IL154608A0 - Vaccine - Google Patents

Vaccine

Info

Publication number
IL154608A0
IL154608A0 IL15460801A IL15460801A IL154608A0 IL 154608 A0 IL154608 A0 IL 154608A0 IL 15460801 A IL15460801 A IL 15460801A IL 15460801 A IL15460801 A IL 15460801A IL 154608 A0 IL154608 A0 IL 154608A0
Authority
IL
Israel
Prior art keywords
antigen
vaccines
relates
present
pneumococcal polysaccharide
Prior art date
Application number
IL15460801A
Other languages
English (en)
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9899575&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL154608(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of IL154608A0 publication Critical patent/IL154608A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0208Specific bacteria not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/125Picornaviridae, e.g. calicivirus
    • A61K39/13Poliovirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL15460801A 2000-09-15 2001-09-12 Vaccine IL154608A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0022742.1A GB0022742D0 (en) 2000-09-15 2000-09-15 Vaccine
PCT/EP2001/010570 WO2002022168A2 (en) 2000-09-15 2001-09-12 Vaccine against streptococcus pneumoniae

Publications (1)

Publication Number Publication Date
IL154608A0 true IL154608A0 (en) 2003-09-17

Family

ID=9899575

Family Applications (4)

Application Number Title Priority Date Filing Date
IL15460801A IL154608A0 (en) 2000-09-15 2001-09-12 Vaccine
IL15460701A IL154607A0 (en) 2000-09-15 2001-09-12 Vaccine
IL154607A IL154607A (en) 2000-09-15 2003-02-24 Training compounds containing at least one antigenic polysaccharide of strepococcus pneumoniae and at least one antigenic protein of strepococcus pneumoniae and vaccine containing them
IL154608A IL154608A (en) 2000-09-15 2003-02-24 Effective compound compounds for the prevention or amelioration of pneumonia infection containing at least two streptococcal pneumonia proteins and possibly hemophilus protein.

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL15460701A IL154607A0 (en) 2000-09-15 2001-09-12 Vaccine
IL154607A IL154607A (en) 2000-09-15 2003-02-24 Training compounds containing at least one antigenic polysaccharide of strepococcus pneumoniae and at least one antigenic protein of strepococcus pneumoniae and vaccine containing them
IL154608A IL154608A (en) 2000-09-15 2003-02-24 Effective compound compounds for the prevention or amelioration of pneumonia infection containing at least two streptococcal pneumonia proteins and possibly hemophilus protein.

Country Status (24)

Country Link
US (5) US20040081662A1 (cs)
EP (6) EP2314313B1 (cs)
JP (3) JP4880184B2 (cs)
KR (5) KR20100091241A (cs)
CN (3) CN1253205C (cs)
AT (1) ATE516815T1 (cs)
AU (4) AU3819302A (cs)
BR (2) BR0113822A (cs)
CA (2) CA2422002C (cs)
CY (1) CY1111915T1 (cs)
CZ (2) CZ305343B6 (cs)
DK (1) DK1317279T3 (cs)
ES (4) ES2551097T3 (cs)
GB (1) GB0022742D0 (cs)
HU (2) HUP0301092A3 (cs)
IL (4) IL154608A0 (cs)
MX (2) MXPA03002264A (cs)
NO (2) NO337730B1 (cs)
NZ (2) NZ524287A (cs)
PL (2) PL210198B1 (cs)
PT (1) PT1317279E (cs)
SI (1) SI1317279T1 (cs)
WO (2) WO2002022167A2 (cs)
ZA (2) ZA200301524B (cs)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US7129340B1 (en) 1997-07-02 2006-10-31 sanofi pasteur limited/sanofi pasteur limitée Nucleic acid and amino acid sequences relating to streptococcus pneumoniae for diagnostics and therapeutics
US6800744B1 (en) 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US20010016200A1 (en) 1998-04-23 2001-08-23 Briles David E. Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US7128918B1 (en) * 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
WO2000056358A2 (en) * 1999-03-19 2000-09-28 Smithkline Beecham Biologicals S.A. Vaccine against streptococcus pneumoniae capsular polysaccharides
US7074415B2 (en) * 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
WO2003054007A2 (en) 2001-12-20 2003-07-03 Shire Biochem Inc. Streptococcus antigens
US8691243B2 (en) 2002-04-02 2014-04-08 Ben-Gurion University Of The Negev Research And Development Authority Protein-based Streptococcus pneumoniae vaccine
EP2275122A3 (en) * 2002-04-02 2011-05-18 Ben Gurion University Of The Negev Research And Development Authority Protein-based streptococcus pneumoniae vaccines
ES2608048T3 (es) 2002-10-11 2017-04-05 Glaxosmithkline Biologicals Sa Vacunas polipeptídicas para protección amplia contra linajes meningocócicos hipervirulentos
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
US8229903B2 (en) * 2002-12-19 2012-07-24 International Business Machines Corporation Suggesting data interpretations and patterns for updating policy documents
PT2191844E (pt) * 2003-01-30 2014-06-04 Novartis Ag Vacinas injetáveis contra múltiplos serogrupos meningocócicos
NZ541969A (en) 2003-03-13 2008-01-31 Glaxosmithkline Biolog Sa Purifying pneumolysin from Streptococcus pneumoniae in a single chromatographic step by binding it to a hydrophobic interaction column in the presence of detergent and high salt
EP1477802A1 (en) * 2003-05-16 2004-11-17 Erasmus Universiteit Rotterdam Method for selecting and producing vaccine components and vaccines based thereon
DE602004032481D1 (de) 2003-10-02 2011-06-09 Novartis Vaccines & Diagnostic Kombinationsimpfstoffe gegen Meningitis
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
KR20070095868A (ko) * 2004-09-21 2007-10-01 사노피 파스퇴르 인크 다가 수막구균 유도체화된 다당류-단백질 접합체 및 백신
AU2011253684B8 (en) * 2005-04-08 2013-07-11 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
KR102564388B1 (ko) * 2005-04-08 2023-08-08 와이어쓰 엘엘씨 다가 폐렴구균 다당류-단백질 접합체 조성물
GB0522765D0 (en) 2005-11-08 2005-12-14 Chiron Srl Combination vaccine manufacture
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
EP3017827B1 (en) 2005-12-22 2018-11-07 GlaxoSmithKline Biologicals s.a. Pneumococcal polysaccharide conjugate vaccine
DK1976974T3 (da) * 2005-12-28 2014-09-15 Uab Research Foundation Pneumokok-serotyper.
US8808707B1 (en) 2006-05-08 2014-08-19 Wyeth Llc Pneumococcal dosing regimen
US20110002962A1 (en) * 2006-08-17 2011-01-06 The Uab Research Foundation Immunogenic PcpA Polypeptides and Uses Thereof
UY31101A1 (es) * 2007-05-24 2009-01-05 Glaxosmithkline Biologicals Sa Composición antigénica liofilizada
JP5489993B2 (ja) 2007-06-26 2014-05-14 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 肺炎連鎖球菌莢膜多糖コンジュゲートを含むワクチン
GB0713880D0 (en) 2007-07-17 2007-08-29 Novartis Ag Conjugate purification
US20160228500A9 (en) * 2007-07-23 2016-08-11 Martina Ochs Immunogenic Polypeptides and Monoclonal Antibodies
BRPI0814127A2 (pt) 2007-07-23 2015-02-03 Sanofi Pasteur Ltd Polipeptídeos imunegênicos e anticorpos monoclonais
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
EP2225265A2 (en) * 2007-09-14 2010-09-08 Katholieke Universiteit Leuven Streptococcus pneumoniae vaccines
CN105044337A (zh) * 2008-02-01 2015-11-11 圣诺菲·帕斯图尔有限公司 用于诊断肺炎链球菌的试验
MY150481A (en) 2008-03-03 2014-01-30 Irm Llc Compounds and compositions as tlr activity modulators
RU2555757C2 (ru) 2009-03-24 2015-07-10 Новартис Аг Комбинации менингококкового фактор н-связывающего белка и пневмококковых сахаридных конъюгатов
US9517263B2 (en) 2009-06-10 2016-12-13 Glaxosmithkline Biologicals Sa Benzonaphthyridine-containing vaccines
TWI445708B (zh) 2009-09-02 2014-07-21 Irm Llc 作為tlr活性調節劑之化合物及組合物
EP2459216B1 (en) 2009-09-02 2013-10-30 Novartis AG Immunogenic compositions including tlr activity modulators
AU2010293902A1 (en) 2009-09-10 2012-03-22 Novartis Ag Combination vaccines against respiratory tract diseases
CN101690810B (zh) * 2009-10-21 2011-08-17 辽宁益康生物股份有限公司 一种鸡新城疫、传染性支气管炎、减蛋综合征、禽流感四联灭活疫苗佐剂及其制备方法
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
CA2784580A1 (en) 2009-12-15 2011-07-14 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
CA2784447A1 (en) 2009-12-22 2011-06-30 Sanofi Pasteur Limited Adjuvanted immunogenic compositions and related methods
EP2515938A4 (en) * 2009-12-22 2013-08-28 Sanofi Pasteur Ltd IMMUNOGENIC COMPOSITIONS
GB201003922D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Conjugation process
GB201003920D0 (en) * 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
MX341395B (es) 2010-03-23 2016-08-18 Novartis Ag * Compuestos (lipopeptidos basados en cisteina) y composiciones como agonistas de tlr2 usados para el tratamiento de infecciones, inflamaciones, enfermedades respiratorias, etc.
WO2012072769A1 (en) 2010-12-01 2012-06-07 Novartis Ag Pneumococcal rrgb epitopes and clade combinations
AU2011336366B2 (en) * 2010-12-03 2016-05-12 Sanofi Pasteur Limited Composition for immunization against Streptococcus pneumoniae
EP2709658A1 (en) * 2011-05-17 2014-03-26 GlaxoSmithKline Biologicals SA Vaccine against streptococcus pneumoniae
JP2015510872A (ja) 2012-03-07 2015-04-13 ノバルティス アーゲー Streptococcuspneumoniae抗原の増強された製剤
JP2014000016A (ja) * 2012-06-15 2014-01-09 National Agriculture & Food Research Organization 豚丹毒菌の新規な抗原タンパク質、その遺伝子、及び組換えベクターとその利用
RU2510281C2 (ru) * 2012-06-22 2014-03-27 Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА
BR112015008418A2 (pt) * 2012-10-17 2017-07-04 Glaxosmithkline Biologicals Sa uso de uma composição imunogênica, composição imunogênica, e, métodos para intensificar atividade opsônica mediada por anticorpo contra um sorotipo alvejado de streptococcus pneumoniae em um indivíduo e para imunizar um hospedeiro humano contra doenças causadas por infecção por streptococcus pneumoniae
GB201218660D0 (en) 2012-10-17 2012-11-28 Glaxosmithkline Biolog Sa Immunogenic composition
EP2941349B1 (en) 2013-01-01 2017-07-19 AGFA Graphics NV (ethylene, vinyl acetal) copolymers and their use in lithographic printing plate precursors
CN105188747A (zh) 2013-02-01 2015-12-23 葛兰素史密斯克莱生物公司 包含toll样受体激动剂的免疫组合物的皮内递送
US11160855B2 (en) 2014-01-21 2021-11-02 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
WO2015183676A1 (en) * 2014-05-29 2015-12-03 Kapre Subhash V Synthetic peptides as carriers for conjugation with polysaccharides
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
CN108778746A (zh) 2016-03-16 2018-11-09 爱克发有限公司 加工平版印刷版的方法
US11844829B2 (en) 2016-12-28 2023-12-19 Zalvac Ab Microparticles from Streptococcus pneumoniae as vaccine antigens
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
US10688170B2 (en) 2017-06-10 2020-06-23 Inventprise, Llc Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
SG11202007688YA (en) 2018-02-12 2020-09-29 Inimmune Corp Toll-like receptor ligands
JP2022525333A (ja) * 2019-03-13 2022-05-12 セント・ジュード・チルドレンズ・リサーチ・ホスピタル 肺炎連鎖球菌の伝染を低減させるためのワクチン組成物および方法
EP3778253A1 (en) 2019-08-13 2021-02-17 Agfa Nv Method for processing a lithographic printing plate
US12053515B2 (en) 2020-08-10 2024-08-06 Inventprise, Inc. Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24F
KR20230098825A (ko) 2020-11-04 2023-07-04 엘리고 바이오사이언스 씨. 아크네스 개체군에게 dna 페이로드의 원위치 전달을 위한 파지-유래 입자
WO2024239063A1 (en) * 2023-05-22 2024-11-28 Gpn Vaccines Pty Ltd Modified streptococcal immunogen and uses thereof

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235877A (en) 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4372945A (en) 1979-11-13 1983-02-08 Likhite Vilas V Antigen compounds
IL61904A (en) 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
BE889979A (fr) 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US5360897A (en) * 1981-08-31 1994-11-01 The University Of Rochester Immunogenic conjugates of streptococcus pneumonial capsular polymer and toxin or in toxiad
US4761283A (en) * 1983-07-05 1988-08-02 The University Of Rochester Immunogenic conjugates
US4882317A (en) * 1984-05-10 1989-11-21 Merck & Co., Inc. Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4709017A (en) 1985-06-07 1987-11-24 President And Fellows Of Harvard College Modified toxic vaccines
US5173294A (en) 1986-11-18 1992-12-22 Research Foundation Of State University Of New York Dna probe for the identification of haemophilus influenzae
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US5339163A (en) 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5006914A (en) * 1988-12-02 1991-04-09 Advanced Technology Materials, Inc. Single crystal semiconductor substrate articles and semiconductor devices comprising same
ATE205534T1 (de) 1988-12-16 2001-09-15 Nederlanden Staat Pneumolysin-mutanten und pneumokokken-impfstoffe daraus
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
SE466259B (sv) 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
CA2059693C (en) 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US6592876B1 (en) 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
US5980909A (en) * 1991-02-15 1999-11-09 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
US5476929A (en) 1991-02-15 1995-12-19 Uab Research Foundation Structural gene of pneumococcal protein
DE69226167T2 (de) 1991-02-15 1998-11-12 The Uab Research Foundation, Birmingham, Alabama Strukturgen von pneumokokken-protein
US5552146A (en) 1991-08-15 1996-09-03 Board Of Regents, The University Of Texas System Methods and compositions relating to useful antigens of Moraxella catarrhalis
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
US5371197A (en) * 1991-09-24 1994-12-06 Merck & Co., Inc. Protein-dimeric polysaccharide conjugate vaccine
EP0652758B1 (en) 1992-06-18 2000-01-05 The President And Fellows Of Harvard College Diphtheria toxin vaccines
DE69313134T2 (de) 1992-06-25 1998-02-26 Smithkline Beecham Biolog Adjuvantien enthaltende impfstoffzusammensetzung
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
ATE211654T1 (de) * 1992-09-16 2002-01-15 Univ Tennessee Res Corp Antigene des hybriden m-proteins und träger für gruppe a streptokokkenimpfstoff
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
GB9224584D0 (en) 1992-11-23 1993-01-13 Connaught Lab Use of outer membrane protein d15 and its peptides as vaccine against haempohilus influenzae diseases
ES2162139T5 (es) 1993-03-23 2008-05-16 Smithkline Beecham Biologicals S.A. Composiciones de vacuna que contienen monofosforil-lipido a 3-o-desacilado.
DE69431624T2 (de) 1993-05-18 2003-07-10 The Ohio State University Research Foundation, Columbus Impfstoff gegen mittelohrentzündung
KR100376361B1 (ko) 1993-09-22 2003-07-18 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신 면역원성구조체의제조를위하여신규한시아닐레이팅시약을사용하여용해성탄수화물을활성화하는방법
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
WO1995024176A1 (en) 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5866135A (en) * 1994-04-21 1999-02-02 North American Vaccine, Inc. Group A streptococcal polysaccharide immunogenic compositions and methods
US5917017A (en) 1994-06-08 1999-06-29 President And Fellows Of Harvard College Diphtheria toxin vaccines bearing a mutated R domain
AU713040B2 (en) 1994-07-15 1999-11-18 University Of Iowa Research Foundation, The Immunomodulatory oligonucleotides
US5565204A (en) 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
US6440425B1 (en) 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US5843464A (en) 1995-06-02 1998-12-01 The Ohio State University Synthetic chimeric fimbrin peptides
EA199800046A1 (ru) 1995-06-07 1998-06-25 Байокем Вэксинс Инк. Полипептид, последовательность днк, вакцинная композиция (варианты), антитело или его фрагмент, вакцина, применения указанных полипептида, последовательности днк и антитела или его фрагмента
GB9513074D0 (en) 1995-06-27 1995-08-30 Cortecs Ltd Novel anigen
US6290970B1 (en) 1995-10-11 2001-09-18 Aventis Pasteur Limited Transferrin receptor protein of Moraxella
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US6090576A (en) 1996-03-08 2000-07-18 Connaught Laboratories Limited DNA encoding a transferrin receptor of Moraxella
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
US6245335B1 (en) * 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
JP2000511411A (ja) * 1996-05-01 2000-09-05 ザ ロックフェラー ユニヴァーシティ 抗―肺炎球菌ワクチン用のコリン結合タンパク質
US5744417A (en) 1996-05-02 1998-04-28 Lyondell Petrochemical Company Supported catalyst
US7341727B1 (en) 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
JP4012252B2 (ja) 1996-06-18 2007-11-21 アルザ コーポレイション 薬剤の経皮放出又はサンプリングを高めるための装置
EP0956289A4 (en) 1996-08-16 2004-10-13 Smithkline Beecham Corp NOVEL PROKARYOTA POLYNUCLEOTIDES AND POLYPEPTIDES AND USES THEREOF
US5882871A (en) 1996-09-24 1999-03-16 Smithkline Beecham Corporation Saliva binding protein
US5882896A (en) 1996-09-24 1999-03-16 Smithkline Beecham Corporation M protein
CA2271720A1 (en) 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
US6291654B1 (en) 1996-11-12 2001-09-18 Regents Of The University Of Minnesota Method for isolating a C3 binding protein of streptococcus pneumoniae
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
CN1133472C (zh) 1996-12-20 2004-01-07 阿尔萨公司 增加经皮样剂流量的装置
DE19708537A1 (de) 1997-03-03 1998-09-10 Biotechnolog Forschung Gmbh Neues Oberflächenprotein (SpsA-Protein) von Streptococcus pneumoniae etc.
FR2763244B1 (fr) * 1997-05-14 2003-08-01 Pasteur Merieux Serums Vacc Composition vaccinale multivalente a porteur mixte
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
WO1998055606A2 (en) 1997-06-03 1998-12-10 Connaught Laboratories Limited Lactoferrin receptor genes of moraxella
US6764686B2 (en) 1997-07-21 2004-07-20 Baxter International Inc. Modified immunogenic pneumolysin compositions as vaccines
US6224880B1 (en) * 1997-09-24 2001-05-01 Merck & Co., Inc. Immunization against Streptococcus pneumoniae using conjugated and unconjugated pneumoccocal polysaccharide vaccines
CA2305016A1 (en) 1997-09-24 1999-04-01 Regents Of The University Of Minnesota Human complement c3-degrading proteinase from streptococcus pneumoniae
EP0916726A1 (en) * 1997-11-13 1999-05-19 Rijksuniversiteit te Groningen Attaching substances to micro-organisms
EP1035867A1 (en) 1997-12-02 2000-09-20 Powderject Vaccines, Inc. Transdermal delivery of particulate vaccine compositions
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
US6709658B1 (en) * 1998-02-12 2004-03-23 Wyeth Holdings Corporation Pneumococcal vaccines formulated with interleukin-12
CA2326388C (en) 1998-04-07 2014-02-04 St. Jude Children's Research Hospital A polypeptide comprising the amino acid of an n-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
NZ530277A (en) 1998-04-07 2005-08-26 Medimmune Inc Derivatives of pneumococcal choline binding proteins for vaccines
AU770378B2 (en) 1998-04-23 2004-02-19 Uab Research Foundation Pneumococcal surface protein C(PspC), epitopic regions and strain selection thereof, and uses therefor
GB9812613D0 (en) 1998-06-11 1998-08-12 Smithkline Beecham Biolog Vaccine
EP1115875A1 (en) 1998-09-24 2001-07-18 Regents Of The University Of Minnesota Human complement c3-degrading polypeptide from streptococcus pneumoniae
AU1819400A (en) 1998-11-17 2000-06-05 Schlumberger Technology Corporation Transmitting information over a communication link
AU2027400A (en) 1998-11-19 2000-06-05 St. Jude Children's Research Hospital Identification and characterization of novel pneumococcal choline binding proteins, cbpg and cbpd, and diagnostic and therapeutic uses thereof
JP4689044B2 (ja) * 1998-12-21 2011-05-25 メディミューン,インコーポレーテッド ワクチン用の肺炎連鎖球菌タンパク質と免疫原断片
EP1034792A1 (en) * 1999-03-11 2000-09-13 Pasteur Merieux Serums Et Vaccins Intranasal delivery of pneumococcal polysaccharide vaccines
WO2000056358A2 (en) * 1999-03-19 2000-09-28 Smithkline Beecham Biologicals S.A. Vaccine against streptococcus pneumoniae capsular polysaccharides
ES2360296T3 (es) 1999-06-10 2011-06-02 Medimmune, Llc Vacunas y proteínas de setreptococcus pneumoniae.
BR0011478A (pt) * 1999-06-10 2002-03-19 Uab Research Foundation Composição de combinação imunológica, métodos de induzir uma resposta imunológica em um animal, e de imunizar um hospedeiro contra infecção pneumocócica, e, composição imunogênica para administração intranasal
US6319224B1 (en) 1999-08-20 2001-11-20 Bioject Medical Technologies Inc. Intradermal injection system for injecting DNA-based injectables into humans
US6494865B1 (en) 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly

Also Published As

Publication number Publication date
ZA200301524B (en) 2004-04-21
EP2305298A1 (en) 2011-04-06
NZ524286A (en) 2005-05-27
BR0113822A (pt) 2003-06-24
HUP0301092A3 (en) 2011-03-28
US20110008419A1 (en) 2011-01-13
WO2002022167A3 (en) 2002-06-27
ES2545876T3 (es) 2015-09-16
IL154608A (en) 2010-11-30
DK1317279T3 (da) 2011-10-24
EP2314313B1 (en) 2017-12-27
NO20031184L (no) 2003-05-14
NO20031184D0 (no) 2003-03-14
WO2002022167A2 (en) 2002-03-21
HUP0301043A3 (en) 2011-03-28
HK1057698A1 (en) 2004-04-16
SI1317279T1 (sl) 2011-11-30
EP2314313A1 (en) 2011-04-27
EP1317280B1 (en) 2015-07-15
EP1317279A2 (en) 2003-06-11
BR0113821A (pt) 2003-06-24
US20080081050A1 (en) 2008-04-03
IL154607A (en) 2010-11-30
EP2305297A1 (en) 2011-04-06
CA2421998A1 (en) 2002-03-21
HUP0301092A2 (hu) 2003-09-29
AU2002238193B2 (en) 2005-05-12
CN101502648B (zh) 2013-07-03
KR100805991B1 (ko) 2008-02-26
KR100991916B1 (ko) 2010-11-04
NO20031183D0 (no) 2003-03-14
ES2551097T3 (es) 2015-11-16
JP4880184B2 (ja) 2012-02-22
EP2140878B1 (en) 2015-08-26
KR20100091241A (ko) 2010-08-18
KR20110132483A (ko) 2011-12-07
WO2002022168A3 (en) 2002-06-27
NO337730B1 (no) 2016-06-13
US20040081662A1 (en) 2004-04-29
PL210198B1 (pl) 2011-12-30
NO336186B1 (no) 2015-06-08
NO20031183L (no) 2003-05-13
EP1317279B1 (en) 2011-07-20
CZ2003757A3 (cs) 2003-10-15
CN1253205C (zh) 2006-04-26
CY1111915T1 (el) 2015-11-04
CA2422002C (en) 2013-06-18
CN1477970A (zh) 2004-02-25
ZA200301526B (en) 2004-06-04
IL154607A0 (en) 2003-09-17
KR20030031187A (ko) 2003-04-18
CA2421998C (en) 2015-01-06
AU3819302A (en) 2002-03-26
JP4903975B2 (ja) 2012-03-28
WO2002022168A2 (en) 2002-03-21
US20060051361A1 (en) 2006-03-09
CN101502648A (zh) 2009-08-12
US20140099339A1 (en) 2014-04-10
KR20030031188A (ko) 2003-04-18
NZ524287A (en) 2005-03-24
AU2002220548B2 (en) 2005-04-14
PL361395A1 (en) 2004-10-04
CA2422002A1 (en) 2002-03-21
MXPA03002264A (es) 2004-12-03
EP1317280A2 (en) 2003-06-11
JP2012006969A (ja) 2012-01-12
PL209247B1 (pl) 2011-08-31
EP2140878A1 (en) 2010-01-06
KR101268790B1 (ko) 2013-05-29
CZ305343B6 (cs) 2015-08-12
JP2004508417A (ja) 2004-03-18
MXPA03002265A (es) 2004-12-03
AU2054802A (en) 2002-03-26
HUP0301043A2 (hu) 2003-09-29
KR20080080683A (ko) 2008-09-04
ES2659400T3 (es) 2018-03-15
PT1317279E (pt) 2011-10-11
CZ305324B6 (cs) 2015-08-05
ATE516815T1 (de) 2011-08-15
CN100486642C (zh) 2009-05-13
CN1694723A (zh) 2005-11-09
CZ2003756A3 (cs) 2003-10-15
ES2368902T3 (es) 2011-11-23
JP2004508416A (ja) 2004-03-18
PL361401A1 (en) 2004-10-04
GB0022742D0 (en) 2000-11-01

Similar Documents

Publication Publication Date Title
IL154607A0 (en) Vaccine
JP2004508417A5 (cs)
HK1043730A1 (zh) 抗肺炎鏈球菌莢膜多糖的疫菌
NZ505107A (en) Vaccine comprising CpG oligonucleotide and Streptococcus pnueumoniae antigen
JP2018531315A5 (cs)
RU2004117775A (ru) Вакцина steptococcus pneumoniae
AU1234697A (en) Streptococcus equi vaccine
NZ596500A (en) Pneumococcal polysaccharide conjugate vaccine
WO2000037105A3 (en) Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
AU2001244275A1 (en) Pneumococcus polysaccharide conjugates for use as vaccine against tetanus and diphtheria
ZA969951B (en) Recombinat live vaccine based on feline herpesvirus type 1, especially against feline infectious peritonitis.
AU5577201A (en) Immunogenic pneumococcal protein and vaccine compositions thereof
WO2002034773A3 (en) Streptococcal genes
WO2001078787A3 (en) Lipopolysaccharide-conjugate vaccine for sepsis treatment
WO2002050107A3 (en) Streptococcus pyogenes antigens and corresponding dna fragments
AU7193501A (en) Multiple antigenic peptides immunogenic against streptococcus pneumoniae
WO2000047227A3 (en) Mycobacterium tuberculosis, immunization
Anderson Immunogenic conjugates.
HK1057697A (en) Vaccine against streptococcus pneumoniae
김성태 Fantasy/Fantastic
饶志芳 Epson Stylus Color 740
铭铭 HP DeskJet 610C
Cleary et al. Streptococcal C 5 a peptidase vaccine
DE60031106D1 (de) Fluordesoxyuridin-resistente streptococcus gordonii stämme