IN2012DN00377A - - Google Patents
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- Publication number
- IN2012DN00377A IN2012DN00377A IN377DEN2012A IN2012DN00377A IN 2012DN00377 A IN2012DN00377 A IN 2012DN00377A IN 377DEN2012 A IN377DEN2012 A IN 377DEN2012A IN 2012DN00377 A IN2012DN00377 A IN 2012DN00377A
- Authority
- IN
- India
- Prior art keywords
- glucagon
- activity
- peptides
- glp
- abstract
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18757809P | 2009-06-16 | 2009-06-16 | |
PCT/US2010/038825 WO2010148089A1 (en) | 2009-06-16 | 2010-06-16 | Gip receptor-active glucagon compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN00377A true IN2012DN00377A (de) | 2015-08-21 |
Family
ID=43356738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN377DEN2012 IN2012DN00377A (de) | 2009-06-16 | 2010-06-16 |
Country Status (18)
Country | Link |
---|---|
US (2) | US9150632B2 (de) |
EP (1) | EP2443146B1 (de) |
JP (1) | JP5887265B2 (de) |
KR (1) | KR20120087875A (de) |
CN (1) | CN102459325B (de) |
AU (1) | AU2010260058B2 (de) |
BR (1) | BRPI1014508A2 (de) |
CA (1) | CA2765026A1 (de) |
CL (1) | CL2011003173A1 (de) |
HK (1) | HK1169998A1 (de) |
IL (1) | IL216881A (de) |
IN (1) | IN2012DN00377A (de) |
MX (1) | MX2011013625A (de) |
PE (1) | PE20120914A1 (de) |
RU (1) | RU2012101274A (de) |
SG (1) | SG176858A1 (de) |
TW (1) | TWI549687B (de) |
WO (1) | WO2010148089A1 (de) |
Families Citing this family (98)
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CN101534846B (zh) | 2005-11-07 | 2014-11-05 | 印第安纳大学研究及科技有限公司 | 显示生理学溶解性和稳定性的胰高血糖素类似物 |
EP2124974B1 (de) | 2007-01-05 | 2017-03-15 | Indiana University Research and Technology Corporation | Glocagonanaloga mit erhöhter löslichkeit in physiologischen ph-puffern |
AU2008216265B2 (en) | 2007-02-15 | 2014-04-03 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
ES2558155T3 (es) | 2007-10-30 | 2016-02-02 | Indiana University Research And Technology Corporation | Compuestos que muestran actividad antagonista de glucacón y agonista de GLP-1 |
CA2707861A1 (en) | 2007-10-30 | 2009-05-07 | Indiana University Research And Technology Corporation | Glucagon antagonists |
TWI541023B (zh) | 2008-06-17 | 2016-07-11 | 印第安納大學科技研究公司 | 在生理ph緩衝液中呈現增強之溶解度及穩定性之升糖激素類似物 |
EA020326B9 (ru) | 2008-06-17 | 2015-03-31 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Агонисты смешанного действия на основе глюкозозависимого инсулинотропного пептида для лечения нарушений обмена веществ и ожирения |
CL2009001424A1 (es) | 2008-06-17 | 2010-04-30 | Univ Indiana Res & Tech Corp | Peptido tipo glucagon; dimero que comprende dos de dichos peptidos; composicion farmaceutica que lo comprende; y su uso para tratar diabetes o inducir perdida de peso. |
CA2747499A1 (en) | 2008-12-19 | 2010-06-24 | Indiana University Research And Technology Corporation | Amide based glucagon superfamily peptide prodrugs |
MX2011013625A (es) | 2009-06-16 | 2012-01-20 | Univ Indiana Res & Tech Corp | Compuestos glucagon activo de receptor de gip. |
SG177609A1 (en) | 2009-07-13 | 2012-02-28 | Zealand Pharma As | Acylated glucagon analogues |
US8703701B2 (en) | 2009-12-18 | 2014-04-22 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
RU2012136450A (ru) | 2010-01-27 | 2014-03-10 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Конъюгаты антагонист глюкагона - агонист gip и композиции для лечения метаболических расстройств и ожирения |
AR080592A1 (es) | 2010-03-26 | 2012-04-18 | Lilly Co Eli | Peptido con actividad para el gip-r y glp-1-r, formulacion famaceutica que lo comprende, su uso para preparar un medicamento util para el tratamiento de diabetes mellitus y para inducir la perdida de peso |
JP6050746B2 (ja) | 2010-05-13 | 2016-12-21 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | Gタンパク質共役受容体活性を示すグルカゴンスーパーファミリーのペプチド |
US9127088B2 (en) | 2010-05-13 | 2015-09-08 | Indiana University Research And Technology Corporation | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity |
RU2580317C2 (ru) | 2010-06-24 | 2016-04-10 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Пептидные пролекарства, принадлежащие к суперсемейству амид-содержащих глюкагонов |
SG191194A1 (en) | 2010-12-22 | 2013-07-31 | Univ Indiana Res & Tech Corp | Glucagon analogs exhibiting gip receptor activity |
BR112013015861A2 (pt) | 2010-12-22 | 2018-06-05 | Marcadia Biotech Inc | métodos para reduzir ganho de peso ou induzir perda de peso, e para tratar hiperglicemia, reduzir níveis de glicose no sangue, ou normalizar níveis de glicose no sangue. |
US20140031278A1 (en) * | 2011-03-28 | 2014-01-30 | Novo Nordisk A/S | Novel Glucagon Analogues |
EP2694095B1 (de) * | 2011-04-05 | 2018-03-07 | Longevity Biotech, Inc. | Zusammensetzungen mit glukagon-analogen sowie verfahren zu ihrer herstellung und verwendung |
UA126465C2 (uk) | 2011-06-10 | 2022-10-12 | Ханмі Сайенс Ко., Лтд. | Пептид, що має активність оксинтомодуліну, та фармацевтична композиція для лікування ожиріння, яка його містить |
KR102002783B1 (ko) * | 2011-06-10 | 2019-07-24 | 베이징 한미 파마슈티컬 컴퍼니 리미티드 | 포도당 의존성 인슐리노트로핀 폴리펩타이드 유사물질, 이의 약학적 조성물 및 응용 |
EP3502129B1 (de) | 2011-06-17 | 2021-04-07 | Hanmi Science Co., Ltd. | Konjugat mit oxyntomodulin und einem immunglobulin-fragment sowie verwendung davon |
CN103748109A (zh) | 2011-06-22 | 2014-04-23 | 印第安纳大学研究及科技有限公司 | 胰高血糖素/glp-1受体共同激动剂 |
JP6179864B2 (ja) | 2011-06-22 | 2017-08-16 | インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション | グルカゴン/glp−1レセプタコ−アゴニスト |
US9944687B2 (en) | 2011-07-04 | 2018-04-17 | Imperial Innovations Limited | Compounds and their effects on feeding behaviour |
AU2012311484B2 (en) | 2011-09-23 | 2017-04-13 | Novo Nordisk A/S | Novel glucagon analogues |
BR112014007124A2 (pt) | 2011-11-17 | 2017-06-13 | Univ Indiana Res & Tech Corp | superfamília de peptídeos gluxagon que exibem atividade no receptor glicocorticóide |
JP6228187B2 (ja) | 2012-05-03 | 2017-11-08 | ジーランド ファーマ アクティーゼルスカブ | Gip−glp−1デュアルアゴニスト化合物及び方法 |
CN104302772B (zh) | 2012-05-18 | 2017-11-10 | 爱德迪安(北京)生物技术有限公司 | 用于糖尿病治疗的蛋白、蛋白缀合物及其应用 |
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MX2014015558A (es) | 2012-06-21 | 2015-03-05 | Univ Indiana Res & Tech Corp | Analogos de glucagon que exhiben actividad del receptor gip. |
AR091866A1 (es) | 2012-07-23 | 2015-03-04 | Zealand Pharma As | Analogos del glucagon |
KR101968344B1 (ko) | 2012-07-25 | 2019-04-12 | 한미약품 주식회사 | 옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물 |
GB2505941A (en) * | 2012-09-17 | 2014-03-19 | Imp Innovations Ltd | Peptide analogues of glucagon for the treatment of obesity and diabetes |
EP2895506A1 (de) | 2012-09-17 | 2015-07-22 | Imperial Innovations Limited | Peptidanaloga von glucagon und glp1 |
TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
WO2014049610A2 (en) | 2012-09-26 | 2014-04-03 | Cadila Healthcare Limited | Peptides as gip, glp-1 and glucagon receptors triple-agonist |
UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
KR102311517B1 (ko) | 2012-11-06 | 2021-10-14 | 한미약품 주식회사 | 옥신토모듈린과 면역글로불린 단편을 포함하는 단백질 결합체의 액상 제제 |
KR101993393B1 (ko) | 2012-11-06 | 2019-10-01 | 한미약품 주식회사 | 옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물 |
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CN105324125A (zh) * | 2013-03-15 | 2016-02-10 | 印第安纳大学研究及科技有限公司 | 具有长效的前体药物 |
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2010
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- 2010-06-16 WO PCT/US2010/038825 patent/WO2010148089A1/en active Application Filing
- 2010-06-16 IN IN377DEN2012 patent/IN2012DN00377A/en unknown
- 2010-06-16 SG SG2011092772A patent/SG176858A1/en unknown
- 2010-06-16 CA CA2765026A patent/CA2765026A1/en not_active Abandoned
- 2010-06-16 EP EP10790117.5A patent/EP2443146B1/de not_active Not-in-force
- 2010-06-16 JP JP2012516264A patent/JP5887265B2/ja not_active Expired - Fee Related
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- 2010-06-16 CN CN201080027026.5A patent/CN102459325B/zh not_active Expired - Fee Related
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CN102459325A (zh) | 2012-05-16 |
JP5887265B2 (ja) | 2016-03-16 |
CL2011003173A1 (es) | 2012-05-25 |
PE20120914A1 (es) | 2012-08-22 |
SG176858A1 (en) | 2012-02-28 |
AU2010260058A1 (en) | 2012-02-02 |
AU2010260058B2 (en) | 2015-09-24 |
RU2012101274A (ru) | 2013-07-27 |
HK1169998A1 (en) | 2013-02-15 |
US20160052989A1 (en) | 2016-02-25 |
IL216881A (en) | 2016-08-31 |
CA2765026A1 (en) | 2010-12-23 |
IL216881A0 (en) | 2012-02-29 |
CN102459325B (zh) | 2015-03-25 |
BRPI1014508A2 (pt) | 2016-04-05 |
KR20120087875A (ko) | 2012-08-07 |
EP2443146B1 (de) | 2016-10-05 |
US9150632B2 (en) | 2015-10-06 |
TW201103556A (en) | 2011-02-01 |
JP2012530145A (ja) | 2012-11-29 |
TWI549687B (zh) | 2016-09-21 |
WO2010148089A1 (en) | 2010-12-23 |
US9790263B2 (en) | 2017-10-17 |
EP2443146A4 (de) | 2012-11-21 |
EP2443146A1 (de) | 2012-04-25 |
MX2011013625A (es) | 2012-01-20 |
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