LU87764A1 - Formulations a liberation prolongee de peptides solubles dans l'eau - Google Patents

Formulations a liberation prolongee de peptides solubles dans l'eau Download PDF

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Publication number
LU87764A1
LU87764A1 LU87764A LU87764A LU87764A1 LU 87764 A1 LU87764 A1 LU 87764A1 LU 87764 A LU87764 A LU 87764A LU 87764 A LU87764 A LU 87764A LU 87764 A1 LU87764 A1 LU 87764A1
Authority
LU
Luxembourg
Prior art keywords
microparticles
water
days
emulsion
oil
Prior art date
Application number
LU87764A
Other languages
English (en)
French (fr)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of LU87764A1 publication Critical patent/LU87764A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU87764A 1989-07-07 1990-07-09 Formulations a liberation prolongee de peptides solubles dans l'eau LU87764A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37702389A 1989-07-07 1989-07-07
US41134789A 1989-09-22 1989-09-22

Publications (1)

Publication Number Publication Date
LU87764A1 true LU87764A1 (fr) 1992-03-11

Family

ID=27007654

Family Applications (1)

Application Number Title Priority Date Filing Date
LU87764A LU87764A1 (fr) 1989-07-07 1990-07-09 Formulations a liberation prolongee de peptides solubles dans l'eau

Country Status (27)

Country Link
JP (5) JPH0832624B2 (nl)
KR (2) KR100303681B1 (nl)
AT (1) AT406225B (nl)
AU (2) AU641407B2 (nl)
BE (1) BE1004486A3 (nl)
CA (1) CA2020477C (nl)
CH (1) CH685230A5 (nl)
CY (1) CY1965A (nl)
DE (2) DE4042752B4 (nl)
DK (1) DK175849B1 (nl)
FI (3) FI108611B (nl)
FR (1) FR2649319A1 (nl)
GB (2) GB2234896B (nl)
GR (1) GR1001121B (nl)
HK (2) HK97695A (nl)
HU (2) HU221294B1 (nl)
IE (2) IE64411B1 (nl)
IL (3) IL131881A (nl)
IT (1) IT1241460B (nl)
LU (1) LU87764A1 (nl)
MY (1) MY106722A (nl)
NL (1) NL195027C (nl)
NO (2) NO302928B1 (nl)
NZ (1) NZ234384A (nl)
PT (1) PT94628B (nl)
SE (1) SE512992C2 (nl)
SG (1) SG26416G (nl)

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CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
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ES2236700T3 (es) 1993-11-19 2005-07-16 Janssen Pharmaceutica N.V. 1,2-benzazoles microencapsulados.
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US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
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US6226656B1 (en) 1998-11-12 2001-05-01 Sourcefinder, Inc. System and method for creating, generating and processing user-defined generic specs
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US6204308B1 (en) 1999-03-01 2001-03-20 Novartis Ag Organic compounds
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US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
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US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
AR044852A1 (es) * 2003-06-24 2005-10-05 Novartis Ag Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina
CA2915574C (en) * 2003-07-18 2017-02-07 Oakwood Laboratories, L.L.C. Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions
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EP1719523A4 (en) * 2004-02-26 2009-07-15 Japan Science & Tech Agency MICROPARTICULAR PROTEIN CARBIDE RETARD PREPARATION FOR INJECTION AND METHOD FOR THE PRODUCTION THEREOF
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KR100741867B1 (ko) * 2005-07-05 2007-07-24 전북대학교산학협력단 수중유적 및 용매 증발법을 이용한 이중층 미립구의제조방법
IN2015DN03936A (nl) * 2005-12-22 2015-10-02 Novartis Ag
KR100816065B1 (ko) * 2006-11-27 2008-03-24 동국제약 주식회사 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐
KR20100110848A (ko) 2008-01-30 2010-10-13 노파르티스 아게 옥트레오티드 및 3종의 선형 폴리락티드-코-글리콜리드 중합체를 포함하는 서방형 제제
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
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JP2013538855A (ja) * 2010-09-30 2013-10-17 エボニック コーポレイション 低い残留有機溶剤の微粒子を製造するためのエマルション法
TW201605488A (zh) 2013-10-15 2016-02-16 大塚製藥股份有限公司 用以預防及／或治療多囊腎病之藥物
KR102464650B1 (ko) 2016-05-03 2022-11-10 엘에스일렉트릭(주) 배선용 차단기의 한류장치
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Also Published As

Publication number Publication date
MY106722A (en) 1995-07-31
NO903001D0 (no) 1990-07-05
DE4021517B4 (de) 2009-04-09
IL131881A (en) 2001-12-23
CA2020477A1 (en) 1991-01-08
HU221294B1 (en) 2002-09-28
IE64216B1 (en) 1995-07-26
JP2931773B2 (ja) 1999-08-09
PT94628B (pt) 1997-06-30
FI108611B (fi) 2002-02-28
NZ234384A (en) 1994-05-26
NO903001L (no) 1991-01-08
DK175849B1 (da) 2005-03-29
IT9048113A0 (it) 1990-07-05
AU2332195A (en) 1995-09-07
AU687553B2 (en) 1998-02-26
BE1004486A3 (fr) 1992-12-01
PT94628A (pt) 1991-03-20
IT1241460B (it) 1994-01-17
GB2234896B (en) 1994-01-19
JPH0368511A (ja) 1991-03-25
NO302928B1 (no) 1998-05-11
IE902435A1 (en) 1991-02-13
DE4042752B4 (de) 2009-05-07
IL94983A (en) 1999-08-17
HU903974D0 (en) 1990-11-28
IL94983A0 (en) 1991-06-10
SG26416G (en) 1995-09-01
JPH07285853A (ja) 1995-10-31
HK97695A (en) 1995-06-23
GB9306204D0 (en) 1993-05-19
GR1001121B (el) 1993-04-28
HUT54037A (en) 1991-01-28
FI903429A0 (fi) 1990-07-06
SE512992C2 (sv) 2000-06-12
NL195027C (nl) 2003-12-02
JPH0832624B2 (ja) 1996-03-29
IE64411B1 (en) 1995-08-09
GB2234896A (en) 1991-02-20
JPH08198771A (ja) 1996-08-06
DK162590A (da) 1991-01-08
FI20000059A (fi) 2000-01-12
IT9048113A1 (it) 1992-01-05
GB2265311B (en) 1994-02-09
ATA144090A (de) 1999-08-15
SE9002364L (sv) 1991-01-08
DK162590D0 (da) 1990-07-05
GB2265311A (en) 1993-09-29
FR2649319A1 (fr) 1991-01-11
AU641407B2 (en) 1993-09-23
HU211602A9 (en) 1995-12-28
FR2649319B1 (nl) 1994-12-09
HK197496A (en) 1996-11-08
NO983923D0 (no) 1998-08-26
KR100442931B1 (ko) 2004-08-02
DE4021517A1 (de) 1991-01-17
NL195027B (nl) 2003-08-01
FI109543B (fi) 2002-08-30
CH685230A5 (de) 1995-05-15
CY1965A (en) 1997-07-04
FI20000060A (fi) 2000-01-12
NO320444B1 (no) 2005-12-05
NO983923L (no) 1991-01-08
GR900100513A (en) 1991-12-10
AT406225B (de) 2000-03-27
NL9001537A (nl) 1991-02-01
FI109334B (fi) 2002-07-15
CA2020477C (en) 2000-11-21
JPH07309897A (ja) 1995-11-28
KR100303681B1 (ko) 2002-05-16
GB9014704D0 (en) 1990-08-22
JP2001233897A (ja) 2001-08-28
IL131880A (en) 2001-12-23
AU5874690A (en) 1991-01-10
KR910002430A (ko) 1991-02-25
SE9002364D0 (sv) 1990-07-05

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