PL1745078T3 - Sposób oczyszczania koniugatów albumin - Google Patents

Sposób oczyszczania koniugatów albumin

Info

Publication number
PL1745078T3
PL1745078T3 PL05735795T PL05735795T PL1745078T3 PL 1745078 T3 PL1745078 T3 PL 1745078T3 PL 05735795 T PL05735795 T PL 05735795T PL 05735795 T PL05735795 T PL 05735795T PL 1745078 T3 PL1745078 T3 PL 1745078T3
Authority
PL
Poland
Prior art keywords
albumin
albumin conjugates
conjugates
purification
solution
Prior art date
Application number
PL05735795T
Other languages
English (en)
Inventor
Nathalie Bousquet-Gagnon
Omar Quraishi
Dominique P Bridon
Original Assignee
Conjuchem Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35196920&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1745078(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Conjuchem Biotechnologies Inc filed Critical Conjuchem Biotechnologies Inc
Publication of PL1745078T3 publication Critical patent/PL1745078T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/303—Extraction; Separation; Purification by precipitation by salting out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/166—Fluid composition conditioning, e.g. gradient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent
PL05735795T 2004-04-23 2005-04-22 Sposób oczyszczania koniugatów albumin PL1745078T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56522804P 2004-04-23 2004-04-23
EP05735795A EP1745078B1 (en) 2004-04-23 2005-04-22 Method for the purification of albumin conjugates
PCT/CA2005/000614 WO2005103087A1 (en) 2004-04-23 2005-04-22 Method for the purification of albumin conjugates

Publications (1)

Publication Number Publication Date
PL1745078T3 true PL1745078T3 (pl) 2009-12-31

Family

ID=35196920

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09162758T PL2100904T3 (pl) 2004-04-23 2005-04-22 Stała faza do zastosowania w sposobie oczyszczania koniugatów albuminy
PL05735795T PL1745078T3 (pl) 2004-04-23 2005-04-22 Sposób oczyszczania koniugatów albumin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL09162758T PL2100904T3 (pl) 2004-04-23 2005-04-22 Stała faza do zastosowania w sposobie oczyszczania koniugatów albuminy

Country Status (25)

Country Link
US (3) US7307148B2 (pl)
EP (3) EP1745078B1 (pl)
JP (1) JP2007535507A (pl)
CN (1) CN1956998B (pl)
AT (2) ATE433999T1 (pl)
AU (1) AU2005235634B2 (pl)
BR (1) BRPI0510117A (pl)
CA (1) CA2564031A1 (pl)
DE (2) DE602005022239D1 (pl)
DK (2) DK1745078T3 (pl)
EA (1) EA011168B1 (pl)
ES (2) ES2347902T3 (pl)
HK (2) HK1096102A1 (pl)
HR (1) HRP20060362A2 (pl)
IL (1) IL178369A0 (pl)
MA (1) MA28587B1 (pl)
MX (1) MXPA06012260A (pl)
NO (1) NO20065037L (pl)
PL (2) PL2100904T3 (pl)
PT (2) PT1745078E (pl)
RS (1) RS20060578A (pl)
SI (2) SI2100904T1 (pl)
TN (1) TNSN06340A1 (pl)
WO (1) WO2005103087A1 (pl)
ZA (1) ZA200608475B (pl)

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CN101384623B (zh) * 2005-12-22 2013-07-24 常山凯捷健生物药物研发（河北）有限公司 白蛋白与治疗剂的预成型偶联物的制备方法
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CN105111306A (zh) * 2015-08-28 2015-12-02 北京工业大学 美洲短吻鳄白蛋白的分离方法
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TWI794897B (zh) * 2017-09-28 2023-03-01 南韓商韓美藥品股份有限公司 Ｇｌｐ-２衍生物之長效接合物
CN108840922A (zh) * 2018-06-04 2018-11-20 河北常山生化药业股份有限公司 分离白蛋白非结合物、白蛋白结合物和小分子化合物的方法
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WO2021175275A1 (zh) * 2020-03-06 2021-09-10 昆山新蕴达生物科技有限公司 疏水性修饰的白蛋白及其制备方法和用途
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IL178369A0 (en) 2007-02-11
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CN1956998A (zh) 2007-05-02
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