ATE417622T1
(de)
|
1996-08-08 |
2009-01-15 |
Amylin Pharmaceuticals Inc |
Regulation gastrointestinaler beweglichkeit
|
WO1998030231A1
(en)
|
1997-01-07 |
1998-07-16 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for the reduction of food intake
|
US7157555B1
(en)
*
|
1997-08-08 |
2007-01-02 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
ES2293688T5
(es)
*
|
1997-08-08 |
2011-05-04 |
Amylin Pharmaceuticals, Inc. |
Nuevos compuestos análogos de la exendina.
|
EP1032587B2
(en)
†
|
1997-11-14 |
2013-03-13 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
JP2003522721A
(ja)
*
|
1997-11-14 |
2003-07-29 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
新規なエキセンジンアゴニスト化合物
|
EP1941900A1
(en)
*
|
1997-11-14 |
2008-07-09 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
US7220721B1
(en)
|
1997-11-14 |
2007-05-22 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist peptides
|
EP1938830A1
(en)
*
|
1997-11-14 |
2008-07-02 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
EP1840134B1
(en)
|
1998-02-27 |
2016-04-13 |
Novo Nordisk A/S |
GLP-1 derivatives
|
JP2003522099A
(ja)
|
1998-02-27 |
2003-07-22 |
ノボ ノルディスク アクティーゼルスカブ |
遅延作用プロファイルを有するglp−1のglp−1誘導体及びエキセンジン
|
WO1999064061A1
(en)
|
1998-06-12 |
1999-12-16 |
Bionebraska, Inc. |
GLUCAGON-LIKE PEPTIDE-1 IMPROVES β-CELL RESPONSE TO GLUCOSE IN SUBJECTS WITH IMPAIRED GLUCOSE TOLERANCE
|
EP1100530B1
(en)
|
1998-07-31 |
2003-10-08 |
Novo Nordisk A/S |
In-vitro stimulation of beta cell proliferation
|
ES2278589T3
(es)
*
|
1999-01-14 |
2007-08-16 |
Amylin Pharmaceuticals, Inc. |
Excendinas destinadas a la inhibicion de glucagon.
|
US7399489B2
(en)
|
1999-01-14 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Exendin analog formulations
|
NZ512663A
(en)
*
|
1999-01-14 |
2004-05-28 |
Amylin Pharmaceuticals Inc |
Novel exendin agonist formulations and methods of administration thereof
|
US6605648B1
(en)
*
|
1999-04-06 |
2003-08-12 |
Phillips Plastics Corporation |
Sinterable structures and method
|
AU775063C
(en)
|
1999-04-30 |
2005-05-12 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
US6924264B1
(en)
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
US6514500B1
(en)
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
EP1180121B9
(en)
*
|
1999-05-17 |
2004-09-08 |
Conjuchem, Inc. |
Long lasting insulinotropic peptides
|
US20090175821A1
(en)
*
|
1999-05-17 |
2009-07-09 |
Bridon Dominique P |
Modified therapeutic peptides with extended half-lives in vivo
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
US6844321B2
(en)
|
2000-01-31 |
2005-01-18 |
Novo Nordisk A/S |
Crystallization of a GLP-1 analogue
|
EP1263458B1
(en)
|
2000-03-08 |
2005-11-16 |
Novo Nordisk A/S |
Lowering serum cholesterol
|
CN1501809B
(zh)
*
|
2000-12-13 |
2012-10-10 |
伊莱利利公司 |
应用胰高血糖素样促胰岛肽的长期治疗方案
|
DK1360202T3
(da)
|
2001-02-16 |
2008-09-22 |
Conjuchem Biotechnologies Inc |
Langvarigt glucagon-lignende peptid 2 (GLP-2) til behandling af gastrointestinale sygdomme og lidelser
|
EP1411968B1
(en)
|
2001-07-31 |
2008-09-17 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Glp-1 exendin-4 peptide analogs and uses thereof
|
US7544657B2
(en)
*
|
2002-10-02 |
2009-06-09 |
Zealand Pharma A/S |
Stabilized Exendin-4 compounds
|
AU2003282955A1
(en)
*
|
2002-10-17 |
2004-05-04 |
Alkermes Controlled Therapeutics, Inc. Ii |
Microencapsulation and sustained release of biologically active polypeptides
|
US7731947B2
(en)
|
2003-11-17 |
2010-06-08 |
Intarcia Therapeutics, Inc. |
Composition and dosage form comprising an interferon particle formulation and suspending vehicle
|
WO2005000222A2
(en)
*
|
2003-05-30 |
2005-01-06 |
Amylin Pharmaceuticals, Inc. |
Novel methods and compositions for enhanced transmucosal delivery of peptides and proteins
|
US8263084B2
(en)
|
2003-11-13 |
2012-09-11 |
Hanmi Science Co., Ltd |
Pharmaceutical composition for treating obesity-related disease comprising insulinotropic peptide conjugate
|
KR101135244B1
(ko)
*
|
2007-11-29 |
2012-04-24 |
한미사이언스 주식회사 |
인슐린 분비 펩타이드 결합체를 포함하는 비만 관련질환 치료용 조성물
|
PT3300721T
(pt)
|
2003-11-20 |
2019-06-06 |
Novo Nordisk As |
Formulações peptidicas contendo propileno glicol que sao ideais para a produção e para utilizacao em dispositivos de injeção
|
JP4865565B2
(ja)
|
2003-12-09 |
2012-02-01 |
ノヴォ ノルディスク アー/エス |
Glp−1アゴニストを用いた食物選択の制御
|
US20060074025A1
(en)
*
|
2003-12-26 |
2006-04-06 |
Nastech Pharmaceutical Company Inc. |
Therapeutic formulations for transmucosal administration that increase glucagon-like peptide-1 bioavailability
|
US20060210614A1
(en)
*
|
2003-12-26 |
2006-09-21 |
Nastech Pharmaceutical Company Inc. |
Method of treatment of a metabolic disease using intranasal administration of exendin peptide
|
US20050143303A1
(en)
*
|
2003-12-26 |
2005-06-30 |
Nastech Pharmaceutical Company Inc. |
Intranasal administration of glucose-regulating peptides
|
US20080318837A1
(en)
*
|
2003-12-26 |
2008-12-25 |
Nastech Pharmaceutical Company Inc. |
Pharmaceutical Formation For Increased Epithelial Permeability of Glucose-Regulating Peptide
|
PL1745078T3
(pl)
*
|
2004-04-23 |
2009-12-31 |
Conjuchem Biotechnologies Inc |
Sposób oczyszczania koniugatów albumin
|
JP2008501765A
(ja)
|
2004-06-11 |
2008-01-24 |
ノボ ノルディスク アクティーゼルスカブ |
Glp−1アゴニストを用いた薬剤誘発性肥満の中和
|
DE102004043153B4
(de)
*
|
2004-09-03 |
2013-11-21 |
Philipps-Universität Marburg |
Erfindung betreffend GLP-1 und Exendin
|
AU2012202855B2
(en)
*
|
2004-09-03 |
2015-02-26 |
Philipps-Universitat Marburg |
GLP-1 and exendin related invention
|
US8716221B2
(en)
|
2005-01-14 |
2014-05-06 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
CA2603630C
(en)
*
|
2005-01-14 |
2015-06-09 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
WO2006083761A2
(en)
|
2005-02-03 |
2006-08-10 |
Alza Corporation |
Solvent/polymer solutions as suspension vehicles
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
CN100429227C
(zh)
|
2005-06-29 |
2008-10-29 |
常州制药厂有限公司 |
Exendin4多肽片段
|
EP1959986B1
(en)
|
2005-11-07 |
2014-07-23 |
Indiana University Research and Technology Corporation |
Glucagon analogs exhibiting physiological solubility and stability
|
US8039432B2
(en)
*
|
2005-11-09 |
2011-10-18 |
Conjuchem, Llc |
Method of treatment of diabetes and/or obesity with reduced nausea side effect
|
WO2007061434A2
(en)
*
|
2005-11-10 |
2007-05-31 |
Nastech Pharmaceutical Company Inc. |
A pharmaceutical formulation of glp-1 and its use for treating a metabolic syndrome
|
RU2008124109A
(ru)
*
|
2005-12-08 |
2010-01-20 |
МДРНА, Инк. (US) |
Чресслизистая доставка стабилизированных композиций эксендина
|
JP2009520469A
(ja)
*
|
2005-12-22 |
2009-05-28 |
コンジュクヘム ビオテクフノロギエス インコーポレイテッド |
アルブミンと治療薬との前もって形成された抱合体の産生のための方法
|
ES2351527T3
(es)
|
2006-05-30 |
2011-02-07 |
Intarcia Therapeutics, Inc |
Modulador de flujo en dos piezas con conducto interno para un sistema osmótico de administración.
|
EP2359808B1
(en)
|
2006-08-09 |
2013-05-22 |
Intarcia Therapeutics, Inc |
Osmotic delivery systems and piston assemblies
|
RU2413528C2
(ru)
|
2007-01-18 |
2011-03-10 |
Открытое Акционерное Общество "Валента Фармацевтика" |
Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения
|
MX2009008241A
(es)
|
2007-02-15 |
2009-10-08 |
Univ Indiana Res & Tech Corp |
Co-agonistas de receptor de glucagon/glp-1.
|
KR100746658B1
(ko)
|
2007-04-23 |
2007-08-06 |
성균관대학교산학협력단 |
소수성 담즙산이 접합된 엑센딘-4 유도체, 이의 제조방법및 이를 포함하는 약학 조성물
|
EP2157967B1
(en)
|
2007-04-23 |
2013-01-16 |
Intarcia Therapeutics, Inc |
Suspension formulations of insulinotropic peptides and uses thereof
|
JP2009019027A
(ja)
|
2007-07-16 |
2009-01-29 |
Hanmi Pharmaceutical Co Ltd |
アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体
|
US20100256056A1
(en)
*
|
2007-09-07 |
2010-10-07 |
Zheng Xin Dong |
Analogues of exendin-4 and exendin-3
|
JP5771005B2
(ja)
|
2007-10-30 |
2015-08-26 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
グルカゴンアンタゴニスト及びglp−1アゴニスト活性を示す化合物
|
US20090186819A1
(en)
*
|
2007-12-11 |
2009-07-23 |
Marieve Carrier |
Formulation of insulinotropic peptide conjugates
|
CA2726861C
(en)
|
2008-02-13 |
2014-05-27 |
Intarcia Therapeutics, Inc. |
Devices, formulations, and methods for delivery of multiple beneficial agents
|
US20090221453A1
(en)
*
|
2008-02-29 |
2009-09-03 |
Sumitra Mukhopadhyay |
Treatment Fluid With Oxidizer Breaker System and Method
|
EA019203B9
(ru)
|
2008-06-17 |
2014-03-31 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Коагонисты глюкагонового рецептора/glp-1-рецептора
|
JP6108659B2
(ja)
|
2008-06-17 |
2017-04-05 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
代謝疾患および肥満の治療のためのgipに基づいた混合アゴニスト
|
LT2349324T
(lt)
|
2008-10-17 |
2017-12-27 |
Sanofi-Aventis Deutschland Gmbh |
Insulino ir glp-1 agonisto derinys
|
US9441028B2
(en)
|
2008-12-08 |
2016-09-13 |
Novo Nordisk A/S |
Counter current purification of polypeptides
|
AR074811A1
(es)
|
2008-12-19 |
2011-02-16 |
Univ Indiana Res & Tech Corp |
Profarmaco de peptido de la superfamilia de glucagon basados en amida
|
CN101463078B
(zh)
*
|
2009-01-12 |
2011-07-27 |
华东师范大学 |
一种Exendin-4衍生物及其固相化学合成
|
CN102459325B
(zh)
|
2009-06-16 |
2015-03-25 |
印第安纳大学科技研究有限公司 |
胃抑胜肽受体活化的胰高血糖素化合物
|
EP3323423B1
(en)
|
2009-09-28 |
2020-06-17 |
Intarcia Therapeutics, Inc |
Rapid establishment and/or termination of substantial steady-state drug delivery
|
PL2498801T3
(pl)
|
2009-11-13 |
2018-08-31 |
Sanofi Aventis Deutschland |
Kompozycja farmaceutyczna zawierająca desPro<sup>36</sup>eksendyno-4(1-39)-Lys6-NH2 i metioninę
|
ES2534191T3
(es)
|
2009-11-13 |
2015-04-20 |
Sanofi-Aventis Deutschland Gmbh |
Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina
|
EP2504019A2
(en)
|
2009-11-25 |
2012-10-03 |
ArisGen SA |
Mucosal delivery composition comprising a peptide complexed with a crown compound and/or a counter ion
|
EP2512503A4
(en)
*
|
2009-12-18 |
2013-08-21 |
Univ Indiana Res & Tech Corp |
COAGONISTS OF GLUCAGON / GLP-1 RECEPTOR
|
KR20120123443A
(ko)
|
2010-01-27 |
2012-11-08 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
대사 장애 및 비만 치료용 글루카곤 길항제-gip 항진제 콘쥬게이트
|
US9422330B2
(en)
|
2010-03-01 |
2016-08-23 |
Novo Nordisk A/S |
Preparative RP-HPLC method for purifying peptides
|
US9168288B2
(en)
|
2010-04-09 |
2015-10-27 |
Mount Sinai Hospital |
Methods for treating disorders of the gastrointestinal tract using a GLP-1 agonist
|
CA2797133C
(en)
|
2010-04-27 |
2019-08-06 |
Zealand Pharma A/S |
Peptide conjugates of glp-1 receptor agonists and gastrin and their use
|
HUE031181T2
(en)
|
2010-08-30 |
2017-06-28 |
Sanofi Aventis Deutschland |
Use of AVE0010 for the manufacture of a medicament for the treatment of type 2 diabetes
|
ES2713952T3
(es)
|
2010-12-22 |
2019-05-24 |
Univ Indiana Res & Tech Corp |
Análogos de glucagón que muestran actividad de receptor de GIP
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
CN103918055B
(zh)
*
|
2011-03-31 |
2016-08-17 |
Dh科技发展私人贸易有限公司 |
用于校准质谱仪的组合物、方法和试剂盒
|
US9821032B2
(en)
|
2011-05-13 |
2017-11-21 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
|
RS56173B1
(sr)
|
2011-06-22 |
2017-11-30 |
Univ Indiana Res & Tech Corp |
Koagonisti receptora za glukagon/glp-1 receptora
|
BR112013032717A2
(pt)
|
2011-06-22 |
2017-01-24 |
Univ Indiana Res & Tech Corp |
coagonistas do receptor de glucagon/glp-1
|
CN108079281A
(zh)
|
2011-08-29 |
2018-05-29 |
赛诺菲-安万特德国有限公司 |
用于2型糖尿病患者中的血糖控制的药物组合
|
AR087744A1
(es)
|
2011-09-01 |
2014-04-16 |
Sanofi Aventis Deutschland |
Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
|
EA028951B9
(ru)
|
2011-11-03 |
2018-05-31 |
Зилэнд Фарма А/С |
Пептидные конъюгаты агониста рецептора гастрина и глюкагон подобного пептида 1
|
JP2015500823A
(ja)
|
2011-12-09 |
2015-01-08 |
ノヴォ ノルディスク アー/エス |
Glp−1アゴニスト
|
WO2013170636A1
(zh)
|
2012-05-18 |
2013-11-21 |
爱德迪安(北京)生物技术有限公司 |
用于糖尿病治疗的蛋白、蛋白缀合物及其应用
|
EP2864351B1
(en)
|
2012-06-21 |
2016-08-10 |
Indiana University Research and Technology Corporation |
Glucagon analogs exhibiting gip receptor activity
|
AR091866A1
(es)
|
2012-07-23 |
2015-03-04 |
Zealand Pharma As |
Analogos del glucagon
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
KR20140088837A
(ko)
|
2013-01-03 |
2014-07-11 |
한미약품 주식회사 |
N-말단 전하가 변형된 인슐린 분비 펩티드 유도체
|
TWI780236B
(zh)
|
2013-02-04 |
2022-10-11 |
法商賽諾菲公司 |
胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
|
ES2688708T3
(es)
|
2013-10-17 |
2018-11-06 |
Zealand Pharma A/S |
Análogos de glucagón acilados
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
CN105829339B
(zh)
|
2013-11-06 |
2021-03-12 |
西兰制药公司 |
胰高血糖素-glp-1-gip三重激动剂化合物
|
MX2016005556A
(es)
|
2013-11-06 |
2016-07-15 |
Zealand Pharma As |
Compuestos agonistas duales de gip-glp-1 y procedimientos.
|
WO2015081891A1
(en)
|
2013-12-06 |
2015-06-11 |
Baikang (Suzhou) Co., Ltd |
Bioreversable promoieties for nitrogen-containing and hydroxyl-containing drugs
|
SG11201604708VA
(en)
|
2014-01-09 |
2016-07-28 |
Sanofi Sa |
Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
KR20160104724A
(ko)
|
2014-01-09 |
2016-09-05 |
사노피 |
인슐린 유사체 및/또는 인슐린 유도체의 안정화된 약제학적 제형
|
CN114939156A
(zh)
|
2014-01-09 |
2022-08-26 |
赛诺菲 |
门冬胰岛素的稳定化药物制剂
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
JP6898231B6
(ja)
|
2014-10-29 |
2021-07-28 |
ジーランド ファーマ アクティーゼルスカブ |
Gipアゴニスト化合物及び方法
|
US9950039B2
(en)
|
2014-12-12 |
2018-04-24 |
Sanofi-Aventis Deutschland Gmbh |
Insulin glargine/lixisenatide fixed ratio formulation
|
TWI748945B
(zh)
|
2015-03-13 |
2021-12-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患治療
|
TW201705975A
(zh)
|
2015-03-18 |
2017-02-16 |
賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患之治療
|
AU2016247499B2
(en)
|
2015-04-16 |
2020-09-03 |
Zealand Pharma A/S |
Acylated glucagon analogue
|
MA44390A
(fr)
|
2015-06-03 |
2019-01-23 |
Intarcia Therapeutics Inc |
Systèmes de mise en place et de retrait d'implant
|
CN105753963B
(zh)
*
|
2016-04-13 |
2019-08-30 |
中国药科大学 |
高活性艾塞那肽类似物及其医药应用
|
SG11201810102SA
(en)
|
2016-05-16 |
2018-12-28 |
Intarcia Therapeutics Inc |
Glucagon-receptor selective polypeptides and methods of use thereof
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
KR102502040B1
(ko)
|
2016-12-09 |
2023-02-24 |
질랜드 파마 에이/에스 |
아실화 glp-1/glp-2 이중 효능제
|
CN110225762A
(zh)
|
2017-01-03 |
2019-09-10 |
因塔西亚制药公司 |
包括glp-1受体激动剂的连续施用和药物的共同施用的方法
|
CN109485720A
(zh)
*
|
2017-09-11 |
2019-03-19 |
中国药科大学 |
口服降血糖多肽、其脂肪酸修饰衍生物以及用途
|
TW202024134A
(zh)
|
2018-12-21 |
2020-07-01 |
大陸商江蘇恆瑞醫藥股份有限公司 |
雙特異性蛋白
|
CN116606367A
(zh)
*
|
2022-05-31 |
2023-08-18 |
南京盛德瑞尔医药科技有限公司 |
长效Exendin-9-39及其在低血糖治疗中的应用和作为治疗低血糖的药物
|