HUP0302044A2 - Egy CB1 receptor antagonista és sibutramin kombinációja, ezt tartalmazó gyógyászati készítmények és alkalmazásuk elhízás kezelésére - Google Patents

Egy CB1 receptor antagonista és sibutramin kombinációja, ezt tartalmazó gyógyászati készítmények és alkalmazásuk elhízás kezelésére

Info

Publication number
HUP0302044A2
HUP0302044A2 HU0302044A HUP0302044A HUP0302044A2 HU P0302044 A2 HUP0302044 A2 HU P0302044A2 HU 0302044 A HU0302044 A HU 0302044A HU P0302044 A HUP0302044 A HU P0302044A HU P0302044 A2 HUP0302044 A2 HU P0302044A2
Authority
HU
Hungary
Prior art keywords
receptor antagonist
sibutramin
association
pharmaceutical compositions
compositions containing
Prior art date
Application number
HU0302044A
Other languages
English (en)
Inventor
Francois Petitet
Philippe Picaut
Odile Piot-Grosjean
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8854974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0302044(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HUP0302044A2 publication Critical patent/HUP0302044A2/hu
Publication of HUP0302044A3 publication Critical patent/HUP0302044A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A találmány egy (I) általános képletű CB1 receptor antagonista éssibutramin, annak hidrátja vagy gyógyászatilag elfogadható sójakombinációjára, az ezeket tartalmazó gyógyászati készítményekre éselhízás kezelésére történő alkalmazásukra vonatkozik. Az (I) általánosképletben R jelentése (A) vagy (B) általános képletű csoport - ahol R1jelentése metil- vagy etilcsoport R2 jelentése fenil-, naftil- vagyindenilcsoport közül választott aromás csoport, amelyek adott esetbenszubsztituáltak lehetnek R3 és R4 jelentése azonos vagy különböző ésjelentése fenil- naftil-, vagy indenilcsoport közül választott aromáscsoportok lehetnek, amelyek adott esetben szubsztituáltak. Ó
HU0302044A 2000-10-04 2001-10-01 Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity HUP0302044A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0012646A FR2814678B1 (fr) 2000-10-04 2000-10-04 Association d'un antagoniste du recepteur cb1 et de sibutramine, les compositions pharmaceutiques les contenant et leur utilisation pour la traitement de l'obesite
PCT/FR2001/003022 WO2002028346A2 (fr) 2000-10-04 2001-10-01 Association d'un antagoniste du recepteur cb1 et de sibutramine, pour le traitement de l'obesite

Publications (2)

Publication Number Publication Date
HUP0302044A2 true HUP0302044A2 (hu) 2003-11-28
HUP0302044A3 HUP0302044A3 (en) 2005-05-30

Family

ID=8854974

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302044A HUP0302044A3 (en) 2000-10-04 2001-10-01 Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity

Country Status (29)

Country Link
EP (1) EP1328269B2 (hu)
JP (1) JP4221221B2 (hu)
KR (1) KR20030036885A (hu)
CN (1) CN100409845C (hu)
AT (1) ATE267595T1 (hu)
AU (2) AU2001293936B2 (hu)
BG (1) BG107739A (hu)
BR (1) BR0114410A (hu)
CA (1) CA2424934A1 (hu)
DE (1) DE60103556T3 (hu)
DK (1) DK1328269T5 (hu)
EA (1) EA005924B1 (hu)
EE (1) EE200300121A (hu)
ES (1) ES2217191T5 (hu)
FR (1) FR2814678B1 (hu)
HR (1) HRP20030249A2 (hu)
HU (1) HUP0302044A3 (hu)
IL (1) IL155236A0 (hu)
MX (1) MXPA03002845A (hu)
NO (1) NO20031521L (hu)
NZ (1) NZ524904A (hu)
PL (1) PL362833A1 (hu)
PT (1) PT1328269E (hu)
SI (1) SI1328269T2 (hu)
SK (1) SK4032003A3 (hu)
TR (1) TR200401264T4 (hu)
WO (1) WO2002028346A2 (hu)
YU (1) YU26103A (hu)
ZA (1) ZA200303015B (hu)

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FR2876689B1 (fr) * 2004-10-14 2008-02-22 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de derives de n-(1-benzhydryl-azetidin-3-yl)-n-phenyl-methylsulfonamide
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BRPI0517369A (pt) 2004-10-27 2008-10-07 Hoffmann La Roche compostos, processo para a sua manufatura, composições que os compreendem, método para o tratamento e/ou profilaxia de enfermidades que estão associadas com a modulação de receptores de cb1 e sua utilização
RU2391337C2 (ru) 2004-11-09 2010-06-10 Ф.Хоффманн-Ля Рош Аг Производные дибензосуберона
CA2602787C (en) 2005-04-06 2013-12-24 F. Hoffmann-La Roche Ag Pyridine-3-carboxamide derivatives as cb1 inverse agonists
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JP5030114B2 (ja) * 2006-09-25 2012-09-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂ２受容体をモジュレートする化合物
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Also Published As

Publication number Publication date
EE200300121A (et) 2005-04-15
KR20030036885A (ko) 2003-05-09
TR200401264T4 (tr) 2004-07-21
HRP20030249A2 (en) 2005-02-28
SI1328269T2 (sl) 2008-12-31
IL155236A0 (en) 2003-11-23
FR2814678A1 (fr) 2002-04-05
EP1328269B2 (fr) 2008-07-30
ES2217191T5 (es) 2009-02-16
HUP0302044A3 (en) 2005-05-30
PL362833A1 (en) 2004-11-02
DE60103556T3 (de) 2009-04-09
NO20031521L (no) 2003-04-24
ES2217191T3 (es) 2004-11-01
SK4032003A3 (en) 2003-09-11
DE60103556D1 (de) 2004-07-01
DK1328269T4 (da) 2008-11-24
AU2001293936B2 (en) 2007-01-25
EP1328269A2 (fr) 2003-07-23
FR2814678B1 (fr) 2002-12-20
CA2424934A1 (fr) 2002-04-11
EA005924B1 (ru) 2005-08-25
JP2004512279A (ja) 2004-04-22
EP1328269B1 (fr) 2004-05-26
DE60103556T2 (de) 2005-06-30
NZ524904A (en) 2004-11-26
WO2002028346A2 (fr) 2002-04-11
PT1328269E (pt) 2004-08-31
EA200300441A1 (ru) 2003-08-28
BG107739A (bg) 2004-01-30
YU26103A (sh) 2006-08-17
CN1473040A (zh) 2004-02-04
BR0114410A (pt) 2004-02-17
ATE267595T1 (de) 2004-06-15
WO2002028346A3 (fr) 2002-08-29
JP4221221B2 (ja) 2009-02-12
CN100409845C (zh) 2008-08-13
NO20031521D0 (no) 2003-04-03
SI1328269T1 (en) 2004-10-31
MXPA03002845A (es) 2004-09-10
DK1328269T3 (da) 2004-09-20
AU9393601A (en) 2002-04-15
DK1328269T5 (da) 2009-03-16
ZA200303015B (en) 2004-02-26

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