IL155236A0 - Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity - Google Patents

Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity

Info

Publication number
IL155236A0
IL155236A0 IL15523601A IL15523601A IL155236A0 IL 155236 A0 IL155236 A0 IL 155236A0 IL 15523601 A IL15523601 A IL 15523601A IL 15523601 A IL15523601 A IL 15523601A IL 155236 A0 IL155236 A0 IL 155236A0
Authority
IL
Israel
Prior art keywords
sibutramin
association
pharmaceutical compositions
compositions containing
receptor antagonist
Prior art date
Application number
IL15523601A
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8854974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL155236(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of IL155236A0 publication Critical patent/IL155236A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The invention concerns the association of the CB1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity.
IL15523601A 2000-10-04 2001-10-01 Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity IL155236A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0012646A FR2814678B1 (en) 2000-10-04 2000-10-04 COMBINATION OF AN ANTAGONIST OF THE CB1 RECEPTOR AND SIBUTRAMINE, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE TREATMENT OF OBESITY
PCT/FR2001/003022 WO2002028346A2 (en) 2000-10-04 2001-10-01 Association of the cb1 receptor antagonist and sibutramin, for treating obesity

Publications (1)

Publication Number Publication Date
IL155236A0 true IL155236A0 (en) 2003-11-23

Family

ID=8854974

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15523601A IL155236A0 (en) 2000-10-04 2001-10-01 Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity

Country Status (29)

Country Link
EP (1) EP1328269B2 (en)
JP (1) JP4221221B2 (en)
KR (1) KR20030036885A (en)
CN (1) CN100409845C (en)
AT (1) ATE267595T1 (en)
AU (2) AU9393601A (en)
BG (1) BG107739A (en)
BR (1) BR0114410A (en)
CA (1) CA2424934A1 (en)
DE (1) DE60103556T3 (en)
DK (1) DK1328269T5 (en)
EA (1) EA005924B1 (en)
EE (1) EE200300121A (en)
ES (1) ES2217191T5 (en)
FR (1) FR2814678B1 (en)
HR (1) HRP20030249A2 (en)
HU (1) HUP0302044A3 (en)
IL (1) IL155236A0 (en)
MX (1) MXPA03002845A (en)
NO (1) NO20031521L (en)
NZ (1) NZ524904A (en)
PL (1) PL362833A1 (en)
PT (1) PT1328269E (en)
SI (1) SI1328269T2 (en)
SK (1) SK4032003A3 (en)
TR (1) TR200401264T4 (en)
WO (1) WO2002028346A2 (en)
YU (1) YU26103A (en)
ZA (1) ZA200303015B (en)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2833842B1 (en) * 2001-12-21 2004-02-13 Aventis Pharma Sa PHARMACEUTICAL COMPOSITIONS BASED ON AZETIDINE DERIVATIVES
CA2478183C (en) 2002-03-12 2010-02-16 Merck & Co. Inc. Substituted amides
US7423067B2 (en) 2002-03-26 2008-09-09 Merck & Co., Inc. Diphenyl cyclopentyl amides as cannabinoid-1 receptor inverse agonists
WO2003082191A2 (en) 2002-03-28 2003-10-09 Merck & Co., Inc. Substituted 2,3-diphenyl pyridines
US7667053B2 (en) 2002-04-12 2010-02-23 Merck & Co., Inc. Bicyclic amides
NZ537685A (en) 2002-07-29 2007-06-29 Hoffmann La Roche Novel benzodioxoles
US7135488B2 (en) 2003-01-02 2006-11-14 Hoffmann-La Roche Inc. Pyrrolyl-thiazole derivatives
PL378206A1 (en) 2003-01-02 2006-03-20 F. Hoffmann-La Roche Ag Novel cb 1 receptour inverse agonists
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
RU2006100298A (en) 2003-06-11 2006-05-10 Мерк энд Ко., Инк. (US) SUBSTITUTED 3-ALKYL-AND 3-ALKENYLASETIDINE DERIVATIVES
CA2528785A1 (en) 2003-06-20 2005-01-06 Matthias Heinrich Nettekoven 2-amidobenzothiazoles as cb1 receptor inverse agonists
EP1498122A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Semi-solid systems containing azetidine derivatives
EP1498123A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Emulsifying systems containing azetidine derivatives
EP1663215A1 (en) * 2003-09-02 2006-06-07 Solvay Pharmaceuticals GmbH Novel medical use of selective cb1- receptor antagonists
FR2861303A1 (en) * 2003-10-24 2005-04-29 Sanofi Synthelabo Use of pyrazole derivative as cannabinoid CB1 receptor antagonist, for treatment and prevention of metabolic syndrome, particularly cardiovascular risks, dyslipidemia and liver disease associated with obesity
WO2005049615A1 (en) * 2003-11-21 2005-06-02 Pfizer Products Inc. Pyrazolo`1,5-a!`1,3,5! triazin -4-one derivatives as cb1 receptor antagonists
WO2005058887A1 (en) 2003-12-08 2005-06-30 F. Hoffmann-La Roche Ag Novel thiazole derivates
BRPI0507120A (en) 2004-01-28 2007-06-19 Hoffmann La Roche compounds, process for the manufacture thereof, pharmaceutical compositions comprising them, method for treating and / or prophylaxis of diseases that are associated with cb1 receptor modulation and their use
EP1749002B1 (en) 2004-05-10 2009-05-27 F.Hoffmann-La Roche Ag Pyrrole or imidazole amides for treating obesity
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
WO2006039334A1 (en) * 2004-09-29 2006-04-13 Schering Corporation Combinations of substituted azetidonones and cb1 antagonists
FR2876689B1 (en) * 2004-10-14 2008-02-22 Aventis Pharma Sa NOVEL PROCESS AND INTERMEDIATES FOR PREPARING N- (1-BENZHYDRYL-AZETIDIN-3-YL) -N-PHENYL-METHYLSULFONAMIDE DERIVATIVES
RU2007119315A (en) 2004-10-25 2008-11-27 Зольвай Фармасьютиклз Гмбх (De) PHARMACEUTICAL COMPOSITIONS CONTAINING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS INTENDED FOR TREATMENT OF TYPE I SUITERS, CREAM
ATE399156T1 (en) 2004-10-27 2008-07-15 Hoffmann La Roche NEW INDOLE OR BENZIMIDAZOLE DERIVATIVES
JP4675969B2 (en) 2004-11-09 2011-04-27 エフ．ホフマン−ラ ロシュ アーゲー Dibenzosuberone derivatives
DK1868999T3 (en) 2005-04-06 2009-08-17 Hoffmann La Roche Pyridine-3-carboxamide derivatives as reverse CB1 agonists
US7906652B2 (en) 2005-11-28 2011-03-15 Merck Sharp & Dohme Corp. Heterocycle-substituted 3-alkyl azetidine derivatives
US20080027087A1 (en) * 2006-02-21 2008-01-31 Ampla Pharmaceuticals, Inc. CB1 antagonists and inverse agonists
WO2007110449A1 (en) * 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
WO2007118853A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and their use as blockers of calcium channels
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
US7629346B2 (en) 2006-06-19 2009-12-08 Hoffmann-La Roche Inc. Pyrazinecarboxamide derivatives as CB1 antagonists
AR061606A1 (en) * 2006-06-22 2008-09-10 Medichem Sa SOLID FORMS OF RIMONABANT AND PROCESSES FOR PREPARATION
WO2008026219A2 (en) * 2006-09-01 2008-03-06 Hetero Drugs Limited Novel polymorphs of rimonabant
US7781593B2 (en) 2006-09-14 2010-08-24 Hoffmann-La Roche Inc. 5-phenyl-nicotinamide derivatives
MX2009002888A (en) * 2006-09-25 2009-03-31 Boehringer Ingelheim Int Compounds which modulate the cb2 receptor.
DE102007002260A1 (en) 2007-01-16 2008-07-31 Sanofi-Aventis Use of substituted pyranonic acid derivatives for the preparation of medicaments for the treatment of the metabolic syndrome
EP1953144A1 (en) * 2007-01-30 2008-08-06 Sandoz AG Novel polymorphic forms of N-piperidino-5-(4-chlorophenyl)-1-(2, 4-dichlorphenyl)-4-methyl-3-pyrazolecarboxamide
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
KR20100098563A (en) * 2007-12-18 2010-09-07 사노피-아벤티스 Azetidine derivatives, their preparation and their application in therapy
WO2010079241A1 (en) 2009-01-12 2010-07-15 Fundacion Hospital Nacional De Paraplejicos Para La Investigacion Y La Integracion Use of antagonists and/or inverse agonists of cb1 receptors for the preparation of drugs that increase motor neuron excitability
BRPI0902481B8 (en) 2009-07-31 2021-05-25 Soc Beneficente De Senhoras Hospital Sirio Libanes pharmaceutical composition comprising hemopressin and its use.
US8410107B2 (en) 2010-10-15 2013-04-02 Hoffmann-La Roche Inc. N-pyridin-3-yl or N-pyrazin-2-yl carboxamides
US8669254B2 (en) 2010-12-15 2014-03-11 Hoffman-La Roche Inc. Pyridine, pyridazine, pyrimidine or pyrazine carboxamides as HDL-cholesterol raising agents

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE61928B1 (en) † 1988-11-29 1994-11-30 Boots Co Plc Treatment of obesity
JPH04360167A (en) * 1991-06-06 1992-12-14 Mitsubishi Kasei Corp Proximity electrifier
FR2713225B1 (en) † 1993-12-02 1996-03-01 Sanofi Sa Substituted N-piperidino-3-pyrazolecarboxamide.
JPH07209959A (en) * 1994-01-24 1995-08-11 Ricoh Co Ltd Electrostatic charging device
US5596106A (en) † 1994-07-15 1997-01-21 Eli Lilly And Company Cannabinoid receptor antagonists
FR2735774B1 (en) * 1995-06-21 1997-09-12 Sanofi Sa USE OF HUMAN CB2 RECEPTOR AGONIST COMPOUNDS FOR THE PREPARATION OF IMMUNOMODULATORY DRUGS, NOVEL CB2 RECEPTOR AGONIST COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US6482927B1 (en) * 1995-11-27 2002-11-19 Millennium Pharmaceuticals, Inc. Chimeric proteins comprising the extracellular domain of murine Ob receptor
GB9619961D0 (en) * 1996-09-25 1996-11-13 Knoll Ag Medical treatment
EP0969852A4 (en) † 1996-10-31 2004-05-06 Merck & Co Inc Combination therapy for the treatment of diabetes and obesity
FR2758723B1 (en) † 1997-01-28 1999-04-23 Sanofi Sa USE OF CENTRAL CANNABINOID RECEPTOR ANTAGONISTS FOR THE PREPARATION OF DRUGS
US6207005B1 (en) * 1997-07-29 2001-03-27 Silicon Genesis Corporation Cluster tool apparatus using plasma immersion ion implantation
EP0920864A1 (en) † 1997-12-03 1999-06-09 Pfizer Products Inc. Combination therapy including a specific beta-3 agonist and an anorectic agent
FR2783246B1 (en) * 1998-09-11 2000-11-17 Aventis Pharma Sa AZETIDINE DERIVATIVES, THEIR PREPARATION AND THE MEDICINES CONTAINING THEM
KR100652994B1 (en) † 1998-09-11 2006-11-30 아방티 파르마 소시에테 아노님 Azetidine derivatives, preparation and medicines containing them
FR2805810B1 (en) * 2000-03-03 2002-04-26 Aventis Pharma Sa PHARMACEUTICAL COMPOSITIONS CONTAINING 3- AMINO-AZETIDINE DERIVATIVES, THE NEW DERIVATIVES AND THEIR PREPARATION
FR2805817B1 (en) * 2000-03-03 2002-04-26 Aventis Pharma Sa PHARMACEUTICAL COMPOSITIONS CONTAINING AZETIDINE DERIVATIVES, NOVEL AZETIDINE DERIVATIVES AND THEIR PREPARATION

Also Published As

Publication number Publication date
CN1473040A (en) 2004-02-04
DK1328269T4 (en) 2008-11-24
PT1328269E (en) 2004-08-31
YU26103A (en) 2006-08-17
JP2004512279A (en) 2004-04-22
DE60103556T3 (en) 2009-04-09
NO20031521D0 (en) 2003-04-03
SI1328269T1 (en) 2004-10-31
CN100409845C (en) 2008-08-13
NO20031521L (en) 2003-04-24
JP4221221B2 (en) 2009-02-12
AU9393601A (en) 2002-04-15
CA2424934A1 (en) 2002-04-11
DE60103556D1 (en) 2004-07-01
HUP0302044A3 (en) 2005-05-30
DK1328269T5 (en) 2009-03-16
EP1328269B1 (en) 2004-05-26
DE60103556T2 (en) 2005-06-30
BG107739A (en) 2004-01-30
HRP20030249A2 (en) 2005-02-28
AU2001293936B2 (en) 2007-01-25
HUP0302044A2 (en) 2003-11-28
DK1328269T3 (en) 2004-09-20
EA005924B1 (en) 2005-08-25
WO2002028346A3 (en) 2002-08-29
ATE267595T1 (en) 2004-06-15
TR200401264T4 (en) 2004-07-21
WO2002028346A2 (en) 2002-04-11
EE200300121A (en) 2005-04-15
NZ524904A (en) 2004-11-26
BR0114410A (en) 2004-02-17
EP1328269A2 (en) 2003-07-23
EP1328269B2 (en) 2008-07-30
PL362833A1 (en) 2004-11-02
EA200300441A1 (en) 2003-08-28
SI1328269T2 (en) 2008-12-31
FR2814678B1 (en) 2002-12-20
ES2217191T5 (en) 2009-02-16
ZA200303015B (en) 2004-02-26
KR20030036885A (en) 2003-05-09
SK4032003A3 (en) 2003-09-11
MXPA03002845A (en) 2004-09-10
FR2814678A1 (en) 2002-04-05
ES2217191T3 (en) 2004-11-01

Similar Documents

Publication Publication Date Title
AU9393601A (en) Association of the cb1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity
AU2001293936A1 (en) Association of the CB1 receptor antagonist and sibutramin, for treating obesity
AP1718A (en) 3-(4-amidopyrrol-2-ylmethlidene)-2-indolinone derivatives as protein kinase inhibitors
AU3652102A (en) Compounds and their uses
HUP0401924A3 (en) Cannabinoid receptor ligands, their use and pharmaceutical compositions containing them
HUP0304060A3 (en) Cannabinoid receptor ligands, their use and pharmaceutical compositions containing them
HUP0301745A3 (en) Cyclopentanoindoles, compositions containing such compounds and their use
MXPA02012891A (en) Pharmaceutical compositions of estrogenic agents.
HUP0302578A3 (en) Isoindole-imide compounds, compositions containing them, and use thereof
AP1830A (en) Polymorphous form of rimonabant, preparation method and pharmaceutical compositions containing same.
HUP0402003A3 (en) Substituted 1,4-benzodiazepines, pharmaceutical compositions containing them and uses thereof
WO2002064125A3 (en) Use of a farnesoid x receptor antagonist for treating hyperlipidemia
IL157065A0 (en) 2h-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof
BG105277A (en) Prevention of migraine recurrence
MXPA03003892A (en) Bombesin receptor antagonists.
IL152243A0 (en) Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
MXPA03004414A (en) Bombesin receptor antagonists.
HK1033876A1 (en) Use of nmda antagonists for treatment of irritablebowel syndrome.
DE60212130D1 (en) Carvedilolpolymorph
RS47804A (en) 1,3-diarylprop-2-en-1-ones, compositions containing same and use thereof
AU2002306956A1 (en) Delta opioid receptor disruptions, compositions and methods related thereto
PL365470A1 (en) Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
IT1317742B1 (en) New compositions useful for controlled release of metamizol and tramadol