ES2136725T3 - Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo. - Google Patents

Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo.

Info

Publication number
ES2136725T3
ES2136725T3 ES94902661T ES94902661T ES2136725T3 ES 2136725 T3 ES2136725 T3 ES 2136725T3 ES 94902661 T ES94902661 T ES 94902661T ES 94902661 T ES94902661 T ES 94902661T ES 2136725 T3 ES2136725 T3 ES 2136725T3
Authority
ES
Spain
Prior art keywords
amino
pramipexol
tetrahidrobenzotiazole
propil
antidepressive effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94902661T
Other languages
English (en)
Inventor
Rudolf Hammer
Joachim Mierau
Erich Lehr
Franco Borsini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BOEHRINGER INGELHEIM PHARMA
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
BOEHRINGER INGELHEIM PHARMA
Boehringer Ingelheim Pharma GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BOEHRINGER INGELHEIM PHARMA, Boehringer Ingelheim Pharma GmbH and Co KG filed Critical BOEHRINGER INGELHEIM PHARMA
Application granted granted Critical
Publication of ES2136725T3 publication Critical patent/ES2136725T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA INVENCION SE REFIERE A LA UTILIZACION DE PRAMIPEXOL COMO MEDICAMENTO CON EFECTO ANTIDEPRESIVO.
ES94902661T 1992-12-05 1993-12-02 Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo. Expired - Lifetime ES2136725T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4241013A DE4241013A1 (de) 1992-12-05 1992-12-05 Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
PCT/EP1993/003389 WO1994013287A1 (de) 1992-12-05 1993-12-02 Verwendung von 2-amino-6-a-propyl-amino-4,5,6,7-tetrahydrobenzothiazol (pramipexol) als arzneimittel mit antidepressiver wirkung

Publications (1)

Publication Number Publication Date
ES2136725T3 true ES2136725T3 (es) 1999-12-01

Family

ID=6474503

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94902661T Expired - Lifetime ES2136725T3 (es) 1992-12-05 1993-12-02 Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo.

Country Status (29)

Country Link
US (1) US6191153B1 (es)
EP (1) EP0675717B1 (es)
JP (1) JP3221880B2 (es)
KR (1) KR100311165B1 (es)
CN (1) CN1052400C (es)
AT (1) ATE183091T1 (es)
AU (1) AU674378B2 (es)
BG (1) BG62475B1 (es)
CA (1) CA2150131C (es)
CZ (1) CZ282679B6 (es)
DE (2) DE4241013A1 (es)
DK (1) DK0675717T3 (es)
ES (1) ES2136725T3 (es)
FI (1) FI952734A0 (es)
GR (1) GR3031521T3 (es)
HK (1) HK1019003A1 (es)
HU (1) HU221014B1 (es)
IL (1) IL107870A (es)
MX (1) MX9307644A (es)
NO (1) NO306930B1 (es)
NZ (1) NZ258876A (es)
PL (1) PL309282A1 (es)
RU (1) RU2157685C2 (es)
SG (1) SG49228A1 (es)
SK (1) SK281441B6 (es)
TW (1) TW362973B (es)
UA (1) UA35604C2 (es)
WO (1) WO1994013287A1 (es)
ZA (1) ZA939065B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156777A (en) 1994-12-15 2000-12-05 Pharmacia & Upjohn Company Use of pramipexole as a neuroprotective agent
US5650420A (en) * 1994-12-15 1997-07-22 Pharmacia & Upjohn Company Pramipexole as a neuroprotective agent
US6001861A (en) 1998-01-16 1999-12-14 Pharmacia & Upjohn Company Use of pramipexole in the treatment of restless legs syndrome
DE19830201A1 (de) * 1998-07-07 2000-01-13 Boehringer Ingelheim Pharma Mittel mit antidepressiver Wirkung
CA2301899C (en) * 1998-07-27 2008-11-18 Boehringer Ingelheim Pharma Kg Agent with an antidepressant activity
PE20011074A1 (es) 2000-02-23 2001-10-04 Upjohn Co Uso de pramipexol en el tratamiento de trastornos de adiccion
EP1303502A2 (en) * 2000-07-06 2003-04-23 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Tetrahydrobenzothiazole analogues as neuroprotective agents
WO2002069974A1 (en) * 2001-03-05 2002-09-12 Andrew Holman Administration of sleep restorative agents
EP1260221A3 (en) * 2001-05-23 2002-12-18 Pfizer Products Inc. Combination treatment for depression and anxiety
DE10138275A1 (de) * 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
PA8578501A1 (es) * 2002-07-25 2005-02-04 Pharmacia Corp Forma de dosificacion una vez al dia de pramipexol
DE102004006808A1 (de) * 2004-02-11 2005-09-01 Grünenthal GmbH Substituierte 4,5,6,7-Tetrahydro-benzothiazol-2-ylamin-Verbindungen
PT1781260E (pt) * 2004-08-13 2010-12-20 Boehringer Ingelheim Int Formulação em comprimido de libertação prolongada contendo pramipexole ou um seu sal farmaceuticamente aceitável, um método para a preparação do mesmo e sua utilização
CA2576386A1 (en) * 2004-08-13 2006-02-16 Boehringer Ingelheim International Gmbh Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
JP5259181B2 (ja) * 2005-04-04 2013-08-07 武田薬品工業株式会社 うつ病または不安神経症の予防または治療剤
CA2626249A1 (en) * 2005-10-18 2007-04-26 Boehringer Ingelheim International Gmbh Use of pramipexol for treating moderate to severe restless legs syndrome (rls)
JP2009526021A (ja) * 2006-02-10 2009-07-16 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 放出を加減した製剤
US20090098202A1 (en) * 2006-02-10 2009-04-16 Boehringer Ingelheim International Gmbh Extended Release Formulation
JP7271437B2 (ja) * 2017-04-10 2023-05-11 チェイス セラピューティクス コーポレイション Ｎｋ１拮抗薬組み合わせおよびシヌクレイノパチーを治療する方法
US11266633B2 (en) 2017-06-30 2022-03-08 Chase Therapeutics Corporation NK-1 antagonist compositions and methods for use in treating depression
CN108802584B (zh) * 2018-06-29 2020-12-08 广东工业大学 一种变压器绝缘纸老化状态评估方法
TWI672472B (zh) * 2018-08-15 2019-09-21 鄭映芳 飲料製冰機裝置
CN110028464B (zh) * 2019-04-26 2022-11-18 浙江海洋大学 一种南极真菌次级代谢衍生物BTZ-one及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186087B1 (de) * 1984-12-22 1989-08-23 Dr. Karl Thomae GmbH Tetrahydro-benzthiazole, deren Herstellung und deren Verwendung als Zwischenprodukte oder als Arnzneimittel
DE3843227A1 (de) * 1988-12-22 1990-07-05 Boehringer Ingelheim Kg Neue verwendung von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzthiazol
DE3930282A1 (de) * 1989-09-11 1991-03-21 Boehringer Ingelheim Kg Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit

Also Published As

Publication number Publication date
DE4241013A1 (de) 1994-06-09
UA35604C2 (uk) 2001-04-16
HU221014B1 (hu) 2002-07-29
NO306930B1 (no) 2000-01-17
AU5715294A (en) 1994-07-04
FI952734A (fi) 1995-06-05
HUT71798A (en) 1996-02-28
CZ144095A3 (en) 1996-03-13
KR100311165B1 (ko) 2001-12-28
WO1994013287A1 (de) 1994-06-23
KR950703953A (ko) 1995-11-17
BG62475B1 (bg) 1999-12-30
SG49228A1 (en) 1998-05-18
CA2150131A1 (en) 1994-06-23
ATE183091T1 (de) 1999-08-15
HK1019003A1 (en) 2000-01-14
MX9307644A (es) 1994-06-30
GR3031521T3 (en) 2000-01-31
DK0675717T3 (da) 2000-02-28
US6191153B1 (en) 2001-02-20
CN1052400C (zh) 2000-05-17
CZ282679B6 (cs) 1997-08-13
EP0675717B1 (de) 1999-08-11
IL107870A0 (en) 1994-04-12
CA2150131C (en) 2004-09-21
DE59309733D1 (de) 1999-09-16
NZ258876A (en) 1997-07-27
FI952734A0 (fi) 1995-06-05
PL309282A1 (en) 1995-10-02
RU2157685C2 (ru) 2000-10-20
JPH08504201A (ja) 1996-05-07
IL107870A (en) 1996-12-05
NO952207D0 (no) 1995-06-02
AU674378B2 (en) 1996-12-19
SK74095A3 (en) 1996-05-08
BG99700A (bg) 1996-04-30
NO952207L (no) 1995-06-02
JP3221880B2 (ja) 2001-10-22
TW362973B (en) 1999-07-01
EP0675717A1 (de) 1995-10-11
ZA939065B (en) 1994-08-04
HU9501623D0 (en) 1995-08-28
CN1091635A (zh) 1994-09-07
SK281441B6 (sk) 2001-03-12

Similar Documents

Publication Publication Date Title
ES2136725T3 (es) Utilizacion de 2-amino-6-n-propil-amino-4,5,6,7-tetrahidrobenzotiazol (pramipexol) como medicamento con efecto antidepresivo.
SV1995000042A (es) Heteroaril-oxazolidinonas de 5 eslabones ref. le a 30523-sv
PT750618E (pt) Derivados de oxazolidinona e composicoes farmaceuticas que os contem
ES2172937T3 (es) 21-hidroxi-6,19-oxidoprogesterona(21oh-6op) como medicamento para tratar el exceso de glucocorticoides.
ES2173858T3 (es) Analogos de huperzina a.
ES2195040T3 (es) Conjugado que incluye un principio activo, un polipeptido y varios polieteres y su uso como medicamento.
FR2398067A1 (fr) Nouvelles 4-pyrones substituees en positions 2, 3 et 6 et medicament les contenant
AR059965A2 (es) Uso de 8,9-dehidroestrona para la preparacion de un medicamento antioxidante
ES2118248T3 (es) Esteres y amidas de 9-cloro-prostaglandina y su empleo para preparar medicamentos.
PT1000067E (pt) Tiazolobenzo-heterociclos sua preparacao e medicamentos que os contem
CL2004000486A1 (es) Compuestos de (piridinil amino)-bencisoxazol y bencisotiazol substituidos, la composicion farmaceutica que los contiene, su procedimiento de preparacion a partir de un bencisoxazol o bencisotiazol y su uso como farmaco con actividad antidepresiva.
PT1001942E (pt) Poli-hidroxibutilpirazinas sua preparacao e medicamentos que as contem
IL85560A0 (en) Pharmaceutical compositions containing an antidepressant and a synergist
PT986390E (pt) Composicoes farmaceuticas que contem cicloridrato de cinchonina
PT932408E (pt) FORMULACOES FARMACEUTICAS E COSMéTICAS COM ACTIVIDADES ANTIMICROBIANA
ES2103218B1 (es) Derivados de piridona azetidinil substituidos con actividad antimicrobiana.
FR2398070A1 (fr) Nouvelles 1-piperazinyl-triazolo-thieno-1,4-diazepines substituees et leur application comme medicaments
FR2390421A1 (fr) 1-acyl-2-hydroxy-1,3-diaminopropanes a titre de nouveaux medicaments
IT8020075A0 (it) Composto ad attivita'psicostimolante e antidepressiva, processo per la sua preparazione e composizioni farmaceutiche relative.
ES2179668T3 (es) Un compuesto wf002, su produccion y su uso.
UA31266A (uk) Лікувальний засіб "дінальгін"
FR2368950A1 (fr) Agents anticoccidiens et ovo-larvicides renfermant un amino-alcane
IT8719351A0 (it) Composti ad attivita'epatoprotettrice e mucolitica, procedimento per la loro preparazione e composizioni farmaceutiche relative.
IT8919283A0 (it) Composizione farmaceutica comprendente come ingrediente attivo 3 n piperidinometil azino metilrifamicina s.
FI853194A0 (fi) Foerfarande foer framstaellnig av farmakologiskt aktiva 2,5,5,8a-tetrametyl-1,2,3,4,4a,5,6,7,8,8a -dekahydronaftalen-1-spiro-2'-(2',3'-dihydrobensofuran)-derivat.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 675717

Country of ref document: ES