HU228450B1 - Novel selective inhibitors of viral or bacterial neuraminidases - Google Patents

Novel selective inhibitors of viral or bacterial neuraminidases Download PDF

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Publication number
HU228450B1
HU228450B1 HU9800026A HUP9800026A HU228450B1 HU 228450 B1 HU228450 B1 HU 228450B1 HU 9800026 A HU9800026 A HU 9800026A HU P9800026 A HUP9800026 A HU P9800026A HU 228450 B1 HU228450 B1 HU 228450B1
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HU
Hungary
Prior art keywords
mmol
solution
compound
water
mixture
Prior art date
Application number
HU9800026A
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English (en)
Hungarian (hu)
Inventor
Norbert W Bischofberger
Choung U Kim
Willard Lew
Hongtao Liu
Matthew A Williams
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27410155&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU228450(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/476,946 external-priority patent/US5866601A/en
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of HUP9800026A2 publication Critical patent/HUP9800026A2/hu
Publication of HUP9800026A3 publication Critical patent/HUP9800026A3/hu
Publication of HU228450B1 publication Critical patent/HU228450B1/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
HU9800026A 1995-02-27 1996-02-26 Novel selective inhibitors of viral or bacterial neuraminidases HU228450B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39524595A 1995-02-27 1995-02-27
US08/476,946 US5866601A (en) 1995-02-27 1995-06-06 Carbocyclic compounds
US58056795A 1995-12-29 1995-12-29
PCT/US1996/002882 WO1996026933A1 (en) 1995-02-27 1996-02-26 Novel selective inhibitors of viral or bacterial neuraminidases

Publications (3)

Publication Number Publication Date
HUP9800026A2 HUP9800026A2 (hu) 1999-09-28
HUP9800026A3 HUP9800026A3 (en) 2002-04-29
HU228450B1 true HU228450B1 (en) 2013-03-28

Family

ID=27410155

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800026A HU228450B1 (en) 1995-02-27 1996-02-26 Novel selective inhibitors of viral or bacterial neuraminidases

Country Status (26)

Country Link
US (3) US5952375A (enExample)
EP (1) EP0759917B1 (enExample)
JP (3) JP3300365B2 (enExample)
KR (1) KR100447096B1 (enExample)
CN (2) CN1185223C (enExample)
AT (2) ATE191711T1 (enExample)
AU (1) AU720933B2 (enExample)
BR (2) BR9607098A (enExample)
CZ (1) CZ297945B6 (enExample)
DE (4) DE69607704T2 (enExample)
DK (1) DK0759917T3 (enExample)
ES (2) ES2249863T3 (enExample)
GR (1) GR3033914T3 (enExample)
HU (1) HU228450B1 (enExample)
LU (1) LU90991I2 (enExample)
MX (1) MX9706496A (enExample)
NL (1) NL300105I2 (enExample)
NO (1) NO318455B1 (enExample)
NZ (1) NZ306625A (enExample)
PL (1) PL194173B1 (enExample)
PT (1) PT759917E (enExample)
RU (1) RU2181357C2 (enExample)
SG (1) SG45864A1 (enExample)
SI (1) SI9620042A (enExample)
UA (1) UA56128C2 (enExample)
WO (1) WO1996026933A1 (enExample)

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CN100409844C (zh) 2008-08-13
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ES2118674T1 (es) 1998-10-01
PT759917E (pt) 2000-10-31
HK1026893A1 (en) 2000-12-29
JP3300365B2 (ja) 2002-07-08
ES2249863T3 (es) 2006-04-01
CN1347693A (zh) 2002-05-08
SI9620042A (sl) 1998-12-31
NO318455B1 (no) 2005-03-21
US5952375A (en) 1999-09-14
CN1185223C (zh) 2005-01-19
EP0759917A1 (en) 1997-03-05
JP4234917B2 (ja) 2009-03-04
PL194173B1 (pl) 2007-05-31
HUP9800026A2 (hu) 1999-09-28
BR9607098B8 (pt) 2014-11-18
CZ297945B6 (cs) 2007-05-02
NL300105I2 (nl) 2003-02-03
DE69607704D1 (de) 2000-05-18
HUP9800026A3 (en) 2002-04-29
DE759917T1 (de) 1998-10-22
US20050176758A1 (en) 2005-08-11
RU2181357C2 (ru) 2002-04-20
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SG45864A1 (en) 1999-04-27
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DE69635231T2 (de) 2006-07-13
WO1996026933A1 (en) 1996-09-06
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US6225341B1 (en) 2001-05-01
ATE191711T1 (de) 2000-04-15
NO973908L (no) 1997-10-27
CN1147813A (zh) 1997-04-16
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