JP2002161074A5 - - Google Patents
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- Publication number
- JP2002161074A5 JP2002161074A5 JP2001255372A JP2001255372A JP2002161074A5 JP 2002161074 A5 JP2002161074 A5 JP 2002161074A5 JP 2001255372 A JP2001255372 A JP 2001255372A JP 2001255372 A JP2001255372 A JP 2001255372A JP 2002161074 A5 JP2002161074 A5 JP 2002161074A5
- Authority
- JP
- Japan
- Prior art keywords
- neuraminidase
- compound
- label
- sample
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 6
- 102000005348 Neuraminidase Human genes 0.000 claims 5
- 108010006232 Neuraminidase Proteins 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39524595A | 1995-02-27 | 1995-02-27 | |
| US08/476,946 US5866601A (en) | 1995-02-27 | 1995-06-06 | Carbocyclic compounds |
| US58056795A | 1995-12-29 | 1995-12-29 | |
| US08/580,567 | 1995-12-29 | ||
| US08/476,946 | 1995-12-29 | ||
| US08/395,245 | 1995-12-29 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52644296A Division JP3300365B2 (ja) | 1995-02-27 | 1996-02-26 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005207906A Division JP2006036770A (ja) | 1995-02-27 | 2005-07-15 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
| JP2008082197A Division JP2008273948A (ja) | 1995-02-27 | 2008-03-26 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002161074A JP2002161074A (ja) | 2002-06-04 |
| JP2002161074A5 true JP2002161074A5 (enExample) | 2005-10-27 |
| JP4234917B2 JP4234917B2 (ja) | 2009-03-04 |
Family
ID=27410155
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52644296A Expired - Lifetime JP3300365B2 (ja) | 1995-02-27 | 1996-02-26 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
| JP2001255372A Expired - Lifetime JP4234917B2 (ja) | 1995-02-27 | 2001-08-24 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
| JP2005207906A Withdrawn JP2006036770A (ja) | 1995-02-27 | 2005-07-15 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52644296A Expired - Lifetime JP3300365B2 (ja) | 1995-02-27 | 1996-02-26 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005207906A Withdrawn JP2006036770A (ja) | 1995-02-27 | 2005-07-15 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US5952375A (enExample) |
| EP (1) | EP0759917B1 (enExample) |
| JP (3) | JP3300365B2 (enExample) |
| KR (1) | KR100447096B1 (enExample) |
| CN (2) | CN100409844C (enExample) |
| AT (2) | ATE305453T1 (enExample) |
| AU (1) | AU720933B2 (enExample) |
| BR (2) | BR9607098B8 (enExample) |
| CZ (1) | CZ297945B6 (enExample) |
| DE (4) | DE759917T1 (enExample) |
| DK (1) | DK0759917T3 (enExample) |
| ES (2) | ES2118674T3 (enExample) |
| GR (1) | GR3033914T3 (enExample) |
| HU (1) | HU228450B1 (enExample) |
| LU (1) | LU90991I2 (enExample) |
| MX (1) | MX9706496A (enExample) |
| NL (1) | NL300105I2 (enExample) |
| NO (1) | NO318455B1 (enExample) |
| NZ (1) | NZ306625A (enExample) |
| PL (1) | PL194173B1 (enExample) |
| PT (1) | PT759917E (enExample) |
| RU (1) | RU2181357C2 (enExample) |
| SG (1) | SG45864A1 (enExample) |
| SI (1) | SI9620042A (enExample) |
| UA (1) | UA56128C2 (enExample) |
| WO (1) | WO1996026933A1 (enExample) |
Families Citing this family (86)
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| US5714509A (en) * | 1995-05-03 | 1998-02-03 | The University Of Alabama | Inhibitors of bacterial sialidase and methods of making and using the same |
| US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| US6093816A (en) | 1996-06-27 | 2000-07-25 | Isis Pharmaceuticals, Inc. | Cationic lipids |
| US5859284A (en) * | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
| JP3622983B2 (ja) * | 1996-08-23 | 2005-02-23 | ギリアード サイエンシーズ, インコーポレイテッド | シクロヘキセンカルボキシレート誘導体の調製 |
| KR20000052702A (ko) * | 1996-10-21 | 2000-08-25 | 헨슬레이 맥스 디. | 피페리딘 화합물 |
| US5994377A (en) | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
| TR199901081T2 (xx) * | 1996-11-14 | 1999-08-23 | Biota Scientific Management Pty.Ltd. | Y�ntem ve bu y�ntemde kullan�lan yeni bile�imler. |
| US6020344A (en) * | 1997-08-01 | 2000-02-01 | University Of Florida | Enzyme inhibitors and methods of use |
| US5886213A (en) * | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| US20040053999A1 (en) * | 1997-09-17 | 2004-03-18 | Bischofberger Norbert W. | Novel compounds and methods for synthesis and therapy |
| JP2001516739A (ja) * | 1997-09-17 | 2001-10-02 | ギリアード サイエンシーズ, インコーポレイテッド | 6員環を含む化合物、それらの調製プロセス、および医薬としてのそれらの使用 |
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| AU2200199A (en) * | 1997-12-17 | 1999-07-19 | Biocryst Pharmaceuticals, Inc. | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
| US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
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| EP1059283B1 (en) | 1999-06-11 | 2003-05-28 | F. Hoffmann-La Roche Ag | Process for preparing neuraminidase inhibitor ro-64-0796 |
| DE19930177B4 (de) | 1999-06-30 | 2007-02-08 | Nikolai Vladimirovich Bovin | Intermolekular assoziierende Verbindungen und deren Verwendung |
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| US6627396B1 (en) * | 1999-10-28 | 2003-09-30 | The Regents Of The University Of California | Influenza sensor |
| JP2001131144A (ja) | 1999-11-02 | 2001-05-15 | Sagami Chem Res Center | 7−アザビシクロ[4.1.0]ヘプト−3−エン−3−カルボン酸エステル類の製造方法 |
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| DE102011117128A1 (de) | 2011-10-28 | 2013-05-02 | Christian-Albrechts-Universität Zu Kiel | Verbindungen zur Therapie der Influenza |
| RU2469020C1 (ru) * | 2011-11-08 | 2012-12-10 | Александр Васильевич Иващенко | (3r,4r,5s)-5-амино-4-ациламино-3-(1-этил-пропокси)-циклогекс-1-ен-карбоновые кислоты, их эфиры и способ применения |
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| RU2521593C1 (ru) * | 2013-02-27 | 2014-06-27 | Общество с ограниченной ответственностью "Интеллектуальный Диалог" | Моно и дифторзамещенные этил (3r,4r,5s)-5-азидо-4-ацетиламино-3-(1-этилпропокси)-циклогексен-1-карбоксилаты, способ получения и применения |
| JP6453050B2 (ja) * | 2013-11-15 | 2019-01-16 | 国立大学法人富山大学 | 2−デオキシ−2,3−ジデヒドロシアル酸誘導体およびその製造法 |
| CN103819357B (zh) * | 2014-01-28 | 2016-03-16 | 浙江大学 | (-)-有效霉醇叠氮四乙酸酯的制备方法 |
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| GB9410817D0 (en) * | 1994-05-28 | 1994-07-20 | Glaxo Group Ltd | Medicaments |
| AUPM725794A0 (en) * | 1994-08-03 | 1994-08-25 | Biota Scientific Management Pty Ltd | Chemical compounds |
| US5556963A (en) * | 1994-08-05 | 1996-09-17 | Oklahoma Medical Research Foundation | Synthesis of 4-alkoxy-N-acetylneuraminic acid |
| GB9416365D0 (en) * | 1994-08-12 | 1994-10-05 | Glaxo Group Ltd | Medicaments |
| US5512596A (en) * | 1994-09-02 | 1996-04-30 | Gilead Sciences, Inc. | Aromatic compounds |
| WO1996014314A2 (en) | 1994-11-04 | 1996-05-17 | Gilead Sciences, Inc. | Thiepane compounds inhibiting and detecting hiv protease |
| US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
| SI9620042A (sl) * | 1995-02-27 | 1998-12-31 | Gilead Sciences, Inc. | Novi selektivni inhibitorji virusnih ali bakterijskih neuraminidaz |
| US5602277A (en) | 1995-03-30 | 1997-02-11 | Biocryst Pharmaceuticals, Inc. | Substituted benzene derivatives useful as neuraminidase inhibitors |
| US5714509A (en) | 1995-05-03 | 1998-02-03 | The University Of Alabama | Inhibitors of bacterial sialidase and methods of making and using the same |
| GB9525389D0 (en) | 1995-12-12 | 1996-02-14 | Biota Scient Management Ltd | Chemical compounds |
| GB9510141D0 (en) | 1995-05-19 | 1995-07-12 | Biota Scient Management | Chemical compounds |
| JP4162712B2 (ja) * | 1995-05-19 | 2008-10-08 | バイオタ、サイアンティフィック、マネージメント、プロプライエタリ、リミテッド | 6−カルボキサミドジヒドロピラン誘導体 |
| GB9516276D0 (en) * | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
| US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| JP3622983B2 (ja) | 1996-08-23 | 2005-02-23 | ギリアード サイエンシーズ, インコーポレイテッド | シクロヘキセンカルボキシレート誘導体の調製 |
| US5859284A (en) | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| AU711845B2 (en) * | 1996-09-10 | 1999-10-21 | Daikin Industries, Ltd. | 4-substituted-2,7-dideoxy-7-fluoro-2,3-didehydro-sialic acid compounds |
| US5886213A (en) | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
-
1996
- 1996-02-26 SI SI9620042A patent/SI9620042A/sl not_active IP Right Cessation
- 1996-02-26 BR BRPI9607098-6B8D patent/BR9607098B8/pt unknown
- 1996-02-26 BR BR9607098A patent/BR9607098A/pt not_active IP Right Cessation
- 1996-02-26 CN CNB011247142A patent/CN100409844C/zh not_active Expired - Lifetime
- 1996-02-26 DE DE0759917T patent/DE759917T1/de active Pending
- 1996-02-26 KR KR1019970705932A patent/KR100447096B1/ko not_active Expired - Lifetime
- 1996-02-26 SG SG1997004840A patent/SG45864A1/en unknown
- 1996-02-26 RU RU97116714/04A patent/RU2181357C2/ru active
- 1996-02-26 DK DK96912404T patent/DK0759917T3/da active
- 1996-02-26 DE DE2002199052 patent/DE10299052I1/de active Pending
- 1996-02-26 JP JP52644296A patent/JP3300365B2/ja not_active Expired - Lifetime
- 1996-02-26 NZ NZ306625A patent/NZ306625A/xx not_active IP Right Cessation
- 1996-02-26 AT AT99117934T patent/ATE305453T1/de active
- 1996-02-26 HU HU9800026A patent/HU228450B1/hu unknown
- 1996-02-26 US US08/606,624 patent/US5952375A/en not_active Expired - Lifetime
- 1996-02-26 EP EP96912404A patent/EP0759917B1/en not_active Expired - Lifetime
- 1996-02-26 AU AU53571/96A patent/AU720933B2/en not_active Expired
- 1996-02-26 UA UA97094796A patent/UA56128C2/uk unknown
- 1996-02-26 CN CNB961901330A patent/CN1185223C/zh not_active Expired - Lifetime
- 1996-02-26 DE DE69635231T patent/DE69635231T2/de not_active Expired - Lifetime
- 1996-02-26 MX MX9706496A patent/MX9706496A/es unknown
- 1996-02-26 ES ES96912404T patent/ES2118674T3/es not_active Expired - Lifetime
- 1996-02-26 WO PCT/US1996/002882 patent/WO1996026933A1/en not_active Ceased
- 1996-02-26 PL PL96322000A patent/PL194173B1/pl unknown
- 1996-02-26 PT PT96912404T patent/PT759917E/pt unknown
- 1996-02-26 DE DE69607704T patent/DE69607704T2/de not_active Expired - Lifetime
- 1996-02-26 AT AT96912404T patent/ATE191711T1/de active
- 1996-02-26 ES ES99117934T patent/ES2249863T3/es not_active Expired - Lifetime
- 1996-02-26 CZ CZ0269097A patent/CZ297945B6/cs not_active IP Right Cessation
- 1996-05-24 US US08/653,034 patent/US20050176758A1/en not_active Abandoned
-
1997
- 1997-08-26 NO NO19973908A patent/NO318455B1/no not_active IP Right Cessation
-
1999
- 1999-04-08 US US09/288,091 patent/US6225341B1/en not_active Expired - Lifetime
-
2000
- 2000-07-07 GR GR20000401599T patent/GR3033914T3/el unknown
-
2001
- 2001-08-24 JP JP2001255372A patent/JP4234917B2/ja not_active Expired - Lifetime
-
2002
- 2002-10-29 NL NL300105C patent/NL300105I2/nl unknown
- 2002-12-11 LU LU90991C patent/LU90991I2/fr unknown
-
2005
- 2005-07-15 JP JP2005207906A patent/JP2006036770A/ja not_active Withdrawn
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