IL94983A - Somatostatin and its analogues and preparations with prolonged release of such water-soluble peptides - Google Patents

Somatostatin and its analogues and preparations with prolonged release of such water-soluble peptides

Info

Publication number
IL94983A
IL94983A IL9498390A IL9498390A IL94983A IL 94983 A IL94983 A IL 94983A IL 9498390 A IL9498390 A IL 9498390A IL 9498390 A IL9498390 A IL 9498390A IL 94983 A IL94983 A IL 94983A
Authority
IL
Israel
Prior art keywords
sustained release
release formulation
drug compound
peptide
days
Prior art date
Application number
IL9498390A
Other languages
English (en)
Hebrew (he)
Other versions
IL94983A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to IL11228690A priority Critical patent/IL112286A/en
Priority to IL14168290A priority patent/IL141682A/xx
Publication of IL94983A0 publication Critical patent/IL94983A0/xx
Priority to IL11228695A priority patent/IL112286A0/xx
Publication of IL94983A publication Critical patent/IL94983A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
IL9498390A 1989-07-07 1990-07-05 Somatostatin and its analogues and preparations with prolonged release of such water-soluble peptides IL94983A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL11228690A IL112286A (en) 1989-07-07 1990-07-05 Process for the production of a microparticle and microparticle obtained thereby
IL14168290A IL141682A (en) 1989-07-07 1990-07-05 Process for the production of microparticles using a water-immiscible organic solvent, and a sustained release formulation comprising said microparticles
IL11228695A IL112286A0 (en) 1989-07-07 1995-01-09 Process for the production of a microparticle and microparticle obtained thereby

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37702389A 1989-07-07 1989-07-07
US41134789A 1989-09-22 1989-09-22

Publications (2)

Publication Number Publication Date
IL94983A0 IL94983A0 (en) 1991-06-10
IL94983A true IL94983A (en) 1999-08-17

Family

ID=27007654

Family Applications (3)

Application Number Title Priority Date Filing Date
IL13188090A IL131880A (en) 1989-07-07 1990-07-05 A process for creating microparticles using an oil emulsion in oil, and microparticles created by the process
IL13188190A IL131881A (en) 1989-07-07 1990-07-05 Prolonged-release formulation that includes octride in a polymeric carrier
IL9498390A IL94983A (en) 1989-07-07 1990-07-05 Somatostatin and its analogues and preparations with prolonged release of such water-soluble peptides

Family Applications Before (2)

Application Number Title Priority Date Filing Date
IL13188090A IL131880A (en) 1989-07-07 1990-07-05 A process for creating microparticles using an oil emulsion in oil, and microparticles created by the process
IL13188190A IL131881A (en) 1989-07-07 1990-07-05 Prolonged-release formulation that includes octride in a polymeric carrier

Country Status (27)

Country Link
JP (5) JPH0832624B2 (nl)
KR (2) KR100303681B1 (nl)
AT (1) AT406225B (nl)
AU (2) AU641407B2 (nl)
BE (1) BE1004486A3 (nl)
CA (1) CA2020477C (nl)
CH (1) CH685230A5 (nl)
CY (1) CY1965A (nl)
DE (2) DE4042752B4 (nl)
DK (1) DK175849B1 (nl)
FI (3) FI108611B (nl)
FR (1) FR2649319A1 (nl)
GB (2) GB2234896B (nl)
GR (1) GR1001121B (nl)
HK (2) HK97695A (nl)
HU (2) HU221294B1 (nl)
IE (2) IE64411B1 (nl)
IL (3) IL131880A (nl)
IT (1) IT1241460B (nl)
LU (1) LU87764A1 (nl)
MY (1) MY106722A (nl)
NL (1) NL195027C (nl)
NO (2) NO302928B1 (nl)
NZ (1) NZ234384A (nl)
PT (1) PT94628B (nl)
SE (1) SE512992C2 (nl)
SG (1) SG26416G (nl)

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PT2247282E (pt) 2008-01-30 2014-11-11 Novartis Ag Formulação de libertação controlada compreendendo octreotido e três polímeros lineares de polilactido-coglicolido
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KR102464650B1 (ko) 2016-05-03 2022-11-10 엘에스일렉트릭(주) 배선용 차단기의 한류장치
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Also Published As

Publication number Publication date
JPH08198771A (ja) 1996-08-06
FR2649319B1 (nl) 1994-12-09
IT1241460B (it) 1994-01-17
DE4021517B4 (de) 2009-04-09
AU2332195A (en) 1995-09-07
JPH07285853A (ja) 1995-10-31
NO903001L (no) 1991-01-08
JP2931773B2 (ja) 1999-08-09
NL195027B (nl) 2003-08-01
SG26416G (en) 1995-09-01
PT94628B (pt) 1997-06-30
NZ234384A (en) 1994-05-26
NO903001D0 (no) 1990-07-05
IT9048113A1 (it) 1992-01-05
GR1001121B (el) 1993-04-28
SE9002364D0 (sv) 1990-07-05
IL131881A (en) 2001-12-23
FR2649319A1 (fr) 1991-01-11
FI108611B (fi) 2002-02-28
HU221294B1 (en) 2002-09-28
KR100442931B1 (ko) 2004-08-02
DK162590A (da) 1991-01-08
GB2234896B (en) 1994-01-19
HUT54037A (en) 1991-01-28
GB2265311A (en) 1993-09-29
JPH0368511A (ja) 1991-03-25
NL195027C (nl) 2003-12-02
LU87764A1 (fr) 1992-03-11
HK97695A (en) 1995-06-23
CA2020477C (en) 2000-11-21
HK197496A (en) 1996-11-08
IL131880A (en) 2001-12-23
ATA144090A (de) 1999-08-15
HU903974D0 (en) 1990-11-28
DK162590D0 (da) 1990-07-05
DE4021517A1 (de) 1991-01-17
FI109334B (fi) 2002-07-15
KR100303681B1 (ko) 2002-05-16
IL94983A0 (en) 1991-06-10
JPH0832624B2 (ja) 1996-03-29
HU211602A9 (en) 1995-12-28
DE4042752B4 (de) 2009-05-07
NO302928B1 (no) 1998-05-11
KR910002430A (ko) 1991-02-25
SE9002364L (sv) 1991-01-08
GB9306204D0 (en) 1993-05-19
NO983923D0 (no) 1998-08-26
FI20000060A (fi) 2000-01-12
BE1004486A3 (fr) 1992-12-01
CA2020477A1 (en) 1991-01-08
GR900100513A (en) 1991-12-10
GB2265311B (en) 1994-02-09
FI903429A0 (fi) 1990-07-06
IE64216B1 (en) 1995-07-26
JPH07309897A (ja) 1995-11-28
SE512992C2 (sv) 2000-06-12
FI20000059A (fi) 2000-01-12
NL9001537A (nl) 1991-02-01
PT94628A (pt) 1991-03-20
AU687553B2 (en) 1998-02-26
AU5874690A (en) 1991-01-10
MY106722A (en) 1995-07-31
JP2001233897A (ja) 2001-08-28
GB2234896A (en) 1991-02-20
NO983923L (no) 1991-01-08
GB9014704D0 (en) 1990-08-22
AT406225B (de) 2000-03-27
FI109543B (fi) 2002-08-30
CY1965A (en) 1997-07-04
IE64411B1 (en) 1995-08-09
DK175849B1 (da) 2005-03-29
IE902435A1 (en) 1991-02-13
IT9048113A0 (it) 1990-07-05
CH685230A5 (de) 1995-05-15
NO320444B1 (no) 2005-12-05
AU641407B2 (en) 1993-09-23

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