RU95113474A - Применение 2-амино-6-н-пропиламино-4,5,6,7-тетрагидробензотиазола, его энантиомеров и фармакологически переносимых кислотноаддитивных солей в качестве антидепрессанта и фармацевтическая композиция с антидепрессивной активностью на их основе - Google Patents
Применение 2-амино-6-н-пропиламино-4,5,6,7-тетрагидробензотиазола, его энантиомеров и фармакологически переносимых кислотноаддитивных солей в качестве антидепрессанта и фармацевтическая композиция с антидепрессивной активностью на их основеInfo
- Publication number
- RU95113474A RU95113474A RU95113474/14A RU95113474A RU95113474A RU 95113474 A RU95113474 A RU 95113474A RU 95113474/14 A RU95113474/14 A RU 95113474/14A RU 95113474 A RU95113474 A RU 95113474A RU 95113474 A RU95113474 A RU 95113474A
- Authority
- RU
- Russia
- Prior art keywords
- propylamino
- amino
- salts
- tetraghydrobenzenesothesis
- rescency
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title claims 3
- 239000011780 sodium chloride Substances 0.000 title claims 3
- FASDKYOPVNHBLU-UHFFFAOYSA-N 6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine Chemical compound C1C(NCCC)CCC2=C1SC(N)=N2 FASDKYOPVNHBLU-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 230000001430 anti-depressive Effects 0.000 claims 2
- 239000000935 antidepressant agent Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- DRRYZHHKWSHHFT-UHFFFAOYSA-N NC(CC1)Cc2c1nc(N)[s]2 Chemical compound NC(CC1)Cc2c1nc(N)[s]2 DRRYZHHKWSHHFT-UHFFFAOYSA-N 0.000 description 1
Claims (2)
2. Фармацевтическая композиция с антидепрессивной активностью, содержащая активное вещество и по крайней мере один физиологически переносимый носитель, отличающаяся тем, что в качестве активного вещества она содержит 2-амино-6-н-пропиламино-4,5,6,7-тетрагидробензотиазол формулы
в виде рацемата или обоих энантиомеров или фармакологически переносимых кислотно-аддитивных солей в эффективном количестве.
в виде рацемата или обоих энантиомеров или фармакологически переносимых кислотно-аддитивных солей в эффективном количестве.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4241013A DE4241013A1 (de) | 1992-12-05 | 1992-12-05 | Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung |
DEP4241013.4 | 1992-12-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU95113474A true RU95113474A (ru) | 1997-07-27 |
RU2157685C2 RU2157685C2 (ru) | 2000-10-20 |
Family
ID=6474503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU95113474/14A RU2157685C2 (ru) | 1992-12-05 | 1993-12-02 | Фармацевтическая композиция с антидепрессивной активностью |
Country Status (29)
Country | Link |
---|---|
US (1) | US6191153B1 (ru) |
EP (1) | EP0675717B1 (ru) |
JP (1) | JP3221880B2 (ru) |
KR (1) | KR100311165B1 (ru) |
CN (1) | CN1052400C (ru) |
AT (1) | ATE183091T1 (ru) |
AU (1) | AU674378B2 (ru) |
BG (1) | BG62475B1 (ru) |
CA (1) | CA2150131C (ru) |
CZ (1) | CZ282679B6 (ru) |
DE (2) | DE4241013A1 (ru) |
DK (1) | DK0675717T3 (ru) |
ES (1) | ES2136725T3 (ru) |
FI (1) | FI952734A0 (ru) |
GR (1) | GR3031521T3 (ru) |
HK (1) | HK1019003A1 (ru) |
HU (1) | HU221014B1 (ru) |
IL (1) | IL107870A (ru) |
MX (1) | MX9307644A (ru) |
NO (1) | NO306930B1 (ru) |
NZ (1) | NZ258876A (ru) |
PL (1) | PL309282A1 (ru) |
RU (1) | RU2157685C2 (ru) |
SG (1) | SG49228A1 (ru) |
SK (1) | SK281441B6 (ru) |
TW (1) | TW362973B (ru) |
UA (1) | UA35604C2 (ru) |
WO (1) | WO1994013287A1 (ru) |
ZA (1) | ZA939065B (ru) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6156777A (en) | 1994-12-15 | 2000-12-05 | Pharmacia & Upjohn Company | Use of pramipexole as a neuroprotective agent |
US5650420A (en) * | 1994-12-15 | 1997-07-22 | Pharmacia & Upjohn Company | Pramipexole as a neuroprotective agent |
US6001861A (en) * | 1998-01-16 | 1999-12-14 | Pharmacia & Upjohn Company | Use of pramipexole in the treatment of restless legs syndrome |
DE19830201A1 (de) * | 1998-07-07 | 2000-01-13 | Boehringer Ingelheim Pharma | Mittel mit antidepressiver Wirkung |
WO2000006162A1 (de) * | 1998-07-27 | 2000-02-10 | Boehringer Ingelheim Pharma Kg | Mittel mit antidepressiver wirkung, mit pramipexol und einem weiteren antidepressivum |
PE20011074A1 (es) | 2000-02-23 | 2001-10-04 | Upjohn Co | Uso de pramipexol en el tratamiento de trastornos de adiccion |
EP1303502A2 (en) * | 2000-07-06 | 2003-04-23 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Tetrahydrobenzothiazole analogues as neuroprotective agents |
US20020165246A1 (en) * | 2001-03-05 | 2002-11-07 | Andrew Holman | Administration of sleep restorative agents |
EP1260221A3 (en) * | 2001-05-23 | 2002-12-18 | Pfizer Products Inc. | Combination treatment for depression and anxiety |
DE10138275A1 (de) * | 2001-08-10 | 2003-02-27 | Boehringer Ingelheim Pharma | Verbindungen zur Beseitigung der Anhedonie |
MY142204A (en) * | 2002-07-25 | 2010-10-29 | Pharmacia Corp | Pramipexole once-daily dosage form |
DE102004006808A1 (de) * | 2004-02-11 | 2005-09-01 | Grünenthal GmbH | Substituierte 4,5,6,7-Tetrahydro-benzothiazol-2-ylamin-Verbindungen |
EP1781260B2 (en) * | 2004-08-13 | 2014-04-02 | Boehringer Ingelheim International GmbH | Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof |
MX2007001850A (es) * | 2004-08-13 | 2007-03-28 | Boehringer Ingelheim Int | Formulacion de pildora de liberacion prolongada que contiene pramipexol o una sal farmaceuticamente aceptable del mismo, metodo para fabricarlo y uso del mismo. |
ZA200708445B (en) * | 2005-04-04 | 2009-03-25 | Takeda Pharmaceutical | Preventive or remedy for depression or anxiety neurosis |
EP1940398A1 (de) * | 2005-10-18 | 2008-07-09 | Boehringer Ingelheim International GmbH | Verwendung von pramipexol zur behandlung des moderaten bis schweren restless legs syndroms (rls) |
WO2007090883A1 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Extended release formulation |
US20090041844A1 (en) * | 2006-02-10 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Modified Release Formulation |
US11160809B2 (en) * | 2017-04-10 | 2021-11-02 | Chase Therapeutics Corporation | NK1-antagonist combination and method for treating synucleinopathies |
BR112019028034A2 (pt) | 2017-06-30 | 2020-07-07 | Chase Therapeutics Corporation | composições de antagonista de nk-1 e métodos para uso no tratamento da depressão |
CN108802584B (zh) * | 2018-06-29 | 2020-12-08 | 广东工业大学 | 一种变压器绝缘纸老化状态评估方法 |
TWI672472B (zh) * | 2018-08-15 | 2019-09-21 | 鄭映芳 | 飲料製冰機裝置 |
CN110028464B (zh) * | 2019-04-26 | 2022-11-18 | 浙江海洋大学 | 一种南极真菌次级代谢衍生物BTZ-one及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE45735T1 (de) * | 1984-12-22 | 1989-09-15 | Thomae Gmbh Dr K | Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arnzneimittel. |
DE3843227A1 (de) * | 1988-12-22 | 1990-07-05 | Boehringer Ingelheim Kg | Neue verwendung von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzthiazol |
DE3930282A1 (de) * | 1989-09-11 | 1991-03-21 | Boehringer Ingelheim Kg | Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit |
-
1992
- 1992-12-05 DE DE4241013A patent/DE4241013A1/de not_active Withdrawn
-
1993
- 1993-12-02 KR KR1019950702272A patent/KR100311165B1/ko not_active IP Right Cessation
- 1993-12-02 WO PCT/EP1993/003389 patent/WO1994013287A1/de active IP Right Grant
- 1993-12-02 SG SG1996007972A patent/SG49228A1/en unknown
- 1993-12-02 AU AU57152/94A patent/AU674378B2/en not_active Expired
- 1993-12-02 SK SK740-95A patent/SK281441B6/sk not_active IP Right Cessation
- 1993-12-02 DK DK94902661T patent/DK0675717T3/da active
- 1993-12-02 HU HU9501623A patent/HU221014B1/hu unknown
- 1993-12-02 DE DE59309733T patent/DE59309733D1/de not_active Expired - Lifetime
- 1993-12-02 ES ES94902661T patent/ES2136725T3/es not_active Expired - Lifetime
- 1993-12-02 JP JP51374394A patent/JP3221880B2/ja not_active Expired - Lifetime
- 1993-12-02 NZ NZ258876A patent/NZ258876A/en not_active IP Right Cessation
- 1993-12-02 CZ CZ951440A patent/CZ282679B6/cs not_active IP Right Cessation
- 1993-12-02 EP EP94902661A patent/EP0675717B1/de not_active Expired - Lifetime
- 1993-12-02 AT AT94902661T patent/ATE183091T1/de active
- 1993-12-02 PL PL93309282A patent/PL309282A1/xx unknown
- 1993-12-02 RU RU95113474/14A patent/RU2157685C2/ru active
- 1993-12-02 CA CA002150131A patent/CA2150131C/en not_active Expired - Lifetime
- 1993-12-02 UA UA95063059A patent/UA35604C2/ru unknown
- 1993-12-03 ZA ZA939065A patent/ZA939065B/xx unknown
- 1993-12-03 IL IL10787093A patent/IL107870A/en not_active IP Right Cessation
- 1993-12-03 MX MX9307644A patent/MX9307644A/es unknown
- 1993-12-04 CN CN93120080A patent/CN1052400C/zh not_active Expired - Lifetime
- 1993-12-13 TW TW082110542A patent/TW362973B/zh not_active IP Right Cessation
-
1995
- 1995-06-02 NO NO952207A patent/NO306930B1/no not_active IP Right Cessation
- 1995-06-05 BG BG99700A patent/BG62475B1/bg unknown
- 1995-06-05 FI FI952734A patent/FI952734A0/fi unknown
-
1998
- 1998-12-14 HK HK98113329A patent/HK1019003A1/xx not_active IP Right Cessation
-
1999
- 1999-10-13 GR GR990402617T patent/GR3031521T3/el unknown
-
2000
- 2000-03-15 US US09/526,079 patent/US6191153B1/en not_active Expired - Lifetime
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