IS2123B - Indól-2,3-díon-3-oxíms afleiður - Google Patents
Indól-2,3-díon-3-oxíms afleiðurInfo
- Publication number
- IS2123B IS2123B IS4748A IS4748A IS2123B IS 2123 B IS2123 B IS 2123B IS 4748 A IS4748 A IS 4748A IS 4748 A IS4748 A IS 4748A IS 2123 B IS2123 B IS 2123B
- Authority
- IS
- Iceland
- Prior art keywords
- dione
- het
- oxime derivatives
- indole
- ring
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK106996 | 1996-10-01 | ||
| DK127796 | 1996-11-13 | ||
| PCT/DK1997/000418 WO1998014447A1 (en) | 1996-10-01 | 1997-10-01 | Novel indole-2,3-dione-3-oxime derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IS4748A IS4748A (is) | 1998-05-18 |
| IS2123B true IS2123B (is) | 2006-07-14 |
Family
ID=26065167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS4748A IS2123B (is) | 1996-10-01 | 1998-05-18 | Indól-2,3-díon-3-oxíms afleiður |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | USRE38200E1 (cs) |
| EP (1) | EP0869958B1 (cs) |
| JP (1) | JP3319762B2 (cs) |
| KR (1) | KR100492052B1 (cs) |
| CN (1) | CN1093859C (cs) |
| AT (1) | ATE286052T1 (cs) |
| AU (1) | AU716435B2 (cs) |
| BG (1) | BG63874B1 (cs) |
| BR (1) | BR9706765A (cs) |
| CA (1) | CA2238410C (cs) |
| CZ (1) | CZ297938B6 (cs) |
| DE (1) | DE69732090T2 (cs) |
| DK (1) | DK0869958T3 (cs) |
| EE (1) | EE9800144A (cs) |
| ES (1) | ES2235253T3 (cs) |
| HK (1) | HK1017682A1 (cs) |
| HU (1) | HU225145B1 (cs) |
| IL (1) | IL124563A (cs) |
| IS (1) | IS2123B (cs) |
| NO (1) | NO310722B1 (cs) |
| NZ (1) | NZ330456A (cs) |
| PL (1) | PL193041B1 (cs) |
| PT (1) | PT869958E (cs) |
| RU (1) | RU2190612C2 (cs) |
| SI (1) | SI0869958T1 (cs) |
| SK (1) | SK282729B6 (cs) |
| TR (1) | TR199800956T1 (cs) |
| UA (1) | UA54403C2 (cs) |
| WO (1) | WO1998014447A1 (cs) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| NZ507259A (en) * | 1998-03-31 | 2003-07-25 | Neurosearch As | Indole-2,3-dione-3-oxime derivatives for therapeutic use |
| AU4910500A (en) * | 1999-05-19 | 2000-12-12 | Neurosearch A/S | Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders |
| CN1298704C (zh) * | 2000-01-24 | 2007-02-07 | 神经研究公司 | 具有神经营养活性的靛红衍生物 |
| IT1318636B1 (it) * | 2000-07-21 | 2003-08-27 | Roberto Pellicciari | Derivati dell'acido 2- o 3- tenoico ad attivita' antagonista deirecettori del glutammato. |
| JP2004523543A (ja) * | 2001-02-15 | 2004-08-05 | ニューロサーチ、アクティーゼルスカブ | 神経栄養活性を有する化合物とドパミン活性を増加させる化合物の組み合わせ作用によるパーキンソン病の治療法 |
| CA2452610A1 (en) | 2001-07-13 | 2003-01-23 | Pharmacia & Upjohn Company | Hexahydroazepino (4, 5-g) indoles and indolines as 5-ht receptor ligands |
| DE60303825T2 (de) * | 2002-08-22 | 2006-08-17 | Neurosearch A/S | Verfahren zum herstellen von enantiomeren von indol-2,3-dion-3-oxim-derivaten |
| GB0507298D0 (en) | 2005-04-11 | 2005-05-18 | Novartis Ag | Organic compounds |
| CN101346375B (zh) * | 2005-11-23 | 2013-04-10 | 阿罗斯药物有限责任公司 | 调节门离子通道用组合物和方法 |
| WO2007115403A1 (en) * | 2006-04-10 | 2007-10-18 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| EP2010529A1 (en) * | 2006-04-10 | 2009-01-07 | PainCeptor Pharma Corp. | Compositions and methods for modulating gated ion channels |
| US20100041691A1 (en) * | 2006-09-12 | 2010-02-18 | Neurosearch A/S | Pharmaceutical compositions comprising combinations of an ampa/kainate antagonistic compound and an inhibitor of a multidrug resistance protein |
| US20080108622A1 (en) * | 2006-10-19 | 2008-05-08 | Eisenach James C | Combination therapy for the treatment of pain |
| US20080108603A1 (en) * | 2006-10-19 | 2008-05-08 | Eisenach James C | Combination therapy for the treatment of pain |
| WO2010104324A2 (ko) * | 2009-03-10 | 2010-09-16 | 한국과학기술연구원 | 베타-아밀로이드 집적체 및 피브릴에 우수한 결합 친화도를 가지는 할로겐화 이소인돌론 화합물, 및 이의 제조 방법 및 용도 |
| CN102653538A (zh) * | 2011-03-04 | 2012-09-05 | 爱斯医药科技(南京)有限公司 | Spd-502的制备方法 |
| EP3288935B1 (en) * | 2015-04-29 | 2019-10-30 | Janssen Pharmaceutica NV | Indolone compounds and their use as ampa receptor modulators |
| SI3288940T1 (sl) | 2015-04-29 | 2021-07-30 | Janssen Pharmaceutica Nv | Azabenzimidazoli in njihova uporaba kot modulatorji AMPA-receptorja |
| EP3288945B1 (en) | 2015-04-29 | 2019-09-18 | Janssen Pharmaceutica NV | Imidazopyrazines and pyrazolopyrimidines and their use as ampa receptor modulators |
| CA2984290C (en) | 2015-04-29 | 2022-03-01 | Janssen Pharmaceutica Nv | Benzimidazolone and benzothiazolone compounds and their use as ampa receptor modulators |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9204914A (es) * | 1991-08-28 | 1993-07-01 | Frank Watjen | Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende. |
| US5721230A (en) | 1993-05-10 | 1998-02-24 | Hoffmann-La Roche Inc. | Substituted pyrroles |
| ES2111930T3 (es) * | 1993-05-13 | 1998-03-16 | Neurosearch As | Antagonistas del acido amp y procedimientos de tratamiento con la ayuda de estos. |
| DK81593D0 (da) * | 1993-07-07 | 1993-07-07 | Neurosearch As | Nye isatinoximderivater, deres fremstilling og anvendelse |
| NZ293265A (en) * | 1994-09-14 | 1998-01-26 | Neurosearch As | 5-aryl-isoquinoline-2-one-3-acyloxime derivatives fused with a n-heterocyclic ring |
| US5801174A (en) * | 1994-09-14 | 1998-09-01 | Neurosearch A/S | Fused indole and quinoxaline derivatives, their preparation and use |
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
-
1997
- 1997-01-10 UA UA98052752A patent/UA54403C2/uk unknown
- 1997-10-01 KR KR10-1998-0704103A patent/KR100492052B1/ko not_active IP Right Cessation
- 1997-10-01 NZ NZ330456A patent/NZ330456A/en unknown
- 1997-10-01 IL IL12456397A patent/IL124563A/xx not_active IP Right Cessation
- 1997-10-01 US US09/956,892 patent/USRE38200E1/en not_active Expired - Fee Related
- 1997-10-01 SI SI9730698T patent/SI0869958T1/xx unknown
- 1997-10-01 CA CA002238410A patent/CA2238410C/en not_active Expired - Fee Related
- 1997-10-01 PT PT97941880T patent/PT869958E/pt unknown
- 1997-10-01 CZ CZ0160698A patent/CZ297938B6/cs not_active IP Right Cessation
- 1997-10-01 TR TR1998/00956T patent/TR199800956T1/xx unknown
- 1997-10-01 US US09/077,554 patent/US6124285A/en not_active Expired - Lifetime
- 1997-10-01 JP JP51615898A patent/JP3319762B2/ja not_active Expired - Fee Related
- 1997-10-01 PL PL327073A patent/PL193041B1/pl not_active IP Right Cessation
- 1997-10-01 HU HU9901630A patent/HU225145B1/hu not_active IP Right Cessation
- 1997-10-01 CN CN97191602A patent/CN1093859C/zh not_active Expired - Fee Related
- 1997-10-01 WO PCT/DK1997/000418 patent/WO1998014447A1/en active IP Right Grant
- 1997-10-01 ES ES97941880T patent/ES2235253T3/es not_active Expired - Lifetime
- 1997-10-01 DK DK97941880T patent/DK0869958T3/da active
- 1997-10-01 EP EP97941880A patent/EP0869958B1/en not_active Expired - Lifetime
- 1997-10-01 AU AU43768/97A patent/AU716435B2/en not_active Ceased
- 1997-10-01 SK SK676-98A patent/SK282729B6/sk not_active IP Right Cessation
- 1997-10-01 DE DE69732090T patent/DE69732090T2/de not_active Expired - Lifetime
- 1997-10-01 BR BR9706765-2A patent/BR9706765A/pt not_active Application Discontinuation
- 1997-10-01 RU RU98112237/04A patent/RU2190612C2/ru not_active IP Right Cessation
- 1997-10-01 EE EE9800144A patent/EE9800144A/xx unknown
- 1997-10-01 AT AT97941880T patent/ATE286052T1/de not_active IP Right Cessation
-
1998
- 1998-05-18 IS IS4748A patent/IS2123B/xx unknown
- 1998-05-26 BG BG102489A patent/BG63874B1/bg unknown
- 1998-05-29 NO NO19982466A patent/NO310722B1/no not_active IP Right Cessation
-
1999
- 1999-06-30 HK HK99102769A patent/HK1017682A1/xx not_active IP Right Cessation
-
2000
- 2000-05-31 US US09/584,117 patent/US6693111B1/en not_active Expired - Fee Related
Also Published As
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