JP2004510750A5 - - Google Patents
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- Publication number
- JP2004510750A5 JP2004510750A5 JP2002532258A JP2002532258A JP2004510750A5 JP 2004510750 A5 JP2004510750 A5 JP 2004510750A5 JP 2002532258 A JP2002532258 A JP 2002532258A JP 2002532258 A JP2002532258 A JP 2002532258A JP 2004510750 A5 JP2004510750 A5 JP 2004510750A5
- Authority
- JP
- Japan
- Prior art keywords
- agonist
- ppardelta
- activator
- ppar delta
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010015181 PPAR delta Proteins 0.000 claims 7
- 239000012190 activator Substances 0.000 claims 5
- 229940122054 Peroxisome proliferator-activated receptor delta agonist Drugs 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 208000027866 inflammatory disease Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 239000000556 agonist Substances 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- YDBLKRPLXZNVNB-UHFFFAOYSA-N GW 501516 Chemical group CC=1N=C(C=2C=CC(=CC=2)C(F)(F)F)SC=1CSC1=CC=C(OCC(O)=O)C(C)=C1 YDBLKRPLXZNVNB-UHFFFAOYSA-N 0.000 claims 1
- 101000741788 Homo sapiens Peroxisome proliferator-activated receptor alpha Proteins 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 102100038831 Peroxisome proliferator-activated receptor alpha Human genes 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 1
- 125000003831 tetrazolyl group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0024361.8A GB0024361D0 (en) | 2000-10-05 | 2000-10-05 | Medicaments |
| PCT/GB2001/004373 WO2002028434A2 (en) | 2000-10-05 | 2001-10-01 | Use of a ppar delta activator for treating inflammatory conditions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004510750A JP2004510750A (ja) | 2004-04-08 |
| JP2004510750A5 true JP2004510750A5 (enExample) | 2005-12-22 |
| JP4106263B2 JP4106263B2 (ja) | 2008-06-25 |
Family
ID=9900709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002532258A Expired - Fee Related JP4106263B2 (ja) | 2000-10-05 | 2001-10-01 | 炎症性の状態の治療のためのｐｐａｒデルタ活性化因子の使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7084161B2 (enExample) |
| EP (1) | EP1324774B1 (enExample) |
| JP (1) | JP4106263B2 (enExample) |
| AT (1) | ATE318615T1 (enExample) |
| AU (1) | AU2001292046A1 (enExample) |
| DE (1) | DE60117584T2 (enExample) |
| ES (1) | ES2259675T3 (enExample) |
| GB (1) | GB0024361D0 (enExample) |
| WO (1) | WO2002028434A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002070011A2 (en) * | 2001-02-02 | 2002-09-12 | Smithkline Beecham Corporation | Treatment of ppar mediated diseases |
| JP2004537525A (ja) * | 2001-06-11 | 2004-12-16 | メルク エンド カムパニー インコーポレーテッド | ＰＰＡＲδアゴニストの投与による炎症性疾患の治療法 |
| NZ531917A (en) | 2001-09-14 | 2006-01-27 | Japan Tobacco Inc | Linked biaryl compounds |
| FR2836829B1 (fr) * | 2002-03-11 | 2005-11-25 | Bio Merieux | Utilisation de l-alpha-lysophosphatidylcholine pour obtenir la differenciation de monocytes en cellules dendritiques matures in vitro |
| RU2006138495A (ru) * | 2004-04-01 | 2008-05-10 | Авентис Фармасьютикалз Инк. (Us) | Использование агонистов рецепторов, активируемых пролифератором пероксисомы дельта для лечения рс и других демиелинизирующих заболеваний |
| US8053598B2 (en) | 2004-05-05 | 2011-11-08 | High Point Pharmaceuticals, Llc | Compounds, their preparation and use |
| ATE486055T1 (de) | 2004-05-05 | 2010-11-15 | High Point Pharmaceuticals Llc | Neue verbindungen, ihre herstellung und verwendung |
| US7544702B2 (en) | 2004-08-12 | 2009-06-09 | Amgen Inc. | Bisaryl-sulfonamides |
| JP5052511B2 (ja) | 2005-06-30 | 2012-10-17 | ハイ ポイント ファーマシューティカルズ，エルエルシー | Ｐｐａｒデルタ活性化因子としてのフェノキシ酢酸 |
| CA2631390C (en) | 2005-12-22 | 2014-03-11 | Per Sauerberg | Phenoxy acetic acids as ppar delta activators |
| JP2009529512A (ja) | 2006-03-09 | 2009-08-20 | ハイ ポイント ファーマシューティカルズ，リミティド ライアビリティ カンパニー | 新規な化合物、それらの製造法、及び使用法 |
| US20080004281A1 (en) * | 2006-06-28 | 2008-01-03 | Kalypsys, Inc. | Methods for the modulation of crp by the selective modulation of ppar delta |
| WO2008143254A1 (ja) * | 2007-05-21 | 2008-11-27 | Senju Pharmaceutical Co., Ltd. | ＰＰＡＲδアゴニスト含有医薬 |
| KR20120099378A (ko) * | 2009-08-14 | 2012-09-10 | 닛뽕 케미파 가부시키가이샤 | 염증 또는 에너지 대사/생산 관련 질환의 치료 또는 예방을 위한 ｐｐａｒ 델타 리간드의 용도 |
| KR102038866B1 (ko) * | 2012-12-24 | 2019-10-31 | 서울대학교산학협력단 | ＰＰＡＲδ 활성물질의 항생제, 화상 및 창상 치료제, 당뇨성 족부궤양 치료제로서의 용도 |
| EP3043789B1 (en) | 2013-09-09 | 2020-07-08 | vTv Therapeutics LLC | Use of a ppar-delta agonists for treating muscle atrophy |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
| KR102750722B1 (ko) * | 2022-03-16 | 2025-01-09 | 재단법인 대구경북첨단의료산업진흥재단 | 싸이아다이아졸 화합물 및 이를 포함하는 염증성 질환의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997028149A1 (en) * | 1996-02-02 | 1997-08-07 | Merck & Co., Inc. | Method for raising hdl cholesterol levels |
| US6300364B1 (en) * | 1997-07-24 | 2001-10-09 | Yamanouchi Pharmaceutical Co., Ltd. | Medicinal compositions with cholesterol-lowering effect |
| GB9914977D0 (en) | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
-
2000
- 2000-10-05 GB GBGB0024361.8A patent/GB0024361D0/en not_active Ceased
-
2001
- 2001-10-01 JP JP2002532258A patent/JP4106263B2/ja not_active Expired - Fee Related
- 2001-10-01 US US10/398,629 patent/US7084161B2/en not_active Expired - Fee Related
- 2001-10-01 ES ES01972266T patent/ES2259675T3/es not_active Expired - Lifetime
- 2001-10-01 WO PCT/GB2001/004373 patent/WO2002028434A2/en not_active Ceased
- 2001-10-01 AU AU2001292046A patent/AU2001292046A1/en not_active Abandoned
- 2001-10-01 EP EP01972266A patent/EP1324774B1/en not_active Expired - Lifetime
- 2001-10-01 DE DE60117584T patent/DE60117584T2/de not_active Expired - Fee Related
- 2001-10-01 AT AT01972266T patent/ATE318615T1/de not_active IP Right Cessation
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