IN2012DN00377A - - Google Patents

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Publication number
IN2012DN00377A
IN2012DN00377A IN377DEN2012A IN2012DN00377A IN 2012DN00377 A IN2012DN00377 A IN 2012DN00377A IN 377DEN2012 A IN377DEN2012 A IN 377DEN2012A IN 2012DN00377 A IN2012DN00377 A IN 2012DN00377A
Authority
IN
India
Prior art keywords
glucagon
activity
peptides
glp
abstract
Prior art date
Application number
Inventor
D Dimarchi Richard
L Smiley David
Dimarchi Maria
Chabenne Joseph
Day Jonathan
Patterson James
P Ward Brian
Tao Ma
Original Assignee
Univ Indiana Res & Tech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US18757809P priority Critical
Application filed by Univ Indiana Res & Tech Corp filed Critical Univ Indiana Res & Tech Corp
Priority to PCT/US2010/038825 priority patent/WO2010148089A1/en
Publication of IN2012DN00377A publication Critical patent/IN2012DN00377A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons

Abstract

ABSTRACT Glucagon peptides with increased GIP activity are provided  optionally with GLP-I and/or glucagon activity. In some embodiments  C-terminally extended glucagon peptides comprising an amino acid sequence substantially similar to native glucagon are provided herein.
IN377DEN2012 2009-06-16 2010-06-16 IN2012DN00377A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US18757809P true 2009-06-16 2009-06-16
PCT/US2010/038825 WO2010148089A1 (en) 2009-06-16 2010-06-16 Gip receptor-active glucagon compounds

Publications (1)

Publication Number Publication Date
IN2012DN00377A true IN2012DN00377A (en) 2015-08-21

Family

ID=43356738

Family Applications (1)

Application Number Title Priority Date Filing Date
IN377DEN2012 IN2012DN00377A (en) 2009-06-16 2010-06-16

Country Status (18)

Country Link
US (2) US9150632B2 (en)
EP (1) EP2443146B1 (en)
JP (1) JP5887265B2 (en)
KR (1) KR20120087875A (en)
CN (1) CN102459325B (en)
AU (1) AU2010260058B2 (en)
BR (1) BRPI1014508A2 (en)
CA (1) CA2765026A1 (en)
CL (1) CL2011003173A1 (en)
HK (1) HK1169998A1 (en)
IL (1) IL216881A (en)
IN (1) IN2012DN00377A (en)
MX (1) MX2011013625A (en)
PE (1) PE20120914A1 (en)
RU (1) RU2012101274A (en)
SG (1) SG176858A1 (en)
TW (1) TWI549687B (en)
WO (1) WO2010148089A1 (en)

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