ITMI20011726A0 - Forme polimorfe della lercanidipina cloridrato - Google Patents

Forme polimorfe della lercanidipina cloridrato

Info

Publication number
ITMI20011726A0
ITMI20011726A0 IT2001MI001726A ITMI20011726A ITMI20011726A0 IT MI20011726 A0 ITMI20011726 A0 IT MI20011726A0 IT 2001MI001726 A IT2001MI001726 A IT 2001MI001726A IT MI20011726 A ITMI20011726 A IT MI20011726A IT MI20011726 A0 ITMI20011726 A0 IT MI20011726A0
Authority
IT
Italy
Prior art keywords
polymorphic forms
lercanidipine hydrochloride
lercanidipine
hydrochloride
polymorphic
Prior art date
Application number
IT2001MI001726A
Other languages
English (en)
Inventor
Fausto Bonifacio
Amedeo Leonardi
Francesco Campana
Iasi Gianluca De
Original Assignee
Recordati Ind Chimica E Farma
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11448245&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ITMI20011726(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati Ind Chimica E Farma, Recordati Chem Pharm filed Critical Recordati Ind Chimica E Farma
Priority to IT2001MI001726A priority Critical patent/ITMI20011726A1/it
Publication of ITMI20011726A0 publication Critical patent/ITMI20011726A0/it
Priority to CA 2380202 priority patent/CA2380202A1/en
Priority to UA2004031657A priority patent/UA82988C2/uk
Priority to ARP020102958A priority patent/AR037139A1/es
Priority to KR1020057006786A priority patent/KR20050043992A/ko
Priority to CNB028154134A priority patent/CN100448847C/zh
Priority to PT05106264T priority patent/PT1600441E/pt
Priority to DE60234961T priority patent/DE60234961D1/de
Priority to PL369522A priority patent/PL216066B1/pl
Priority to JP2003519034A priority patent/JP2005504045A/ja
Priority to MEP-2008-29A priority patent/ME01525B/me
Priority to MEP-29/08A priority patent/MEP2908A/xx
Priority to SI200231065T priority patent/SI2157083T1/sl
Priority to EP08019093A priority patent/EP2036890A1/en
Priority to DE60206787T priority patent/DE60206787T2/de
Priority to PT91746099T priority patent/PT2157083E/pt
Priority to EP02762428A priority patent/EP1432683B9/en
Priority to AT05106264T priority patent/ATE453624T1/de
Priority to APAP/P/2004/002989A priority patent/AP1766A/en
Priority to SI200230871T priority patent/SI1600441T1/sl
Priority to PCT/EP2002/008699 priority patent/WO2003014084A1/en
Priority to AU2002327924A priority patent/AU2002327924C1/en
Priority to NZ531558A priority patent/NZ531558A/en
Priority to NZ541341A priority patent/NZ541341A/en
Priority to MXPA04001069A priority patent/MXPA04001069A/es
Priority to KR1020057021508A priority patent/KR100626819B1/ko
Priority to ES02762428T priority patent/ES2212759T3/es
Priority to OA1200400033A priority patent/OA12648A/en
Priority to YU11304A priority patent/RS52161B/en
Priority to EA200400280A priority patent/EA005673B1/ru
Priority to ES05106264T priority patent/ES2334678T3/es
Priority to BR0211739-8A priority patent/BR0211739A/pt
Priority to SI200230250T priority patent/SI1432683T1/sl
Priority to ES09174609.9T priority patent/ES2555213T3/es
Priority to KR1020047001558A priority patent/KR100667687B1/ko
Priority to IL15391702A priority patent/IL153917A/xx
Priority to EP05106264A priority patent/EP1600441B1/en
Priority to DK02762428T priority patent/DK1432683T3/da
Priority to IL16464802A priority patent/IL164648A0/xx
Priority to HU0401163A priority patent/HU229563B1/hu
Priority to AT02762428T priority patent/ATE307114T1/de
Priority to EP09174609.9A priority patent/EP2157083B1/en
Priority to DK09174609.9T priority patent/DK2157083T3/en
Priority to DK05106264.4T priority patent/DK1600441T3/da
Priority to CN2008101812364A priority patent/CN101475524B/zh
Priority to CA 2399583 priority patent/CA2399583A1/en
Priority to US10/214,385 priority patent/US20030069285A1/en
Priority to UY27410A priority patent/UY27410A1/es
Priority to US10/214,386 priority patent/US6852737B2/en
Priority to PE2002000715A priority patent/PE20030328A1/es
Priority to CA2399459A priority patent/CA2399459C/en
Publication of ITMI20011726A1 publication Critical patent/ITMI20011726A1/it
Priority to NO20040266A priority patent/NO325541B1/no
Priority to TNP2004000024A priority patent/TNSN04024A1/en
Priority to EC2004004973A priority patent/ECSP044973A/es
Priority to MA27517A priority patent/MA27133A1/fr
Priority to HR20040156A priority patent/HRP20040156B1/xx
Priority to US10/782,376 priority patent/US20040204459A1/en
Priority to ZA2004/01806A priority patent/ZA200401806B/en
Priority to IL164648A priority patent/IL164648A/en
Priority to HK04110181A priority patent/HK1067123A1/xx
Priority to US11/048,647 priority patent/US20050239847A1/en
Priority to US11/048,646 priority patent/US20050192323A1/en
Priority to HK06106196.3A priority patent/HK1086263A1/xx
Priority to HK10106911.1A priority patent/HK1140487A1/xx
Priority to NO20082330A priority patent/NO335651B1/no
Priority to CY20101100011T priority patent/CY1109711T1/el
Priority to CY20151101129T priority patent/CY1117051T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
IT2001MI001726A 2001-08-06 2001-08-06 Forme polimorfe della lercanidipina cloridrato ITMI20011726A1 (it)

Priority Applications (67)

Application Number Priority Date Filing Date Title
IT2001MI001726A ITMI20011726A1 (it) 2001-08-06 2001-08-06 Forme polimorfe della lercanidipina cloridrato
CA 2380202 CA2380202A1 (en) 2001-08-06 2002-04-03 Novel crude and crystalline forms of lercanidipine hydrochloride
UA2004031657A UA82988C2 (uk) 2001-08-06 2002-05-08 Поліморфні кристалічні форми гідрохлориду лерканідипіну та спосіб їх одержання
ARP020102958A AR037139A1 (es) 2001-08-06 2002-08-02 Formas crudas a y b de 1,1-trimetil-n-(3,3-difenil-propil)2-aminoetil-1,4-dihidro-2,6-dimetil-4-(3-nitrofenil)piridin-3,5 dicarboxilato, formas cristalinas (i) y (ii) obtenidas a partir de dichas formas crudas y composiciones farmaceuticas antihipertensivas que contienen por lo menos una de dichas f
KR1020057006786A KR20050043992A (ko) 2001-08-06 2002-08-05 레르카니디핀 염산의 신규 결정성 다형 및 그 제조방법
CNB028154134A CN100448847C (zh) 2001-08-06 2002-08-05 新的盐酸乐卡地平结晶多晶形物及其制备方法
PT05106264T PT1600441E (pt) 2001-08-06 2002-08-05 Forma cristalina de cloridrato de lercanidipina para utilização como agente anti-hipertensor
DE60234961T DE60234961D1 (de) 2001-08-06 2002-08-05 Kristallform von Lercanipidin-Hydrochlorid zur Verwendung als antihypertensives Mittel
PL369522A PL216066B1 (pl) 2001-08-06 2002-08-05 Solwaty chlorowodorku lerkanidypiny, sposoby ich wytwarzania, krystaliczna postac (II) chlorowodorku lerkanidypiny, sposoby jej wytwarzania, kompozycja farmaceutyczna ja zawierajaca, jednostkowa postac dawkowania, zastosowanie krystalicznej postaci (I) chlorowodorku lerkanidypiny oraz sposób jej wytwarzania
JP2003519034A JP2005504045A (ja) 2001-08-06 2002-08-05 塩酸レルカニジピンの新規な原形および結晶性形状
MEP-2008-29A ME01525B (me) 2001-08-06 2002-08-05 Novi kristalni polimorfni oblici lerkanidipin hidrohlorida i postupak za njihovo dobijanje
MEP-29/08A MEP2908A (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
SI200231065T SI2157083T1 (sl) 2001-08-06 2002-08-05 Farmacevtske sestave, vsebujoče kristalno obliko (i) lerkanidipin hidroklorida
EP08019093A EP2036890A1 (en) 2001-08-06 2002-08-05 Crystalline form (i) of lercanidipine hydrochloride
DE60206787T DE60206787T2 (de) 2001-08-06 2002-08-05 Kristalline polymorphe formen von lercanidipin hydrochlorid und verfahren zu deren herstellung
PT91746099T PT2157083E (pt) 2001-08-06 2002-08-05 Composições farmacêuticas contendo a forma (i) cristalina de cloridrato de lercanidipina
EP02762428A EP1432683B9 (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and processes for their preparation
AT05106264T ATE453624T1 (de) 2001-08-06 2002-08-05 Kristallform von lercanipidin-hydrochlorid zur verwendung als antihypertensives mittel
APAP/P/2004/002989A AP1766A (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation.
SI200230871T SI1600441T1 (sl) 2001-08-06 2002-08-05 Kristalna oblika lerkanidipin hidroklorida za uporabo kot sredstvo proti hipertenziji
PCT/EP2002/008699 WO2003014084A1 (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
AU2002327924A AU2002327924C1 (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
NZ531558A NZ531558A (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
NZ541341A NZ541341A (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
MXPA04001069A MXPA04001069A (es) 2001-08-06 2002-08-05 Nuevas formas polimorficas cristalinas de clorhidrato de lercanidipina y proceso para su preparacion.
KR1020057021508A KR100626819B1 (ko) 2001-08-06 2002-08-05 레르카니디핀 염산의 신규 결정성 다형 및 그 제조방법
ES02762428T ES2212759T3 (es) 2001-08-06 2002-08-05 Nuevas formas polimorfas cristalinas de hidrocloruro de lercanidipino y procedimientos para su preparacion.
OA1200400033A OA12648A (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation.
YU11304A RS52161B (en) 2001-08-06 2002-08-05 NEW CRYSTAL POLYMORPHIC FORMS OF LERCANIDIPINE HYDROCHLORIDE AND A PROCEDURE FOR OBTAINING THEM
EA200400280A EA005673B1 (ru) 2001-08-06 2002-08-05 Новые неочищенные и кристаллические формы гидрохлорида лерканидипина
ES05106264T ES2334678T3 (es) 2001-08-06 2002-08-05 Nueva foprma cristalina de hidrocloruro de lercanidipino y procedimiento para su preparacion.
BR0211739-8A BR0211739A (pt) 2001-08-06 2002-08-05 Novas formas polimórficas cristalinas de cloridrato de lercanidipina e processo para preparação das mesmas
SI200230250T SI1432683T1 (sl) 2001-08-06 2002-08-05 Nove kristalne polimorfne oblike lerkanidipina inpostopki za njihovo pripravo
ES09174609.9T ES2555213T3 (es) 2001-08-06 2002-08-05 Composiciones farmacéuticas que contienen la forma cristalina (I) del clorhidrato de lercanidipino
KR1020047001558A KR100667687B1 (ko) 2001-08-06 2002-08-05 레르카니디핀 염산의 신규 결정성 다형 및 그 제조방법
IL15391702A IL153917A (en) 2001-08-06 2002-08-05 Crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
EP05106264A EP1600441B1 (en) 2001-08-06 2002-08-05 Crystal form of lercanidipine hydrochloride for use as an antihypertensive agent
DK02762428T DK1432683T3 (da) 2001-08-06 2002-08-05 Hidtil ukendte krystallinske polymorfe former af lercanidipinhydrochlorid og fremgangsmåder til fremstilling heraf
IL16464802A IL164648A0 (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
HU0401163A HU229563B1 (en) 2001-08-06 2002-08-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation and pharmaceutical compositions containing the crystalline forms
AT02762428T ATE307114T1 (de) 2001-08-06 2002-08-05 Kristalline polymorphe formen von lercanidipin hydrochlorid und verfahren zu deren herstellung
EP09174609.9A EP2157083B1 (en) 2001-08-06 2002-08-05 Pharmaceutical compositions containing crystalline form (I) of lercanidipine hydrochloride
DK09174609.9T DK2157083T3 (en) 2001-08-06 2002-08-05 Pharmaceutical compositions containing the crystalline form (I) of lercanidipine hydrochloride
DK05106264.4T DK1600441T3 (da) 2001-08-06 2002-08-05 Krystallinsk form af elrcanidipinhydrochlorid til anvendelse som et antihypertensivt middel
CN2008101812364A CN101475524B (zh) 2001-08-06 2002-08-05 盐酸乐卡地平结晶多晶形物及其制备方法
CA 2399583 CA2399583A1 (en) 2001-08-06 2002-08-06 Novel solvate and crystalline forms of lercanidipine hydrochloride
US10/214,385 US20030069285A1 (en) 2001-08-06 2002-08-06 Novel solvate and crystalline forms of lercanidipine hydrochloride
UY27410A UY27410A1 (es) 2001-08-06 2002-08-06 Formas novedosas crudas cristalinas
US10/214,386 US6852737B2 (en) 2001-08-06 2002-08-06 Crude and crystalline forms of lercanidipine hydrochloride
PE2002000715A PE20030328A1 (es) 2001-08-06 2002-08-06 Formas novedosas, crudas y cristalinas de clorhidrato de lercanidipina
CA2399459A CA2399459C (en) 2001-08-06 2002-08-06 Novel crude and crystalline forms of lercanidipine hydrochloride
NO20040266A NO325541B1 (no) 2001-08-06 2004-01-20 Nye krystallinske polymorfe former av lerkanidipinhydroklorid og fremgangsmate for fremstilling derav
TNP2004000024A TNSN04024A1 (en) 2001-08-06 2004-02-05 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
EC2004004973A ECSP044973A (es) 2001-08-06 2004-02-06 Nuevas formas polimorficas cristalinas de clorhidrato de lercanidipina y proceso para su preparacion
MA27517A MA27133A1 (fr) 2001-08-06 2004-02-06 Nouvelles formes polymorphes cristallines d'hydrochlorure de lercanidipine et procede de fabrication associe
HR20040156A HRP20040156B1 (en) 2001-08-06 2004-02-18 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
US10/782,376 US20040204459A1 (en) 2001-08-06 2004-02-18 Novel crude and crystalline forms of lercanidipine hydrochloride
ZA2004/01806A ZA200401806B (en) 2001-08-06 2004-03-04 Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
IL164648A IL164648A (en) 2001-08-06 2004-10-17 Crystalline forms of recanidipine hydrochloride, a process for their formation and pharmaceutical preparations containing them
HK04110181A HK1067123A1 (en) 2001-08-06 2004-12-23 Novel crystalline polymorphic forms of lercanidipine hydrochloride and processes for their preparation
US11/048,647 US20050239847A1 (en) 2001-08-06 2005-01-31 Novel crude and crystalline forms of lercanidipine hydrochloride
US11/048,646 US20050192323A1 (en) 2001-08-06 2005-01-31 Novel crude and crystalline forms of lercanidipine hydrochloride
HK06106196.3A HK1086263A1 (en) 2001-08-06 2006-05-29 Crystal form of lercanidipine hydrochloride for use as an antihypertensive agent
HK10106911.1A HK1140487A1 (en) 2001-08-06 2006-05-29 Pharmaceutical compositions containing crystalline form (i) of lercanidipine hydrochloride (i)
NO20082330A NO335651B1 (no) 2001-08-06 2008-05-22 Nye krystallinske polymorfe former av lerkanidipinhydroklorid og fremgangsmåte for fremstilling derav
CY20101100011T CY1109711T1 (el) 2001-08-06 2010-01-05 Νεα κρυσταλλικη μορφη υδροχλωριουχου λερκανιδιπινης και διαδικασιες για την παρασκευη τους
CY20151101129T CY1117051T1 (el) 2001-08-06 2015-12-10 Φαρμακευτικες συνθεσεις που περιεχουν κρυσταλλικη μορφη (i) της υδροχλωριουχου λερκανιδιπινης

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001MI001726A ITMI20011726A1 (it) 2001-08-06 2001-08-06 Forme polimorfe della lercanidipina cloridrato

Publications (2)

Publication Number Publication Date
ITMI20011726A0 true ITMI20011726A0 (it) 2001-08-06
ITMI20011726A1 ITMI20011726A1 (it) 2003-02-06

Family

ID=11448245

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2001MI001726A ITMI20011726A1 (it) 2001-08-06 2001-08-06 Forme polimorfe della lercanidipina cloridrato

Country Status (36)

Country Link
EP (4) EP2036890A1 (it)
JP (1) JP2005504045A (it)
KR (3) KR100626819B1 (it)
CN (2) CN100448847C (it)
AP (1) AP1766A (it)
AR (1) AR037139A1 (it)
AT (2) ATE307114T1 (it)
AU (1) AU2002327924C1 (it)
BR (1) BR0211739A (it)
CY (2) CY1109711T1 (it)
DE (2) DE60206787T2 (it)
DK (3) DK2157083T3 (it)
EA (1) EA005673B1 (it)
EC (1) ECSP044973A (it)
ES (3) ES2212759T3 (it)
HK (3) HK1067123A1 (it)
HR (1) HRP20040156B1 (it)
HU (1) HU229563B1 (it)
IL (3) IL164648A0 (it)
IT (1) ITMI20011726A1 (it)
MA (1) MA27133A1 (it)
ME (2) MEP2908A (it)
MX (1) MXPA04001069A (it)
NO (2) NO325541B1 (it)
NZ (2) NZ541341A (it)
OA (1) OA12648A (it)
PE (1) PE20030328A1 (it)
PL (1) PL216066B1 (it)
PT (2) PT2157083E (it)
RS (1) RS52161B (it)
SI (3) SI1600441T1 (it)
TN (1) TNSN04024A1 (it)
UA (1) UA82988C2 (it)
UY (1) UY27410A1 (it)
WO (1) WO2003014084A1 (it)
ZA (1) ZA200401806B (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20011726A1 (it) 2001-08-06 2003-02-06 Recordati Ind Chimica E Farma Forme polimorfe della lercanidipina cloridrato
AR043395A1 (es) * 2003-02-28 2005-07-27 Recordati Ireland Ltd Terapia de combinacion para la hipertension utilizando lercanidipina y un bloqueante de los receptores de angiotensina ii
CA2547657A1 (en) * 2003-12-01 2005-06-16 Lifecycle Pharma A/S Pharmaceutical compositions comprising lercanidipine
AR052918A1 (es) 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
KR20080048065A (ko) 2005-09-16 2008-05-30 그렌마크 파머수티칼스 엘티디. 다형 형태의 염산 레르카니디핀 및 이것의 제조방법
KR100821165B1 (ko) * 2006-03-10 2008-04-14 동우신테크 주식회사 레르카니디핀 염산염의 제조 방법
JP2010514753A (ja) * 2006-12-29 2010-05-06 ドンウ シンテック カンパニー リミテッド レルカニジピン塩酸塩の製造方法
EP2121575A2 (en) * 2007-03-05 2009-11-25 Actavis Group PTC EHF Lercanidipine hydrochloride polymorphs and an improved process for preparation of 1,1,n-trimethyl-n-(3,3-diphenylpropyl)-2-aminoethyl acetoacetate
WO2011161223A2 (en) 2010-06-23 2011-12-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts
EP2444394A1 (en) 2010-10-21 2012-04-25 Alembic Pharmaceuticals Limited Process for the preparation of amorphous form of lercanidipine HCI
EP2654729B1 (en) 2010-12-24 2016-05-04 KRKA, d.d., Novo mesto Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts together with an organic acid
EP2700632A4 (en) * 2011-04-18 2014-09-03 Hefei Beini Medical Technology Company Ltd METHOD FOR CLEANING DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS AND PRODUCING NANOPARTICLES THEREFOR
CN102558032B (zh) * 2011-12-16 2014-02-26 华润赛科药业有限责任公司 一种无定形盐酸乐卡地平及其制备方法
CN102531999B (zh) * 2011-12-16 2014-02-26 华润赛科药业有限责任公司 无定形盐酸乐卡地平及其制备方法
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