IL235846A0 - Nitrogen-substituted benzamides and their use for pain treatment - Google Patents

Nitrogen-substituted benzamides and their use for pain treatment

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Publication number
IL235846A0
IL235846A0 IL235846A IL23584614A IL235846A0 IL 235846 A0 IL235846 A0 IL 235846A0 IL 235846 A IL235846 A IL 235846A IL 23584614 A IL23584614 A IL 23584614A IL 235846 A0 IL235846 A0 IL 235846A0
Authority
IL
Israel
Prior art keywords
pain
treatment
substituted benzamides
benzamides
substituted
Prior art date
Application number
IL235846A
Other languages
English (en)
Hebrew (he)
Original Assignee
Genentech Inc
Xenon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Xenon Pharmaceuticals Inc filed Critical Genentech Inc
Publication of IL235846A0 publication Critical patent/IL235846A0/en

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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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