JP2004510749A5 - - Google Patents
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- Publication number
- JP2004510749A5 JP2004510749A5 JP2002532257A JP2002532257A JP2004510749A5 JP 2004510749 A5 JP2004510749 A5 JP 2004510749A5 JP 2002532257 A JP2002532257 A JP 2002532257A JP 2002532257 A JP2002532257 A JP 2002532257A JP 2004510749 A5 JP2004510749 A5 JP 2004510749A5
- Authority
- JP
- Japan
- Prior art keywords
- agonist
- ppardelta
- activator
- ppar delta
- synthase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108010015181 PPAR delta Proteins 0.000 claims 7
- 239000012190 activator Substances 0.000 claims 5
- 229940122054 Peroxisome proliferator-activated receptor delta agonist Drugs 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 239000003112 inhibitor Substances 0.000 claims 4
- 102000008299 Nitric Oxide Synthase Human genes 0.000 claims 3
- 108010021487 Nitric Oxide Synthase Proteins 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 239000000556 agonist Substances 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- YDBLKRPLXZNVNB-UHFFFAOYSA-N GW 501516 Chemical group CC=1N=C(C=2C=CC(=CC=2)C(F)(F)F)SC=1CSC1=CC=C(OCC(O)=O)C(C)=C1 YDBLKRPLXZNVNB-UHFFFAOYSA-N 0.000 claims 1
- 101000741788 Homo sapiens Peroxisome proliferator-activated receptor alpha Proteins 0.000 claims 1
- 102100038831 Peroxisome proliferator-activated receptor alpha Human genes 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 1
- 125000003831 tetrazolyl group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0024362.6A GB0024362D0 (en) | 2000-10-05 | 2000-10-05 | Medicaments |
| PCT/GB2001/004370 WO2002028433A2 (en) | 2000-10-05 | 2001-10-02 | Use of a ppar delta activator in the treatment of diseases related to no inhibit ion or tnf inhibition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004510749A JP2004510749A (ja) | 2004-04-08 |
| JP2004510749A5 true JP2004510749A5 (enExample) | 2005-12-22 |
Family
ID=9900710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002532257A Pending JP2004510749A (ja) | 2000-10-05 | 2001-10-02 | Ｎｏ阻害またはｔｎｆ阻害に関連した疾病の治療におけるｐｐａｒデルタ活性化因子の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040029938A1 (enExample) |
| EP (1) | EP1324773A2 (enExample) |
| JP (1) | JP2004510749A (enExample) |
| AU (1) | AU2001292044A1 (enExample) |
| GB (1) | GB0024362D0 (enExample) |
| WO (1) | WO2002028433A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL160845A0 (en) | 2001-09-14 | 2004-08-31 | Tularik Inc | Linked biaryl compounds |
| WO2004093910A1 (ja) * | 2003-04-22 | 2004-11-04 | Astellas Pharma Inc. | ＰＰＡＲδアゴニストによる脳神経変性疾患治療剤 |
| PT1638963E (pt) * | 2003-05-20 | 2009-11-18 | Novartis Ag | Heterociclos de azoto n-acilado como ligandos de receptores activados pelo proliferador peroxissomal |
| JP2006527175A (ja) * | 2003-06-06 | 2006-11-30 | エフ．ホフマン−ラ ロシュ アーゲー | アニリン誘導体 |
| CA2530452C (en) | 2003-07-02 | 2011-07-26 | F. Hoffmann-La Roche Ag | Indolyl derivatives substituted with a thiazole ring and their use as ppar modulators |
| JP2007530703A (ja) * | 2004-04-01 | 2007-11-01 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | Ｍｓおよびその他の脱髄疾患を治療するためのペルオキシソーム増殖因子活性化受容体デルタアゴニストの使用 |
| US7126825B2 (en) * | 2004-12-07 | 2006-10-24 | Cleavage Enterprise Co., Ltd. | Combined chip/heat-dissipating metal plate and method for manufacturing the same |
| EP2464349A2 (en) * | 2009-08-14 | 2012-06-20 | Cerenis Therapeutics S.A. | Use of ppar delta ligands for the treatment or prevention of inflammation or energy metabolism/production related diseases |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997028149A1 (en) * | 1996-02-02 | 1997-08-07 | Merck & Co., Inc. | Method for raising hdl cholesterol levels |
| US6300364B1 (en) * | 1997-07-24 | 2001-10-09 | Yamanouchi Pharmaceutical Co., Ltd. | Medicinal compositions with cholesterol-lowering effect |
| GB9914977D0 (en) * | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
| EP1170008A1 (en) * | 2000-07-07 | 2002-01-09 | Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus | Valproic acid and derivatives thereof as histone deacetylase inhibitors |
-
2000
- 2000-10-05 GB GBGB0024362.6A patent/GB0024362D0/en not_active Ceased
-
2001
- 2001-10-02 US US10/398,417 patent/US20040029938A1/en not_active Abandoned
- 2001-10-02 JP JP2002532257A patent/JP2004510749A/ja active Pending
- 2001-10-02 AU AU2001292044A patent/AU2001292044A1/en not_active Abandoned
- 2001-10-02 WO PCT/GB2001/004370 patent/WO2002028433A2/en not_active Ceased
- 2001-10-02 EP EP01972264A patent/EP1324773A2/en not_active Withdrawn