IL155236A0 - Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity - Google Patents

Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity

Info

Publication number
IL155236A0
IL155236A0 IL15523601A IL15523601A IL155236A0 IL 155236 A0 IL155236 A0 IL 155236A0 IL 15523601 A IL15523601 A IL 15523601A IL 15523601 A IL15523601 A IL 15523601A IL 155236 A0 IL155236 A0 IL 155236A0
Authority
IL
Israel
Prior art keywords
sibutramin
association
pharmaceutical compositions
compositions containing
receptor antagonist
Prior art date
Application number
IL15523601A
Other languages
English (en)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8854974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL155236(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of IL155236A0 publication Critical patent/IL155236A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL15523601A 2000-10-04 2001-10-01 Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity IL155236A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0012646A FR2814678B1 (fr) 2000-10-04 2000-10-04 Association d'un antagoniste du recepteur cb1 et de sibutramine, les compositions pharmaceutiques les contenant et leur utilisation pour la traitement de l'obesite
PCT/FR2001/003022 WO2002028346A2 (fr) 2000-10-04 2001-10-01 Association d'un antagoniste du recepteur cb1 et de sibutramine, pour le traitement de l'obesite

Publications (1)

Publication Number Publication Date
IL155236A0 true IL155236A0 (en) 2003-11-23

Family

ID=8854974

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15523601A IL155236A0 (en) 2000-10-04 2001-10-01 Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity

Country Status (29)

Country Link
EP (1) EP1328269B2 (de)
JP (1) JP4221221B2 (de)
KR (1) KR20030036885A (de)
CN (1) CN100409845C (de)
AT (1) ATE267595T1 (de)
AU (2) AU2001293936B2 (de)
BG (1) BG107739A (de)
BR (1) BR0114410A (de)
CA (1) CA2424934A1 (de)
DE (1) DE60103556T3 (de)
DK (1) DK1328269T5 (de)
EA (1) EA005924B1 (de)
EE (1) EE200300121A (de)
ES (1) ES2217191T5 (de)
FR (1) FR2814678B1 (de)
HR (1) HRP20030249A2 (de)
HU (1) HUP0302044A3 (de)
IL (1) IL155236A0 (de)
MX (1) MXPA03002845A (de)
NO (1) NO20031521L (de)
NZ (1) NZ524904A (de)
PL (1) PL362833A1 (de)
PT (1) PT1328269E (de)
SI (1) SI1328269T2 (de)
SK (1) SK4032003A3 (de)
TR (1) TR200401264T4 (de)
WO (1) WO2002028346A2 (de)
YU (1) YU26103A (de)
ZA (1) ZA200303015B (de)

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FR2833842B1 (fr) * 2001-12-21 2004-02-13 Aventis Pharma Sa Compositions pharmaceutiques a base de derives d'azetidine
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AU2003215024B2 (en) 2002-03-26 2008-02-21 Merck Sharp & Dohme Corp. Spirocyclic amides as cannabinoid receptor modulators
US7271266B2 (en) 2002-03-28 2007-09-18 Merck & Co., Inc. Substituted 2,3-diphenyl pyridines
JP4459629B2 (ja) 2002-04-12 2010-04-28 メルク エンド カムパニー インコーポレーテッド 二環式アミド
EP1532132B1 (de) 2002-07-29 2008-03-19 F.Hoffmann-La Roche Ag Neue benzodioxole
MXPA05007114A (es) 2003-01-02 2005-08-26 Hoffmann La Roche Nuevos agonistas inversos del receptor cb1.
JP4271660B2 (ja) 2003-01-02 2009-06-03 エフ．ホフマン−ラ ロシュ アーゲー ピロリル−チアゾール及びｃｂ１受容体逆作動物質としてのその使用
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
CN1802351A (zh) 2003-06-11 2006-07-12 麦克公司 被取代的3－烷基和3－链烯基氮杂环丁烷衍生物
EP1638556B1 (de) 2003-06-20 2008-04-02 F. Hoffmann-La Roche Ag 2-aminobenzothiazole als cb1 rezeptor inverse agonisten
EP1498123A1 (de) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Emulgierende Systeme enthaltend Azetidin Derivate
EP1498122A1 (de) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Halbfeste Systeme enthaltend Azetidin-Derivate
WO2005020992A1 (en) * 2003-09-02 2005-03-10 Solvay Pharmaceuticals Gmbh Novel medical use of selective cb1-receptor antagonists
FR2861303A1 (fr) * 2003-10-24 2005-04-29 Sanofi Synthelabo Utilisation d'un derive de pyrazole pour la preparation de medicaments utiles dans la prevention et le traitement du syndrome metabolique
WO2005049615A1 (en) * 2003-11-21 2005-06-02 Pfizer Products Inc. Pyrazolo`1,5-a!`1,3,5! triazin -4-one derivatives as cb1 receptor antagonists
JP4527729B2 (ja) 2003-12-08 2010-08-18 エフ．ホフマン−ラ ロシュ アーゲー 新規チアゾール誘導体
KR100843023B1 (ko) 2004-01-28 2008-07-01 에프. 호프만-라 로슈 아게 스피로-5환 화합물
CA2564986A1 (en) 2004-05-10 2005-11-17 F. Hoffmann-La Roche Ag Pyrrole or imidazole amides for treating obesity
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
JP2008514718A (ja) * 2004-09-29 2008-05-08 シェーリング コーポレイション 置換アゼチドノンおよびｃｂ１アンタゴニストの組み合わせ
FR2876689B1 (fr) 2004-10-14 2008-02-22 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de derives de n-(1-benzhydryl-azetidin-3-yl)-n-phenyl-methylsulfonamide
MX2007004889A (es) 2004-10-25 2007-09-11 Solvay Pharm Gmbh Composiciones farmaceuticas que comprenden antagonistas del receptor cannabinoide cb1 y activadores de canales de potasio para el tratamiento de la diabetes mellitus tipo i, la obesidad y trastornos relacionados.
KR100912146B1 (ko) 2004-10-27 2009-08-14 에프. 호프만-라 로슈 아게 인돌 또는 벤즈이미다졸 유도체
EP1812418B1 (de) 2004-11-09 2010-10-27 F. Hoffmann-La Roche AG Dibenzosuberon-derivate
WO2006106054A1 (en) 2005-04-06 2006-10-12 F. Hoffmann-La Roche Ag Pyridine-3-carboxamide derivatives as cb1 inverse agonists
US7906652B2 (en) 2005-11-28 2011-03-15 Merck Sharp & Dohme Corp. Heterocycle-substituted 3-alkyl azetidine derivatives
EP1986638A2 (de) * 2006-02-21 2008-11-05 Ampla Pharmaceuticals Inc. Cb1-antagonisten und inverse agonisten
WO2007110449A1 (en) * 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
TW200812963A (en) 2006-04-13 2008-03-16 Euro Celtique Sa Benzenesulfonamide compounds and the use thereof
TW200815353A (en) 2006-04-13 2008-04-01 Euro Celtique Sa Benzenesulfonamide compounds and their use
US7629346B2 (en) 2006-06-19 2009-12-08 Hoffmann-La Roche Inc. Pyrazinecarboxamide derivatives as CB1 antagonists
WO2008038143A2 (en) * 2006-06-22 2008-04-03 Medichem, S.A. Novel solid forms of rimonabant and synthetic processes for their preparation
US20100076022A1 (en) * 2006-09-01 2010-03-25 Hetero Drugs Limited Novel polymorphs of rimonabant
US7781593B2 (en) 2006-09-14 2010-08-24 Hoffmann-La Roche Inc. 5-phenyl-nicotinamide derivatives
CN101516839A (zh) * 2006-09-25 2009-08-26 贝林格尔.英格海姆国际有限公司 调节cb2受体的化合物
DE102007002260A1 (de) 2007-01-16 2008-07-31 Sanofi-Aventis Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
EP1953144A1 (de) * 2007-01-30 2008-08-06 Sandoz AG Polymorphe Formen von N-Piperidin-5-(4-chlorphenyl)-1-(2, 4-dichlorphenyl)-4-methyl-3-pyrazolcarboxamid
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
SI2234966T1 (sl) * 2007-12-18 2014-01-31 Sanofi Derivati azetidinov, njihova priprava in njihova terapevtska uporaba
WO2010079241A1 (es) 2009-01-12 2010-07-15 Fundacion Hospital Nacional De Paraplejicos Para La Investigacion Y La Integracion Uso de antagonistas y/o agonistas inversos de los receptores cb1 para la preparación de medicamentos que incrementen la excitabilidad de las motoneuronas
BRPI0902481B8 (pt) 2009-07-31 2021-05-25 Soc Beneficente De Senhoras Hospital Sirio Libanes composição farmacêutica compreendendo hemopressina e seu uso.
US8410107B2 (en) 2010-10-15 2013-04-02 Hoffmann-La Roche Inc. N-pyridin-3-yl or N-pyrazin-2-yl carboxamides
US8669254B2 (en) 2010-12-15 2014-03-11 Hoffman-La Roche Inc. Pyridine, pyridazine, pyrimidine or pyrazine carboxamides as HDL-cholesterol raising agents

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Also Published As

Publication number Publication date
TR200401264T4 (tr) 2004-07-21
SK4032003A3 (en) 2003-09-11
WO2002028346A3 (fr) 2002-08-29
EP1328269B2 (de) 2008-07-30
JP2004512279A (ja) 2004-04-22
EP1328269B1 (de) 2004-05-26
CN1473040A (zh) 2004-02-04
FR2814678B1 (fr) 2002-12-20
EA005924B1 (ru) 2005-08-25
DK1328269T4 (da) 2008-11-24
HUP0302044A2 (hu) 2003-11-28
KR20030036885A (ko) 2003-05-09
NO20031521D0 (no) 2003-04-03
SI1328269T1 (en) 2004-10-31
DK1328269T3 (da) 2004-09-20
WO2002028346A2 (fr) 2002-04-11
ZA200303015B (en) 2004-02-26
DE60103556T2 (de) 2005-06-30
AU2001293936B2 (en) 2007-01-25
YU26103A (sh) 2006-08-17
DK1328269T5 (da) 2009-03-16
SI1328269T2 (sl) 2008-12-31
EA200300441A1 (ru) 2003-08-28
BG107739A (bg) 2004-01-30
HRP20030249A2 (en) 2005-02-28
AU9393601A (en) 2002-04-15
HUP0302044A3 (en) 2005-05-30
BR0114410A (pt) 2004-02-17
ATE267595T1 (de) 2004-06-15
PL362833A1 (en) 2004-11-02
NZ524904A (en) 2004-11-26
NO20031521L (no) 2003-04-24
MXPA03002845A (es) 2004-09-10
JP4221221B2 (ja) 2009-02-12
EE200300121A (et) 2005-04-15
PT1328269E (pt) 2004-08-31
ES2217191T3 (es) 2004-11-01
FR2814678A1 (fr) 2002-04-05
DE60103556T3 (de) 2009-04-09
CA2424934A1 (fr) 2002-04-11
DE60103556D1 (de) 2004-07-01
CN100409845C (zh) 2008-08-13
ES2217191T5 (es) 2009-02-16
EP1328269A2 (de) 2003-07-23

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