und Beteiligungsgesellschaft Mbh |
Verfahren zur Identifizierung von zellspezifischen Proteinen
|
|
WO2002029032A2
(en)
*
|
2000-09-30 |
2002-04-11 |
Diversa Corporation |
Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating
|
|
SE0003566D0
(sv)
*
|
2000-10-02 |
2000-10-02 |
Amersham Pharm Biotech Ab |
A method for the quantitative determination of one or more compounds
|
|
EP1325322A2
(en)
*
|
2000-10-03 |
2003-07-09 |
Dionex Corporation |
Method and system for peak parking in liquid chromatography-mass spectrometer (lc-ms) analysis
|
|
WO2002066952A2
(en)
|
2000-10-19 |
2002-08-29 |
Target Discovery, Inc |
Mass defect labeling for the determination of oligomer sequences
|
|
CA2426731A1
(en)
|
2000-10-23 |
2002-06-20 |
Genetics Institute, Llc. |
Acid-labile isotope-coded extractant (alice) and its use in quantitative mass spectrometric analysis of protein mixtures
|
|
ATE405839T1
(de)
|
2000-10-23 |
2008-09-15 |
Genetics Inst Llc |
Isotop-kodierte ionisierung-förderende reagenzien zur hochdurchsatz protein identifikation und quantifikation mit massenspectrometrie
|
|
US20020164649A1
(en)
*
|
2000-10-25 |
2002-11-07 |
Rajendra Singh |
Mass tags for quantitative analysis
|
|
SE0004094D0
(sv)
*
|
2000-11-09 |
2000-11-09 |
Amersham Pharm Biotech Ab |
A method for the quantification of carbohudrates
|
|
US6787761B2
(en)
*
|
2000-11-27 |
2004-09-07 |
Surromed, Inc. |
Median filter for liquid chromatography-mass spectrometry data
|
|
US20020095260A1
(en)
*
|
2000-11-28 |
2002-07-18 |
Surromed, Inc. |
Methods for efficiently mining broad data sets for biological markers
|
|
US6797523B2
(en)
|
2000-11-30 |
2004-09-28 |
Affinium Pharmaceuticals, Inc. |
Methods for systematic identification of protein—protein interactions
|
|
US20020090652A1
(en)
*
|
2000-12-22 |
2002-07-11 |
Fu Emil Wei-Ming |
Inverse labeling method for the rapid identification of marker/target proteins
|
|
US20020115056A1
(en)
|
2000-12-26 |
2002-08-22 |
Goodlett David R. |
Rapid and quantitative proteome analysis and related methods
|
|
AU2002248323A1
(en)
*
|
2001-01-12 |
2002-07-24 |
The Regents Of The University Of California |
Stable isotope, site-specific mass tagging for protein identification
|
|
US7166436B2
(en)
*
|
2001-01-26 |
2007-01-23 |
Syngenta Participations, Ag |
Differential labeling for quantitative analysis of complex protein mixtures
|
|
US6969757B2
(en)
|
2001-01-26 |
2005-11-29 |
Syngenta Participations Ag |
Differential labeling for quantitative analysis of complex protein mixtures
|
|
US7083987B2
(en)
|
2001-02-05 |
2006-08-01 |
Activx Biosciences, Inc. |
Activity based probe analysis
|
|
US6818454B2
(en)
|
2001-02-16 |
2004-11-16 |
Battelle Memorial Institute |
Phosphoprotein binding agents and methods of their use
|
|
ATE476654T1
(de)
|
2001-03-02 |
2010-08-15 |
Activx Biosciences Inc |
Plattform für protein-profiling
|
|
ES2242864T3
(es)
*
|
2001-03-22 |
2005-11-16 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. |
Procedimientos y aparatos para el analisis cualitativo y cuantitativo sin gel de proteoma, y sus usos.
|
|
CN1273615C
(zh)
*
|
2001-04-03 |
2006-09-06 |
塞莫费尼根股份有限公司 |
用于简化复合肽混合物的方法和试剂盒
|
|
KR20030031911A
(ko)
*
|
2001-04-19 |
2003-04-23 |
싸이퍼젠 바이오시스템즈, 인코포레이티드 |
질량 분석법과 친화성 태그를 이용한 생물분자 특성화
|
|
US7045296B2
(en)
*
|
2001-05-08 |
2006-05-16 |
Applera Corporation |
Process for analyzing protein samples
|
|
US7183116B2
(en)
*
|
2001-05-14 |
2007-02-27 |
The Institute For Systems Biology |
Methods for isolation and labeling of sample molecules
|
|
JP2005502030A
(ja)
*
|
2001-05-29 |
2005-01-20 |
リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
タンパク質解析のシステムおよび方法
|
|
CA2349265A1
(en)
*
|
2001-05-30 |
2002-11-30 |
Andrew Emili |
Protein expression profile database
|
|
US20030068825A1
(en)
*
|
2001-07-13 |
2003-04-10 |
Washburn Michael P. |
System and method of determining proteomic differences
|
|
US6800449B1
(en)
|
2001-07-13 |
2004-10-05 |
Syngenta Participations Ag |
High throughput functional proteomics
|
|
ATE305938T1
(de)
*
|
2001-07-16 |
2005-10-15 |
Harvard College |
Nicht auf affinität basierende, isotopenmarkierte peptide und verfahren zu deren anwendung
|
|
JP3935487B2
(ja)
|
2001-07-16 |
2007-06-20 |
フーベルト・ケスター |
捕獲化合物、その収集物、ならびにプロテオームおよび複合組成物の分析方法
|
|
US7343247B2
(en)
|
2001-07-30 |
2008-03-11 |
The Institute For Systems Biology |
Methods of classifying drug responsiveness using multiparameter analysis
|
|
ATE508361T1
(de)
*
|
2001-08-14 |
2011-05-15 |
Harvard College |
Absolute quantifizierung von proteinen und modifizierten formen davon mittels mehrstufiger massenspektrometrie
|
|
US6873915B2
(en)
*
|
2001-08-24 |
2005-03-29 |
Surromed, Inc. |
Peak selection in multidimensional data
|
|
CA2461587C
(en)
*
|
2001-09-27 |
2011-04-26 |
Purdue Research Foundation |
Materials and methods for controlling isotope effects during fractionation of analytes
|
|
US20030078739A1
(en)
*
|
2001-10-05 |
2003-04-24 |
Surromed, Inc. |
Feature list extraction from data sets such as spectra
|
|
US6756586B2
(en)
|
2001-10-15 |
2004-06-29 |
Vanderbilt University |
Methods and apparatus for analyzing biological samples by mass spectrometry
|
|
DE10153631B4
(de)
*
|
2001-10-31 |
2006-04-13 |
Lottspeich, Friedrich, Dr. |
Verfahren zum Vergleich zweier Proteinzustände
|
|
WO2003040288A2
(de)
*
|
2001-11-09 |
2003-05-15 |
Bayer Healthcare Ag |
Isotopencodierte affinitätsmarker 3
|
|
DE10154744A1
(de)
*
|
2001-11-09 |
2003-05-22 |
Bayer Ag |
Isotopencodierte Affinitätsmarker
|
|
CN1612936A
(zh)
|
2001-11-09 |
2005-05-04 |
苏尔斯精细医药公司 |
利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态
|
|
CA2466356A1
(en)
*
|
2001-11-09 |
2003-05-15 |
Bayer Healthcare Ag |
Isotopically coded affinity marker 2
|
|
US20030129760A1
(en)
*
|
2001-11-13 |
2003-07-10 |
Aguilera Frank Reinaldo Morales |
Mass intensity profiling system and uses thereof
|
|
US20030091976A1
(en)
*
|
2001-11-14 |
2003-05-15 |
Ciphergen Biosystems, Inc. |
Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry
|
|
DE10158860B4
(de)
|
2001-11-30 |
2007-04-05 |
Bruker Daltonik Gmbh |
Massenspektrometrische Proteingemischanalyse
|
|
EP1319954A1
(en)
*
|
2001-12-12 |
2003-06-18 |
Centre National de Genotypage |
Methods for protein analysis using protein capture arrays
|
|
US7623969B2
(en)
|
2002-01-31 |
2009-11-24 |
The Institute For Systems Biology |
Gene discovery for the system assignment of gene function
|
|
WO2003068919A2
(en)
*
|
2002-02-12 |
2003-08-21 |
The Regents Of The University Of California |
Non-invasive method for measuring rates of biosynthesis of biological molecules by label incorporation
|
|
EP2317307B1
(en)
*
|
2002-02-14 |
2013-11-20 |
Ajinomoto Co., Inc. |
Method of analyzing amino- and/or imino-functional compounds, and analytical reagent
|
|
EP1502102B1
(en)
*
|
2002-03-11 |
2009-01-14 |
caprotec bioanalytics GmbH |
Compounds and methods for analyzing the proteome
|
|
US7288382B2
(en)
|
2002-03-14 |
2007-10-30 |
The Board Of Trustees Od The Leland Stanford Junior University |
Methods for structural analysis of proteins
|
|
EP1489411A4
(en)
*
|
2002-03-25 |
2007-03-14 |
Teijin Ltd |
TECHNIQUE FOR DETERMINING COENZYMES IN A BIOLOGICAL SAMPLE
|
|
WO2003087834A2
(en)
*
|
2002-04-08 |
2003-10-23 |
Affinium Pharmaceuticals, Inc. |
High throughput analysis of recombinant proteins in multi-well plates
|
|
WO2003095978A2
(en)
*
|
2002-05-09 |
2003-11-20 |
Surromed, Inc. |
Methods for time-alignment of liquid chromatography-mass spectrometry data
|
|
US20050221500A1
(en)
*
|
2002-05-20 |
2005-10-06 |
Purdue Research Foundation |
Protein identification from protein product ion spectra
|
|
US20040229294A1
(en)
|
2002-05-21 |
2004-11-18 |
Po-Ying Chan-Hui |
ErbB surface receptor complexes as biomarkers
|
|
US7052916B2
(en)
*
|
2002-05-24 |
2006-05-30 |
Immunex Corporation |
Polypeptide analyses using stable isotope labeling
|
|
GB0212522D0
(en)
*
|
2002-05-31 |
2002-07-10 |
Shimadzu Res Lab Europe Ltd |
Selective binding and analysis of macromolecules
|
|
US7183118B2
(en)
|
2002-06-03 |
2007-02-27 |
The Institute For Systems Biology |
Methods for quantitative proteome analysis of glycoproteins
|
|
US7655433B2
(en)
|
2002-06-04 |
2010-02-02 |
The Institute For Systems Biology |
Methods for high-throughput and quantitative proteome analysis
|
|
AU2003233498A1
(en)
*
|
2002-06-10 |
2003-12-22 |
Phynexus, Inc. |
Biomolecule open channel solid phase extraction systems and methods
|
|
DE10227599B4
(de)
*
|
2002-06-20 |
2005-04-28 |
Proteome Factory Ag |
Verfahren und Reagenz zur spezifischen Identifizierung und Quantifizierung von einem oder mehreren Proteinen in einer Probe
|
|
WO2004002950A1
(ja)
*
|
2002-06-28 |
2004-01-08 |
Shimadzu Corporation |
スルフェニル化合物、ラベル化試薬、及びペプチドの解析方法
|
|
EP1541580B1
(en)
|
2002-07-10 |
2013-02-27 |
Seikagaku Corporation |
Sulfotransferase inhibitors
|
|
CA2393726A1
(en)
*
|
2002-07-16 |
2004-01-16 |
Steven J. Locke |
Quantitative proteomics via isotopically differentiated derivatization
|
|
GB0305796D0
(en)
|
2002-07-24 |
2003-04-16 |
Micromass Ltd |
Method of mass spectrometry and a mass spectrometer
|
|
US7409296B2
(en)
*
|
2002-07-29 |
2008-08-05 |
Geneva Bioinformatics (Genebio), S.A. |
System and method for scoring peptide matches
|
|
US20060094057A1
(en)
*
|
2002-07-30 |
2006-05-04 |
Maro K. Hellerstein |
Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry
|
|
US7501286B2
(en)
|
2002-08-14 |
2009-03-10 |
President And Fellows Of Harvard College |
Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry
|
|
US7473535B2
(en)
|
2002-08-20 |
2009-01-06 |
The Institute For Systems Biology |
Chemical reagents and methods for detection and quantification of proteins in complex mixtures
|
|
CA2498352C
(en)
*
|
2002-09-12 |
2011-05-10 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
A method for the identification of drug targets
|
|
US20050233307A1
(en)
*
|
2002-09-12 |
2005-10-20 |
Kyle Gee |
Site-specific labeling of affinity tags in fusion proteins
|
|
AU2003286553A1
(en)
|
2002-10-18 |
2004-05-04 |
Promega Corporation |
Methods for separating molecules
|
|
US6944549B2
(en)
*
|
2002-10-25 |
2005-09-13 |
Syngenta Participations Ag |
Method and apparatus for automated detection of peaks in spectroscopic data
|
|
EP1579187B1
(en)
|
2002-10-29 |
2012-12-19 |
Target Discovery, Inc. |
Method for increasing ionization efficiency in mass spectroscopy
|
|
US7846748B2
(en)
|
2002-12-02 |
2010-12-07 |
The University Of North Carolina At Chapel Hill |
Methods of quantitation and identification of peptides and proteins
|
|
US7109040B2
(en)
*
|
2002-12-13 |
2006-09-19 |
Agilent Technologies, Inc. |
Modular isotope coding approach to proteomic analysis
|
|
US7425451B2
(en)
|
2002-12-13 |
2008-09-16 |
Agilent Technologies, Inc. |
Triazine derivatives as universal peptide isotope tag reagents (U-PIT)
|
|
US20060105343A1
(en)
*
|
2003-01-09 |
2006-05-18 |
Children's Medical Center Corporation |
Methods for diagnosis and prognosis of cancer
|
|
US7422865B2
(en)
*
|
2003-01-13 |
2008-09-09 |
Agilent Technologies, Inc. |
Method of identifying peptides in a proteomic sample
|
|
EP2259068B1
(en)
*
|
2003-01-16 |
2013-08-14 |
caprotec bioanalytics GmbH |
Capture compounds and methods for analyzing the proteome
|
|
JP4613299B2
(ja)
*
|
2003-01-30 |
2011-01-12 |
ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド |
分析物分析に関する方法、混合物、キット、および組成物
|
|
WO2004079370A1
(en)
*
|
2003-03-03 |
2004-09-16 |
Universiteit Leiden |
Analysis of the proteome of a living cell by labelling the proteins in the intact cell
|
|
TW200508606A
(en)
*
|
2003-03-07 |
2005-03-01 |
Nard Kenkyusho Kk |
Method of finding molecular weight of phosphoric acid monoester compound, and additive for mass spectrometric measurement
|
|
EP1616034A4
(en)
|
2003-04-01 |
2008-12-03 |
Activx Biosciences Inc |
ACYL PHOSPHATE AND PHOSPHONATE EASTS AND PROCESSES FOR THEIR SYNTHESIS AND USE IN PROTEAM ANALYSIS
|
|
WO2004097372A2
(en)
|
2003-04-28 |
2004-11-11 |
The Regents Of The University Of California |
Element-coded affinity tags
|
|
US7267994B2
(en)
|
2003-04-28 |
2007-09-11 |
Regents Of The University Of California |
Element-coded affinity tags
|
|
GB0311961D0
(en)
|
2003-05-23 |
2003-06-25 |
Health Prot Agency |
Mass-based toxin assay and substrates therefor
|
|
WO2005042559A2
(en)
*
|
2003-06-06 |
2005-05-12 |
President And Fellows Of Harvard College |
Capture and release based isotope tagged peptides and methods for using the same
|
|
CA2529863A1
(en)
*
|
2003-06-17 |
2004-12-23 |
Vib Vzw |
Peptide combos and their uses
|
|
GB0314209D0
(en)
*
|
2003-06-19 |
2003-07-23 |
Amersham Biosciences Ab |
Novel MS reagents
|
|
US7794947B2
(en)
|
2003-07-10 |
2010-09-14 |
Institute For Systems Biology |
Affinity capture of peptides by microarray and related methods
|
|
FR2857451B1
(fr)
*
|
2003-07-11 |
2005-09-30 |
Commissariat Energie Atomique |
Procede et dispositif pour l'analyse de milieux reactionnels vivants
|
|
WO2005019470A2
(en)
*
|
2003-08-11 |
2005-03-03 |
Monogram Biosciences, Inc. |
Detecting and profiling molecular complexes
|
|
US7485435B2
(en)
*
|
2004-08-30 |
2009-02-03 |
Perkinelmer Las, Inc. |
Simultaneous detection of metabolic enzyme activity and metabolite levels
|
|
WO2005022156A1
(ja)
*
|
2003-08-29 |
2005-03-10 |
Reverse Proteomics Research Institute Co., Ltd. |
タンパク質の固定化方法
|
|
US20050048499A1
(en)
*
|
2003-08-29 |
2005-03-03 |
Perkin Elmer Life Sciences, Inc. |
Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns
|
|
US7081623B2
(en)
|
2003-09-05 |
2006-07-25 |
Lucent Technologies Inc. |
Wafer-based ion traps
|
|
US20050074895A1
(en)
*
|
2003-09-05 |
2005-04-07 |
Bio-Rad Laboratories, Inc. |
Alkyl-substituted vinyl pyridines for mass-coded tagging of proteins
|
|
WO2005031304A2
(en)
*
|
2003-09-22 |
2005-04-07 |
Becton, Dickinson And Company |
Quantification of analytes using internal standards
|
|
US7145019B2
(en)
|
2003-10-16 |
2006-12-05 |
Ambergen, Inc. |
Photocleavable isotope-coded affinity tags
|
|
US7348416B2
(en)
*
|
2003-11-21 |
2008-03-25 |
Applera Corporation |
Selective capture and enrichment of proteins expressed on the cell surface
|
|
EP1686372A4
(en)
*
|
2003-11-21 |
2009-04-01 |
Eisai R&D Man Co Ltd |
QUANTIFICATION METHOD USING AN ISOTOPE-MARKED INTERNAL CALIBRATION, ANALYSIS SYSTEM FOR EXECUTING THE QUANTIFICATION METHOD AND ASSOCIATED SEPARATION PROGRAM
|
|
US20050202406A1
(en)
*
|
2003-11-25 |
2005-09-15 |
The Regents Of The University Of California |
Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems
|
|
US7307169B2
(en)
|
2004-01-05 |
2007-12-11 |
Applera Corporation |
Isotopically enriched N-substituted piperazines and methods for the preparation thereof
|
|
US7355045B2
(en)
|
2004-01-05 |
2008-04-08 |
Applera Corporation |
Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof
|
|
EP1708758A4
(en)
*
|
2004-01-15 |
2008-04-02 |
Cedars Sinai Medical Center |
System and method for expression proteomics based on isotope ratio modification
|
|
US20070087448A1
(en)
*
|
2004-02-16 |
2007-04-19 |
Nelsestuen Gary L |
Biological profiles and methods of use
|
|
TW200538738A
(en)
|
2004-02-20 |
2005-12-01 |
Univ California |
Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
|
|
DE602005023286D1
(de)
*
|
2004-03-31 |
2010-10-14 |
Kazuo Shinya |
Verfahren zum biosubstanzeinfang, zur strukturanalyse oder/und identifizierung unter verwendung einer markierungssubstanz
|
|
US7248360B2
(en)
*
|
2004-04-02 |
2007-07-24 |
Ppd Biomarker Discovery Sciences, Llc |
Polychronic laser scanning system and method of use
|
|
WO2005101017A1
(en)
*
|
2004-04-07 |
2005-10-27 |
Genentech, Inc. |
Mass spectrometry of antibody conjugates
|
|
US20080206737A1
(en)
*
|
2004-05-19 |
2008-08-28 |
Hunter Christie L |
Expression quantification using mass spectrometry
|
|
US20070054345A1
(en)
*
|
2004-05-19 |
2007-03-08 |
Hunter Christie L |
Expression quantification using mass spectrometry
|
|
CA2567459A1
(en)
*
|
2004-05-19 |
2005-12-01 |
Applera Corporation |
Expression quantification using mass spectrometry
|
|
ATE427499T1
(de)
|
2004-05-21 |
2009-04-15 |
Inst Systems Biology |
Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen
|
|
US20080044857A1
(en)
*
|
2004-05-25 |
2008-02-21 |
The Gov Of Usa As Represented By The Secretary Of |
Methods For Making And Using Mass Tag Standards For Quantitative Proteomics
|
|
EP1750126B1
(en)
*
|
2004-05-26 |
2015-09-16 |
Ajinomoto Co., Inc. |
Method and apparatus for analyzing aminofunctional compound
|
|
JP4317083B2
(ja)
|
2004-06-04 |
2009-08-19 |
株式会社日立ハイテクノロジーズ |
質量分析方法及び質量分析システム
|
|
WO2006091214A2
(en)
*
|
2004-06-18 |
2006-08-31 |
Molecular Probes, Inc. |
Fluorescent isotope tags and their method of use
|
|
WO2006017208A1
(en)
*
|
2004-07-12 |
2006-02-16 |
Applera Corporation |
Mass tags for quantitative analyses
|
|
US20070048752A1
(en)
|
2004-07-12 |
2007-03-01 |
Applera Corporation |
Mass tags for quantitative analyses
|
|
DK2299275T3
(en)
|
2004-07-30 |
2018-05-07 |
Adeza Biomedical Corp |
Classification of oncofetal fetronectin level for pregnancy-related indications
|
|
US7592139B2
(en)
*
|
2004-09-24 |
2009-09-22 |
Sandia National Laboratories |
High temperature flow-through device for rapid solubilization and analysis
|
|
JP4563764B2
(ja)
*
|
2004-10-01 |
2010-10-13 |
丸善製薬株式会社 |
ペプチドの定量方法
|
|
WO2006054310A1
(en)
*
|
2004-11-22 |
2006-05-26 |
Biosight Ltd. |
Activated labeling reagents and methods for preparing and using the same
|
|
US20060183238A1
(en)
*
|
2005-02-09 |
2006-08-17 |
Applera Corporation |
Amine-containing compound analysis methods
|
|
US20070037286A1
(en)
*
|
2005-02-09 |
2007-02-15 |
Subhasish Purkayastha |
Thyroxine-containing compound analysis methods
|
|
WO2006096704A2
(en)
|
2005-03-07 |
2006-09-14 |
Invitrogen Corporation |
Isotopically-labeled proteome standards
|
|
US20060251576A1
(en)
*
|
2005-05-03 |
2006-11-09 |
The Regents Of The University Of California |
Methods for measuring cholesterol metabolism and transport
|
|
US10687785B2
(en)
|
2005-05-12 |
2020-06-23 |
The Trustees Of Columbia Univeristy In The City Of New York |
System and method for electromechanical activation of arrhythmias
|
|
DE602005004902T2
(de)
*
|
2005-06-02 |
2008-10-16 |
Entelechon Gmbh |
Künstliches Protein, Verfahren für absolute Quantifizierung der Proteine und seine Benutzung
|
|
JP2006337176A
(ja)
*
|
2005-06-02 |
2006-12-14 |
Eisai R & D Management Co Ltd |
代謝物の定量方法
|
|
TW200711660A
(en)
*
|
2005-06-10 |
2007-04-01 |
Univ California |
Monitoring two dimensions of diabetes pathogenesis separately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development
|
|
EP1754972A1
(en)
|
2005-08-17 |
2007-02-21 |
Agilent Technologies, Inc. |
Folded peptides containing metal binding pockets for protein tagging
|
|
WO2007044935A2
(en)
*
|
2005-10-13 |
2007-04-19 |
Applera Corporation |
Methods for the development of a biomolecule assay
|
|
US7998717B2
(en)
*
|
2005-12-02 |
2011-08-16 |
Pacific Biosciences Of California, Inc. |
Mitigation of photodamage in analytical reactions
|
|
WO2007065273A1
(en)
*
|
2005-12-08 |
2007-06-14 |
The University Of British Columbia |
Mucopolysaccharidosis (mps) diagnostic methods, systems, kits and assays associated therewith
|
|
US20070140967A1
(en)
*
|
2005-12-19 |
2007-06-21 |
Wood Nichole L |
Agents and methods for analyzing protein interactions
|
|
WO2007075910A2
(en)
*
|
2005-12-23 |
2007-07-05 |
Perkinelmer Las, Inc. |
Methods and compositions for detecting enzymatic activity
|
|
US20070148721A1
(en)
*
|
2005-12-28 |
2007-06-28 |
Agilent Technologies, Inc. |
Compositions, methods, systems, and kits for affinity purification
|
|
WO2007078229A1
(en)
*
|
2006-01-05 |
2007-07-12 |
Ge Healthcare Bio-Sciences Ab |
Kit and method for mass labelling
|
|
US20080026480A1
(en)
*
|
2006-02-14 |
2008-01-31 |
Perkinelmer Las, Inc. |
Detection systems for mass labels
|
|
CA2645159A1
(en)
|
2006-03-10 |
2008-06-26 |
Michael S. Urdea |
Multiplex protein fractionation
|
|
CN102943106A
(zh)
*
|
2006-03-13 |
2013-02-27 |
珀金埃尔默健康科学股份有限公司 |
用于质谱法检测的底物和内标
|
|
EP2021492A2
(en)
*
|
2006-04-28 |
2009-02-11 |
Ludwig Institute For Cancer Research |
Quantification of enzyme activity by mass spectrometry
|
|
US20100216657A1
(en)
*
|
2006-05-16 |
2010-08-26 |
Arcxis Biotechnologies, Inc. |
Pcr-free sample preparation and detection systems for high speed biologic analysis and identification
|
|
US8314215B2
(en)
*
|
2006-08-04 |
2012-11-20 |
The Board Of Trustees Of The Leland Stanford Junior University |
Mild chemically cleavable linker system
|
|
US7879799B2
(en)
*
|
2006-08-10 |
2011-02-01 |
Institute For Systems Biology |
Methods for characterizing glycoproteins and generating antibodies for same
|
|
EP1916526A1
(en)
*
|
2006-10-26 |
2008-04-30 |
Koninklijke Philips Electronics N.V. |
Method for diagnostic and therapeutic target discovery by combining isotopic and isobaric labels
|
|
EP1921081A1
(en)
*
|
2006-11-06 |
2008-05-14 |
Koninklijke Philips Electronics N.V. |
Use of arylboronic acids in protein labelling
|
|
KR20120017469A
(ko)
|
2007-01-05 |
2012-02-28 |
유니버시티 오브 취리히 |
질환 특이적 결합 분자 및 표적을 제공하는 방법
|
|
KR100805777B1
(ko)
*
|
2007-02-22 |
2008-02-21 |
한국기초과학지원연구원 |
질량 스펙트럼 데이터 및 １차원 젤에서의 밴드 위치분석을 포함하는 단백질 수식화 분석 시스템 및 이를이용한 단백질 수식화 분석 방법
|
|
WO2008143849A2
(en)
|
2007-05-14 |
2008-11-27 |
Historx, Inc. |
Compartment segregation by pixel characterization using image data clustering
|
|
JP5003274B2
(ja)
*
|
2007-05-16 |
2012-08-15 |
株式会社日立製作所 |
質量分析システムおよび質量分析方法
|
|
WO2008150488A1
(en)
*
|
2007-06-01 |
2008-12-11 |
Laboratory Corporation Of America Holdings |
Methods and systems for quantification of peptides and other analytes
|
|
WO2008156669A1
(en)
|
2007-06-15 |
2008-12-24 |
Historx, Inc. |
Method and system for standardizing microscope instruments
|
|
JP4883540B2
(ja)
*
|
2007-06-21 |
2012-02-22 |
国立大学法人福井大学 |
同位体化合物を標識として使用するタンパク質の分析方法
|
|
EP2015076A1
(en)
*
|
2007-07-11 |
2009-01-14 |
Koninklijke Philips Electronics N.V. |
Protein labelling with tags comprising isotope-coded sub-tags and isobaric sub-tags
|
|
CA2604317C
(en)
|
2007-08-06 |
2017-02-28 |
Historx, Inc. |
Methods and system for validating sample images for quantitative immunoassays
|
|
CA2596204C
(en)
|
2007-08-07 |
2019-02-26 |
Historx, Inc. |
Method and system for determining an optimal dilution of a reagent
|
|
PT2191006E
(pt)
*
|
2007-08-17 |
2013-01-04 |
Univ Washington |
Métodos para ensaiar a actividade enzimática de alfa-liduronidase
|
|
WO2009029810A1
(en)
|
2007-08-31 |
2009-03-05 |
Historx, Inc. |
Automatic exposure time selection for imaging tissue
|
|
JP4921302B2
(ja)
*
|
2007-09-26 |
2012-04-25 |
株式会社日立ハイテクノロジーズ |
質量分析システム
|
|
WO2009061904A2
(en)
*
|
2007-11-06 |
2009-05-14 |
Translational Therapeutics, Inc. |
MASS SPECTROMETRY ASSAY FOR eIF4E AND eIF4E REGULON ACTIVITY
|
|
US8604692B2
(en)
|
2007-11-06 |
2013-12-10 |
Translational Therapeutics, Inc. |
Mass spectrometry assay for eIF4E and eIF4E regulon activity
|
|
US8334506B2
(en)
|
2007-12-10 |
2012-12-18 |
1St Detect Corporation |
End cap voltage control of ion traps
|
|
AU2009223222A1
(en)
|
2008-03-13 |
2009-09-17 |
Perkinelmer Health Sciences, Inc. |
Enzymatic substrates for multiple detection systems
|
|
EP2108957A1
(en)
*
|
2008-04-07 |
2009-10-14 |
Koninklijke Philips Electronics N.V. |
Compounds and methods for the labelling and affinity-selection of proteins
|
|
US7973277B2
(en)
|
2008-05-27 |
2011-07-05 |
1St Detect Corporation |
Driving a mass spectrometer ion trap or mass filter
|
|
WO2009143624A1
(en)
|
2008-05-30 |
2009-12-03 |
The University Of British Columbia |
Methods of diagnosing rejection of a kidney allograft using genomic or proteomic expression profiling
|
|
US20110151494A1
(en)
|
2008-06-30 |
2011-06-23 |
H. Lee Moffit Cancer & Research Institute |
Methods and materials for monitoring myeloma using quantitative mass spectrometry
|
|
WO2010033508A1
(en)
|
2008-09-16 |
2010-03-25 |
Historx, Inc. |
Reproducible quantification of biomarker expression
|
|
US20100081915A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, Alimited Liability Corporation Of The State Of Delaware |
Histological facilitation systems and methods
|
|
US20100081916A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware. |
Histological facilitation systems and methods
|
|
US20100081928A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Histological Facilitation systems and methods
|
|
US20100081924A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Histological facilitation systems and methods
|
|
US20100081927A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Histological facilitation systems and methods
|
|
US20100081926A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Histological facilitation systems and methods
|
|
ES2890501T3
(es)
|
2009-03-02 |
2022-01-20 |
Massachusetts Inst Technology |
Métodos y productos para la creación de perfiles enzimáticos in vivo
|
|
US8227251B2
(en)
*
|
2009-04-14 |
2012-07-24 |
Institute For Systems Biology |
Mass spectrum-based identification and quantitation of proteins and peptides
|
|
WO2010133173A1
(en)
*
|
2009-05-21 |
2010-11-25 |
Rongxiu Li |
Process for differential polypeptides detection and uses thereof
|
|
GB0916881D0
(en)
|
2009-09-25 |
2009-11-11 |
Electrophoretics Ltd |
Mass labels
|
|
EP2309262A1
(en)
|
2009-10-06 |
2011-04-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Method for quantifying biomolecules
|
|
US20110143445A1
(en)
*
|
2009-12-15 |
2011-06-16 |
Dh Technologies Development Pte. Ltd. |
Analysis of Amino Acids And Amine-Containing Compounds Using Tagging Reagents and LC-MS Workflow
|
|
JP2013526840A
(ja)
|
2009-12-21 |
2013-06-27 |
ファーマシーネ，インコーポレイテッド |
組み換えブチリルコリンエステラーゼおよびその切断型
|
|
AU2010341488C1
(en)
*
|
2009-12-22 |
2017-09-28 |
Expression Pathology, Inc. |
Insulin-like growth factor 1 receptor (IGF-1R) protein SRM/MRM assay
|
|
WO2011087869A1
(en)
*
|
2009-12-22 |
2011-07-21 |
Expression Pathology, Inc. |
Secreted protein acidic and rich in cysteine (sparc) protein srm/mrm assay
|
|
US9453845B2
(en)
|
2010-02-01 |
2016-09-27 |
Cell Signaling Technology, Inc. |
Mass spectroscopy analysis of mutant polypeptides in biological samples
|
|
DE102011017084B4
(de)
|
2010-04-14 |
2020-07-09 |
Wisconsin Alumni Research Foundation |
Massenspektrometriedaten-Erfassungsmodus zur Erzielung einer zuverlässigeren Proteinquantifizierung
|
|
EP2588144B1
(en)
|
2010-07-02 |
2018-05-09 |
Ventana Medical Systems, Inc. |
Detecting targets using mass tags and mass spectrometry
|
|
WO2012021733A2
(en)
|
2010-08-12 |
2012-02-16 |
Pacific Biosciences Of California, Inc. |
Photodamage mitigation compounds and systems
|
|
US8742333B2
(en)
|
2010-09-17 |
2014-06-03 |
Wisconsin Alumni Research Foundation |
Method to perform beam-type collision-activated dissociation in the pre-existing ion injection pathway of a mass spectrometer
|
|
CN103547679A
(zh)
*
|
2010-11-24 |
2014-01-29 |
Dh科技发展私人贸易有限公司 |
葡萄糖-6-磷酸脱氢酶的高产量、灵敏检测
|
|
US8492163B2
(en)
|
2011-01-31 |
2013-07-23 |
Dh Technologies Development Pte. Ltd. |
Methods, mixtures, kits and compositions pertaining to analyte determination
|
|
CA2830235C
(en)
|
2011-03-15 |
2023-10-24 |
Massachusetts Institute Of Technology |
Multiplexed detection with isotope-coded reporters
|
|
US9040903B2
(en)
|
2011-04-04 |
2015-05-26 |
Wisconsin Alumni Research Foundation |
Precursor selection using an artificial intelligence algorithm increases proteomic sample coverage and reproducibility
|
|
US9659146B2
(en)
|
2011-05-02 |
2017-05-23 |
Tyler Stuart Bray |
Method for quantitative analysis of complex proteomic data
|
|
WO2012162664A1
(en)
|
2011-05-26 |
2012-11-29 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for opening of a tissue barrier in primates
|
|
WO2013036885A1
(en)
|
2011-09-08 |
2013-03-14 |
The Regents Of The University Of California |
Metabolic flux measurement, imaging and microscopy
|
|
JP6180423B2
(ja)
|
2011-11-08 |
2017-08-16 |
ユニヴァーシティ オブ ワシントン |
リソソーム酵素アッセイ法および組成物
|
|
US20140353486A1
(en)
|
2011-12-07 |
2014-12-04 |
Glaxosmithkline Llc |
Methods for determining total body skeletal muscle mass
|
|
DE102013212179A1
(de)
*
|
2012-07-31 |
2014-02-06 |
Agilent Technologies, Inc. |
Derivatisierung von PNGase F-freigesetzter Glykane auf einem HPLC-Chip
|
|
CN105008393A
(zh)
*
|
2012-12-10 |
2015-10-28 |
弗莱德哈钦森癌症研究中心 |
用于筛选的方法
|
|
US9134319B2
(en)
|
2013-03-15 |
2015-09-15 |
The Regents Of The University Of California |
Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo
|
|
CA2906839A1
(en)
|
2013-03-15 |
2014-09-18 |
Perkinelmer Health Sciences, Inc. |
Compounds and methods relating to testing for lysosomal storage disorders
|
|
CN105431853B
(zh)
|
2013-05-23 |
2018-12-28 |
艾弗诺泰普有限责任公司 |
表型整合的社会研究数据库和方法
|
|
WO2014197754A1
(en)
*
|
2013-06-07 |
2014-12-11 |
Pierce Biotechnology, Inc. |
Absolute quantitation of proteins and protein modifications by mass spectrometry with multiplexed internal standards
|
|
JP6847660B2
(ja)
|
2013-06-07 |
2021-03-24 |
マサチューセッツ インスティテュート オブ テクノロジー |
リガンドをコードする合成バイオマーカーのアフィニティベースの検出
|
|
US20170343540A1
(en)
*
|
2014-12-29 |
2017-11-30 |
Hitachi High-Technologies Corporation |
Analysis method and analysis device
|
|
WO2016178121A1
(en)
|
2015-05-01 |
2016-11-10 |
The University Of British Columbia |
Biomarkers for the detection of acute rejection in heart transplantation
|
|
US10653797B2
(en)
*
|
2015-09-02 |
2020-05-19 |
Sanford Burnham Prebys Medical Discovery Institute |
Compounds and compositions for targeting brain injuries and methods of use thereof
|
|
CN105384785B
(zh)
*
|
2015-11-24 |
2018-06-19 |
中国人民解放军第二军医大学 |
含有半乳糖类脂肪酸衍生物的制备方法及其在医药领域的应用
|
|
EP3398201A4
(en)
*
|
2015-12-31 |
2019-11-06 |
University of Notre Dame du Lac |
ESI-MS VIA AN ELECTRO-KINETICALLY PUMPED INTERFACE
|
|
CN113970589B
(zh)
*
|
2016-01-22 |
2025-04-11 |
普度研究基金会 |
带电质量标记系统
|
|
CN105911101B
(zh)
*
|
2016-04-08 |
2018-09-11 |
中南大学 |
一种简单灵敏的膜性能检测方法
|
|
WO2017177115A1
(en)
|
2016-04-08 |
2017-10-12 |
Massachusetts Institute Of Technology |
Methods to specifically profile protease activity at lymph nodes
|
|
US11428689B2
(en)
|
2016-05-05 |
2022-08-30 |
Massachusetts Institute Of Technology |
Methods and uses for remotely triggered protease activity measurements
|
|
US20190330140A1
(en)
*
|
2016-06-29 |
2019-10-31 |
Hitachi High-Technologies Corporation |
Compound for Use in Enzymatic Reaction and Mass Spectrometry Method
|
|
US11339434B2
(en)
*
|
2016-07-29 |
2022-05-24 |
The Regents Of The University Of California |
Methods for determining gene functions
|
|
DE102017103600A1
(de)
*
|
2017-02-22 |
2018-08-23 |
Eberhard Karls Universität Tübingen Medizinische Fakultät |
Radioaktiv markiertes beta-Galactosidase Substrat für PET Bildgebung der Seneszenz
|
|
CA3059358A1
(en)
|
2017-04-07 |
2018-10-11 |
Massachusetts Institute Of Technology |
Methods to spatially profile protease activity in tissue and sections
|
|
US20200200760A1
(en)
*
|
2017-05-16 |
2020-06-25 |
Lankenau Institute Of Medical Research |
Compositions comprising ligands to rhob protein and the uses thereof
|
|
CN107325154B
(zh)
*
|
2017-06-23 |
2020-11-20 |
广东华肽生物科技有限公司 |
一种具有改善记忆功效的多肽及其分离制备方法和用途
|
|
CN108169397B
(zh)
*
|
2017-11-30 |
2019-11-15 |
中国农业科学院北京畜牧兽医研究所 |
一种相对定量分析肉鸡谷胱甘肽s转移酶gsta2的方法
|
|
JP7028258B2
(ja)
*
|
2018-01-09 |
2022-03-02 |
株式会社島津製作所 |
タンパク質同定方法
|
|
US11054428B2
(en)
|
2018-03-05 |
2021-07-06 |
Massachusetts Institute Of Technology |
Inhalable nanosensors with volatile reporters and uses thereof
|
|
US10656059B2
(en)
|
2018-03-07 |
2020-05-19 |
Alcala Pharmaceutical, Inc. |
Method for qualitative and quantitative multiplexing of drug analytes from biological samples
|
|
RU2678090C1
(ru)
*
|
2018-05-28 |
2019-01-23 |
Федеральное государственное бюджетное научное учреждение "Федеральный научный центр пищевых систем им. В.М. Горбатова" РАН |
Способ подтверждения аутентичности вареных колбасных изделий
|
|
EP3856921B1
(en)
|
2018-09-25 |
2026-04-29 |
Massachusetts Institute Of Technology |
Lung protease nanosensors and uses thereof
|
|
WO2020150560A1
(en)
|
2019-01-17 |
2020-07-23 |
Massachusetts Institute Of Technology |
Sensors for detecting and imaging of cancer metastasis
|
|
US12472448B2
(en)
*
|
2019-01-24 |
2025-11-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compact hydroxamate-based affinity tags for artificially tagging biological macromolecules
|
|
CN110280229B
(zh)
*
|
2019-06-28 |
2022-03-11 |
东南大学 |
喋呤类化合物选择性分离富集材料制备与应用方法
|
|
CA3179460A1
(en)
*
|
2020-06-09 |
2021-12-16 |
Regeneron Pharmaceuticals, Inc. |
A high-throughput and mass-spectrometry-based method for quantitating antibodies
|
|
WO2022081015A1
(en)
|
2020-10-16 |
2022-04-21 |
Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis |
Anti-tumor immunity induces the presentation of aberrant peptides
|
|
ES3006019T3
(en)
*
|
2020-12-17 |
2025-03-17 |
Hoffmann La Roche |
Evaporation-based sample preparation workflow for mass spectrometry
|
|
CN113156002A
(zh)
*
|
2021-04-01 |
2021-07-23 |
河北利德检测技术有限公司 |
一种葡萄糖酸钙中5种有关物质的检测方法
|
|
WO2023080788A1
(en)
|
2021-11-05 |
2023-05-11 |
Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis |
Tryptophan depletion induces production and presentation of tryptophan to phenylalanine substitutions
|
|
WO2024238393A1
(en)
*
|
2023-05-10 |
2024-11-21 |
Northwestern University |
Proteoform imaging and characterization mass spectrometry
|