IL90062A - History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them - Google Patents

History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL90062A
IL90062A IL9006289A IL9006289A IL90062A IL 90062 A IL90062 A IL 90062A IL 9006289 A IL9006289 A IL 9006289A IL 9006289 A IL9006289 A IL 9006289A IL 90062 A IL90062 A IL 90062A
Authority
IL
Israel
Prior art keywords
group
amino
cis
compound
oxo
Prior art date
Application number
IL9006289A
Other languages
English (en)
Hebrew (he)
Other versions
IL90062A0 (en
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of IL90062A0 publication Critical patent/IL90062A0/xx
Publication of IL90062A publication Critical patent/IL90062A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
IL9006289A 1988-04-27 1989-04-24 History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them IL90062A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10462588 1988-04-27
JP29698488 1988-11-24

Publications (2)

Publication Number Publication Date
IL90062A0 IL90062A0 (en) 1989-12-15
IL90062A true IL90062A (en) 1994-10-07

Family

ID=26445063

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9006289A IL90062A (en) 1988-04-27 1989-04-24 History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them

Country Status (26)

Country Link
US (4) US5587386A (ko)
EP (1) EP0341493B1 (ko)
JP (5) JP2714597B2 (ko)
KR (1) KR0184614B1 (ko)
CN (1) CN1033751C (ko)
AT (1) ATE182145T1 (ko)
AU (1) AU625414B2 (ko)
BG (1) BG61122B2 (ko)
CA (1) CA1340801C (ko)
DE (1) DE68929030T2 (ko)
DK (1) DK175467B1 (ko)
ES (1) ES2135372T3 (ko)
FI (1) FI96947C (ko)
GR (1) GR3031365T3 (ko)
HK (1) HK1002108A1 (ko)
HU (1) HU211136A9 (ko)
IL (1) IL90062A (ko)
LV (1) LV10092B (ko)
MY (1) MY105136A (ko)
NO (1) NO175939C (ko)
NZ (1) NZ228893A (ko)
PT (1) PT90377B (ko)
RU (1) RU2075475C1 (ko)
SG (1) SG48036A1 (ko)
UA (1) UA29378C2 (ko)
YU (1) YU48432B (ko)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
HU208005B (en) * 1990-02-19 1993-07-28 Kyorin Seiyaku Kk Process for producing optically active 8-methoxy-quinolone-carboxylic acid derivatives and pharmaceutical compositions containing them
MY109714A (en) * 1990-10-18 1997-04-30 Daiichi Seiyaku Co Process for preparing 8-chloroquinolone derivatives
AU661999B2 (en) * 1991-05-28 1995-08-17 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivative
WO1992022550A1 (en) * 1991-06-19 1992-12-23 Pfizer Inc. Azaspiro quinolone antibacterial agents
KR960011370B1 (ko) * 1991-12-31 1996-08-22 재단법인 한국화학연구소 스피로알킬아민 유도체와 그의 제조방법
JP3268098B2 (ja) * 1992-12-25 2002-03-25 第一製薬株式会社 二環性環状アミン誘導体
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
CA2194435A1 (en) * 1994-07-18 1996-02-01 Tomio Kimura Trifluoromethylquinolinecarboxylic acid derivative
US5849757A (en) * 1995-02-02 1998-12-15 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials
EP0816355B1 (en) * 1995-02-07 2003-05-14 Daiichi Pharmaceutical Co., Ltd. Heterocyclic spiro derivatives
JPH09124556A (ja) 1995-08-30 1997-05-13 Dai Ichi Seiyaku Co Ltd ハロゲン化シクロプロパン誘導体の製造方法
KR19990071558A (ko) * 1995-11-22 1999-09-27 스즈키 다다시 치환된 아미노시클로알킬피롤리딘 유도체
US6121285A (en) * 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
CN100395244C (zh) * 1996-02-09 2008-06-18 富山化学工业株式会社 喹诺酮羧酸衍生物或它们的盐类
TW425394B (en) * 1996-04-24 2001-03-11 Daiichi Seiyaku Co Antimicrobial quinolone derivatives having 3-(N-cycloalkyl) aminomethylpyrrolidine group
AU1040597A (en) * 1996-12-04 1998-06-29 Daiichi Pharmaceutical Co., Ltd. Substituted aminomethylpyrrolidine derivatives
EP1134219B1 (en) 1998-11-24 2005-06-15 Daiichi Pharmaceutical Co., Ltd. Cycloalkyl-substituted aminomethylpyrrolidine derivatives
KR20010102560A (ko) * 1999-03-10 2001-11-15 스즈키 다다시 방향족 치환기를 갖는 아미노메틸피롤리딘 유도체
CN1343128B (zh) 1999-03-17 2010-04-21 第一制药株式会社 药物组合物
US7176313B2 (en) 2000-02-09 2007-02-13 Daiichi Pharmaceutical Co., Ltd. Anti acid-fast bacterial agent containing pyridonecarboxylic acids as active ingredient
WO2001072738A1 (fr) * 2000-03-31 2001-10-04 Daiichi Pharmaceutical Co., Ltd. Derive d'acide quinolone-carboxylique
AU2001248833A1 (en) * 2000-04-24 2001-11-07 Daiichi Pharmaceutical Co., Ltd. Stable liquid preparation
US6861071B2 (en) * 2000-08-08 2005-03-01 Daiichi Pharmaceutical Co., Ltd. Highly absorptive solid preparation
AU2003234810A1 (en) * 2002-05-17 2003-12-02 Daiichi Pharmaceutical Co., Ltd. Process for producing quinolonecarboxylic acid derivative
EP1582513B1 (en) * 2003-01-07 2010-11-17 Daiichi Sankyo Company, Limited Process for reductive dehalogenation
US7085154B2 (en) * 2003-06-03 2006-08-01 Samsung Electronics Co., Ltd. Device and method for pulse width control in a phase change memory device
JP4820290B2 (ja) 2004-05-13 2011-11-24 第一三共株式会社 置換ピロリジン誘導体
JP5063032B2 (ja) * 2005-05-19 2012-10-31 第一三共株式会社 トリ−、テトラ−置換−３−アミノピロリジン誘導体
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
US7928232B2 (en) 2005-05-20 2011-04-19 Daiichi Sankyo Company, Limited Method for producing asymmetric tetrasubstituted carbon atom-containing compound
US7977346B2 (en) 2006-01-17 2011-07-12 Guoqing Paul Chen Spiro compounds and methods of use
TWI386401B (zh) * 2006-03-27 2013-02-21 Daiichi Seiyaku Co 醫藥用水合物
SI2097400T1 (sl) 2007-01-05 2013-10-30 Daiichi Sankyo Company, Limited Zliti substituirani aminopirolidinski derivat
EP2311974B1 (en) 2008-07-11 2012-12-19 Sumitomo Chemical Company, Limited Process for producing (1s,2r)-2-chloro-2-fluorocyclopropanecarboxylic acid
FR2961207B1 (fr) * 2010-06-09 2013-01-18 Oreal Utilisation d'un derive de 4- carboxy 2-pyrrolidinone comme solvant dans les compositions cosmetiques ; compositions cosmetiques les contenant ; nouveaux composes
CN103467448B (zh) * 2013-09-18 2015-04-15 浙江司太立制药股份有限公司 7-(3-氨基-4-烷氧亚胺基-1-哌啶基)-1-[(1r,2s)-2-氟环丙基]喹诺酮羧酸类化合物及其制备方法
EP2957561A1 (en) * 2014-06-18 2015-12-23 Université Paris 6 Pierre et Marie Curie UPMC Novel fluoroquinolones and use thereof to treat bacterial infections
CN105330590B (zh) * 2015-10-15 2018-09-25 广州市朗启医药科技有限责任公司 西他沙星五元环侧链中间体的制备方法
CN109912504B (zh) * 2019-04-04 2020-11-10 山东省联合农药工业有限公司 一种喹啉羧酸类化合物及其制备方法与用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6212760A (ja) * 1984-12-14 1987-01-21 Dai Ichi Seiyaku Co Ltd １−（２−ハロゲノシクロプロピル）キノリンカルボン酸誘導体
AU5427286A (en) * 1985-03-08 1986-09-11 Kyorin Pharmaceutical Co. Ltd. 7-(1-pyrrolidinyl)-3-quinolinecarboxylic acid derivatives
DE3509546A1 (de) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4657913A (en) 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
US4735949A (en) 1986-02-18 1988-04-05 Warner-Lambert Company Disubstituted-7-pyrrolidinonaphthyridine antibacterial agents
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
DE3702393A1 (de) * 1987-01-28 1988-08-11 Bayer Ag 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel
US5290934A (en) * 1987-04-16 1994-03-01 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
AU618823B2 (en) * 1988-07-20 1992-01-09 Sankyo Company Limited 4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their use
US5286723A (en) 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
AU5123690A (en) * 1989-03-13 1990-09-13 Bristol-Myers Squibb Company 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
WO2001072738A1 (fr) 2000-03-31 2001-10-04 Daiichi Pharmaceutical Co., Ltd. Derive d'acide quinolone-carboxylique
JP4820290B2 (ja) * 2004-05-13 2011-11-24 第一三共株式会社 置換ピロリジン誘導体

Also Published As

Publication number Publication date
NZ228893A (en) 1990-06-26
UA29378C2 (uk) 2000-11-15
US5587386A (en) 1996-12-24
PT90377A (pt) 1989-11-10
KR0184614B1 (ko) 1999-05-01
AU3370289A (en) 1989-11-02
ATE182145T1 (de) 1999-07-15
DK205789A (da) 1989-10-28
YU87589A (en) 1990-12-31
EP0341493B1 (en) 1999-07-14
PT90377B (pt) 1994-09-30
HK1002108A1 (en) 1998-07-31
HU211136A9 (en) 1995-10-30
NO175939C (no) 1995-01-04
US5767127A (en) 1998-06-16
SG48036A1 (en) 1998-04-17
FI891980A0 (fi) 1989-04-26
EP0341493A3 (en) 1990-12-19
DE68929030T2 (de) 2000-03-23
KR900016205A (ko) 1990-11-12
YU48432B (sh) 1998-07-10
JPH07300416A (ja) 1995-11-14
NO175939B (no) 1994-09-26
AU625414B2 (en) 1992-07-09
DE68929030D1 (de) 1999-08-19
MY105136A (en) 1994-08-30
US6031102A (en) 2000-02-29
CN1037507A (zh) 1989-11-29
ES2135372T3 (es) 1999-11-01
CN1033751C (zh) 1997-01-08
NO891698D0 (no) 1989-04-25
FI96947C (fi) 1996-09-25
JPH11124367A (ja) 1999-05-11
JPH11124380A (ja) 1999-05-11
FI96947B (fi) 1996-06-14
USRE41149E1 (en) 2010-02-23
JP2917010B2 (ja) 1999-07-12
JPH02231475A (ja) 1990-09-13
FI891980A (fi) 1989-10-28
CA1340801C (en) 1999-10-26
JP2714597B2 (ja) 1998-02-16
DK205789D0 (da) 1989-04-27
IL90062A0 (en) 1989-12-15
EP0341493A2 (en) 1989-11-15
JP2903292B2 (ja) 1999-06-07
NO891698L (no) 1989-10-30
GR3031365T3 (en) 2000-01-31
RU2075475C1 (ru) 1997-03-20
BG61122B2 (bg) 1996-11-29
DK175467B1 (da) 2004-11-01
JPH1067779A (ja) 1998-03-10
LV10092B (en) 1995-02-20

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