DK1328269T5 - Combination of a CB1 receptor antagonist and sibutramine for the treatment of obesity - Google Patents

Combination of a CB1 receptor antagonist and sibutramine for the treatment of obesity

Info

Publication number
DK1328269T5
DK1328269T5 DK01974413T DK01974413T DK1328269T5 DK 1328269 T5 DK1328269 T5 DK 1328269T5 DK 01974413 T DK01974413 T DK 01974413T DK 01974413 T DK01974413 T DK 01974413T DK 1328269 T5 DK1328269 T5 DK 1328269T5
Authority
DK
Denmark
Prior art keywords
receptor antagonist
obesity
sibutramine
treatment
combination
Prior art date
Application number
DK01974413T
Other languages
Danish (da)
Other versions
DK1328269T4 (en
DK1328269T3 (en
Inventor
Odile Piot-Grosjean
Philippe Picaut
Francois Petitet
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8854974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1328269(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK1328269T3 publication Critical patent/DK1328269T3/en
Publication of DK1328269T4 publication Critical patent/DK1328269T4/en
Publication of DK1328269T5 publication Critical patent/DK1328269T5/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The invention concerns the association of the CB1 receptor antagonist and a sibutramin, pharmaceutical compositions containing same and use thereof for treating obesity.
DK01974413T 2000-10-04 2001-10-01 Combination of a CB1 receptor antagonist and sibutramine for the treatment of obesity DK1328269T5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0012646A FR2814678B1 (en) 2000-10-04 2000-10-04 COMBINATION OF AN ANTAGONIST OF THE CB1 RECEPTOR AND SIBUTRAMINE, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE TREATMENT OF OBESITY
PCT/FR2001/003022 WO2002028346A2 (en) 2000-10-04 2001-10-01 Association of the cb1 receptor antagonist and sibutramin, for treating obesity

Publications (3)

Publication Number Publication Date
DK1328269T3 DK1328269T3 (en) 2004-09-20
DK1328269T4 DK1328269T4 (en) 2008-11-24
DK1328269T5 true DK1328269T5 (en) 2009-03-16

Family

ID=8854974

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01974413T DK1328269T5 (en) 2000-10-04 2001-10-01 Combination of a CB1 receptor antagonist and sibutramine for the treatment of obesity

Country Status (29)

Country Link
EP (1) EP1328269B2 (en)
JP (1) JP4221221B2 (en)
KR (1) KR20030036885A (en)
CN (1) CN100409845C (en)
AT (1) ATE267595T1 (en)
AU (2) AU9393601A (en)
BG (1) BG107739A (en)
BR (1) BR0114410A (en)
CA (1) CA2424934A1 (en)
DE (1) DE60103556T3 (en)
DK (1) DK1328269T5 (en)
EA (1) EA005924B1 (en)
EE (1) EE200300121A (en)
ES (1) ES2217191T5 (en)
FR (1) FR2814678B1 (en)
HR (1) HRP20030249A2 (en)
HU (1) HUP0302044A3 (en)
IL (1) IL155236A0 (en)
MX (1) MXPA03002845A (en)
NO (1) NO20031521L (en)
NZ (1) NZ524904A (en)
PL (1) PL362833A1 (en)
PT (1) PT1328269E (en)
SI (1) SI1328269T2 (en)
SK (1) SK4032003A3 (en)
TR (1) TR200401264T4 (en)
WO (1) WO2002028346A2 (en)
YU (1) YU26103A (en)
ZA (1) ZA200303015B (en)

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US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
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EP1498123A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Emulsifying systems containing azetidine derivatives
EP1663215A1 (en) * 2003-09-02 2006-06-07 Solvay Pharmaceuticals GmbH Novel medical use of selective cb1- receptor antagonists
FR2861303A1 (en) * 2003-10-24 2005-04-29 Sanofi Synthelabo Use of pyrazole derivative as cannabinoid CB1 receptor antagonist, for treatment and prevention of metabolic syndrome, particularly cardiovascular risks, dyslipidemia and liver disease associated with obesity
WO2005049615A1 (en) * 2003-11-21 2005-06-02 Pfizer Products Inc. Pyrazolo`1,5-a!`1,3,5! triazin -4-one derivatives as cb1 receptor antagonists
WO2005058887A1 (en) 2003-12-08 2005-06-30 F. Hoffmann-La Roche Ag Novel thiazole derivates
BRPI0507120A (en) 2004-01-28 2007-06-19 Hoffmann La Roche compounds, process for the manufacture thereof, pharmaceutical compositions comprising them, method for treating and / or prophylaxis of diseases that are associated with cb1 receptor modulation and their use
EP1749002B1 (en) 2004-05-10 2009-05-27 F.Hoffmann-La Roche Ag Pyrrole or imidazole amides for treating obesity
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
WO2006039334A1 (en) * 2004-09-29 2006-04-13 Schering Corporation Combinations of substituted azetidonones and cb1 antagonists
FR2876689B1 (en) * 2004-10-14 2008-02-22 Aventis Pharma Sa NOVEL PROCESS AND INTERMEDIATES FOR PREPARING N- (1-BENZHYDRYL-AZETIDIN-3-YL) -N-PHENYL-METHYLSULFONAMIDE DERIVATIVES
RU2007119315A (en) 2004-10-25 2008-11-27 Зольвай Фармасьютиклз Гмбх (De) PHARMACEUTICAL COMPOSITIONS CONTAINING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS INTENDED FOR TREATMENT OF TYPE I SUITERS, CREAM
ATE399156T1 (en) 2004-10-27 2008-07-15 Hoffmann La Roche NEW INDOLE OR BENZIMIDAZOLE DERIVATIVES
JP4675969B2 (en) 2004-11-09 2011-04-27 エフ．ホフマン−ラ ロシュ アーゲー Dibenzosuberone derivatives
DK1868999T3 (en) 2005-04-06 2009-08-17 Hoffmann La Roche Pyridine-3-carboxamide derivatives as reverse CB1 agonists
US7906652B2 (en) 2005-11-28 2011-03-15 Merck Sharp & Dohme Corp. Heterocycle-substituted 3-alkyl azetidine derivatives
US20080027087A1 (en) * 2006-02-21 2008-01-31 Ampla Pharmaceuticals, Inc. CB1 antagonists and inverse agonists
WO2007110449A1 (en) * 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
WO2007118853A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and their use as blockers of calcium channels
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
US7629346B2 (en) 2006-06-19 2009-12-08 Hoffmann-La Roche Inc. Pyrazinecarboxamide derivatives as CB1 antagonists
AR061606A1 (en) * 2006-06-22 2008-09-10 Medichem Sa SOLID FORMS OF RIMONABANT AND PROCESSES FOR PREPARATION
WO2008026219A2 (en) * 2006-09-01 2008-03-06 Hetero Drugs Limited Novel polymorphs of rimonabant
US7781593B2 (en) 2006-09-14 2010-08-24 Hoffmann-La Roche Inc. 5-phenyl-nicotinamide derivatives
MX2009002888A (en) * 2006-09-25 2009-03-31 Boehringer Ingelheim Int Compounds which modulate the cb2 receptor.
DE102007002260A1 (en) 2007-01-16 2008-07-31 Sanofi-Aventis Use of substituted pyranonic acid derivatives for the preparation of medicaments for the treatment of the metabolic syndrome
EP1953144A1 (en) * 2007-01-30 2008-08-06 Sandoz AG Novel polymorphic forms of N-piperidino-5-(4-chlorophenyl)-1-(2, 4-dichlorphenyl)-4-methyl-3-pyrazolecarboxamide
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
KR20100098563A (en) * 2007-12-18 2010-09-07 사노피-아벤티스 Azetidine derivatives, their preparation and their application in therapy
WO2010079241A1 (en) 2009-01-12 2010-07-15 Fundacion Hospital Nacional De Paraplejicos Para La Investigacion Y La Integracion Use of antagonists and/or inverse agonists of cb1 receptors for the preparation of drugs that increase motor neuron excitability
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Also Published As

Publication number Publication date
CN1473040A (en) 2004-02-04
DK1328269T4 (en) 2008-11-24
PT1328269E (en) 2004-08-31
YU26103A (en) 2006-08-17
JP2004512279A (en) 2004-04-22
DE60103556T3 (en) 2009-04-09
NO20031521D0 (en) 2003-04-03
SI1328269T1 (en) 2004-10-31
CN100409845C (en) 2008-08-13
NO20031521L (en) 2003-04-24
JP4221221B2 (en) 2009-02-12
AU9393601A (en) 2002-04-15
IL155236A0 (en) 2003-11-23
CA2424934A1 (en) 2002-04-11
DE60103556D1 (en) 2004-07-01
HUP0302044A3 (en) 2005-05-30
EP1328269B1 (en) 2004-05-26
DE60103556T2 (en) 2005-06-30
BG107739A (en) 2004-01-30
HRP20030249A2 (en) 2005-02-28
AU2001293936B2 (en) 2007-01-25
HUP0302044A2 (en) 2003-11-28
DK1328269T3 (en) 2004-09-20
EA005924B1 (en) 2005-08-25
WO2002028346A3 (en) 2002-08-29
ATE267595T1 (en) 2004-06-15
TR200401264T4 (en) 2004-07-21
WO2002028346A2 (en) 2002-04-11
EE200300121A (en) 2005-04-15
NZ524904A (en) 2004-11-26
BR0114410A (en) 2004-02-17
EP1328269A2 (en) 2003-07-23
EP1328269B2 (en) 2008-07-30
PL362833A1 (en) 2004-11-02
EA200300441A1 (en) 2003-08-28
SI1328269T2 (en) 2008-12-31
FR2814678B1 (en) 2002-12-20
ES2217191T5 (en) 2009-02-16
ZA200303015B (en) 2004-02-26
KR20030036885A (en) 2003-05-09
SK4032003A3 (en) 2003-09-11
MXPA03002845A (en) 2004-09-10
FR2814678A1 (en) 2002-04-05
ES2217191T3 (en) 2004-11-01

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